1) Valved holding chambers (VHCs) are devices used with pressurized metered dose inhalers (pMDIs) to improve drug delivery to the lungs. They hold the aerosol cloud to allow particles to evaporate to a smaller size before inhalation.
2) Guidelines from regulatory agencies like the EMEA and FDA provide recommendations for characterizing VHCs and assessing their impact on aerosol particle size and drug delivery. Studies evaluate factors like delay time between actuation and inhalation.
3) Key attributes of VHCs include their size selective function, impact of delay time, effect of electrostatic charge, and how the drug and VHC type
1) Valved holding chambers (VHCs) are devices used with pressurized metered dose inhalers (pMDIs) to improve drug delivery to the lungs. They hold the aerosol cloud to allow particles to evaporate to a smaller size before inhalation.
2) Guidelines from regulatory agencies like the EMEA and FDA provide recommendations for characterizing VHCs and assessing their impact on aerosol particle size and drug delivery. Studies evaluate factors like delay time between actuation and inhalation.
3) Key attributes of VHCs include their size selective function, impact of delay time, effect of electrostatic charge, and how the drug and VHC type
Los números que usamos provienen de los algoritmos arábigos, los cuales fueron popularizados por los árabes aunque su origen se remonta a los fenicios. Estos algoritmos representan ángulos, con 1 siendo un ángulo, 2 siendo dos ángulos, y así sucesivamente hasta 9 ángulos. El cero representa cero ángulos.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Los números que usamos provienen de los algoritmos arábigos, los cuales fueron popularizados por los árabes aunque su origen se remonta a los fenicios. Estos algoritmos representan ángulos, con 1 siendo un ángulo, 2 siendo dos ángulos, y así sucesivamente hasta 9 ángulos. El cero representa cero ángulos.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.