With more and more thesauri, classifications and other knowledge organization systems being published as Linked Data using SKOS, the question arises how best to make them available on the web. While just publishing the Linked Data triples is possible using a number of RDF publishing tools, those tools are not very well suited for SKOS data, because they cannot support term-based searching and lookup.
This webinar presents Skosmos, an open source web-based SKOS vocabulary browser that uses a SPARQL endpoint as its backend. It can be used by e.g. libraries and archives as a publishing platform for controlled vocabularies such as thesauri, lightweight ontologies, classifications and authority files. The Finnish national thesaurus and ontology service Finto, operated by the National Library of Finland, is built using Skosmos.
Skosmos provides a multilingual user interface for browsing and searching the data and for visualizing concept hierarchies. The user interface has been developed by analyzing the results of repeated usability tests. All of the SKOS data is made available as Linked Data. A developer-friendly REST API is also available providing access for using vocabularies in other applications such as annotation systems.
We will describe what kind of infrastructure is necessary for Skosmos and how to set it up for your own SKOS data. We will also present examples where Skosmos is being used around the world.
Da Biblissima a Biblissima+ : per un osservatorio delle culture scritteEquipex Biblissima
Présentation d'Anne-Marie Turcan-Verkerk lors de la LIBER Sixth Summer School on Trends in Manuscript Studies, University of Cassino (13 septembre 2021)
Da Biblissima a Biblissima+ : per un osservatorio delle culture scritteEquipex Biblissima
Présentation d'Anne-Marie Turcan-Verkerk lors de la LIBER Sixth Summer School on Trends in Manuscript Studies, University of Cassino (13 septembre 2021)
These slides were used during a brief presentation on RDM services at UCT Libraries Digital Library Services, as an introduction into an informal discussion with UCT Libraries' staff members around questions that refer to commonly used Research Data Management (RDM) terms and concepts.
The Use of Big Data Techniques for Digital ArchivingSven Schlarb
These slides were used in a presentation at the "Our Digital Future - Multidisciplinary Perspectives on Long Term Data Preservation and Access" conference in Cambridge/UK in March 2016 in the session "Current and Future perspectives on technology for data preservation and sharing". They describe work in progress in the E-ARK project, which is co-funded by the European Commission and has as its main objective the creation of a scalable open source, digital archiving system offering efficent search and access content of very large digital object collections. The focus of this presentation lies on describing the core big data technologies (Apache Hadoop, Apache Hbase, and the document repository Lily developed by NGData), the architecture of the E-ARK integrated prototype implementation, and data mining use cases related to geographical data, named entitity extraction, and OLAP data analysis.
LoCloud Vocabulary Services: Thesaurus management introduction, Walter Koch a...locloud
This presentation provides an introduction to thesaurus management in the LoCloud Vocabulary Services given during the LoCloud training workshops. It provides an introduction to controlled vocabularies, thesaurus for information retrieval and interoperability, to SKOS, multilingual vocabulary issues and to the federated model adopted for thesaurus management within the LoCloud service, which is based in TemaTres. The presentation includes a list of the vocabularies that have been integrated within the LoCloud service. There is also a walk-through of MediaThread and how this was used in the vocabulary management training offered in the workshop.
OOR Architecture - Towards a Network of Linked Ontology RepositoriesKim Viljanen
(Presented at the OOR Conference Call on Friday 19th November 2010.)
We propose a distributed OOR architecture consisting of simple APIs, ontology repository implementations conforming to these APIs and a registry of these repositories. Together these components create an OOR network that can be used to build services utilizing content from different ontology repositories. The approach is based on an observation that there are different kinds of use cases, ontologies, ontology service providers, etc., and therefore it may not be possible to implement a single OOR server that addresses all possible needs. We suggest that the OOR initiative should focus on APIs and enabling an ecosystem of ontology repositories, not on doing everything by ourselves. Test suites and baseline implementations for APIs are needed for validating API implementations on different ontology repositories and testing the APIs.
Presentation from Izaskun Lacunza, LIBER Executive Director in the Sweedish Library Days. The LIBER Strategy and its three priorities i) Scholarly Communications and Research Infrastructures, ii) Reshaping the Library and iii) Advocacy and Communications are discussed. The presentation focuses on how by association, better levels of dialogue can be reached with policy makers and rest of stakeholders
Thanks to digitization, today more than 55 million objects from the collections of Europe's libraries, archives and museums are available online to explore and reuse via Europe's digital library, Europeana. This talk will introduce some of the main activities, datasets and tools in the digitization of cultural heritage. The main focus will be on the Europeana Newspapers collection, a public domain licensed dataset of roughly 12 million pages of historic newspapers, and the possibilities and challenges in analyzing such large and heterogeneous textual resources with common NLP and machine learning tools.
Digital library initiatives in Turkey: A brief overviewYasar Tonta
Paper presented at 2009 ASIS&T Annual Meeting Thriving on Diversity - Information Opportunities in a Pluralistic World, November 6-11, 2009, Vancouver, British Columbia, Canada.
These slides were used during a brief presentation on RDM services at UCT Libraries Digital Library Services, as an introduction into an informal discussion with UCT Libraries' staff members around questions that refer to commonly used Research Data Management (RDM) terms and concepts.
The Use of Big Data Techniques for Digital ArchivingSven Schlarb
These slides were used in a presentation at the "Our Digital Future - Multidisciplinary Perspectives on Long Term Data Preservation and Access" conference in Cambridge/UK in March 2016 in the session "Current and Future perspectives on technology for data preservation and sharing". They describe work in progress in the E-ARK project, which is co-funded by the European Commission and has as its main objective the creation of a scalable open source, digital archiving system offering efficent search and access content of very large digital object collections. The focus of this presentation lies on describing the core big data technologies (Apache Hadoop, Apache Hbase, and the document repository Lily developed by NGData), the architecture of the E-ARK integrated prototype implementation, and data mining use cases related to geographical data, named entitity extraction, and OLAP data analysis.
LoCloud Vocabulary Services: Thesaurus management introduction, Walter Koch a...locloud
This presentation provides an introduction to thesaurus management in the LoCloud Vocabulary Services given during the LoCloud training workshops. It provides an introduction to controlled vocabularies, thesaurus for information retrieval and interoperability, to SKOS, multilingual vocabulary issues and to the federated model adopted for thesaurus management within the LoCloud service, which is based in TemaTres. The presentation includes a list of the vocabularies that have been integrated within the LoCloud service. There is also a walk-through of MediaThread and how this was used in the vocabulary management training offered in the workshop.
OOR Architecture - Towards a Network of Linked Ontology RepositoriesKim Viljanen
(Presented at the OOR Conference Call on Friday 19th November 2010.)
We propose a distributed OOR architecture consisting of simple APIs, ontology repository implementations conforming to these APIs and a registry of these repositories. Together these components create an OOR network that can be used to build services utilizing content from different ontology repositories. The approach is based on an observation that there are different kinds of use cases, ontologies, ontology service providers, etc., and therefore it may not be possible to implement a single OOR server that addresses all possible needs. We suggest that the OOR initiative should focus on APIs and enabling an ecosystem of ontology repositories, not on doing everything by ourselves. Test suites and baseline implementations for APIs are needed for validating API implementations on different ontology repositories and testing the APIs.
Presentation from Izaskun Lacunza, LIBER Executive Director in the Sweedish Library Days. The LIBER Strategy and its three priorities i) Scholarly Communications and Research Infrastructures, ii) Reshaping the Library and iii) Advocacy and Communications are discussed. The presentation focuses on how by association, better levels of dialogue can be reached with policy makers and rest of stakeholders
Thanks to digitization, today more than 55 million objects from the collections of Europe's libraries, archives and museums are available online to explore and reuse via Europe's digital library, Europeana. This talk will introduce some of the main activities, datasets and tools in the digitization of cultural heritage. The main focus will be on the Europeana Newspapers collection, a public domain licensed dataset of roughly 12 million pages of historic newspapers, and the possibilities and challenges in analyzing such large and heterogeneous textual resources with common NLP and machine learning tools.
Digital library initiatives in Turkey: A brief overviewYasar Tonta
Paper presented at 2009 ASIS&T Annual Meeting Thriving on Diversity - Information Opportunities in a Pluralistic World, November 6-11, 2009, Vancouver, British Columbia, Canada.
FLAX Weaving with Oxford Open Educational Resources: Open Practices for Engli...Alannah Fitzgerald
Workshop delivered at the e-Learning Symposium on the 25th of January, 2013 with the Centre for Languages, Linguistics and Area Studies at the University of Southampton.
Presentation given by Dr. Dimitris Gavrilis
Digital Curation Unit - IMIS, Athena Research Center
LoCloud Conference
Sharing local cultural heritage online with LoCloud services Amersfoort, Netherlands
5 February 2016
ARCLib project presentation from Pasig 2016dp-blog-cz
Digital preservation project by a group of Czech Libraries, financed by the Ministery of Culture of Czech Republic applied research grant. First information.
The IMLS-funded project Linked Data for Professional Education (LD4PE) has created a "Competency Index for Linked Data".
The Index provides a concise and readable map of concepts and skills related to the practices and technologies of Linked Data for the benefit of interested learners and their teachers.
The Research Data Alliance (RDA) has developed a Catalogue of Metadata standards and tools aimed at researchers and those who support them. In its new version, the Metadata Standards Catalog will provide much greater detail about metadata standards and tools, and through its new API - it will be usable within other applications. It will also provide a platform for furthering the work of the RDA Metadata Interest Group, which is seeking to improve the interoperability of metadata in different standards by working towards semi-automatically generated converters.
The International Treaty on Plant Genetic Resources for Food and Agriculture (ITPGRFA) calls for the contribution of non confidential information about the Plant Genetic Resources for Food and Agriculture (PGRFA) to the Global Information System (GLIS) to facilitate access to such information by any party interested. The foundation of GLIS is the accurate identification of the PGRFA to which the information is associated. After extensive research and consultation, DOIs have been selected as the Permanent Unique Identifier of choice for GLIS.
The webinar describes the challenges that the GLIS team of the ITPGRFA has faced as well as the benefits that the GLIS user community will receive by the adoption of DOIs.
Initially developed by FAO of the UN in the context of the NeOn project as a collaborative environment for the development of the AGROVOC thesaurus, later generalized to a SKOS-XLdevelopment platform in the context of a collaboration with the University of Rome Tor Vergata, VocBench is now reaching its third incarnation.
VocBench 3 (or simply, VB3), is the new version of VocBench, funded by the European Commission ISA² programme, and with development managed by the Publications Office of the EU, under contract 10632 (Infeurope S.A.).
VB3 will offer a powerful editing environment, with facilities for collaborative management of OWL ontologies and SKOS/SKOS-XL thesauri. VB3 will surpass its predecessor with native support for OWL, SKOS and SKOS-XL, completely rewritten components for better User Interface, User Management, History Tracking and Validation&Publication Workflow.
Research activities rely on access and repeatability of results. Accurate identification of the subject of the research as well as of the techniques and methods used is critical to obtain reliable results.
The adoption of Permanent Unique Identifiers, and specifically Digital Object Identifiers (DOIs)promotes access and reusability of data in modern research. The webinar begins with some basic concepts on Permanent Unique Identifiers. Next, DOIs are introduced describing how they are managed, how they can be obtained and how their features can be of benefit to researchers in a wide range of fields.
The FAIR principles have been introduced as a guideline for good scientific data stewardship. They have gained momentum at a management level and are now for example part of the project template for EU Horizon 2020 projects. This raises the question what research groups and projects can do to implement them. Hugo Besemer will introduce the ideas behind the FAIR principles.
By Ignasi Labastida is the Head of the Office the Dissemination of Knowledge at the Universitat de Barcelona
25 April 2017- 14:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
In 2006 the University of Barcelona launched the Office for the Dissemination of Knowledge (ODK) in order to make visible its commitment with openness started in 2003 when it joined Creative Commons as its host institution in Spain. Currently the ODK is based in the library and during these ten years has been involved in many activities, events, project and trainings to foster openness in any academic level from education to research. In this webinar, Dr. Labastida will explain how they have been developing this work and how the community has reacted.
By Sander Janssen, Research Team Leader of Earth Observation and Environmental Informatics at Alterra, Wageningen UR,
12 April 2017- 14:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
This presentation focus on the political context of open data publishing, methodological frameworks for estimating the impacts of open data and highlight the Open Data Journal for Agricultural Research as publication channel for open data sets. It will also build on personal reflections on publishing open data from Dr. Janssen’s own research career.
For more on the topic: http://aims.fao.org/activity/blog/join-free-webinar-publishing-open-data-agricultural-research
By Jennifer Chapin, Programme Manager, AuthorAID at INASP.
1 March 2017- 15:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
This webinar will provide an overview of the AuthorAID website and programme of support, including the online courses in research writing, mentoring support and resources. The impact of the AuthorAID programme and the lessons learnt in low income countries will also be covered.
About Jennifer Chapin
Jennifer coordinates the communication of research at INASP, managing the AuthorAID programme to support the capacity of researchers in developing countries. Joining INASP in 2016, Jennifer spent the previous four years at the Institute and Faculty of Actuaries in London, a role which included developing research best practice and quality assurance, supporting the development of actuarial research with 300 researchers worldwide. Holding an MA in Education and International Development, she previously worked in education strategy for the Royal College of Physicians of Canada and, since 2010, has also acted as director of a gender equality in education programme in Togo through a Canada-Togo partnership.
By Joy Paulson, the Director of the TEEAL Project and the International Projects Librarian at Mann Library, Cornell University.
24 February 2017- 15:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
TEEAL, The Essential Electronic Agricultural Library, is a database that provides access to peer-reviewed, research journals in Agriculture and related-sciences without the need for internet connectivity. Currently TEEAL provides access to 450 research journals. Additionally, TEEAL also begun to provide access to non-journal research material that can be difficult to find and access. The first collection is research sponsored by the Bill & Melinda Gates Foundation and its partners and grantees.
TEEAL is delivered on a small-footprint computer that can be plugged into an institution’s local area network (LAN) or a stand-alone computer. When connected to an institution’s LAN, TEEAL is available across the institution to all members of the institutions community.
This webinar will introduce the TEEAL database, explore its collections, and demonstrate methods for browsing and effectively searching to identify the research the user needs. Eligibility for TEEAL and costs will also be discussed. There will be an opportunity for questions.
About Joy Paulson
Joy Paulson is the Director of the TEEAL Project and the International Projects Librarian at Mann Library, Cornell University. She has been the Director of TEEAL for over 5 years, and she has taught international workshops on using TEEAL and other electronic resources, information literacy, scientific writing, and digital project management Africa and South Asia. Her previous work focused on developing digital library collections.
By by Kristin Kolshus, Information Management Specialist at FAO of the United Nations.
22 February 2017- 14:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
The objective of this webinar is to provide an overview of the AGORA programme for interested institutions in eligible countries. AGORA is one of the four Research4Life programmes. The webinar will present AGORA, a programme to provide free or low cost access to major scientific journals in agriculture and related biological, environmental and social sciences to public institutions in developing countries. The webinar will focus on the eligibility, the registration, terms of use, and the types of resources covered.
About Kristin Kolshus
Kristin Kolshus is an Information Management Specialist at the Food and Agriculture Organization of the United Nations (FAO), Regional Office for Africa. She focuses on capacity development on access to scientific information, information management, and knowledge sharing, especially through AGORA and Research4Life.
By Thembani Malapela, Knowledge and Information Management Officer at FAO of the United Nations.
21 February 2017- 15:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
AGRIS is the International System for Agricultural Science and Technology. It is supported by a large community of data providers, partners and users. AGRIS is one of the many bibliographic databases used for locating agricultural information online, others examples include PubAg, TEEAL and CAB Abstracts.
AGRIS is a database that aggregates bibliographic data, and through this core data it retrieves related content across online information systems by taking advantage of Semantic Web capabilities. Through AGRIS core data, related content across online information systems is retrieved thereby enriching the search results.
This webinar will present the AGRIS international initiative and partnership, looking at how AGRIS bibliographic data acts as a gateway to enable researchers and policy makers to retrieve agricultural and scientific information. The end-user based webinar will explain the fundamentals of AGRIS, give an overview of the AGRIS interface, and show how users can initiate their searches using both the simple and advanced search functionalities.
About Thembani Malapela
Thembani Malapela works as Knowledge and Information Management Officer at the Food and Agriculture Organisation of the United Nations. Currently, he is responsible for AGRIS user support and communications and in evaluating various ways of improving the AGRIS user experience.
By Chenjerai Mabhiza, Head of User Services at the University of Namibia
17 February 2017- 15:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
By Thomas Ingraham, Publishing Editor at F1000Research
15 February 2017- 15:00 CET
--The webinar was held as part of ASIRA (Access to Scientific Information Resources in Agriculture) Online Course for Low-Income Countries--
This webinar covers three emerging themes in life science publishing, which will begin to influence the way in which the agricultural researchers share and access knowledge:
Faster dissemination: Publishing scientific articles is often a lengthy process, taking several months or even years from first submission. This prevents the research community and others from being able to act on new knowledge quickly, which is especially serious in emergency situations such as emerging infectious diseases. This webinar will cover two ways of tackling publication delays: preprint servers and post-publication peer review platforms.
Increased access & transparency: Open Access has helped remove access barriers to a vast body of scientific knowledge. Other important research outputs that have historically been difficult to access are starting to be published more frequently such as replications, data, code and referee reports.
Assessment of research: Researches are assessed by their publication record. Journal title and Impact Factor tend to be the default assessment criteria, though there is growing awareness of the disadvantages of these approaches, and alternative measures of quality and impact are gaining ground.
About Thomas Ingraham:
Tom is the Publishing Editor at F1000Research and has been involved with the publisher’s open science and editorial development since its inception in 2012. He manages several channels published on F1000Research, including those focussing on agriculture, and is the lead on several of the publisher’s open data-orientated projects.
Open access has been a positive force in scientific publishing. But the removal of paywalls and restrictive licencing are not the only issues that need to be tackled; unnecessary delays to publication, irreproducible findings, publication biases, and poor access to underlying data and code also need to be addressed. This is especially important in agriculture and nutrition research where quick, unrestricted access to knowledge is crucial to solving urgent issues including food security, biodiversity conservation, and emerging infectious diseases in crops and animals.
This webinar will cover how the novel approaches taken by the publication venue Open Knowledge in Agricultural Development (OKAD) and the publishing platform it is hosted on, F1000Research, are addressing these issues. OKAD publishes academic articles, posters and slide presentations involving open knowledge projects within all areas of agriculture, nutrition and agro-biodiversity. By using F1000Research’s post-publication peer review platform, OKAD ensures rapid access to research within days of submission. Experts are invited to peer review upon publication, and their signed peer review reports are published alongside the article. All articles and any associated data and code are made publically available.
AGRIS is the International System for Agricultural Science and Technology. It is supported by a large community of data providers, partners and users. AGRIS is a database that aggregates bibliographic data, and through this core data, related content across online information systems is retrieved by taking advantage of Semantic Web capabilities.
This webinar will present AGRIS international initiative and partnership in the usage of AGRIS bibliographic data as a gateway to enable researchers and policy makers to retrieve agricultural and scientific information. The end-user based webinar will explain the basic fundamentals of AGRIS, overview the AGRIS interface, and how users can initiate their searches using both the simple and advanced search functionalities.
Le programme Research4Life est un partenariat public-privé entre l’OMS, la FAO, le PNUE, l’OMPI, les Universités Cornell et Yale, des partenaires technologiques et plus de 200 éditeurs scientifiques représentés par l’Association internationale des éditeurs de la STM.
Le programme fournit aux pays à revenu plus faible et moyen, un accès gratuit ou à faible coût aux plus grandes collections de publications en ligne. Les bibliothèques admissibles au programme bénéficient de plus de 68 000 revues scientifiques internationales, livres et bases de données dans les domaines de la santé, de l’agriculture, de l’environnement et de la technologie.
L’objectif de Research4Life est de réduire l’écart des connaissances entre les pays industrialisés et les pays en développement.
Ce webinaire présente comment Research4Life fonctionne, comment le programme est structuré et qui peut se joindre au partenariat. Il donnera un aperçu de l’accès aux quatre programmes Hinari, AGORA, OARE et ARDI qui composent Research4Life.
De plus, il présentera brièvement la formation gratuite disponible sur les sites web sur les compétences des auteurs, les outils de gestion de référence mais aussi fournira des exemples de comment Research4Life fait la différence pour de nombreux établissements de recherche aujourd’hui.
Research4Life es una colaboración pública-privada de la Organización Mundial de la Salud (OMS), la FAO, el Programa de las Naciones Unidas para el Medio Ambiente (PNUMA), la Organización Mundial de la Propiedad Intelectual (OMPI), las bibliotecas de las universidades de Cornell y Yale, la Asociación Internacional STM y más de 200 editoriales internacionales. Brinda acceso libre o de bajo costo a contenido en línea revisado por pares académicos y profesionales en países en vías de desarrollo.
Instituciones elegibles y sus empleados y estudiantes tienes derecho a acceder a hasta 68,000 recursos de las principales revistas, bases de datos y del Internet en los ámbitos de la agricultura, las ciencias biológicas, medio ambientales y sociales relacionadas.
La meta de Research4Life es empoderar a instituciones científicas es países con bajos y medios ingresos y reducir las brechas en el conocimiento.
Este seminario mostrará el funcionamiento y la construcción de Research4Life, así como también quién puede participar en la colaboración. Presentará los cuatro programas de Research4Life: Hinari, AGORA, OARE y ARDI, que brindan acceso a los ámbitos mencionados. Además ofrecerá un resumen sobre capacitación proporcionada en la página web sobre competencias de la autoría, herramientas de la gestión de referencias etc. y proporcionará ejemplos de cómo Research4Life hace una diferencia para muchas instituciones científicas.
Research4Life is a public-private partnership of the WHO, FAO, UNEP, WIPO, Cornell and Yale Universities, the International Association of Scientific, Technical & Medical Publishers and over 200 international scientific publishers. It provides developing countries with free or low cost access to academic and professional peer-reviewed content online. Eligible libraries and their users benefit from online access to up to 68,000 peer-reviewed international scientific journals, books, and databases in the areas of health, agriculture, environment and technology.
The overall goal of Research4Life is to empower research institutions in developing countries and to reduce knowledge gaps.
This webinar will illustrate how Research4Life works, how it is constructed and who can join the partnership. It will briefly present the four Research4Life programs Hinari, AGORA, OARE and ARDI that provide access to the aforementioned research areas. Furthermore it will give an overview about free training provided on the website about authorship skills reference management tools etc. and provide examples of how Research4Life could make a difference for many research institutions already.
To help reaching the Sustainable Development Goals, CGIAR must tap into Big Data. Within the programme on Climate Change for Agriculture and Food Security (CCAFS), researchers have already applied Big Data analytics to agricultural and weather records in Colombia, revealing how climate variation impacts rice yields. After defining its Open Data-Open Access strategy, CGIAR has launched an internal call for proposals for big data analytics platforms that will provide services to the Agri-Food system programmes and parners, and will interconnect the CGIAR data to other multi-disciplinary big data. The seminar will present the pespectives of the envisioned platforms.
More from AIMS (Agricultural Information Management Standards) (20)
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
2. About the National Library of Finland
● The National Library of Finland is the
oldest and largest scholarly library in
Finland. Our origins date back to 1640,
when the Academy of Turku was
founded.
● We are responsible for the collection,
description, preservation and
accessibility of Finnish printed national
heritage and the unique collections
under its care.
● We provide the Finnish Thesaurus and
Ontology Service Finto, a platform for
publishing controlled vocabularies,
implemented using Skosmos software.
3. How do you put a
thesaurus*
on the web?
* or any KOS: classification, authority file, term list, lightweight ontology...
23. Skosmos is open source software
● Available under MIT License
● Developed on GitHub
https://github.com/NatLibFi/Skosmos
● Major versions released every 2-3 months
○ Skosmos 1.5 released 18 February 2016
○ Skosmos 1.6 currently under development
24. Implementation
● PHP with Twig templates
● EasyRdf for SPARQL access and RDF
parsing
● Several JavaScript libraries for the UI
26. Key features
● Multilingual browser interface (10 languages)
○ Autocomplete search
○ Alphabetical index
○ Concept hierarchy display
○ Concept groups (thematic index)
○ New concepts
● REST API for enabling use of vocabularies
in other applications
○ responses usually JSON-LD
27. User groups
● Indexers who describe documents
● Thesaurus managers
● Software developers
28. Skosmos around the world
UN ● FAO: Skosmos used for publishing AGROVOC
● GACS project (FAO, CABI (UK), NAL (USA)) is using Skosmos
● UNESCO is planning to use Skosmos for publishing its thesaurus
Germany ● Rheinland-Pfalz spatial data infrastructure: publishing classifications
● German National Library of Economics (ZBW)
● North Rhine-Westphalia university library centre (HBZ-NRW):
publishing classifications
France ● Institute for Demographic Studies INED: publishing Demovoc thesaurus
● Sparna (helping UNESCO and INED in deploying Skosmos)
Italy ● University of Tor Vergata (developers of VocBench thesaurus editor)
Austria ● University of Vienna, Phaidra projject
Norway ● Oslo University Library Norwegian General Thesaurus project
Finland ● Terminollogy Centre TSK
● Lingsoft Oy
● SeCo research group light.onki.fi
● Mikkeli University of Applied Sciences
30. Requirements
● SPARQL 1.1 endpoint
○ with one or more SKOS vocabularies
○ recommended: Jena Fuseki with jena-text index
● server with Apache and PHP
See documentation in the Skosmos wiki:
https://github.com/NatLibFi/Skosmos/wiki
- New install tutorial with Fuseki 2 and Skosmos
Join the Google Groups user forum:
https://groups.google.com/forum/#!forum/skosmos-users
34. Major users of Finto
● Many libraries
● Many museums
● Finnish Broadcasting Company Yle
○ archives, Svenska Yle (Swedish language news)
● National Institute for Health and Welfare
● Prime Minister’s Office
○ government web portals
● Ministry of Employment and Economy
○ EnterpriseFinland portal
● National Land Survey
● City of Helsinki
35. Ontology development & publishing
TopBraid
Composer SE
(local installs)
Jena SDB
triple store
(MySQL)
Jena Fuseki
triple store
TDB + text
VPN
connection
Finto-data
GitHub
repository
hourly
dump
Skosify
daily conversion
to SKOS
immediate
publishing
after SKOS
conversion
Finto.fi
Skosmos
installation
Varnish HTTP cache