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FGI
DIS (or Discon.)
DIS
DIS
DIS
DIS
DIS
DIS
DIS
(1,5-Dicarbonyl)
Avoid Cr(VI) reagent because it
provides cyclohexenone as side
pdt. Allylic C-H
oxidation
pdt.
DIS
(1,5-Dicarbonyl)
Better
this route
DIS
DIS
PhCHO + MeCOMe
DIS
DIS
Retro-Aldol
Retro-
Michael
DIS
Retro-
Aldol
DIS Retro-
Michael
(1,3-Dicarbonyl)
DIS
Retro-
Claisen
N CO2Et
DIS
Retro-
Michael
MeNH2
+
DIS
DIS
Retro-
Aldol
Retro-Michael
1st introduce methylvinyl
ketone, then methyl iodide and
then aldol reaction to cyclize
1.Base
2.
1. Base (1 eq.)
2. Me-I
DIS
Reconnection
DIS
Retro-
Diels-Alder
DIS
Retro-
Aldol
Reconnection
FGI
Santanu  06-26-2020 corrected by Dr S Dey.pdf

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