The document discusses texture analyzers, instruments used to measure the textural properties of materials in pharmaceutical contexts. It outlines their principle of operation, which involves measuring material responses to controlled forces to determine attributes like firmness and elasticity. Applications include evaluating oral dosage forms, assessing mucoadhesion for drug delivery systems, and mechanical characterization of pharmaceutical materials.

1. NOVEL DRUG
DELIVERY SYSTEMS
Presented by
Preetham Anton A
B. Pharm VIth Semester
Texture Analyzer

2. • A texture analyzer is an analytical instrument
used to measure the textural properties of
materials, such as,
Firmness Cohesiveness Elasticity
Adhesiveness
• It typically involves applying a controlled
force to the material and measuring its
response.
What is Texture Analyzer?

3. TEXT PLUS TEXTURE
ANALYZER

4. Key Mechanism
Applied control force using arm
probe
Measure material
response
Calculate textural
properties
Principle
A texture analyzer operates on the principle of
measuring how a material reacts to forces
such as compression, stretching, or bending, to
determine textural properties like hardness and
elasticity.

5. Applications
Mechanical
characterization of
pharmaceutical materials
Estimating
disintegration time
of oral dosage forms
Evaluating textural
properties like hardness
and cohesiveness
Mucoadhesion
testing for drug
delivery systems
Assessing in vivo
characteristics of oral
medications

7. Reference
1. Smewing J. Texture analysis for evaluating the quality of pharmaceutical
products. PHARMAZEUTISCHE INDUSTRIE. 2000 Jul 1;62(7):556-8
2. Plummer, K. (2024). Texture Analysers. In: Rosenthal, A., Chen, J. (eds)
Food Texturology: Measurement and Perception of Food Textural
Properties. Springer, Cham. https://doi.org/10.1007/978-3-031-41900-3_9
3. Rahman, M.S., Al-Attabi, Z.H., Al-Habsi, N., Al-Khusaibi, M. (2021).
Measurement of Instrumental Texture Profile Analysis (TPA) of Foods. In:
Khan, M.S., Shafiur Rahman, M. (eds) Techniques to Measure Food Safety
and Quality. Springer, Cham. https://doi.org/10.1007/978-3-030-68636-9_17
4. Bogdan C, Hales D, Cornilă A, Casian T, Iovanov R, Tomu ă I, Iurian S.
ț
Texture analysis–a versatile tool for pharmaceutical evaluation of solid oral
dosage forms. International Journal of Pharmaceutics. 2023 May
10;638:122916.