This document provides a project proposal for systems biology research at NIPER. It outlines an academic program involving systems biology courses for biotechnology students and research projects on targets for lifestyle diseases like oxidative stress and aging as well as communicable diseases. The proposal describes procuring hardware, software, and equipment needed for the research. It presents a workflow for systems biology moving from omics data to target identification using both wet lab and in silico methods along with the relevant software tools.
Feature story from the Garvan Institute of Medical Research's December 2012 issue of Breakthrough newsletter. More at https://www.garvan.org.au/news-events/newsletters
The document discusses project planning and control. It covers what a project plan is, who is responsible for planning, and the benefits of planning. It then describes the key elements of a plan and the four-stage planning process: 1) defining scope and responsibilities, 2) scheduling and time/resource analysis, 3) cost estimating and budgeting, and 4) risk analysis and response planning. The objectives of monitoring and control are also covered.
This document appears to be an architectural floor plan with dimensions and labels for various rooms and features. The summary is:
- The floor plan shows dimensions for an overall structure that is approximately 90' wide by 75' long.
- It contains labels for various rooms like bedrooms, bathrooms, kitchen, living areas, and outdoor areas like a pool and decks.
- Precise dimensions are provided for walls, doors, windows, and other architectural elements throughout the floor plan.
- Fusion operational uptime and MTBF were lower in Q1-Q2 2005 than target levels due to factory power shutdowns and production issues. MTTR was also higher in some months.
- LTX pre-ship hit rate was 100% in Q1-Q2 2005, while PSK repair turnaround time averaged around 10 days.
- The top five failures in Q1-Q2 2005 were related to PECHF and SMS_DIG components.
This document is a floor plan showing the layout of a typical floor (Block "A") that includes 8 residential units. Each unit includes between 1-3 bedrooms, a living/dining area, kitchen, and bathroom(s). The units range in size from approximately 1,000-1,300 square feet. The floor plan demonstrates the placement of rooms, doors, windows, and balconies within each unit and how they relate to one another.
Jari Takatalo is a visiting scholar at the H-STAR Institute. The document discusses emerging learning technologies like MOOCs, VR, and learning analytics. It also discusses psychologically-based experiences in entertainment virtual environments and the concepts of physical and social presence, attention, arousal, flow, and outcomes like enjoyment. A graph shows results from an XR playtest on metrics like presence, involvement, flow, and emotional response. The conclusion emphasizes understanding your game and gamer for success.
Feature story from the Garvan Institute of Medical Research's December 2012 issue of Breakthrough newsletter. More at https://www.garvan.org.au/news-events/newsletters
The document discusses project planning and control. It covers what a project plan is, who is responsible for planning, and the benefits of planning. It then describes the key elements of a plan and the four-stage planning process: 1) defining scope and responsibilities, 2) scheduling and time/resource analysis, 3) cost estimating and budgeting, and 4) risk analysis and response planning. The objectives of monitoring and control are also covered.
This document appears to be an architectural floor plan with dimensions and labels for various rooms and features. The summary is:
- The floor plan shows dimensions for an overall structure that is approximately 90' wide by 75' long.
- It contains labels for various rooms like bedrooms, bathrooms, kitchen, living areas, and outdoor areas like a pool and decks.
- Precise dimensions are provided for walls, doors, windows, and other architectural elements throughout the floor plan.
- Fusion operational uptime and MTBF were lower in Q1-Q2 2005 than target levels due to factory power shutdowns and production issues. MTTR was also higher in some months.
- LTX pre-ship hit rate was 100% in Q1-Q2 2005, while PSK repair turnaround time averaged around 10 days.
- The top five failures in Q1-Q2 2005 were related to PECHF and SMS_DIG components.
This document is a floor plan showing the layout of a typical floor (Block "A") that includes 8 residential units. Each unit includes between 1-3 bedrooms, a living/dining area, kitchen, and bathroom(s). The units range in size from approximately 1,000-1,300 square feet. The floor plan demonstrates the placement of rooms, doors, windows, and balconies within each unit and how they relate to one another.
Jari Takatalo is a visiting scholar at the H-STAR Institute. The document discusses emerging learning technologies like MOOCs, VR, and learning analytics. It also discusses psychologically-based experiences in entertainment virtual environments and the concepts of physical and social presence, attention, arousal, flow, and outcomes like enjoyment. A graph shows results from an XR playtest on metrics like presence, involvement, flow, and emotional response. The conclusion emphasizes understanding your game and gamer for success.
The document is a floor plan for the first level of a house. It includes dimensions and labels for various rooms of the house such as the living room, kitchen, dining room, garage, and others. The plan shows the overall layout of the first floor and placement of rooms. Key elements like windows, doors, and fixtures are indicated on the plan.
This document analyzes test score and poverty rate data from schools in CESA 3 to identify schools that may be "beating the odds". It ranks schools based on their free/reduced lunch counts and their percentages of students scoring advanced on math tests. Subtracting these ranks identifies schools with higher than expected test scores given their poverty levels. The document provides these rankings for each grade level and school-wide to help identify programs from schools that are exceeding expectations. It notes this is not a scientific analysis but may provide useful information for planning or program comparisons.
T2 Partners Presentation On The Mortgage Crisismdjonesb
This 3 paragraph document provides an overview of the housing/credit crisis and why there is more pain to come:
1) Housing was stable for the second half of the 20th century but then prices exploded from 2000-2006 as lending standards declined dramatically, allowing homeowners to borrow much more against their homes.
2) As a result, the percentage of equity homeowners had in their homes fell below 50% for the first time, leaving many underwater. Private label mortgages like subprime, which were securitized by Wall Street, made up only 15% of mortgages but account for 51% of seriously delinquent loans.
3) Deregulation led to a surge in profits and compensation
1) The document contains musical notation for a jazz solo over the chord progression of Lester's Blues.
2) It is a solo performed by Dave Cliff on tenor saxophone.
3) The solo contains improvised lines over the standard 12-bar blues form, moving through the chord changes of G7, C7, and E7.
1. The document shows a floor plan with dimensions for a 63' by 24'8" commercial building space.
2. The floor plan details stairwell dimensions from the first to second floor, including 20 risers at 7" and 18 treads at 11".
3. Various room dimensions are indicated, including a 20' by 20' room labeled as "Shipping and Receiving".
Maria First Floor Reflectedceiling Planmariacadtech
1. The document is a reflected ceiling plan that shows the layout of the ceiling and lighting for the first floor of a commercial building.
2. It includes a legend defining the ceiling materials used, which are 2'x4' and 2'x2' acoustical panels suspended from a grid system.
3. Notes provide specifications for the ceiling suspension system, acoustical panels, installation requirements, and ceiling heights throughout the building.
T2 Partners Presentation On The Mortgage Crisisrossreller
This document provides an overview of the housing and credit crisis and why more problems are expected. It summarizes that loose lending standards from 2001-2006 led to a surge in risky mortgages. When home prices stopped rising rapidly in 2006-2007, these risky loans began defaulting in large numbers, especially the private label securities not backed by Fannie Mae or Freddie Mac. The crisis was caused by a combination of factors including loose lending, excessive risk taking on Wall Street to generate profits, and a belief that home prices would keep rising indefinitely. More defaults are expected as problem loans continue working their way through the system.
Purdue Me State Of The School June 2009lauramedwards
The document provides an overview of the School of Mechanical Engineering from June 2009. It discusses the people, learning, discovery, rankings, and development areas of the school. Key points include new faculty being added, undergraduate and graduate enrollment reaching all-time highs, high research expenditures and awards, strong US News rankings, and over $14 million raised for development in 2007-08.
This document contains sheet music for the folk song "Pretty Girl Milkin' Her Cow - Jig" arranged for ukulele. The sheet music displays the melody and chords using standard musical notation. It includes four verses of the song along with chord indications above the staff. A short description at the bottom provides attribution and copyright information for the sheet music.
Graph 1 matches Table 1 and the equation y = 3x + 2.
Graph 2 matches Table 2 and the equation y = 2x + 1.
Graph 3 matches Table 3 and the equation y = 1/2x + 1.
This document shows growth charts for weight and length in boys from birth to 6 months. The charts display percentiles for weight and length by age. They indicate average growth as well as ranges above and below average.
This document shows growth charts for boys from birth to 2 years of age. The charts track weight-for-age and length-for-age percentiles. Weight and length are plotted on the y-axis against age in months on the x-axis. The charts include reference percentiles of 3rd, 15th, 50th, 85th, and 97th to assess whether a child's growth matches what is typical.
The document is a floor plan for the first level of a house. It includes dimensions and labels for various rooms of the house such as the living room, kitchen, dining room, garage, and others. The plan shows the overall layout of the first floor and placement of rooms. Key elements like windows, doors, and fixtures are indicated on the plan.
This document analyzes test score and poverty rate data from schools in CESA 3 to identify schools that may be "beating the odds". It ranks schools based on their free/reduced lunch counts and their percentages of students scoring advanced on math tests. Subtracting these ranks identifies schools with higher than expected test scores given their poverty levels. The document provides these rankings for each grade level and school-wide to help identify programs from schools that are exceeding expectations. It notes this is not a scientific analysis but may provide useful information for planning or program comparisons.
T2 Partners Presentation On The Mortgage Crisismdjonesb
This 3 paragraph document provides an overview of the housing/credit crisis and why there is more pain to come:
1) Housing was stable for the second half of the 20th century but then prices exploded from 2000-2006 as lending standards declined dramatically, allowing homeowners to borrow much more against their homes.
2) As a result, the percentage of equity homeowners had in their homes fell below 50% for the first time, leaving many underwater. Private label mortgages like subprime, which were securitized by Wall Street, made up only 15% of mortgages but account for 51% of seriously delinquent loans.
3) Deregulation led to a surge in profits and compensation
1) The document contains musical notation for a jazz solo over the chord progression of Lester's Blues.
2) It is a solo performed by Dave Cliff on tenor saxophone.
3) The solo contains improvised lines over the standard 12-bar blues form, moving through the chord changes of G7, C7, and E7.
1. The document shows a floor plan with dimensions for a 63' by 24'8" commercial building space.
2. The floor plan details stairwell dimensions from the first to second floor, including 20 risers at 7" and 18 treads at 11".
3. Various room dimensions are indicated, including a 20' by 20' room labeled as "Shipping and Receiving".
Maria First Floor Reflectedceiling Planmariacadtech
1. The document is a reflected ceiling plan that shows the layout of the ceiling and lighting for the first floor of a commercial building.
2. It includes a legend defining the ceiling materials used, which are 2'x4' and 2'x2' acoustical panels suspended from a grid system.
3. Notes provide specifications for the ceiling suspension system, acoustical panels, installation requirements, and ceiling heights throughout the building.
T2 Partners Presentation On The Mortgage Crisisrossreller
This document provides an overview of the housing and credit crisis and why more problems are expected. It summarizes that loose lending standards from 2001-2006 led to a surge in risky mortgages. When home prices stopped rising rapidly in 2006-2007, these risky loans began defaulting in large numbers, especially the private label securities not backed by Fannie Mae or Freddie Mac. The crisis was caused by a combination of factors including loose lending, excessive risk taking on Wall Street to generate profits, and a belief that home prices would keep rising indefinitely. More defaults are expected as problem loans continue working their way through the system.
Purdue Me State Of The School June 2009lauramedwards
The document provides an overview of the School of Mechanical Engineering from June 2009. It discusses the people, learning, discovery, rankings, and development areas of the school. Key points include new faculty being added, undergraduate and graduate enrollment reaching all-time highs, high research expenditures and awards, strong US News rankings, and over $14 million raised for development in 2007-08.
This document contains sheet music for the folk song "Pretty Girl Milkin' Her Cow - Jig" arranged for ukulele. The sheet music displays the melody and chords using standard musical notation. It includes four verses of the song along with chord indications above the staff. A short description at the bottom provides attribution and copyright information for the sheet music.
Graph 1 matches Table 1 and the equation y = 3x + 2.
Graph 2 matches Table 2 and the equation y = 2x + 1.
Graph 3 matches Table 3 and the equation y = 1/2x + 1.
This document shows growth charts for weight and length in boys from birth to 6 months. The charts display percentiles for weight and length by age. They indicate average growth as well as ranges above and below average.
This document shows growth charts for boys from birth to 2 years of age. The charts track weight-for-age and length-for-age percentiles. Weight and length are plotted on the y-axis against age in months on the x-axis. The charts include reference percentiles of 3rd, 15th, 50th, 85th, and 97th to assess whether a child's growth matches what is typical.
1. A
PROGRRAM PROJECT PROPOSAL FOR SYSTEMS
BIOLOGY RESEARCH AT NIPER
Research project funded under XI five year plan
Controller & Coordinator: Nilanjan Roy PhD
4. Vision 2020; Indian paradox
Times of India, March 18, 2007
Source: “2006 World Population Prospects”
A report by UN Department of Economics and Social Affairs
5. Systems Biology at a glance
Genome Analysis Expression Analysis Proteome analysis
Interactome Analysis Pathway analysis Flux Balance Analysis
Sequence analysis Structural analysis
6. What
5.1 INSTITUTIONAL
Following institutional academic and research activity will be carried out in the
proposed program.
5.1.1 ACADEMIC PROGRAM:
Systems Biology course (M.S. Pharm.) in Biotechnology. Students from the
biotechnology department will be trained in this facility apart from their
departmental program.
5.1.2 RESEARCH
Following projects has been taken up under the scheme
Target discovery
1. Target for lifestyle diseases
a. Oxidative stress and Aging
b. Ischemic reperfusion injury
2. Targets for communicable diseases
a. Anti-protozoal
b. Anti-fungal
7. 5.1.1 ACADEMIC PROGRAM:
Systems Biology course (M.S. Pharm.) in Biotechnology. Students from the
biotechnology department will be trained in this facility apart from their
departmental program.
BT-540 SEQUENCE ANALYSIS (2 CREDITS)
1.Basics of computational biology
2.DNA & protein Sequence Analysis
3.Various methods of DNA and Protein comparison
4.Phylogenetic Analysis.
BT-660 SYSTEMS BIOLOGY (2 CREDITS)
1.Computational methods for Omics biology
2.Network construction and FBA
3.Computational methods for protein structure prediction
4.Computational methods for target based drug screening
10. How
System biology Work flow
From Omics to Target
Data from
Wet lab Insilico lab I Insilico lab II Insilico lab III
other lab 1. Microarray 1. Pathway analysis 1. Sequence analysis 1. Protein modeling
can also be 2. 2D-Gel Proteomics 2. Identification of 2. RT-PCR, Cloning 2. SAR, Active site
feed in key regulators support identification
System
biology
pipeline Software Software Software Software
R, ScanArray, Avadis, Pathway Studio, Chromas, GCG, MOE, Sybyl
PD Quest Matlab Vector NTI Schrodinger