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The Right Way to Build
Predictive Models for the Most
Vulnerable Patient Populations
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
This article is based on a 2020 Healthcare Analytics Summit (HAS 20 Virtual)
presentation titled “Machine Learning, Social Determinants, and Data Selection
for Population Health” by Terri H Steinberg, MD, MBA, FACP, Chief Health
Information Officer, Vice President for Population Health Informatics,
ChrisitanaCare, and Jason Jones, PhD, Chief Data Scientist, Health Catalyst.
The Right Way to Build Predictive Models
Terri H. Steinberg, MD, MBA, FACP
Chief Health Information Officer,
VP for Population Health Informatics,
ChrisitanaCare
Jason Jones, PhD
Chief Data Scientist,
Health Catalyst
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Right Way to Build Predictive Models
The use of artificial intelligence (AI) and,
specifically, predictive models to identify the
most vulnerable patient populations is a
strategic approach to managing population
health initiatives.
By sorting patients based on risk level and
identifying clusters of need, health system
team members can perform outreach and
interventions to maximize the quality of patient
care and the predictive model’s effectiveness.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Right Way to Build Predictive Models
Building a successful model requires the
right technology stack, human oversight
and intervention, and most importantly,
quality data to fuel the machine.
Disparities in data collection, the type of
data sources available, and limited
interoperability between systems can make
the data component the most challenging
and time-consuming piece of the AI puzzle.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Right Way to Build Predictive Models
Putting the upfront time and resources into
managing and understanding available data
allows organizations to more easily
build predictive AI models to support
their population health efforts.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Determining Data Sources for Maximum Predictability
Organizations have access to hundreds, if
not thousands, of data points from various
sources—EMRs, Health Information
Exchanges (HIEs), claims, social
determinants of health, etc.—and these
sources often have overlapping data.
Thoroughly understanding the desired model
and outcome allows team members to zero
in on the best data sources to utilize.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Determining Data Sources for Maximum Predictability
It’s important to note that more is not
always better, as overwhelming the model
with unnecessary data points can lead to
confusion and difficulty in maintenance.
The goal should be to build the simplest
model possible with the maximum
predictive power.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Determining Data Sources for Maximum Predictability
Building the model itself is fairly simple when
compared to the data management component.
Therefore, data scientists should avoid forcing a
model built and used for one organization to
work elsewhere.
Patient populations, data collection practices,
data sources and more can vary widely from one
health system to another, rendering a “recycled”
model useless in a new environment.
Data users at each organization must determine
their type of data, source, and desired outcome.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Technology Needs for Predictive Models
Both the input and output of data for a predictive
AI model require certain technology.
In addition to platforms used internally by health
systems, integrated patient tools, such as
member portals and biometric devices, can
provide meaningful data to help segment
populations that may be at risk for poor outcomes.
Population health EMRs optimized to provide AI-
generated recommendations directly into existing
workflows create a seamless experience and
allow team members to provide more timely care.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Technology Needs for Predictive Models
On the backend, a data and analytics platform
that can aggregate data from all sources is
another must-have in the technology stack.
A robust data platform can perform business
logic and make it actionable, provide visually
appealing dashboards to understand financial
and clinical performance, and perform important
predictions for population health management.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Technology Needs for Predictive Models
Lastly, an interoperability platform that
allows information to flow freely between
systems is essential.
For example, an open platform like the
Health Catalyst Data Operating System
(DOSÔ) enables health systems to
extract data from various source systems
and aggregate disparate data sets using
healthcare-specific terminology.
The result is powerful analytics and
insights that support predictive models.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Human Oversight for Informed Interventions
While machines are great at recognizing patterns
and running calculations, they don’t take the
place of reasoning, logic, and interventions that
team members must perform.
Human oversight and input are critical in
determining data sets and resources available
and defining the appropriate outreach or
intervention for each outcome or patient
population.
The machine’s output doesn’t necessarily
determine the next steps—it merely allows for
more informed risk stratification and identifies
opportunities for patient engagement.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Perfect Predictive Model for Population Health
Surprisingly, a successful predictive
AI model will appear to degrade
over time.
A newly launched model may
identify large patient populations as
being at-risk.
But, over time, when paired with an
effective intervention, that model
will appear incorrect.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Perfect Predictive Model for Population Health
For example, a model may say that a
patient is at risk for hospital readmission.
In response, the care team puts the
appropriate intervention in place and
prevents the readmission.
Suddenly, it looks as if the model is
wrong because the patient wasn’t
actually readmitted.
When this disconnect occurs, predictive
model users need to capture what the
interventions are and understand why
performance is going down.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Perfect Predictive Model for Population Health
Machines can help separate whether the
low performance results from poor
predictability due to data or risk level
changing, or whether it is due to a correctly
implemented intervention.
If the latter is true, then the team has
created a successful model.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
The Right Combination of Data,
Technology, and Skillset
Building successful predictive models for
population health requires the right
combination of data, technology, and
human intervention.
The journey requires continual learning,
understanding the data fueling the
outcomes, and optimizing models and
interventions for the most predictive
performance and best quality of care.
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
For more information:
“This book is a fantastic piece of work”
– Robert Lindeman MD, FAAP, Chief Physician Quality Officer
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
More about this topic
Link to original article for a more in-depth discussion.
The Right Way to Build Predictive Models for the Most Vulnerable Patient Populations
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© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Terri Steinberg, M.D., M.B.A., FACP is the Chief Health Information Officer and Vice
President of Population Health Informatics at Christiana Care Health System, a large
multi-entity healthcare organization in Delaware. Dr. Steinberg has lectured and
consulted extensively on methods to ensure successful technology adoption by
physicians and nurses, on the positive impact of technology on safe medication practice,
and on the use of technology to drive Population Health management. As a clinician as
well as a software developer, Dr. Steinberg has used her experience to guide the optimal
implementation of clinical systems in a manner that is well-accepted by doctors and nurses. Dr.
Steinberg currently devotes much of her time to population health IT, to provide innovative technology
services to Christiana Care Health System’s care management company, CareLink Care Now.
Other Clinical Quality Improvement Resources
Click to read additional information at www.healthcatalyst.com
Terri H. Steinberg, MD, MBA, FACP
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Jason Jones currently serves as Chief Data Scientist at Health Catalyst. Previously, he
served at Kaiser Permanente (KP) in various roles including Research Scientist and VP,
Information Support for Care Transformation. Prior to KP, Jones was a Medical
Informaticist for Intermountain Healthcare. Other roles have included analytic and
marketing leadership positions at Bayer HealthCare, data and information product
development at UnitedHealth Group, and various academic adjunct faculty positions.
Jones received his PhD in Biostatistics from the University of Southern California in
2001. His mission is to leverage data to achieve the Quadruple Aim.
Other Clinical Quality Improvement Resources
Click to read additional information at www.healthcatalyst.com
Jason Jones, PhD
© 2021 Health Catalyst
Proprietary. Feel free to share but we would appreciate a Health Catalyst citation.
Other Clinical Quality Improvement Resources
Click to read additional information at www.healthcatalyst.com
Health Catalyst is a mission-driven data warehousing, analytics and outcomes-improvement
company that helps healthcare organizations of all sizes improve clinical, financial, and operational
outcomes needed to improve population health and accountable care. Our proven enterprise data
warehouse (EDW) and analytics platform helps improve quality, add efficiency and lower costs in
support of more than 65 million patients for organizations ranging from the largest US health system
to forward-thinking physician practices.
Health Catalyst was recently named as the leader in the enterprise healthcare BI market in
improvement by KLAS, and has received numerous best-place-to work awards including Modern
Healthcare in 2013, 2014, and 2015, as well as other recognitions such as “Best Place to work for
Millenials, and a “Best Perks for Women.”

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The Right Way to Build Predictive Models for the Most Vulnerable Patient Populations

  • 1. The Right Way to Build Predictive Models for the Most Vulnerable Patient Populations
  • 2. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. This article is based on a 2020 Healthcare Analytics Summit (HAS 20 Virtual) presentation titled “Machine Learning, Social Determinants, and Data Selection for Population Health” by Terri H Steinberg, MD, MBA, FACP, Chief Health Information Officer, Vice President for Population Health Informatics, ChrisitanaCare, and Jason Jones, PhD, Chief Data Scientist, Health Catalyst. The Right Way to Build Predictive Models Terri H. Steinberg, MD, MBA, FACP Chief Health Information Officer, VP for Population Health Informatics, ChrisitanaCare Jason Jones, PhD Chief Data Scientist, Health Catalyst
  • 3. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Right Way to Build Predictive Models The use of artificial intelligence (AI) and, specifically, predictive models to identify the most vulnerable patient populations is a strategic approach to managing population health initiatives. By sorting patients based on risk level and identifying clusters of need, health system team members can perform outreach and interventions to maximize the quality of patient care and the predictive model’s effectiveness.
  • 4. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Right Way to Build Predictive Models Building a successful model requires the right technology stack, human oversight and intervention, and most importantly, quality data to fuel the machine. Disparities in data collection, the type of data sources available, and limited interoperability between systems can make the data component the most challenging and time-consuming piece of the AI puzzle.
  • 5. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Right Way to Build Predictive Models Putting the upfront time and resources into managing and understanding available data allows organizations to more easily build predictive AI models to support their population health efforts.
  • 6. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Determining Data Sources for Maximum Predictability Organizations have access to hundreds, if not thousands, of data points from various sources—EMRs, Health Information Exchanges (HIEs), claims, social determinants of health, etc.—and these sources often have overlapping data. Thoroughly understanding the desired model and outcome allows team members to zero in on the best data sources to utilize.
  • 7. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Determining Data Sources for Maximum Predictability It’s important to note that more is not always better, as overwhelming the model with unnecessary data points can lead to confusion and difficulty in maintenance. The goal should be to build the simplest model possible with the maximum predictive power.
  • 8. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Determining Data Sources for Maximum Predictability Building the model itself is fairly simple when compared to the data management component. Therefore, data scientists should avoid forcing a model built and used for one organization to work elsewhere. Patient populations, data collection practices, data sources and more can vary widely from one health system to another, rendering a “recycled” model useless in a new environment. Data users at each organization must determine their type of data, source, and desired outcome.
  • 9. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Technology Needs for Predictive Models Both the input and output of data for a predictive AI model require certain technology. In addition to platforms used internally by health systems, integrated patient tools, such as member portals and biometric devices, can provide meaningful data to help segment populations that may be at risk for poor outcomes. Population health EMRs optimized to provide AI- generated recommendations directly into existing workflows create a seamless experience and allow team members to provide more timely care.
  • 10. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Technology Needs for Predictive Models On the backend, a data and analytics platform that can aggregate data from all sources is another must-have in the technology stack. A robust data platform can perform business logic and make it actionable, provide visually appealing dashboards to understand financial and clinical performance, and perform important predictions for population health management.
  • 11. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Technology Needs for Predictive Models Lastly, an interoperability platform that allows information to flow freely between systems is essential. For example, an open platform like the Health Catalyst Data Operating System (DOSÔ) enables health systems to extract data from various source systems and aggregate disparate data sets using healthcare-specific terminology. The result is powerful analytics and insights that support predictive models.
  • 12. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Human Oversight for Informed Interventions While machines are great at recognizing patterns and running calculations, they don’t take the place of reasoning, logic, and interventions that team members must perform. Human oversight and input are critical in determining data sets and resources available and defining the appropriate outreach or intervention for each outcome or patient population. The machine’s output doesn’t necessarily determine the next steps—it merely allows for more informed risk stratification and identifies opportunities for patient engagement.
  • 13. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Perfect Predictive Model for Population Health Surprisingly, a successful predictive AI model will appear to degrade over time. A newly launched model may identify large patient populations as being at-risk. But, over time, when paired with an effective intervention, that model will appear incorrect.
  • 14. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Perfect Predictive Model for Population Health For example, a model may say that a patient is at risk for hospital readmission. In response, the care team puts the appropriate intervention in place and prevents the readmission. Suddenly, it looks as if the model is wrong because the patient wasn’t actually readmitted. When this disconnect occurs, predictive model users need to capture what the interventions are and understand why performance is going down.
  • 15. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Perfect Predictive Model for Population Health Machines can help separate whether the low performance results from poor predictability due to data or risk level changing, or whether it is due to a correctly implemented intervention. If the latter is true, then the team has created a successful model.
  • 16. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. The Right Combination of Data, Technology, and Skillset Building successful predictive models for population health requires the right combination of data, technology, and human intervention. The journey requires continual learning, understanding the data fueling the outcomes, and optimizing models and interventions for the most predictive performance and best quality of care.
  • 17. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. For more information: “This book is a fantastic piece of work” – Robert Lindeman MD, FAAP, Chief Physician Quality Officer
  • 18. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. More about this topic Link to original article for a more in-depth discussion. The Right Way to Build Predictive Models for the Most Vulnerable Patient Populations Artificial Intelligence and Machine Learning in Healthcare: Four Real-World Improvements Health Catalyst Editors Three Keys to Improving Hospital Patient Flow with Machine Learning Health Catalyst Editors AI in Healthcare: Finding the Right Answers Faster Health Catalyst Editors Machine Learning Tools Unlock the Most Critical Insights from Unstructured Health Data Health Catalyst Editors Safeguarding the Ethics of AI in Healthcare: Three Best Practices Health Catalyst Editors
  • 19. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Terri Steinberg, M.D., M.B.A., FACP is the Chief Health Information Officer and Vice President of Population Health Informatics at Christiana Care Health System, a large multi-entity healthcare organization in Delaware. Dr. Steinberg has lectured and consulted extensively on methods to ensure successful technology adoption by physicians and nurses, on the positive impact of technology on safe medication practice, and on the use of technology to drive Population Health management. As a clinician as well as a software developer, Dr. Steinberg has used her experience to guide the optimal implementation of clinical systems in a manner that is well-accepted by doctors and nurses. Dr. Steinberg currently devotes much of her time to population health IT, to provide innovative technology services to Christiana Care Health System’s care management company, CareLink Care Now. Other Clinical Quality Improvement Resources Click to read additional information at www.healthcatalyst.com Terri H. Steinberg, MD, MBA, FACP
  • 20. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Jason Jones currently serves as Chief Data Scientist at Health Catalyst. Previously, he served at Kaiser Permanente (KP) in various roles including Research Scientist and VP, Information Support for Care Transformation. Prior to KP, Jones was a Medical Informaticist for Intermountain Healthcare. Other roles have included analytic and marketing leadership positions at Bayer HealthCare, data and information product development at UnitedHealth Group, and various academic adjunct faculty positions. Jones received his PhD in Biostatistics from the University of Southern California in 2001. His mission is to leverage data to achieve the Quadruple Aim. Other Clinical Quality Improvement Resources Click to read additional information at www.healthcatalyst.com Jason Jones, PhD
  • 21. © 2021 Health Catalyst Proprietary. Feel free to share but we would appreciate a Health Catalyst citation. Other Clinical Quality Improvement Resources Click to read additional information at www.healthcatalyst.com Health Catalyst is a mission-driven data warehousing, analytics and outcomes-improvement company that helps healthcare organizations of all sizes improve clinical, financial, and operational outcomes needed to improve population health and accountable care. Our proven enterprise data warehouse (EDW) and analytics platform helps improve quality, add efficiency and lower costs in support of more than 65 million patients for organizations ranging from the largest US health system to forward-thinking physician practices. Health Catalyst was recently named as the leader in the enterprise healthcare BI market in improvement by KLAS, and has received numerous best-place-to work awards including Modern Healthcare in 2013, 2014, and 2015, as well as other recognitions such as “Best Place to work for Millenials, and a “Best Perks for Women.”