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The plasma membrane is made of phospholipids. A phospholipid molecule has a polar head and
two non-polar tails. How does the plasma membrane work? Polar molecules can interact with the
polar heads and cross the membrane. Polar molecules form covalent bands with the polar heads
and become permanently attached to them. Polar molecules are excluded from the interior of the
membrane by repulsion from non-polar tails: Non polar molecules are excluded from the interior
of the membrane by repulsion from non-polar tails. Non-polar molecules are attracted to the non-
polar tails, thus not being able to cross the membrane.

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