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Globalization
                      of the
Medical Technology Industry
                gy        y
  2012 Medical Device Manufacturing and R&D Summit


Thomas M. Loarie, Executive Chairman
         Mercator MedSystems, Inc.
Key Events 1960-2012
   Back to the Future

                 •For Profit Hospitals


House Calls   Hospital            •HMOs    •Segmentation
                                           •Doc in the Box    •Hospitals
                                                              M&A




   1960        1970           1980        1990         2000         2010



                                                              Health Reform
Key Events in MedTech 1960-2012

Cuts in Funding to AeroDefense                                        •Health Reform
                                                                      •ACOs
                                                                      •M&A Hospitals
                                 •TEFRA
                                                   •Kessler FDA
                                 •DRGs
                                                    M&A
                                                   •M&A
                    •FDA A t
                     FDA Act     •Segmentation
                                 •Marketing
                                                          Globalization




    1960          1970           1980            1990         2000            2010

                                                                          •The Great
              Social     •GoldStandard                                    Recession
              Security   •Emergence of    •FDA Modernization Act          •Implosion of
              Act of     Multi-National
                         Multi National   •CMS takes front seat
                                           CMS                            Venture Capital
              1965
Shifting Healthcare Priorities
    Convergence of Forces = Change

• Aging
   g g    p p
          population

• Chronic disease

• Increase in public spending

•P
 Pressure on govt. spending
                t      di

• Globalization of medtech

• Global middle class is
   booming

•    4    |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
World Population Ageing 1950-2050




 5   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
7   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
8   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Health Expenditures as
% of GDP




 9   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
10   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Globalization of U.S. Medical Care

• Global
       distribution of U.S.
 developed devices and drugs

• OUS clinical research

• Reverse brain drain
   • physicians & engineers

• Manufacturing expanded OUS

• U.S. multi-nationals expanding
  OUS p oduct research
        product esea c

  11   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
The Global Middle Class is Booming




    P. 12
Geopolitical Center is Shifting to Indian
Ocean from Atlantic
Shifting Healthcare Priorities
  Responses

• Utilization cuts
• Health Reform
• Harmonization of regs
• Science based adoption
• Globalization of delivery
• Destination medicine
•NNew h lth
        healthcare access
• Global competition
• Global consolidation




   14   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
15   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
16   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Health Reform


• Incentives shifting from financial to clinical
  – Quality and patient satisfaction are the metrics of the
    future
  – Decision shift from clinicians to “value committees”
  – Shift to value from incremental improvements
                                        p


• ACOs
  – Higher volume to fewer but larger customers



  17   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
18   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
19   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
20   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Globalization of Delivery

Ascension Health Alliance Invests in Cayman
 Medical Tourism Project (April 2012)
• Medical care
                   g              ,
  – for those living on the island,
  – the Caribbean region
  – and the USA.
• P t i with N
  Partnering ith Narayana H d
                          Hrudayalaya H
                                 l    Hospitals of I di
                                          it l f India
  – Adapt his Indian hospital technique of providing healthcare at low
    cost to a relatively high cost destination.
• The Health City is a US $2 billion project.



  21   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Globalization of Delivery

• UnitedHealth buys Brazilian provider, Amil, for
  almost $5 billion
 – Securing strong position in emerging market
 – Almost 200 million people
 – Market characterized as "under-penetrated”
American World Clinics




  22   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Destination Medicine




 23   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Destination Medicine
AKA Medical Tourism




 24   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
New Point of Access
26   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
27   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Global Competition

Minneapolis Star Tribune
September 28, 2012 - 9:30 PM
          28



Medtronic s
Medtronic's Chinese Buy Advances Global Strategy
Article by: JAMES WALSH

In June, Medtronic Inc. CEO Omar Ishrak told an investors' conference that
part of his company s mission for the future was "expanding access and
            company's                             expanding
enhancing value" in China.
In August, Ishrak told Medtronic shareholders that China "is a big piece" of
Medtronic's expectations for 20 percent annual growth in emerging markets.
M d      i '         i   f                    l      hi         i       k

• JNJ, Boston, Medtonic open research centers in China


      •28    |    © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
urin




 29    |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
The Future for Medtech
The Emerging U.S. Healthcare Eco-System
A Different Focus for Medtech




 31   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Generic Therapeutic Devices
A threat to legacy margins




 32   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Combating OUS Competition
Frugal Innovation




  33   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
eHealth
Facilitating Continuity of Care
Big Need - Solutions to Manage Costliest
Chronic Diseases




 36   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Expansion into Emerging Markets
Leverage New Points of Access
Technology Innovation
Productivity Continues to Improve




 40   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Regulation and Legislation




 42   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Global Experience
The U.S. Advantage

• Labor advantage
• Globally competitive
 – Goldman Sachs 25,000 (13,100 U.S.)
 – A l 60 400
   Apple 60,400
 – Microsoft 90,412
• America is ethnically blind
 – Google’s Sergy Brin
 – Univ of Chicago s Prof Ruoboni
           Chicago’s




  46   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
47   |   © 2012 Mercator MedSystems   |   All Rights Reserved   |   5/15/2012
Resetting the Vision for Medical Devices: How You and Your Company Can Thrive in the Emerging Global Healthcare Market - Thomas M. Loarie, Mercator MedSystems, Inc.

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Resetting the Vision for Medical Devices: How You and Your Company Can Thrive in the Emerging Global Healthcare Market - Thomas M. Loarie, Mercator MedSystems, Inc.

  • 1. Globalization of the Medical Technology Industry gy y 2012 Medical Device Manufacturing and R&D Summit Thomas M. Loarie, Executive Chairman Mercator MedSystems, Inc.
  • 2. Key Events 1960-2012 Back to the Future •For Profit Hospitals House Calls Hospital •HMOs •Segmentation •Doc in the Box •Hospitals M&A 1960 1970 1980 1990 2000 2010 Health Reform
  • 3. Key Events in MedTech 1960-2012 Cuts in Funding to AeroDefense •Health Reform •ACOs •M&A Hospitals •TEFRA •Kessler FDA •DRGs M&A •M&A •FDA A t FDA Act •Segmentation •Marketing Globalization 1960 1970 1980 1990 2000 2010 •The Great Social •GoldStandard Recession Security •Emergence of •FDA Modernization Act •Implosion of Act of Multi-National Multi National •CMS takes front seat CMS Venture Capital 1965
  • 4. Shifting Healthcare Priorities Convergence of Forces = Change • Aging g g p p population • Chronic disease • Increase in public spending •P Pressure on govt. spending t di • Globalization of medtech • Global middle class is booming • 4 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 5. World Population Ageing 1950-2050 5 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 6.
  • 7. 7 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 8. 8 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 9. Health Expenditures as % of GDP 9 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 10. 10 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 11. Globalization of U.S. Medical Care • Global distribution of U.S. developed devices and drugs • OUS clinical research • Reverse brain drain • physicians & engineers • Manufacturing expanded OUS • U.S. multi-nationals expanding OUS p oduct research product esea c 11 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 12. The Global Middle Class is Booming P. 12
  • 13. Geopolitical Center is Shifting to Indian Ocean from Atlantic
  • 14. Shifting Healthcare Priorities Responses • Utilization cuts • Health Reform • Harmonization of regs • Science based adoption • Globalization of delivery • Destination medicine •NNew h lth healthcare access • Global competition • Global consolidation 14 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 15. 15 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 16. 16 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 17. Health Reform • Incentives shifting from financial to clinical – Quality and patient satisfaction are the metrics of the future – Decision shift from clinicians to “value committees” – Shift to value from incremental improvements p • ACOs – Higher volume to fewer but larger customers 17 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 18. 18 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 19. 19 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 20. 20 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 21. Globalization of Delivery Ascension Health Alliance Invests in Cayman Medical Tourism Project (April 2012) • Medical care g , – for those living on the island, – the Caribbean region – and the USA. • P t i with N Partnering ith Narayana H d Hrudayalaya H l Hospitals of I di it l f India – Adapt his Indian hospital technique of providing healthcare at low cost to a relatively high cost destination. • The Health City is a US $2 billion project. 21 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 22. Globalization of Delivery • UnitedHealth buys Brazilian provider, Amil, for almost $5 billion – Securing strong position in emerging market – Almost 200 million people – Market characterized as "under-penetrated” American World Clinics 22 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 23. Destination Medicine 23 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 24. Destination Medicine AKA Medical Tourism 24 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 25. New Point of Access
  • 26. 26 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 27. 27 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 28. Global Competition Minneapolis Star Tribune September 28, 2012 - 9:30 PM 28 Medtronic s Medtronic's Chinese Buy Advances Global Strategy Article by: JAMES WALSH In June, Medtronic Inc. CEO Omar Ishrak told an investors' conference that part of his company s mission for the future was "expanding access and company's expanding enhancing value" in China. In August, Ishrak told Medtronic shareholders that China "is a big piece" of Medtronic's expectations for 20 percent annual growth in emerging markets. M d i ' i f l hi i k • JNJ, Boston, Medtonic open research centers in China •28 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 29. urin 29 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 30. The Future for Medtech
  • 31. The Emerging U.S. Healthcare Eco-System A Different Focus for Medtech 31 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 32. Generic Therapeutic Devices A threat to legacy margins 32 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 33. Combating OUS Competition Frugal Innovation 33 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 35.
  • 36. Big Need - Solutions to Manage Costliest Chronic Diseases 36 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 38. Leverage New Points of Access
  • 40. Productivity Continues to Improve 40 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 41.
  • 42. Regulation and Legislation 42 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 44.
  • 45.
  • 46. The U.S. Advantage • Labor advantage • Globally competitive – Goldman Sachs 25,000 (13,100 U.S.) – A l 60 400 Apple 60,400 – Microsoft 90,412 • America is ethnically blind – Google’s Sergy Brin – Univ of Chicago s Prof Ruoboni Chicago’s 46 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012
  • 47. 47 | © 2012 Mercator MedSystems | All Rights Reserved | 5/15/2012