Worldwide pharmaceutical sales are projected to increase at a compound annual growth rate of 5-8% reaching $1.1 trillion by 2014, fueled by double-digit growth in emerging economies. However, many large firms face challenges as drug patents expire and revenues could drop by 30-40%. The US generics market is anticipated to grow 10% annually through 2013 due to healthcare reforms that will provide insurance to 32 million more people and the establishment of a regulatory pathway for biosimilars. Progressive pharmaceutical companies must adopt new workforce strategies to respond to these pressures and opportunities in the changing marketplace.