Ppt presentation on Diabetic Nephropathy

1. MED STUDENT: JUSTIN ALLEN SUPERVISOR: DR. SIDDIQUI
DIABETIC NEPHROPATHY

2. DIABETIC NEPHROPATHY
What is Diabetic Nephropathy
& common risk factors?
Pathophysiology of Disease What are the common
Symptoms?

3. DIABETIC NEPHROPATHY
What will be seen on
labs?
What is the treatment? What are some
lifestyle Modifications?

4. WHAT IS A DIABETIC KIDNEY?
What is Diabetic nephropathy? Risk Factors
 Damage to the small microvasculature in the
kidneys known as Glomeruli that filter the blood
of majority of all substances such as glucose,
amino acids, Bicarbonate, Na+, k+ and much
more.
 Uncontrolled hyperglycemia
 Uncontrolled hypertension
 Smoking
 High blood cholesterol
 Obesity
 Family Hx of type 1 or type 2 diabetes

5. PATHOPHYSIOLOGY OF DIABETIC NEPHROPATHY
 High serum glucose leads to no enzymatic glycoslation of the vascular basement membrane resulting in
hyaline arteriosclerosis.
 Which is more affected the afferent or the efferent arteriole? The efferent arteriole is most affected
leading to high glomerular filtration pressure.
 This hyper-filtration injury therefore causes an isolated result of albuminuria (protein in the urine) at the
beginning stages.
 Without treatment it will lead to a nephrotic syndrome that is characterized by sclerosis of the
mesangium with classical histological imaging of Kimmelstiel-Wilson nodules in the glomeruli.

6. COMMON SYMPTOMS OF DIABETIC NEPHROPATHY
 High blood pressure that gets harder to conrtrol
 Swelling of the feet, ankles or even the eyes
 Foamy Urine
 Confusion or difficulty thinking
 Shortness of breath
 Los of appetite
 Nausea, vomiting, itching, or even fatigue

7. LAB RESULTS OF DIABETIC NEPHROPATHY
Lab results Clinical Labs

8. TREATMENT OF DIABETIC NEPHROPATHY
Control hypertension Control hyperglycemia

9. LIFESTYLE MODIFICATIONS
Quit Smoking, Control hypertension
& Hyperlipidemia
Diet & Exercise
Weight loss

10. THANK YOU
JALLEN1@VILLAGEMEDICAL.COM