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The Right Iliac Fossa pain
Treatment Audit (The RIFT audit)
RIFT Audit Group - WMRC
J Matthews, S Jain, S Bhanderi, G Morley, D Nepogodiev,
J Glasbey, R Tyler, I Mohamed, R Wilkin, A Bhangu
Acknowledgements - E Griffiths, T Pinkney, O Gee, D Morton
RIFTstudy@gmail.com
@WMRC_UK #RIFTaudit
Timeline
November 30th
2016
March
2017
April
2017
End of
2017
June
2017
Background
Appendicitis
Gynae
Urology
Non specific
pain
Gastro
RIF Pain
“Sit Rep”
UK + ROI
Potentially 283 teams (? Less)
>3070 emails
>200 drafted documents
Adult 186 contacts
Paeds 24 contacts
REDCap 157 complete forms
>500 collaborators
? >4000 patients to be audited
?
“Sit Rep”
Regions Count of Involved Count of Region %
East Midlands 10 11 91
East of England 17 17 100
Jersey 1 1 100
Kent, Surrey and Sussex 12 18 67
London North Central and East 10 13 77
London North West 5 9 56
London South 10 11 91
North East 6 14 43
North West 13 28 46
Northern Ireland 7 10 70
Paediatric Surgery 24 27 89
ROI 16 16 100
Scotland 18 28 64
South West 10 14 71
Thames Valley 5 5 100
Wales 10 15 67
Wessex 7 9 78
West Midlands 15 18 83
Yorkshire and the Humber 13 18 72
Iberian peninusula 1 ?
Italy 65 ?
Grand Total 210 283 74
Aims and Standards
1) An initial laparoscopic approach should be used for appendicectomy unless
contraindicated
– [WSES Statement 5.1]
– [EAES Operative recommendations]
– (National Re-audit)
2) The normal appendicectomy rate should be <20%. For centres with higher or lower rates,
risk stratification data will allow interpretation of this rate in light of baseline case-mix.
1) The primary aim of this study is to determine the negative appendicectomy rate for
patients presenting with right iliac fossa pain.
2) Secondary aims of this study are:
i. to validate predictive risk scores for acute appendicitis;
ii. determine the laparoscopic appendicectomy rate in 2017;
iii. model variation in pathways for management of undifferentiated right iliac fossa pain;
iv. determine readmission rates for non-operated patients with RIF pain.
Risk stratification data using Alvarado/ AIR score will allow interpretation of individual
centres’ rates of negative and laparoscopic appendicectomy in light of their baseline case-
mix. A separate centre survey will profile local policy and service delivery for management
of RIF pain.
Potential Outcomes
1. New trainee collaborative networks
2. National re-audit of laparoscopy rate
3. National Re-audit of negative appendectomy rate
4. International comparison
5. Paediatric management
6. Variation between centres
7. Management differences depending on gender
8. “Incidence” of RIF pain
9. “Incidence” of Acute Appendicitis
10. “Incidence” of other pathologies and operations
11. “Incidence” of USS, CT and MRI + Findings
12. “Incidence” of risk score clinical usage
13. Calculated Risk Scores
14. Sensitivity + Specificity + PPV + NPV of the Risk Scores
15. Validated risk scores
16. Proposed pathways and guidance
Method - Scores
Data Point Alvarado AIR
Nausea Or vomiting 1 1
Anorexia 1
RIF Pain 2 1
Migration to RIF 1
Rebound or Gaurding 1 1 - 3
Temperature 1 1
WCC 2 1 - 2
Leukocytosis 1
Polymorphs 1 - 2
CRP 1 -2
Total Score 10 12
RIFTstudy@gmail.com
@WMRC_UK #RIFTaudit
Any questions?
https://www.google.com/maps/d/u/0/viewer?mid=1sEvEBGNBdSuXi0omb2
2vI4BCWVg&ll=48.52035371408743%2C2.4482682000000295&z=5
References
National Surgical Research Collaborative. Multicentre observational study of performance variation in
provision and outcome of emergency appendicectomy. Br J Surg [Internet]. 2013 Aug 1 [cited 2016 Sep
23];100(9):1240–52. Available from: http://onlinelibrary.wiley.com/doi/10.1002/bjs.9201/abstract
Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, et al. WSES Jerusalem guidelines for
diagnosis and treatment of acute appendicitis. World Journal of Emergency Surgery [Internet].
2016;11:34. Available from: http://dx.doi.org/10.1186/s13017-016-0090-5
Gorter RR, Eker HH, Gorter-Stam MAW, Abis GSA, Acharya A, Ankersmit M et al. Diagnosis and
management of acute appendicitis. EAES consensus development conference 2015. Surgical Endoscopy
[Internet]. 2016 Nov;30(11):4668-4690. Available from:
http://link.springer.com/article/10.1007/s00464-016-5245-7
Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT. Acute appendicitis: modern understanding of
pathogenesis, diagnosis, and management. The Lancet [Internet]. 2015 Sep;386(10000):1278–87.
Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673615002755

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RIFT Study WMRC Update March 17

  • 1. The Right Iliac Fossa pain Treatment Audit (The RIFT audit) RIFT Audit Group - WMRC J Matthews, S Jain, S Bhanderi, G Morley, D Nepogodiev, J Glasbey, R Tyler, I Mohamed, R Wilkin, A Bhangu Acknowledgements - E Griffiths, T Pinkney, O Gee, D Morton RIFTstudy@gmail.com @WMRC_UK #RIFTaudit
  • 4. “Sit Rep” UK + ROI Potentially 283 teams (? Less) >3070 emails >200 drafted documents Adult 186 contacts Paeds 24 contacts REDCap 157 complete forms >500 collaborators ? >4000 patients to be audited ?
  • 5. “Sit Rep” Regions Count of Involved Count of Region % East Midlands 10 11 91 East of England 17 17 100 Jersey 1 1 100 Kent, Surrey and Sussex 12 18 67 London North Central and East 10 13 77 London North West 5 9 56 London South 10 11 91 North East 6 14 43 North West 13 28 46 Northern Ireland 7 10 70 Paediatric Surgery 24 27 89 ROI 16 16 100 Scotland 18 28 64 South West 10 14 71 Thames Valley 5 5 100 Wales 10 15 67 Wessex 7 9 78 West Midlands 15 18 83 Yorkshire and the Humber 13 18 72 Iberian peninusula 1 ? Italy 65 ? Grand Total 210 283 74
  • 6. Aims and Standards 1) An initial laparoscopic approach should be used for appendicectomy unless contraindicated – [WSES Statement 5.1] – [EAES Operative recommendations] – (National Re-audit) 2) The normal appendicectomy rate should be <20%. For centres with higher or lower rates, risk stratification data will allow interpretation of this rate in light of baseline case-mix. 1) The primary aim of this study is to determine the negative appendicectomy rate for patients presenting with right iliac fossa pain. 2) Secondary aims of this study are: i. to validate predictive risk scores for acute appendicitis; ii. determine the laparoscopic appendicectomy rate in 2017; iii. model variation in pathways for management of undifferentiated right iliac fossa pain; iv. determine readmission rates for non-operated patients with RIF pain. Risk stratification data using Alvarado/ AIR score will allow interpretation of individual centres’ rates of negative and laparoscopic appendicectomy in light of their baseline case- mix. A separate centre survey will profile local policy and service delivery for management of RIF pain.
  • 7. Potential Outcomes 1. New trainee collaborative networks 2. National re-audit of laparoscopy rate 3. National Re-audit of negative appendectomy rate 4. International comparison 5. Paediatric management 6. Variation between centres 7. Management differences depending on gender 8. “Incidence” of RIF pain 9. “Incidence” of Acute Appendicitis 10. “Incidence” of other pathologies and operations 11. “Incidence” of USS, CT and MRI + Findings 12. “Incidence” of risk score clinical usage 13. Calculated Risk Scores 14. Sensitivity + Specificity + PPV + NPV of the Risk Scores 15. Validated risk scores 16. Proposed pathways and guidance
  • 8. Method - Scores Data Point Alvarado AIR Nausea Or vomiting 1 1 Anorexia 1 RIF Pain 2 1 Migration to RIF 1 Rebound or Gaurding 1 1 - 3 Temperature 1 1 WCC 2 1 - 2 Leukocytosis 1 Polymorphs 1 - 2 CRP 1 -2 Total Score 10 12
  • 9.
  • 10.
  • 12. References National Surgical Research Collaborative. Multicentre observational study of performance variation in provision and outcome of emergency appendicectomy. Br J Surg [Internet]. 2013 Aug 1 [cited 2016 Sep 23];100(9):1240–52. Available from: http://onlinelibrary.wiley.com/doi/10.1002/bjs.9201/abstract Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, et al. WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis. World Journal of Emergency Surgery [Internet]. 2016;11:34. Available from: http://dx.doi.org/10.1186/s13017-016-0090-5 Gorter RR, Eker HH, Gorter-Stam MAW, Abis GSA, Acharya A, Ankersmit M et al. Diagnosis and management of acute appendicitis. EAES consensus development conference 2015. Surgical Endoscopy [Internet]. 2016 Nov;30(11):4668-4690. Available from: http://link.springer.com/article/10.1007/s00464-016-5245-7 Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT. Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. The Lancet [Internet]. 2015 Sep;386(10000):1278–87. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0140673615002755

Editor's Notes

  1. Junior member with senior advisors and expert guidance Developing a cohort of juniors interested in collaborative research Juniors running the centres and collecting the data, its all about developing people A good gateway project We would like the registrats to run the centres and advice the juniors on data collection
  2. Validation needs methodical thought – Paul marriot Human error – missed cases – missed operations – missed histology – missed follow up ? Theatre log book – separate data collection method – separate to protocol HES data -? Done before
  3. RIF pain = common symptom Acute Appendicitis It is unknown how much of the RIF pain is appendicitis Proportion of RIF pain > Appendicitis There is a large variation in the investigation and management of RIF pain and AA Multiple Risk Stratification Scores exist
  4. RIF pain = common symptom Acute Appendicitis It is unknown how much of the RIF pain is appendicitis Proportion of RIF pain > Appendicitis There is a large variation in the investigation and management of RIF pain and AA Multiple Risk Stratification Scores exist
  5. RIF pain = common symptom Acute Appendicitis It is unknown how much of the RIF pain is appendicitis Proportion of RIF pain > Appendicitis There is a large variation in the investigation and management of RIF pain and AA Multiple Risk Stratification Scores exist
  6. We will ask centres to collect risk stratification data to allow comparison of local population variation Reducing unnecessary operations We want to remove the appendix’s of the true positives and avoid taking the false positives to theatre. Aim 1000 appendicectomies + 3-4000 RIF pain
  7. This audit will allow us collect data on these outcomes. Ensure imaging is used appropriately for high and low risk patients Next steps = Trial of Abx V lap, developed of new risk scores, encouraging adoption of best practice guidance, reducing unnecessary scans and operations, outcomes of leaving or removing normal appendixes
  8. Stay in contact with John – is he going to the collaborative meeting? WE need an admin role – keeping track of centres. Thuva – kick to do website Flow diagram of how to sign up – process Potential Jobs that could be done Admin SOP – flow diagram Admin excel = Master + regional tabs Admin excel = each hospital step by step in process Start pilot process – saleem + med students … ? Other centres ? Mr griffths or Pinkney as pilot lead
  9. WJES and BJS guidance suggests that we should risk score all RIF patients
  10. This study is now live, Weve got 20 sites already signed up, Please get in contact with us via this email. Summary for consultants = Abstract + responsibilities + authorship detail Registration – flow diagram