Thanks	
  for	
  the	
  note	
  and	
  interest	
  in	
  the	
  research.	
  	
  Would	
  be	
  happy	
  to	
  do	
  more	
  studies,	
  including	
  some	
  with	
  alcohol	
  exposure,
but	
  this	
  requires	
  funding	
  that	
  the	
  government	
  is	
  reducing.	
  	
  Grants	
  in	
  this	
  area	
  are	
  simply	
  not	
  available,	
  so	
  other	
  sources	
  of
funding	
  are	
  needed.	
  	
  Such	
  a	
  study	
  would	
  run	
  easily	
  a	
  million	
  dollars	
  over	
  several	
  years	
  of	
  experiments.	
  	
  If	
  the	
  funding	
  become
available	
  will	
  certainly	
  consider.	
  	
  Michael	
  Skinner
On	
  8/5/15,	
  7:48	
  AM,	
  "barry	
  stanley"	
  <stanley_b@bell.net>	
  wrote:
Dear	
  Dr	
  Skinner
We	
  have	
  corresponded	
  over	
  the	
  years.
I	
  am	
  an	
  admirer	
  of	
  your	
  work,	
  and	
  persistence.
I	
  understand	
  why	
  you	
  have	
  not	
  addressed	
  in	
  the	
  past	
  the	
  epigenetic	
  effects	
  of	
  prenatal	
  alcohol	
  exposure,
including	
  the	
  pre	
  conceptual	
  effects	
  of	
  alcohol	
  on	
  the	
  father's	
  contribution	
  to	
  fetal	
  developmental	
  abnormalities.
However,	
  your	
  past	
  work	
  is	
  now	
  validated	
  and	
  accepted.	
  Meanwhile	
  the	
  role	
  of	
  PAE	
  in	
  epigenetics	
  has	
  been
well	
  established.
Could	
  you	
  please	
  give	
  more	
  consideration	
  to	
  the	
  epigenetic	
  effects	
  of	
  PAE	
  in	
  your	
  future	
  research?
Sincerely.
Barry	
  Stanley
Effect of environmental epigenetics on disease, evolution
'Epigenetics can drive genetics,' experts say
Date:August	
  3,	
  2015Source:Washington	
  State	
  UniversitySummary:Environmental	
  factors	
  are	
  having	
  an	
  underappreciated
effect	
  on	
  the	
  course	
  of	
  disease	
  and	
  evolution	
  by	
  prompting	
  genetic	
  mutations	
  through	
  epigenetics,	
  a	
  process	
  by	
  which
genes	
  are	
  turned	
  on	
  and	
  off	
  independent	
  of	
  an	
  organism's	
  DNA	
  sequence.	
  Researchers	
  assert	
  that	
  is	
  a	
  dramatic	
  shift	
  in	
  how
we	
  might	
  think	
  of	
  disease	
  and	
  evolution's	
  underlying	
  biology.
-­‐-­‐	
  
Michael	
  K.	
  Skinner
Eastlick	
  Distinguished	
  Professor	
  
and	
  Founding	
  Director
Center	
  for	
  Reproductive	
  Biology
School	
  of	
  Biological	
  Sciences
Washington	
  State	
  University
Pullman,	
  WA	
  99164-­‐4236
Phone:	
  509-­‐335-­‐1524
Fax:	
  509-­‐335-­‐2176
Email:	
  skinner@wsu.edu
Web:	
  www.skinner.wsu.edu
"Skinner, Michael K" <skinner@wsu.edu>
Re: Your great research
5 August, 2015 11:34 AM

Reply from Prof. Skinner

  • 1.
    Thanks  for  the  note  and  interest  in  the  research.    Would  be  happy  to  do  more  studies,  including  some  with  alcohol  exposure, but  this  requires  funding  that  the  government  is  reducing.    Grants  in  this  area  are  simply  not  available,  so  other  sources  of funding  are  needed.    Such  a  study  would  run  easily  a  million  dollars  over  several  years  of  experiments.    If  the  funding  become available  will  certainly  consider.    Michael  Skinner On  8/5/15,  7:48  AM,  "barry  stanley"  <stanley_b@bell.net>  wrote: Dear  Dr  Skinner We  have  corresponded  over  the  years. I  am  an  admirer  of  your  work,  and  persistence. I  understand  why  you  have  not  addressed  in  the  past  the  epigenetic  effects  of  prenatal  alcohol  exposure, including  the  pre  conceptual  effects  of  alcohol  on  the  father's  contribution  to  fetal  developmental  abnormalities. However,  your  past  work  is  now  validated  and  accepted.  Meanwhile  the  role  of  PAE  in  epigenetics  has  been well  established. Could  you  please  give  more  consideration  to  the  epigenetic  effects  of  PAE  in  your  future  research? Sincerely. Barry  Stanley Effect of environmental epigenetics on disease, evolution 'Epigenetics can drive genetics,' experts say Date:August  3,  2015Source:Washington  State  UniversitySummary:Environmental  factors  are  having  an  underappreciated effect  on  the  course  of  disease  and  evolution  by  prompting  genetic  mutations  through  epigenetics,  a  process  by  which genes  are  turned  on  and  off  independent  of  an  organism's  DNA  sequence.  Researchers  assert  that  is  a  dramatic  shift  in  how we  might  think  of  disease  and  evolution's  underlying  biology. -­‐-­‐   Michael  K.  Skinner Eastlick  Distinguished  Professor   and  Founding  Director Center  for  Reproductive  Biology School  of  Biological  Sciences Washington  State  University Pullman,  WA  99164-­‐4236 Phone:  509-­‐335-­‐1524 Fax:  509-­‐335-­‐2176 Email:  skinner@wsu.edu Web:  www.skinner.wsu.edu "Skinner, Michael K" <skinner@wsu.edu> Re: Your great research 5 August, 2015 11:34 AM