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Determination of antibody titres in adult stray/free roaming and domestic canines against anti-rabies immunization by RFFIT A Preliminary report Pimburage R M S 1 , Gunatilake M 2 , Wimalaratne O 3 , Balasuriya A 4 , Perera K A D N 3 1 Deprtment of Public Health Veterinary Services, Ministry of Health 2 Department of Physiology, Faculty of Medicine, Colombo 08 3 Department of Rabies Research and Vaccine Quality control, Medical Research Institute, Colombo 08 4 Faculty of Medicine, General Sir John Kotelawala Defence University
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[object Object],[object Object],[object Object],[object Object],Recommended Anti Rabies vaccine schedule : Age 6 weeks 3 months Annual Vaccination 1 st dose 1 st booster Annual booster
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Dogs were recruited from Kalutara district Method
[object Object],Domestic (n=34) Stray/free roaming(n=29) Representative Sample First Day 30th Day 180th Day 360th Day Collection of blood (D0) Injected ARV Collection of blood (D30) Collection of blood (D180) Collection of blood (D360) Analyzed by RFFIT
Comparison of AB titers Results
Results * Significantly higher (<0.05) than stray population Percentage of Canines with AB titres above 0.5 IU/ml (WHO Recommendation) Group Day 0 Day 30 Day 180 Day 360 Stray/ Free roaming (n=29) 10.3 % 68.9% 89.6% 62.1% Domestic (n=34) 76.5 %* 91.2% 85.3% 82.4%
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Thank You

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Presentation riacon

  • 1. Determination of antibody titres in adult stray/free roaming and domestic canines against anti-rabies immunization by RFFIT A Preliminary report Pimburage R M S 1 , Gunatilake M 2 , Wimalaratne O 3 , Balasuriya A 4 , Perera K A D N 3 1 Deprtment of Public Health Veterinary Services, Ministry of Health 2 Department of Physiology, Faculty of Medicine, Colombo 08 3 Department of Rabies Research and Vaccine Quality control, Medical Research Institute, Colombo 08 4 Faculty of Medicine, General Sir John Kotelawala Defence University
  • 2.
  • 3.
  • 4.
  • 5. Dogs were recruited from Kalutara district Method
  • 6.
  • 7. Comparison of AB titers Results
  • 8. Results * Significantly higher (<0.05) than stray population Percentage of Canines with AB titres above 0.5 IU/ml (WHO Recommendation) Group Day 0 Day 30 Day 180 Day 360 Stray/ Free roaming (n=29) 10.3 % 68.9% 89.6% 62.1% Domestic (n=34) 76.5 %* 91.2% 85.3% 82.4%
  • 9.
  • 10.
  • 11.