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3. Table of content
Introduction
Review of literature
Definitions
Classification of mandibular defects
Physiology of oral function following
resection
Diagnostic Consideration for Prosthodontic
rehabilitation
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4. Prosthodontic management
Mandibular guidance prosthesis
Partially edentulous patient
Completely edentulous patient
Role of implants in rehabilitation
Summary
Conclusion
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5. Introduction
Management of malignant tumors involving the
tongue,
mandible,
and
adjacent
structures
represents a difficult challenge for both the
reconstructive
surgeon
and
prosthodontist.
Rehabilitation is an essential phase of cancer care
and should be considered from the time of
diagnosis. Surgical resection often creates large
defects accompanied by dysfunction,
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6. and disfigurement while radiation therapy produces
significant morbidity and unique tissue management
problems. Speech, swallowing, control of saliva and
mastication can be adversely affected. These cosmetic
and
functional impairments should be corrected or
minimized, thereby allowing the patient to resume a
normal working and social life.
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8. mandibular resection: the surgical removal
of a portion or all of the mandible and the
related soft tissues called also
mandibulectomy
mandibular resection prosthesis : a
maxillofacial prosthesis used to maintain a
functional position for the jaws (maxillae
and mandible), improve speech and
deglutition following trauma or/and surgery
to the mandible or/and adjacent structures
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9. mandibular repositioning : guidance of the
mandible to cause closure in a
predetermined, altered position
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11. Prosthetic treatment of maxillofacial injuries
JPD 1955: Lt Colonel Edwin
Reviewed treatment of maxillofacial injuries.
He stressed the need for efficiency and
simplicity of appliances. He outlined several
designs for various types of defects. The
principles outlined by him are still followed.
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12. Prosthetic reconstruction of a resected
mandible
JPD 1962: Adisman
Described a case report of management of a
patient with resection of mandibular body
from 1st molar of one side to other side,
anterior 2/3 tongue and dorsum of tongue
sutured to mucosa of lower lip.
Mandibular expansion with implant prosthesis
and rehabilitation with RPD was done.
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16. Use of a guide plane for maintaining the
residual fragment in partial or
hemimandibulectomy
JPD 1964: Robinson and Rubright
Described a simple guide plane from pre-
surgical impression and designed to maintain a
functional occlusal relationship as a postsurgical splint. Such a splint compensates for
uncontrolled muscular contraction.
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17. Prosthetic mandible of resected edentulous
mandible
JPD 1969: Swoope
He advocated the use of uncomplicated
appliances for treatment of edentulous patient
with partially resected mandible utilizing
fundamental principles of denture
construction. A ramp can be provided on
maxillary denture to serve as training device
for returning the mandible to a functional
position.
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18. Prosthetic management of edentulous
mandibulectomy patient
Cantor and curtis
JPD 1971
Part I : Anatomic, physiologic and
psychologic consideration
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19. Presents physiologic consideration pertinent
to mandibulectomy patients discussed in
terms of functional adaptibility to surgical
insult. Deglutition, speech, mandibular
movement, mastication, respiration, salivary
control and psychologic factors have been
discussed. A classification for
mandibulectomy patients has been
suggested.
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20. Part II ; Clinical procedures
Describes prosthetic principle relevant to post-
surgical conditions of radical mandibular
surgery. It describes clinical procedure to treat
the same. A clinical study of 30
mandibulectomy patients was undertaken to
make an objective assessment of the
procedures.
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21. Rehabilitating dentulous hemimandibulectomy
patients
Moore and Mithchel : JPD 1976
Describes a technique that combines crowns
with a maxillary prosthesis to guide a
dentulous hemimandible into its most
functional position after long term scarring and
deviation to the affected surgical site.
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23. Occlusal consideration for the partial
hemimandibulectomy patients
Desjardin: JPD 1979
Described various occlusal consideration for
continuity and discontinuity defects in
edentulous and partially edentulous patients.
The occlusal scheme varies from person to
person. If the continuity of the mandible can
be restored by secondary surgical management
most of the problems of the discontinuity can
be resolved.
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24. Reduction of the median mandibulectomy with the
fixed mandibular implant.
Goodwin et al : J oral max surg 1992
50(3):292-6
A technique is presented whereby a median
mandibulectomy of an atrophic edentulous
mandible is performed to gain access to an
oropharyngeal tumor and is subsequently
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25. reapproximated with a four-pin FMI. The
procedure allows reduction of the osteotomy
site and provides intraoral implants that
increase the stability and retentive properties
of a mandibular prosthesis.
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26. Titanium osseointegrated implants combined
with hyperbaric oxygen therapy
in previously irradiated mandibles
Arcuri et al : JPD 1997;77:177-83
This report presents the preliminary results
of placing 18 titanium screw implants into
previously irradiated mandibles in conjunction
with hyperbaric oxygen therapy. Results. Of
the 18 implants placed, 17 (94%)
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27. were judged to be osseointegrated at the
abutment. The use of implants in irradiated
tissues may provide a means of enhancing
prosthetic rehabilitation while reducing the
risk of tissue trauma that may develop into
osteoradionecrosis
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28. Arrangement of artificial teeth in the neutral
zone after surgical reconstruction of the
mandible: A clinical report
Fukushima, sato et al: JPD 2002;88:125-7
This clinical report describes the fabrication
of a fixed partial denture, supported and
retained by implants, for a patient with
unfavorable tongue movement caused by
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29. movable grafted skin on the floor of the
mouth after surgical reconstruction of the
mandible. The neutral zone technique was
used, and successful results were obtained.
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30. Rehabilitation of an irradiated mandible after
mandibular resection using
implant/tooth-supported fixed prosthesis: A
clinical report
Levin et al :J P D 2004;91:310-4
The patient presented with an unstable
removable partial denture compromised by
mandibular resection. Previous irradiation
of the mandible did not compromise the
integration of
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31. the implants, thus enabling a fixed
rehabilitation. At first stage, a provisional
implant-supported fixed partial denture that
functioned as a positioning and guiding plane
determined the intermaxillary relationship.
The definitive metal ceramic restoration had
the same interocclusal relationship established
by the mandibular guidance device.
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32. An implant-supported fixed prosthesis can
provide an effective functional and
predictable solution for patients undergoing
mandibular resection and irradiation.
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34. Chalian (1985a)
Class I Resection of the ipsilateral condyle
Class II Resection of the ipsilateral condyle and ascending
ramus
Class III Resection of the ipsilateral condyle and body to
midsymphysis
Class IV Resection of the ipsilateral condyle to the
contralateral body
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35. Class V Total mandibulectomy
Class VI Resection of the midsypmphysis
Class VII Segmental resection of the body
Class VIII Marginal or coronal resection of the
body.
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36. Urken et al. (1991)
Urken classification of mandibular defects:
C-condyle, R-ramus, B-body, SH-symphysis (half)
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37. Cantor and Curtis
6 different categories based on extent of the defect and the
method of restoration in edentulous patients.
Class I - Radical alveolectomy with preservation of
mandibular continuity
Class II - Lateral resection of the mandible distal to the
cuspid area
Class III - Lateral resection of the mandible to the midline
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44. Class IV - Lateral bone graft and surgical
reconstruction
Class V - Anterior bone graft and surgical
reconstruction
Class VI - Anterior mandibular resection without
surgical reconstruction
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45. Physiology of oral functions
The nature and extent of disability depends
on the
location and size of tumour
Impact of radiation/ chemotherapy
Structure and volume of tissue resected
Design of resection
Method of resection
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47. Deglutition
May be temporarily or permanently disrupted
Usually returns as swallowing is a primary
function
It can be performed with minimal muscular
function and even with loss of skeletal structures
such as mandible and hyoid bone.
However tissue loss and reduced neuromuscular
control of oral and laryngeal structures will restrict
the anterior elevation of the floor of the mouth.
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48. Dysfunction occurs due to
Dennervation
Scarring
Radiation fibrosis
Tongue resection
Discontinuity defect
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50. Speech distortion usually occurs in
mandibulectomy patients due to impairment
of the articulating mechanism or resonating
chambers.
Reduction in tongue size or mobility
Displacement of mandibular fragment will
cause asymmetric functioning of the tongue
Scarring of lower lip can interfere with
sound production.
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51. Mandibular movement and mastication
There is alteration and restriction of
mandibular movement.
The remaining mandibular segment will
retrude and deviate towards the surgical
side at rest position. Upon opening the
mouth this deviation will increase leading to
angular pathway of opening and closing.
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54. Loss of proprioceptive sense of occlusion
leads to uncoordinated less precise
movements, loss of masticatory muscles on
surgical side will result in significant
rotation of mandible upon forceful closure.
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57. Saliva control
Drooling can occur due to
Restricted tongue movement
Difficulty in swallowing
Absence of labial, buccal and lingual sulci
Scarring of orbicularis oris
Loss of sensory awareness
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58. Xerostomia
Reduced salivary flow which is thick and
ropy.
Degeneration of salivary glands due to
irradiation
Denture retention, tissue tolerance and taste
adversely affected
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67. Location and extent of mandibular
defect
Continuity defect
Discontinuity defect
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68. Continuity defect
Radical alveolectomy
Reduction in stability of prosthesis due to
loss of vertical ridge height and vestibular
depth.
Vertical discrepancy between level of
residual osseous support an opposing
dentition at the level of occlusal plane.
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70. Discontinuity defect
Rule of thumb: The further anterior the
defect the more disfiguring and functionally
debilitating it is likely to be.
Defects of symphyseal region always
require surgical reconstruction before
prosthodontic therapy can be effective.
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72. Defects of posterior mandible can be
restored to near normal mandibular mobility
with immediate or delayed surgical
reconstruction.
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73. Presence of remaining natural teeth
Teeth are crucial to stability of prosthesis.
Prognosis improves as no.. of teeth
increase.
Teeth present bilaterally
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74. Rotation and deviation of mandible
Deviation towards the defect side occurs
due to loss of tissue and primary closure
drawing the margins together.
Loss of continuity also results in inferior
rotation of mandible
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76. Results of deviation and rotation are
Facial disfigurement
Loss of occlusal contact
Loss of ability to bring the lips together for
salivary control.
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78. Mouth opening
Many patient experience limitation of
mouth opening after mandibulectomy due
to surgical trauma and scar formation
Sufficient mouth opening to allow dental
access and making of impression is
paramount.
Prevention of scar tissue formation by
stretching exercise soon after surgery
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79. Vestibular extension
Normal vestibule is important to alow for
extension of flanges for maximum support ,
stability and perepheral seal asociated with
retension.
Loss of vestibular depth adversely affects
prognosis
Secondary surgery – vestibuloplasy must be
done even if continuity of mandible exists.
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81. Tongue mobility
Frequently surgical wound is closed by
suturing remaining tissue of floor of mouth
or tongue to buccal tissue. This limits
mobility of tongue.
Affects speech, swallowing, mastication,
prosthesis control and control on food
bolus.
Tongue mobility must be evaluated
Lingual vestibuloplasty, Speech therapy
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84. Mandibular guidance prosthesis
Begins 2 weeks after surgery
Presence of teeth essential. Excessive lateral
forces generated during guidance of
mandible can dislodge complete denture.
Can be constructed on maxilla or mandible
Once acceptable occlusal relationship is
attained guidance prosthesis can be
discarded.
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85. 1 Obtain maxillary and mandibular
impression and pour the cast
2 Wax interocclusal record obtained by
clinician by guiding mandible into best
possible interocclusal relation
3 Cast mounted on articulator and studied
4 Occlusal equilibration done
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86. Diagnostic cast of mandible is surveyed and
RPD design outlined.
Engage maximum no.. Of teeth. Guidance
flange extended from continuous clasp on
buccal aspect .
The guidance ramp must extend superiorly
in a diagonal manner to allow for normal
overlap of maxillary and mandibular teeth.
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88. If an acrylic ramp is planned a retentive
mesh must be placed extending from
continuous buccal clasp on non-defect side.
To decide angulation of ramp a second wax
record obtained with posterior teeth
separated upto 3mm and mandible deflected
maximum towards non-defect side is
obtained and used to articulate cast.
Wax pattern of framework and flange s
designed and casted
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90. If acrylic ramp is planned, then
autopolymerizing resin at dough stage is
attached to retentive mesh placed in patients
mouth and mandible guided repeatedly into
desired position.
Resin manipulated to extend 7-10mm
superiorly.
Prosthesis removed, allowed to polymerize,
trimmed and polished.
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91. Resin ramp can be periodically assessed
and adjusted unlike metal ramp
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92. Maxillary guidance ramp is made of acrylic.
The full palatal coverage prosthesis is
constructed and tried in the mouth.
Autopolymerizing acrylic resin is added to
palatal aspect along the lateral and anterior
border on the non-defect side.
The prosthesis is replaced in mouth and
mandible manipulated to desired position
thus establishing a index in palate.
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