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GGeerroonnttoollooggiiccaall NNuurrssiinngg 
THIRD EDITION 
CHAPTER 
6 
Pharmacology and 
Older Adults 
Copyright © 2014, © 2010, © 2006 by Pearson Education, Inc. 
All Rights Reserved
Learning Objectives 
1. Explain the interaction between 
normal aging and responses to drug 
therapy in older people. 
2. Identify principles of safe medication 
management with older persons in a 
variety of patient care settings. 
3. Discuss measures to prevent and 
reduce polypharmacy in older patients. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Learning Objectives 
4. Describe assessments to monitor older 
patients for adverse drug effects and 
polypharmacy. 
5. Apply principles of teaching and 
learning to promote compliance and 
adherence to the medication regimen. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Learning Objectives 
6. List nonpharmacological therapies that 
may be useful as alternatives to 
medications. 
7. Discuss issues related to ensuring the 
safe use drug therapy by the older 
person. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Introduction 
• Drug therapy in the older person 
presents many challenges in ensuring 
the appropriate use of medications. 
• The nurse is in a pivotal position to use 
nursing assessments and nursing 
interventions to promote the 
appropriate use of medications. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Cultural Diversity and Medication 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski 
Use 
• Cultural diversity and ethnic 
background can affect the older 
person’s beliefs about health, illness, 
medications, and physiological 
response to medications.
Pharmacodynamic Alterations 
• In addition to the alterations due to 
normal aging processes, older persons 
are more likely to have chronic 
pathological conditions that may affect 
responses to drugs. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Box 6-1 Definitions of Adverse Drug Reactions and Adverse Drug Events 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Adverse Drug Events of Concern in 
Older Persons 
• Side effects including amnesia, 
depression, nausea, vomiting, lethargy, 
confusion, and visual disturbances 
occur more often in older persons than 
in younger patients. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Box 6-2 Heuristic for Remembering Anticholinergic Effects 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Box 6-4 Warning Signs of NSAID-Induced Gastric Irritation 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Adverse Effects of Interactions 
• When multiple medications are used, 
there is a greater chance of drug-drug 
interactions, ADEs, and ADRs. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Promoting Medication 
Effectiveness and Safety 
• The nurse has a pivotal role in ensuring 
that a person’s drug therapy is both 
effective for the person’s condition and 
to prevent, detect, or to intervene as 
early as possible if the person develops 
adverse drug effects. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Promoting Medication 
Effectiveness and Safety 
• The “five rights” of medication 
administration: 
–Right patient 
–Right drug 
–Right dose 
–Right route 
–Right time 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Potentially Inappropriate Drugs 
• Some drugs are considered to be 
inappropriate to use for older persons 
because of their adverse effects. 
• “Beers list” 
• The nurse can use the list as a basis of 
questioning the prescribing clinician 
about the appropriateness of a drug 
being used in a particular patient. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Appropriate Use of Psychotropics 
• The use of psychotropic drugs in older 
persons, especially those in institutional 
settings, is of concern due to potential 
use of these drugs for less than optimal 
therapeutic reasons. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Medication Management 
• The nurse has a major role in 
promoting the safe and effective 
management of medications. 
• This includes the correct storage, 
preparation, and administration. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Medication Management 
• The nurse can be instrumental in 
promoting compliance and appropriate 
management of drug therapy by older 
patients or their caregivers in the 
home. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Assessing Older Patients’ 
Appropriate Use of Medications 
• Assessment of drug effects is a nursing 
responsibility. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Financial Considerations in 
Medication Use 
• Financial pressures may result in 
people taking dangerous actions related 
to prescription drugs. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Medicare Part D 
• Medicare part D went into effect and 
has assisted many with their drug 
costs. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski
Patient and Family Teaching 
• Educating patients and families is 
critical so that nurses can interpret 
scientific data and individualize the 
nursing care plan. 
Gerontological Nursing, Third Edition 
Patricia A. Tabloski

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Tabloski ch06 lecture

  • 1. GGeerroonnttoollooggiiccaall NNuurrssiinngg THIRD EDITION CHAPTER 6 Pharmacology and Older Adults Copyright © 2014, © 2010, © 2006 by Pearson Education, Inc. All Rights Reserved
  • 2. Learning Objectives 1. Explain the interaction between normal aging and responses to drug therapy in older people. 2. Identify principles of safe medication management with older persons in a variety of patient care settings. 3. Discuss measures to prevent and reduce polypharmacy in older patients. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 3. Learning Objectives 4. Describe assessments to monitor older patients for adverse drug effects and polypharmacy. 5. Apply principles of teaching and learning to promote compliance and adherence to the medication regimen. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 4. Learning Objectives 6. List nonpharmacological therapies that may be useful as alternatives to medications. 7. Discuss issues related to ensuring the safe use drug therapy by the older person. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 5. Introduction • Drug therapy in the older person presents many challenges in ensuring the appropriate use of medications. • The nurse is in a pivotal position to use nursing assessments and nursing interventions to promote the appropriate use of medications. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 6. Cultural Diversity and Medication Gerontological Nursing, Third Edition Patricia A. Tabloski Use • Cultural diversity and ethnic background can affect the older person’s beliefs about health, illness, medications, and physiological response to medications.
  • 7. Pharmacodynamic Alterations • In addition to the alterations due to normal aging processes, older persons are more likely to have chronic pathological conditions that may affect responses to drugs. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 8. Box 6-1 Definitions of Adverse Drug Reactions and Adverse Drug Events Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 9. Adverse Drug Events of Concern in Older Persons • Side effects including amnesia, depression, nausea, vomiting, lethargy, confusion, and visual disturbances occur more often in older persons than in younger patients. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 10. Box 6-2 Heuristic for Remembering Anticholinergic Effects Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 11. Box 6-4 Warning Signs of NSAID-Induced Gastric Irritation Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 12. Adverse Effects of Interactions • When multiple medications are used, there is a greater chance of drug-drug interactions, ADEs, and ADRs. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 13. Promoting Medication Effectiveness and Safety • The nurse has a pivotal role in ensuring that a person’s drug therapy is both effective for the person’s condition and to prevent, detect, or to intervene as early as possible if the person develops adverse drug effects. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 14. Promoting Medication Effectiveness and Safety • The “five rights” of medication administration: –Right patient –Right drug –Right dose –Right route –Right time Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 15. Potentially Inappropriate Drugs • Some drugs are considered to be inappropriate to use for older persons because of their adverse effects. • “Beers list” • The nurse can use the list as a basis of questioning the prescribing clinician about the appropriateness of a drug being used in a particular patient. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 16. Appropriate Use of Psychotropics • The use of psychotropic drugs in older persons, especially those in institutional settings, is of concern due to potential use of these drugs for less than optimal therapeutic reasons. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 17. Medication Management • The nurse has a major role in promoting the safe and effective management of medications. • This includes the correct storage, preparation, and administration. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 18. Medication Management • The nurse can be instrumental in promoting compliance and appropriate management of drug therapy by older patients or their caregivers in the home. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 19. Assessing Older Patients’ Appropriate Use of Medications • Assessment of drug effects is a nursing responsibility. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 20. Financial Considerations in Medication Use • Financial pressures may result in people taking dangerous actions related to prescription drugs. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 21. Medicare Part D • Medicare part D went into effect and has assisted many with their drug costs. Gerontological Nursing, Third Edition Patricia A. Tabloski
  • 22. Patient and Family Teaching • Educating patients and families is critical so that nurses can interpret scientific data and individualize the nursing care plan. Gerontological Nursing, Third Edition Patricia A. Tabloski