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BOYTE CONG HOA xA HOI CHU NGHiA VIET NAM
. . .
DQe l~p - Tlf do - H~nh phue
s6: 1..D 120211TT-BYT Ha Ne}i,ngay 30 thang 6 ndm 2021
THONGTU
Quy djnh Danh muc eh~t e~m sir dung trong san xu~t, kinh doanh
thuc ph~m bao v~ sue khoe
Can ctr Ludt an toan thuc phdm ngay 17thang 6 ndm 2010;
Can cu Nghf afnh s6 15/2018/ND-CP ngay 02 thdng 02 nam 2018 cua
Chinh phu Quy dinh chi tiit thi hanh mot s6ai~u cua Ludt An toan thuc phdm;
Can ctrNghi dinh s6 75/2017/ND-CP ngay 20 thang 6 ndm 2017 cua Chinh
phu Quy dinh chtec nang, nhiem V?/,quyen han va co cdu t6 chuc cua Be}Y ti;
Thea a~ nghi cua C?/Ctruong C?/C
An toan thuc phdm;
Be} truong B(J Y ti ban hanh Thong tu quy dinh Danh muc chdt cdm sir
dung trong scm xudt, kinh doanh thuc phdm baa v¢ sire khoe.
Di~u 1.Pham vi di~u chinh va d8i nrong ap dung
1. Thong tir nay quy dinh Danh muc chfrt cfrm su dVng trong san xUfrt,
kinh doanh thIc ph~m bao v~ suc kh6e.
2. Thong tu mly ap dVng d6i vai t6 chuc, ca nhan Vi~t Nam; t6 chuc, ca
nhan nuac ngoai t~i Vi~t Nam tham gia san xUfrt,kinh doanh thIc ph~m bao v~
suc kh6e; t6 chuc, ca nhan co hOC;lt
d9ng lien quan dSn thIc ph~m bao v~ suc kh6e
t?i Vi~tNam.
Di~u 2. Nguyen t~e xiiy dlfng Danh ml]e eh~t e~m sir dl]ng trong san
xu~t, kinh doanh thl}'e ph~m bao v~ sue khoe
1. Bao dam phil hqp vai cac quy dinh cua phap lu?t va co cO'sakhoa hQC.
2. Phil hqp vai thong I~ qu6c tS va thIc tiSn quan Iy an toan thIc ph~m t~i
Vi~tNam.
3. Kip thai C?Pnh?t, sua d6i, b6 sung Danh mvc dS dap Ung yeu c~u bao v~
suc kh6e va yeu c~u quan Iy nha nuac.
4. Chfrt dua vao Danh mvc la chfrt co kha nang gay h~i dSn suc kh6e ho~c
tinh m~ng nguai su dVngho~c cac chfrtkhong thu9c lo~i dUngtrong thIc ph~m.
'., !
2
Di~u 3. Danh muc ch~t c~m Stf dung trong san xu~t, kinh doanh thuc
phjrn bao v~ sire khoe
Ch~t cam sir dung trong san xu~t, kinh doanh thtrc pham bao v~ sire
khoe, bao g6m ch~t co trong cac Danh muc sau:
1. Phu luc V "Danh muc thuoc, nguyen lieu him thuoc cam nhap khau,
earn san xuat" ban hanh kern thea Nghi dinh s6 54/2017IND-CP ngay 08 thang
5 nam 2017 cua Chinh phu quy dinh chi tiSt mot s6 dieu va bien phap thi hanh
Luat duoc.
2. Danh muc I "Cac ch~t rna tuy tuyet d6i c~m su dung trong y hQCva doi
song xa hoi; Viec su dung cac ch~t nay trong phan tich, kiem nghiem, nghien
ciru khoa hoc, diSu tra tQi pham thea quy dinh d~c biet cua co quan co tham
quyen"; Danh muc II "Cac ch~t rna tuy duQ'cdung h~n chS trong phan Hch, kiSm
nghi~m, nghien Clru khoa hQc, diSu tra tQi ph~m ho~c trong lInh vlc Y tS thea
quy dinh cua cO'quan co th~m quySn"; Danh mlc III "Cac ch~t rna tuy duQ'c
dung trong phan tich, kiSm nghi~m, nghien Clrukhoa hQc, diSu tra tQiph~m ho~c
trong lInh VlCYtS, thu y thea quy dinh cua cO'quan co th~m quySn"; Danh mlc
IVA "Cac tiSn ch~t thiSt ySu, tham gia vao c~u truc ch~t rna tuy" ban hanh kern
thea Nghi dinh s6 73/2018IND-CP ngay 15 thang 5 nam 2018 cua Chinh phu
quy dinh cac danh mlc ch~t rna tuy va tiSn ch~t.
3. Phl llc I "Danh mlC duQ'cch~t gay nghi~n" ban hanh kern thea Thong
tu s6 20/20 17/TT-BYT ngay 10 thang 5 nam 2017 cua BQ truOng BQ Y tS Quy
dinh chi tiSt mQt s6 diSu cua Lu~t duQ'cva Nghi dinh s6 54/20171ND-CP ngay
08 thang 5 nam 2017 cua Chinh phu vS thu6c va nguyen li~u lam thu6c phai
kiSm soM d~c bi~t.
4. Danh mlc Thu6c dQCva nguyen li~u dQc lam thu6c ban hanh kern thea
Thong tu s6 06/20 17/TT-BYT ngay 03 thang 5 nam 2017 cua BQ truOng BQ Y
tS ban hanh Danh mlc Thu6c dQcva nguyen li~u dQclam thu6c.
5. Phlllc I "Danh mlc duQ'cli~u co dQcHnh ngu6n g6c thgc v~t"; Phlllc
II "Danh mlc duQ'c li~u co dQc tinh ngu6n g6c dQng v~t"; Phl llc III "Danh
mlc duQ'cli~u co dQc tinh ngu6n g6c khoang v~t" ban hanh kern thea Thong tu
s6 42/2017/TT-BYT ngay 13 thang 11 nam 2017 cua BQ truOng BQ Y tS Ban
hanh Danh mlc duQ'c li~u dQc lam thu6c, tru cac duQ'c li~u co d~u (*) da duQ'c
chS biSn thea dung phuO'llg phap chS biSn do BQ truOng BQ Y tS quy dinh t~i
Thong tu s6 30/2017/TT-BYT ngay 11 thang 7 nam 2017 hUOng dfin phuO'llg
phap chS biSn cac vi thu6c c6 tluySn va bao dam an toan khi lam thlc ph~m.
6. Danh mlCcac ch~t co trong Phlllc ban hanh kern thea Thong tu nay.
" '
3
f)i~u 4. Hi~u lfc thi hanh
1. Thong tir nay co hieu hrc thi hanh kS til ngay 01 thang 9 nam 2021.
2. Truong hop cac van ban quy pham phap luat diroc d&n chieu trong
Thong nr nay co S17
thay d6i, b6 sung hoac duoc thay thS thi ap dung thirc hien
theo quy dinh tai van ban maio
f)i~u 5. TB chtrc tlnrc hi~n
1. Cue An toan thuc pham (B9 Y tS) co trach nhiem:
a) Chu tri phoi hop voi cac don vi co lien quan quan ph6 bien, huang d&n
va trien khai thuc hien Thong nr nay;
b) Chi dao cac don vi tham gia kiem nghiem th17Cpham bao v~ sire khoe
xay dung phuong phap, d~u nr nhan lire, trang thiet bi kiern nghiem dS dap ling
yeu c~u kiem nghiem cac chat co trong Danh muc ch~t c~m quy dinh tai Thong
tir nay.
2. So' Y tS, Ban Quan Iy an toan thirc pham cac tinh, thanh ph6 tr17cthu9c
trung uong co trach nhi~m t6 chuc th17chi~n, So' Y tS chi d?o cac Chi cvc An
toan v~ sinh th17cph§.mva cac don vi lien quan kiSm tra va giam sat cac t6 chuc,
ca nhan san xu~t, kinh doanh th17cph§.mbao v~ suc khoe t?i dia phuong.
Trong qua trinh th17chi~n Thong tu nay, nSu co kho khan, vuang m~c dS
nghi cac cO'quan, t6 chuc, ca nhan bao cao vS B9 Y tS (Cvc An toan th17cph§.m)
dS xem xet, giai quySt./.
Noi nhq.n:
- Uy ban v€ Cac vfrn d€ xii hQi cila Qu6c hQi;
- Viin phOng Chinh phil (Phong Cong bao, C6ng
TTDTCP);
- BQtnrang Nguy~n Thanh Long (d~ b/c);
- Cac Thu tnrang BQ Y t8;
- Cac BQ, cO'quan ngang BQ, cO'quan thuQc Chinh phil;
- UBND cac tinh, Thanh ph6 tn!c thuQc TW;
- BQ Tu phap (Cl,lC Ki~m tra VBQPPL);
- Cac Vv, Cvc, Viin phOng BQ, Thanh tra BQ,
T6ng cvc thuQc BQ Y t8;
- Cac dan vi tn!c thuQc BQ Y t8;
- Y t8 cac nganh;
- So' Y t8 cac tinh, thanh ph6 tn!c thuQc TW;
- Ban Quan Iy an toan thlJc phfrm, Chi cvc an toan v~ sinh
thlJc phfrm cac tinh, thanh ph6 trlJc thuQc TW;
- Luu: VT, ATTP(02b),PC(02b)
TrU'O'ng Quac CU'irug
BOYTE CONG HOA xA HOI CHiT NGHiA VIET NAM
. . .
DQc I~p - Tlf do - H~nh phuc
PHULUC
DANH Ml)C CAC CHAT
(Banhanh kern thea Thong tus6 120211TT-BYTngay thang ndm 2021)
STT Ten chat Ten khoa hoc
1 1-3-dimethylamylamine 4-methy lhexan- 2-amine
2 Aildenafil S-[5-[(3S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl-2-ethoxyphenyl]-
I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7 -one
3 Aminotadalafil (2R,8R)-6-amino-2-(1,3-benzodioxol-S-yl)-3,6,17-
triazatetracyclo[8. 7.0.03,8.011, 16]heptadeca-l (10), 11,13, IS-
tetraene-4, 7-dione
4 Aromatase Aminogluteth 3-(4-aminophenyl)- 3-ethylpiperidine- 2,6-dione
inhibitor imide
Formestane (8R,9S, lOR, 13S,14S)-4-hydroxy-l 0, 13-dimethyl-
2,6,7,8,9,11,12,14, 15,16-decahydro-lH-cyclopenta[a]phenanthrerre-
3,17-dione I
Anastrozole 2-[3-(2-cyanopropan-2-yl)-S-(1 ,2,4-triazol-l-ylmethyl) phenyl]-2-
methylpropanenitrile
Letrozole 4-[(4-cyanophenyl)-(1 ,2,4-triazol-l-yl)methyl]benzonitrile
Vorozole 6-[(4-chlorophenyl)-(1 ,2,4-triazol-l-yl)methyl]-I-
methylbenzotriazole
I
Exemestane 6- Methyleneandrosta -1,4-diene-3,17-dione
(8R,9S,1 OR,13S,14S)-10,13-dimethyl-6-methylidene-
7,8,9,11,12,14, IS, 16-octahydrocyclopenta[ a]phenanthrene- 3,17-
dione
S Beclomethasone (8S,9R, lOS,11S,13S,14S, 16S,17R)-9-chloro-ll, 17-dihydroxy-17 -(2-
hydroxyacetyl)-10,13,16-trimethyl-6,7,8, 11,12,14,15,16- I
octahydrocyclopenta[ a[phenanthren- 3-one
6 Benproperine 1-[I-(2-benzylphenoxy)propan-2-yl]piperidine I
7 Benzamidenafil N-[(3,4-dimethoxyphenyl)methyl]-2-(I-hydroxypropan-2-ylamino)-
S-nitrobenzamide
8 Benzyl sibutramine 1-(1-(4-chlorophenyl)cyclobutyl)-N ,N-dimethyl-2-phenylethan-l-
amine
I
9 Betamethasone (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-ll,17-dihydroxy-17-(Q-
hydroxyacetyl)-1 0,13,16-trimethyl-6,7,8, 11,12,14,15,16- I
octahydrocyclopenta[ a[phenanthren- 3-one
10 Budesonide (1S,2S,4R,8S,9S,11 S,12S,13R)-II-hydroxy-8-(2-hydroxyacetyl)-
9, 13-dimethyl-6-propyl-S, 7-dioxapentacyclo
[10.8.0.02,9.04,8.013, 18]icosa-14, 17-dien-16-one
11 Buformin 2-butyl-1-( diaminomethylidene )guanidine
12 Cetilistat 2-hexadecoxy -6-methy 1-3,1-benzoxazin-4-one
13 Chlorpheniramine 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-l-amine
14 Chlorpromazine 3-(2-chlorophenothiazin-l O-yl)-N,N-dimethylpropan-l-amine
IS Chlorzoxazone S-chloro-3H -1,3-benzoxazol-2-one
16 Cinnarizine I-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
2
17 Clobetasol propionate [(8S,9R, lOS,11S, 13S,14S, 16S, 17R)-17-(2-chloroacetyl)-9-fluoro-
II-hydroxy-l 0, 13,16-trimethyl-3-oxo-6, 7,8,11,12,14,15,16-
octahydrocyclopenta[ a]phenanthren-l 7-yl] propanoate
18 Colchicine N-[(7S)-1 ,2,3, 10-tetramethoxy-9-oxo-6, 7-dihydro-5H-
benzo [a]heptalen-7-yl] acetamide
19 Cortisone (8S,9S, lOR, 13S, 14S,17R)-17 -hydroxy-17 -(2-hydroxyacetyl)-1O, 3-
dimethyl-l ,2,6,7,8,9,12,14,15,16-
decahydrocyclopenta[ a]phenanthrene-3, l l-dione
20 Cyproheptadine I-methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-l (15),3,5,7,9, 11,13-1
heptaenylidene )piperidine
21 Dapoxetine (1S)-N,N-dimethyl-3-naphthalen-l-yloxy-l-phenylpropan-l_amiqe
22 Deflazacort [2-[(1 S,2S,4R,8S,9S, 11S,12S, 13R)-II-hydroxy-6,9, 13-trimethyl-16-
oxo-5-oxa-7-azapentacyclo[1 0.8.0.02,9.04, 8.013,18]icosa-6, 14,1r-
trien-8-yl]-2-oxoethyl] acetate
23 Desisobutyl- 1-[1-(4-chlorophenyl)cyclobutyl]-N,N-dimethyl-2-
I
benzylsibutramine phenylethanamine
24 Desmethyl carbodenafil 5-[2-ethoxy-5-( 4-methylpiperazine-l-carbonyl)phenyl]-I-methyl_3_
propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one I
25 Desmethylsibutramine 1-[1-(4-chlorophenyl )cyclo buty I]-N,3 -dimethyl butan-l-amine
1
26 Desmethylsildenafil 5-(2-ethoxy-5-piperazin-l-ylsulfonylphenyl)-I-methyl-3-propyl-6H-
pyrazolo[ 4,3-d]pyrimidin-7 -one
I
27 Dexamethasone (8S,9R,1 OS,11S,13S,14S,16R,17R)-9-fluoro-l1 ,17-dihYdrOxY-17-i(2-
hydroxyacetyl)-1 0,13,16-trimethyl-6,7,8, 11,12,14,15,16-
octahydrocyclopenta[ a]phenanthren -3-one
28 Diclofenac [2-[(2,6-dichlorophenyl)amino ]phenyl]acetatic acid
29 Diclofenac Sodium Sodium 2-[(2,6-dichlorophenyl)amino]phel!Yl]acetate I
30 Didesmethylsibutramine 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-l-amine I
31 Dimethylacetildenafil S-[ 5-[2-[ (3S,SR)-3,S-dimethylpiperazin-l-yl]acetyl]-2-
ethoxyphenyl]-I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7i
one
32 Dithiodesmethylcarboden S-[2-ethoxy-S-( 4-methylpiperazine-l-carbothioyl)phenyl]-I-meth*l_
afil 3-propyl-4H-pyrazolo[ 4,3-d]pyrimidine-7 -thione
33 Doxepin (3E)-3-(6H-benzo[ c][1]benzoxepin-l1-ylidene)-N,N-
I
dimethylpropan-l-amine
34 Ephedrine ephedrine (1R,2S)-2-(methylamino )-I-phenylpropan-l-01
I
alkaloids pseudoephedr (1S,2S)-2-(methylamino )-I-phenylpropan-l-01
ine
norephedrine (1S,2R)-2-amino-l-phenylpropan-l-01
I
norpseudoeph (1S,2S)-2-amino-1-phenylpropan-l-01 I
edrine
35 Fenfluramine N-ethyl-1- [3-(trifluoromethy I)phenyl ]propan- 2-amine
36 Flibanserin 3-[2-[ 4-[3-(trifluoromethyl)phenyl]piperazin-l-yl]ethyl]_1 H-
benzimidazol-2-one
I
37 FIudrocortisone (8S,9R,IOS,11 S,13S,14S,17R)-9-fluoro-ll,17-dihydroxy-17-(2_
hydroxyacetyl)-1 0, 13-dimethyl-l ,2,6,7,8,11,12,14, IS,16-
decahydrocyclopenta[ a]phenanthren- 3-one
38 Fluocinolone (6S,8S,9R, lOS,11S,13S,14S, 16R, 17S)-6,9-difluoro-ll, 16,17-
trihydroxy-17-(2-hydroxyacetyl)-1 0, 13-dimethyl-6, 7,8,
11,12,14,15, 16-octahydrocyclopenta[ a]phenanthren- 3-one
39 Fluocinonide [2-[(1 S,2S,4R,8S,9S, 11S,12R, 13S, 19S)-12, 19-difluoro-11-hydroxy-
6,6,9, 13-tetramethyl-16-oxo-S, 7-dioxapentacyclo
[10.8.0.02,9.04,8.013, 18]icosa-14, 17-dien-8-yl]-2-oxoethyl] acetate
3
40 Fluorometholone (6S,8S,9R,1 OS,11S,l3S, 14S, 17R)-17-acetyl-9-fluoro-ll, 17-
I
dihydroxy-6,1 0,13-trimethyl-6, 7,8,11,12,14, 15,16-
octahydrocyclopenta[ a]phenanthren -3-one
41 Fluoxetine N-methyl-3-phenyl-3-[ 4-(trifluoromethyl)phenoxy ]propan-l-amine
42 Fluticasone S-(fluoromethyl) (6S,8S,9R,1 OS,11S, 13S, 14S,16R, 17R) -6,9-
difluoro-ll, 17-dihydroxy-l 0, 13,16-trimethyl-3-oxo-
6,7,8,11,12,14,15, 16-octahydrocyclopenta[ a] phenanthrene-17-
carbothioate
43 Furosemide 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid I
44 Hydrochlorothiazide 6-chloro-l, I-dioxo- 3,4-dihydro- 2H-llambda6,2,4-benzothiadiazire-
7-sulfonamide
45 Hydrocortisone (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17_(2_
hydroxyacetyl)-1 0,l3-dimethyl-2,6, 7,8,9,11,12,14,15, 16-decahydro-
1H-cyclopenta[ a]phenanthren- 3-one I
46 Hydroxyhomosildenafil 5-[2-ethoxy-5-[ 4-(2-hydroxyethyl)piperazin-l-yl]sulfonylphenyl]L 1-
methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
47 Hydroxyacetildenafil 5-[2-ethoxy-5-[2-[ 4-(2-hydroxyethyl)piperazin-l-yl]acetyl] Phen11]-
I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7 -one
48 Ibuprofen 2-[4-(2-methylpropyl)phenyl]propanoic acid
49 Indomethacin 2-[1-( 4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
50 Ketoprofen 2-(3-benzoylphenyl)propanoic acid
51 Lorcaserin (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-lH-3-benzazepine
I
52 Metformin 3-(diaminomethylidene )-1, I-dimethylguanidine
53 Methocarbamol [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate
54 Methylprednisolone (6S,8S,9S,10R,IIS,13S,14S,17R)-11,17-dihydroxy_17_(2_ I
hydroxyacetyl)-6, 10,13-trimethyl-7,8,9, 11,12,14,15,16 -octahydr9-
6H-cyclopenta[ a]phenanthren -3-one
55 Mometasone (8S,9R,10S,11 S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)_
11,17-dihydroxy-l0,13,16-trimethyl-6,7,8, 11,12,14,15,16-
octahydrocyclopenta[ a]phenanthren- 3-one
56 Naproxen (2S)-2-( 6-Methoxynaphthalen-2-yl )propanoic acid
57 N-Desmethyl tadalafil (2R,8R)-2-(1 ,3-benzodioxol-5-yl)-3,6, 17-triazatetracyclo
[8.7.0.03,8.011, 16]heptadeca-l (10), 11,13, 15-tetraene-4, 7-dione
58 N-Desmethyl-N-benzyl 5-[5-(4-benzylpiperazin-l-yl)sulfonyl-2-ethoxyphenyl]_I_methy1-3-
sildenafil propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7-one I
59 N-Desmethylvardenafil 2-[2-ethoxy-5-( 4-methylpiperazin-l-yl)sulfonylphenyl]-5-methyl_7_
propyl-3H-imidazo[ 5,I-f] [1,2,4]triazin-4-one
60 Nefopam 5-methyl-l-phenyl-l ,3,4,6-tetrahydro-2,5-benzoxazocine
61 Orlistat [(2S)-I-[(2S,3 S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2- I
formamido-4-methylpentanoate
62 Phenformin 1-(diaminomethylidene )-2-(2-phenylethyl)guanidine
63 Phenytoin 5,5-Diphenylimidazolidine- 2,4-dione
64 Piperadino vardenafil 2-[2-ethoxy-5-(piperidine-l-sulfonyl)-phenyl]-5_methyl-7 -propyl-
3H-imidazo[5, I-f]-[1,2,4]triazin-4- one
65 Piroxicam 4-hydroxy-2-methyl-l, I-dioxo-N-pyridin-2-yl-l1ambda6,2-
benzothiazine- 3-carboxamide
66 Prednisolone (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy_17_(2_ I
hydroxyacetyl)-1 0, 13-dimethyl-7,8,9, 11,12,14,15, 16-octahydro-6H-
cyclopenta[ a]phenanthren-3-one
67 Prednisone (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-
dimethyl-6, 7,8,9,12,14,15, 16-octahydrocyclopenta[ a]Phenanthrener
3,II-dione
·
. ,'l , r ,>
4
68 Propranolol (2RS)-I-[(Propan-2-yl)amino ]-3-[(naphthalen-l-
yl)oxy]propan-2-o1
I
69 Salbutamol (lRS)-2-[(I, I-Dimethylethyl)amino ]-1-[ 4-hYdrOxY-3t
(hydroxymethyl)phenyl]ethanol
70 Salmeterol 2-(hydroxymethyl)-4-[I-hydroxy-2-[6_( 4-
J
phenylbutoxy)hexylamino ]ethyl]phenol
71 Sildenafil S-[2-ethoxy-S-( 4-methylpiperazin-l-
I
yl)sulfonylphenyl]-I-methyl-3-propyl-6H_
pyrazolo[ 4,3-d]pyrimidin-7 -one
I
72 Sulfoaildenafil S-[S-[(3S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl_2_1
ethoxyphenyl]-I-methyl-3-propyl-4H-pyrazolo[ 4,3-
d]pyrimidine-7 -thione
73 Sulfohydroxyhomosildenafil S-[2-ethoxy-S-[ 4-(2-hydroxyethyl)piperazin-l-
I
yl]sulfonylphenyl]-I-methyl-3-propyl-4H_
pyrazolo[ 4,3-d]pyrimidine-7 -thione
74 Tadalafil (6R, 12aR)-6-(1 ,3-Benzodioxol-S-yl)-2-methyl-
2,3,6,7,12, 12a-hexahydropyrazino[I',2': 1,6]-
I
pyrido[3,4-b ]indole-l ,4-dione
7S Terazosin hydrochloride 1-(4-Amino-6, 7-dimethoxyquinazolin-2-yl)-4-
[[(2RS)-tetrahydrofuran-2-yl]carbonyl]piperazine
i
hydrochloride
76 Testosterone (8R,9S,1 OR,13S,14S,17S)-17-hydroxy-l 0,13-
dimethyl-l ,2,6,7,8,9, 11,12,14, IS, 16,17-
dodecahydrocyclopenta[ a]phenanthren- 3-one
77 Thioaidenafil
S-[S-[(3 S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl_2_
ethoxyphenyl]-I-methyl-3-propyl-6H-pyrazolo[ 4,3-
d]pyrimidine-7 -thione
I
78 Thiosildenafil S-[2-ethoxy-S-( 4-methylpiperazin-l-
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yl)sulfonylphenyl]-I-methyl-3-propyl_6H_
pyrazolo[ 4,3-d]pyrimidine-7 -thione
79 Triamcinolone
9a -Fluoro-ll~,16a,17a,21-tetrahydroxypregna_l ,4-
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diene-3,20-dione
80 Vardenafil 1-{[3-(3,4-Dihydro-S-methyl-4-oxo-7-
propylimidazo[S,I-fJ-as-triazin-2-yl)-4_
ethoxyphenyl] sulfonyl }-4-ethylpiperazine
Truong Qu8e Cmyng

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Thông tư số:10/2021/TT-BYT quy định danh mục chất cấm sử dụng trong sản xuất, kinh doanh thực phẩm bảo vệ sức khỏe

  • 1. BOYTE CONG HOA xA HOI CHU NGHiA VIET NAM . . . DQe l~p - Tlf do - H~nh phue s6: 1..D 120211TT-BYT Ha Ne}i,ngay 30 thang 6 ndm 2021 THONGTU Quy djnh Danh muc eh~t e~m sir dung trong san xu~t, kinh doanh thuc ph~m bao v~ sue khoe Can ctr Ludt an toan thuc phdm ngay 17thang 6 ndm 2010; Can cu Nghf afnh s6 15/2018/ND-CP ngay 02 thdng 02 nam 2018 cua Chinh phu Quy dinh chi tiit thi hanh mot s6ai~u cua Ludt An toan thuc phdm; Can ctrNghi dinh s6 75/2017/ND-CP ngay 20 thang 6 ndm 2017 cua Chinh phu Quy dinh chtec nang, nhiem V?/,quyen han va co cdu t6 chuc cua Be}Y ti; Thea a~ nghi cua C?/Ctruong C?/C An toan thuc phdm; Be} truong B(J Y ti ban hanh Thong tu quy dinh Danh muc chdt cdm sir dung trong scm xudt, kinh doanh thuc phdm baa v¢ sire khoe. Di~u 1.Pham vi di~u chinh va d8i nrong ap dung 1. Thong tir nay quy dinh Danh muc chfrt cfrm su dVng trong san xUfrt, kinh doanh thIc ph~m bao v~ suc kh6e. 2. Thong tu mly ap dVng d6i vai t6 chuc, ca nhan Vi~t Nam; t6 chuc, ca nhan nuac ngoai t~i Vi~t Nam tham gia san xUfrt,kinh doanh thIc ph~m bao v~ suc kh6e; t6 chuc, ca nhan co hOC;lt d9ng lien quan dSn thIc ph~m bao v~ suc kh6e t?i Vi~tNam. Di~u 2. Nguyen t~e xiiy dlfng Danh ml]e eh~t e~m sir dl]ng trong san xu~t, kinh doanh thl}'e ph~m bao v~ sue khoe 1. Bao dam phil hqp vai cac quy dinh cua phap lu?t va co cO'sakhoa hQC. 2. Phil hqp vai thong I~ qu6c tS va thIc tiSn quan Iy an toan thIc ph~m t~i Vi~tNam. 3. Kip thai C?Pnh?t, sua d6i, b6 sung Danh mvc dS dap Ung yeu c~u bao v~ suc kh6e va yeu c~u quan Iy nha nuac. 4. Chfrt dua vao Danh mvc la chfrt co kha nang gay h~i dSn suc kh6e ho~c tinh m~ng nguai su dVngho~c cac chfrtkhong thu9c lo~i dUngtrong thIc ph~m.
  • 2. '., ! 2 Di~u 3. Danh muc ch~t c~m Stf dung trong san xu~t, kinh doanh thuc phjrn bao v~ sire khoe Ch~t cam sir dung trong san xu~t, kinh doanh thtrc pham bao v~ sire khoe, bao g6m ch~t co trong cac Danh muc sau: 1. Phu luc V "Danh muc thuoc, nguyen lieu him thuoc cam nhap khau, earn san xuat" ban hanh kern thea Nghi dinh s6 54/2017IND-CP ngay 08 thang 5 nam 2017 cua Chinh phu quy dinh chi tiSt mot s6 dieu va bien phap thi hanh Luat duoc. 2. Danh muc I "Cac ch~t rna tuy tuyet d6i c~m su dung trong y hQCva doi song xa hoi; Viec su dung cac ch~t nay trong phan tich, kiem nghiem, nghien ciru khoa hoc, diSu tra tQi pham thea quy dinh d~c biet cua co quan co tham quyen"; Danh muc II "Cac ch~t rna tuy duQ'cdung h~n chS trong phan Hch, kiSm nghi~m, nghien Clru khoa hQc, diSu tra tQi ph~m ho~c trong lInh vlc Y tS thea quy dinh cua cO'quan co th~m quySn"; Danh mlc III "Cac ch~t rna tuy duQ'c dung trong phan tich, kiSm nghi~m, nghien Clrukhoa hQc, diSu tra tQiph~m ho~c trong lInh VlCYtS, thu y thea quy dinh cua cO'quan co th~m quySn"; Danh mlc IVA "Cac tiSn ch~t thiSt ySu, tham gia vao c~u truc ch~t rna tuy" ban hanh kern thea Nghi dinh s6 73/2018IND-CP ngay 15 thang 5 nam 2018 cua Chinh phu quy dinh cac danh mlc ch~t rna tuy va tiSn ch~t. 3. Phl llc I "Danh mlC duQ'cch~t gay nghi~n" ban hanh kern thea Thong tu s6 20/20 17/TT-BYT ngay 10 thang 5 nam 2017 cua BQ truOng BQ Y tS Quy dinh chi tiSt mQt s6 diSu cua Lu~t duQ'cva Nghi dinh s6 54/20171ND-CP ngay 08 thang 5 nam 2017 cua Chinh phu vS thu6c va nguyen li~u lam thu6c phai kiSm soM d~c bi~t. 4. Danh mlc Thu6c dQCva nguyen li~u dQc lam thu6c ban hanh kern thea Thong tu s6 06/20 17/TT-BYT ngay 03 thang 5 nam 2017 cua BQ truOng BQ Y tS ban hanh Danh mlc Thu6c dQcva nguyen li~u dQclam thu6c. 5. Phlllc I "Danh mlc duQ'cli~u co dQcHnh ngu6n g6c thgc v~t"; Phlllc II "Danh mlc duQ'c li~u co dQc tinh ngu6n g6c dQng v~t"; Phl llc III "Danh mlc duQ'cli~u co dQc tinh ngu6n g6c khoang v~t" ban hanh kern thea Thong tu s6 42/2017/TT-BYT ngay 13 thang 11 nam 2017 cua BQ truOng BQ Y tS Ban hanh Danh mlc duQ'c li~u dQc lam thu6c, tru cac duQ'c li~u co d~u (*) da duQ'c chS biSn thea dung phuO'llg phap chS biSn do BQ truOng BQ Y tS quy dinh t~i Thong tu s6 30/2017/TT-BYT ngay 11 thang 7 nam 2017 hUOng dfin phuO'llg phap chS biSn cac vi thu6c c6 tluySn va bao dam an toan khi lam thlc ph~m. 6. Danh mlCcac ch~t co trong Phlllc ban hanh kern thea Thong tu nay.
  • 3. " ' 3 f)i~u 4. Hi~u lfc thi hanh 1. Thong tir nay co hieu hrc thi hanh kS til ngay 01 thang 9 nam 2021. 2. Truong hop cac van ban quy pham phap luat diroc d&n chieu trong Thong nr nay co S17 thay d6i, b6 sung hoac duoc thay thS thi ap dung thirc hien theo quy dinh tai van ban maio f)i~u 5. TB chtrc tlnrc hi~n 1. Cue An toan thuc pham (B9 Y tS) co trach nhiem: a) Chu tri phoi hop voi cac don vi co lien quan quan ph6 bien, huang d&n va trien khai thuc hien Thong nr nay; b) Chi dao cac don vi tham gia kiem nghiem th17Cpham bao v~ sire khoe xay dung phuong phap, d~u nr nhan lire, trang thiet bi kiern nghiem dS dap ling yeu c~u kiem nghiem cac chat co trong Danh muc ch~t c~m quy dinh tai Thong tir nay. 2. So' Y tS, Ban Quan Iy an toan thirc pham cac tinh, thanh ph6 tr17cthu9c trung uong co trach nhi~m t6 chuc th17chi~n, So' Y tS chi d?o cac Chi cvc An toan v~ sinh th17cph§.mva cac don vi lien quan kiSm tra va giam sat cac t6 chuc, ca nhan san xu~t, kinh doanh th17cph§.mbao v~ suc khoe t?i dia phuong. Trong qua trinh th17chi~n Thong tu nay, nSu co kho khan, vuang m~c dS nghi cac cO'quan, t6 chuc, ca nhan bao cao vS B9 Y tS (Cvc An toan th17cph§.m) dS xem xet, giai quySt./. Noi nhq.n: - Uy ban v€ Cac vfrn d€ xii hQi cila Qu6c hQi; - Viin phOng Chinh phil (Phong Cong bao, C6ng TTDTCP); - BQtnrang Nguy~n Thanh Long (d~ b/c); - Cac Thu tnrang BQ Y t8; - Cac BQ, cO'quan ngang BQ, cO'quan thuQc Chinh phil; - UBND cac tinh, Thanh ph6 tn!c thuQc TW; - BQ Tu phap (Cl,lC Ki~m tra VBQPPL); - Cac Vv, Cvc, Viin phOng BQ, Thanh tra BQ, T6ng cvc thuQc BQ Y t8; - Cac dan vi tn!c thuQc BQ Y t8; - Y t8 cac nganh; - So' Y t8 cac tinh, thanh ph6 tn!c thuQc TW; - Ban Quan Iy an toan thlJc phfrm, Chi cvc an toan v~ sinh thlJc phfrm cac tinh, thanh ph6 trlJc thuQc TW; - Luu: VT, ATTP(02b),PC(02b) TrU'O'ng Quac CU'irug
  • 4. BOYTE CONG HOA xA HOI CHiT NGHiA VIET NAM . . . DQc I~p - Tlf do - H~nh phuc PHULUC DANH Ml)C CAC CHAT (Banhanh kern thea Thong tus6 120211TT-BYTngay thang ndm 2021) STT Ten chat Ten khoa hoc 1 1-3-dimethylamylamine 4-methy lhexan- 2-amine 2 Aildenafil S-[5-[(3S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl-2-ethoxyphenyl]- I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7 -one 3 Aminotadalafil (2R,8R)-6-amino-2-(1,3-benzodioxol-S-yl)-3,6,17- triazatetracyclo[8. 7.0.03,8.011, 16]heptadeca-l (10), 11,13, IS- tetraene-4, 7-dione 4 Aromatase Aminogluteth 3-(4-aminophenyl)- 3-ethylpiperidine- 2,6-dione inhibitor imide Formestane (8R,9S, lOR, 13S,14S)-4-hydroxy-l 0, 13-dimethyl- 2,6,7,8,9,11,12,14, 15,16-decahydro-lH-cyclopenta[a]phenanthrerre- 3,17-dione I Anastrozole 2-[3-(2-cyanopropan-2-yl)-S-(1 ,2,4-triazol-l-ylmethyl) phenyl]-2- methylpropanenitrile Letrozole 4-[(4-cyanophenyl)-(1 ,2,4-triazol-l-yl)methyl]benzonitrile Vorozole 6-[(4-chlorophenyl)-(1 ,2,4-triazol-l-yl)methyl]-I- methylbenzotriazole I Exemestane 6- Methyleneandrosta -1,4-diene-3,17-dione (8R,9S,1 OR,13S,14S)-10,13-dimethyl-6-methylidene- 7,8,9,11,12,14, IS, 16-octahydrocyclopenta[ a]phenanthrene- 3,17- dione S Beclomethasone (8S,9R, lOS,11S,13S,14S, 16S,17R)-9-chloro-ll, 17-dihydroxy-17 -(2- hydroxyacetyl)-10,13,16-trimethyl-6,7,8, 11,12,14,15,16- I octahydrocyclopenta[ a[phenanthren- 3-one 6 Benproperine 1-[I-(2-benzylphenoxy)propan-2-yl]piperidine I 7 Benzamidenafil N-[(3,4-dimethoxyphenyl)methyl]-2-(I-hydroxypropan-2-ylamino)- S-nitrobenzamide 8 Benzyl sibutramine 1-(1-(4-chlorophenyl)cyclobutyl)-N ,N-dimethyl-2-phenylethan-l- amine I 9 Betamethasone (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-ll,17-dihydroxy-17-(Q- hydroxyacetyl)-1 0,13,16-trimethyl-6,7,8, 11,12,14,15,16- I octahydrocyclopenta[ a[phenanthren- 3-one 10 Budesonide (1S,2S,4R,8S,9S,11 S,12S,13R)-II-hydroxy-8-(2-hydroxyacetyl)- 9, 13-dimethyl-6-propyl-S, 7-dioxapentacyclo [10.8.0.02,9.04,8.013, 18]icosa-14, 17-dien-16-one 11 Buformin 2-butyl-1-( diaminomethylidene )guanidine 12 Cetilistat 2-hexadecoxy -6-methy 1-3,1-benzoxazin-4-one 13 Chlorpheniramine 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-l-amine 14 Chlorpromazine 3-(2-chlorophenothiazin-l O-yl)-N,N-dimethylpropan-l-amine IS Chlorzoxazone S-chloro-3H -1,3-benzoxazol-2-one 16 Cinnarizine I-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
  • 5. 2 17 Clobetasol propionate [(8S,9R, lOS,11S, 13S,14S, 16S, 17R)-17-(2-chloroacetyl)-9-fluoro- II-hydroxy-l 0, 13,16-trimethyl-3-oxo-6, 7,8,11,12,14,15,16- octahydrocyclopenta[ a]phenanthren-l 7-yl] propanoate 18 Colchicine N-[(7S)-1 ,2,3, 10-tetramethoxy-9-oxo-6, 7-dihydro-5H- benzo [a]heptalen-7-yl] acetamide 19 Cortisone (8S,9S, lOR, 13S, 14S,17R)-17 -hydroxy-17 -(2-hydroxyacetyl)-1O, 3- dimethyl-l ,2,6,7,8,9,12,14,15,16- decahydrocyclopenta[ a]phenanthrene-3, l l-dione 20 Cyproheptadine I-methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-l (15),3,5,7,9, 11,13-1 heptaenylidene )piperidine 21 Dapoxetine (1S)-N,N-dimethyl-3-naphthalen-l-yloxy-l-phenylpropan-l_amiqe 22 Deflazacort [2-[(1 S,2S,4R,8S,9S, 11S,12S, 13R)-II-hydroxy-6,9, 13-trimethyl-16- oxo-5-oxa-7-azapentacyclo[1 0.8.0.02,9.04, 8.013,18]icosa-6, 14,1r- trien-8-yl]-2-oxoethyl] acetate 23 Desisobutyl- 1-[1-(4-chlorophenyl)cyclobutyl]-N,N-dimethyl-2- I benzylsibutramine phenylethanamine 24 Desmethyl carbodenafil 5-[2-ethoxy-5-( 4-methylpiperazine-l-carbonyl)phenyl]-I-methyl_3_ propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one I 25 Desmethylsibutramine 1-[1-(4-chlorophenyl )cyclo buty I]-N,3 -dimethyl butan-l-amine 1 26 Desmethylsildenafil 5-(2-ethoxy-5-piperazin-l-ylsulfonylphenyl)-I-methyl-3-propyl-6H- pyrazolo[ 4,3-d]pyrimidin-7 -one I 27 Dexamethasone (8S,9R,1 OS,11S,13S,14S,16R,17R)-9-fluoro-l1 ,17-dihYdrOxY-17-i(2- hydroxyacetyl)-1 0,13,16-trimethyl-6,7,8, 11,12,14,15,16- octahydrocyclopenta[ a]phenanthren -3-one 28 Diclofenac [2-[(2,6-dichlorophenyl)amino ]phenyl]acetatic acid 29 Diclofenac Sodium Sodium 2-[(2,6-dichlorophenyl)amino]phel!Yl]acetate I 30 Didesmethylsibutramine 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-l-amine I 31 Dimethylacetildenafil S-[ 5-[2-[ (3S,SR)-3,S-dimethylpiperazin-l-yl]acetyl]-2- ethoxyphenyl]-I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7i one 32 Dithiodesmethylcarboden S-[2-ethoxy-S-( 4-methylpiperazine-l-carbothioyl)phenyl]-I-meth*l_ afil 3-propyl-4H-pyrazolo[ 4,3-d]pyrimidine-7 -thione 33 Doxepin (3E)-3-(6H-benzo[ c][1]benzoxepin-l1-ylidene)-N,N- I dimethylpropan-l-amine 34 Ephedrine ephedrine (1R,2S)-2-(methylamino )-I-phenylpropan-l-01 I alkaloids pseudoephedr (1S,2S)-2-(methylamino )-I-phenylpropan-l-01 ine norephedrine (1S,2R)-2-amino-l-phenylpropan-l-01 I norpseudoeph (1S,2S)-2-amino-1-phenylpropan-l-01 I edrine 35 Fenfluramine N-ethyl-1- [3-(trifluoromethy I)phenyl ]propan- 2-amine 36 Flibanserin 3-[2-[ 4-[3-(trifluoromethyl)phenyl]piperazin-l-yl]ethyl]_1 H- benzimidazol-2-one I 37 FIudrocortisone (8S,9R,IOS,11 S,13S,14S,17R)-9-fluoro-ll,17-dihydroxy-17-(2_ hydroxyacetyl)-1 0, 13-dimethyl-l ,2,6,7,8,11,12,14, IS,16- decahydrocyclopenta[ a]phenanthren- 3-one 38 Fluocinolone (6S,8S,9R, lOS,11S,13S,14S, 16R, 17S)-6,9-difluoro-ll, 16,17- trihydroxy-17-(2-hydroxyacetyl)-1 0, 13-dimethyl-6, 7,8, 11,12,14,15, 16-octahydrocyclopenta[ a]phenanthren- 3-one 39 Fluocinonide [2-[(1 S,2S,4R,8S,9S, 11S,12R, 13S, 19S)-12, 19-difluoro-11-hydroxy- 6,6,9, 13-tetramethyl-16-oxo-S, 7-dioxapentacyclo [10.8.0.02,9.04,8.013, 18]icosa-14, 17-dien-8-yl]-2-oxoethyl] acetate
  • 6. 3 40 Fluorometholone (6S,8S,9R,1 OS,11S,l3S, 14S, 17R)-17-acetyl-9-fluoro-ll, 17- I dihydroxy-6,1 0,13-trimethyl-6, 7,8,11,12,14, 15,16- octahydrocyclopenta[ a]phenanthren -3-one 41 Fluoxetine N-methyl-3-phenyl-3-[ 4-(trifluoromethyl)phenoxy ]propan-l-amine 42 Fluticasone S-(fluoromethyl) (6S,8S,9R,1 OS,11S, 13S, 14S,16R, 17R) -6,9- difluoro-ll, 17-dihydroxy-l 0, 13,16-trimethyl-3-oxo- 6,7,8,11,12,14,15, 16-octahydrocyclopenta[ a] phenanthrene-17- carbothioate 43 Furosemide 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid I 44 Hydrochlorothiazide 6-chloro-l, I-dioxo- 3,4-dihydro- 2H-llambda6,2,4-benzothiadiazire- 7-sulfonamide 45 Hydrocortisone (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17_(2_ hydroxyacetyl)-1 0,l3-dimethyl-2,6, 7,8,9,11,12,14,15, 16-decahydro- 1H-cyclopenta[ a]phenanthren- 3-one I 46 Hydroxyhomosildenafil 5-[2-ethoxy-5-[ 4-(2-hydroxyethyl)piperazin-l-yl]sulfonylphenyl]L 1- methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one 47 Hydroxyacetildenafil 5-[2-ethoxy-5-[2-[ 4-(2-hydroxyethyl)piperazin-l-yl]acetyl] Phen11]- I-methyl-3-propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7 -one 48 Ibuprofen 2-[4-(2-methylpropyl)phenyl]propanoic acid 49 Indomethacin 2-[1-( 4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 50 Ketoprofen 2-(3-benzoylphenyl)propanoic acid 51 Lorcaserin (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-lH-3-benzazepine I 52 Metformin 3-(diaminomethylidene )-1, I-dimethylguanidine 53 Methocarbamol [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate 54 Methylprednisolone (6S,8S,9S,10R,IIS,13S,14S,17R)-11,17-dihydroxy_17_(2_ I hydroxyacetyl)-6, 10,13-trimethyl-7,8,9, 11,12,14,15,16 -octahydr9- 6H-cyclopenta[ a]phenanthren -3-one 55 Mometasone (8S,9R,10S,11 S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)_ 11,17-dihydroxy-l0,13,16-trimethyl-6,7,8, 11,12,14,15,16- octahydrocyclopenta[ a]phenanthren- 3-one 56 Naproxen (2S)-2-( 6-Methoxynaphthalen-2-yl )propanoic acid 57 N-Desmethyl tadalafil (2R,8R)-2-(1 ,3-benzodioxol-5-yl)-3,6, 17-triazatetracyclo [8.7.0.03,8.011, 16]heptadeca-l (10), 11,13, 15-tetraene-4, 7-dione 58 N-Desmethyl-N-benzyl 5-[5-(4-benzylpiperazin-l-yl)sulfonyl-2-ethoxyphenyl]_I_methy1-3- sildenafil propyl-6H-pyrazolo[ 4,3-d]pyrimidin-7-one I 59 N-Desmethylvardenafil 2-[2-ethoxy-5-( 4-methylpiperazin-l-yl)sulfonylphenyl]-5-methyl_7_ propyl-3H-imidazo[ 5,I-f] [1,2,4]triazin-4-one 60 Nefopam 5-methyl-l-phenyl-l ,3,4,6-tetrahydro-2,5-benzoxazocine 61 Orlistat [(2S)-I-[(2S,3 S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2- I formamido-4-methylpentanoate 62 Phenformin 1-(diaminomethylidene )-2-(2-phenylethyl)guanidine 63 Phenytoin 5,5-Diphenylimidazolidine- 2,4-dione 64 Piperadino vardenafil 2-[2-ethoxy-5-(piperidine-l-sulfonyl)-phenyl]-5_methyl-7 -propyl- 3H-imidazo[5, I-f]-[1,2,4]triazin-4- one 65 Piroxicam 4-hydroxy-2-methyl-l, I-dioxo-N-pyridin-2-yl-l1ambda6,2- benzothiazine- 3-carboxamide 66 Prednisolone (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy_17_(2_ I hydroxyacetyl)-1 0, 13-dimethyl-7,8,9, 11,12,14,15, 16-octahydro-6H- cyclopenta[ a]phenanthren-3-one 67 Prednisone (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13- dimethyl-6, 7,8,9,12,14,15, 16-octahydrocyclopenta[ a]Phenanthrener 3,II-dione
  • 7. · . ,'l , r ,> 4 68 Propranolol (2RS)-I-[(Propan-2-yl)amino ]-3-[(naphthalen-l- yl)oxy]propan-2-o1 I 69 Salbutamol (lRS)-2-[(I, I-Dimethylethyl)amino ]-1-[ 4-hYdrOxY-3t (hydroxymethyl)phenyl]ethanol 70 Salmeterol 2-(hydroxymethyl)-4-[I-hydroxy-2-[6_( 4- J phenylbutoxy)hexylamino ]ethyl]phenol 71 Sildenafil S-[2-ethoxy-S-( 4-methylpiperazin-l- I yl)sulfonylphenyl]-I-methyl-3-propyl-6H_ pyrazolo[ 4,3-d]pyrimidin-7 -one I 72 Sulfoaildenafil S-[S-[(3S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl_2_1 ethoxyphenyl]-I-methyl-3-propyl-4H-pyrazolo[ 4,3- d]pyrimidine-7 -thione 73 Sulfohydroxyhomosildenafil S-[2-ethoxy-S-[ 4-(2-hydroxyethyl)piperazin-l- I yl]sulfonylphenyl]-I-methyl-3-propyl-4H_ pyrazolo[ 4,3-d]pyrimidine-7 -thione 74 Tadalafil (6R, 12aR)-6-(1 ,3-Benzodioxol-S-yl)-2-methyl- 2,3,6,7,12, 12a-hexahydropyrazino[I',2': 1,6]- I pyrido[3,4-b ]indole-l ,4-dione 7S Terazosin hydrochloride 1-(4-Amino-6, 7-dimethoxyquinazolin-2-yl)-4- [[(2RS)-tetrahydrofuran-2-yl]carbonyl]piperazine i hydrochloride 76 Testosterone (8R,9S,1 OR,13S,14S,17S)-17-hydroxy-l 0,13- dimethyl-l ,2,6,7,8,9, 11,12,14, IS, 16,17- dodecahydrocyclopenta[ a]phenanthren- 3-one 77 Thioaidenafil S-[S-[(3 S,SR)-3,S-dimethylpiperazin-l-yl]sulfonyl_2_ ethoxyphenyl]-I-methyl-3-propyl-6H-pyrazolo[ 4,3- d]pyrimidine-7 -thione I 78 Thiosildenafil S-[2-ethoxy-S-( 4-methylpiperazin-l- I yl)sulfonylphenyl]-I-methyl-3-propyl_6H_ pyrazolo[ 4,3-d]pyrimidine-7 -thione 79 Triamcinolone 9a -Fluoro-ll~,16a,17a,21-tetrahydroxypregna_l ,4- I diene-3,20-dione 80 Vardenafil 1-{[3-(3,4-Dihydro-S-methyl-4-oxo-7- propylimidazo[S,I-fJ-as-triazin-2-yl)-4_ ethoxyphenyl] sulfonyl }-4-ethylpiperazine Truong Qu8e Cmyng