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Preop Case Presentation
On Behalf of NSU- Pink
PRESENTED BY
DR. MD. ATIQUL ISLAM
MS PHASE- B
DEPARTMENT OF NEUROSURGERY, DMCH
Particulars of the patient.
 Name – Shahin Rahman
 Age – 39 years
 Sex –Male
 Handed – Right
 Address –Veramara, Kustia
 Date of Admission – 07/12/2022
Chief complaint
 Headache for 1yr
 Loss of vision for 8 months
History of present illness
According to the statement of patient , he was apparently well 1 year
back.
 Then he developed headache over the vertex, which was insidious in
onset mild to moderate in intensity, intermittent and dull aching in
nature. There was no aggravating factor but relieved by taking some
medication and sleep. Headache was not associated with nausea and
vomiting
 He also complained progressive visual disturbance, in the form of
difficulty in distant vision on left side for last 8 months. He also
complained of occasional bumping into objects, placed on lateral
aspect of his eyesight both eye
 He denies truncal obesity, moon facies or development of
hypertension or diabetes in recent times
 No history of intolerance to heat or cold, hyper-activity or
pronounced lethargy, nervousness, palpitation or tremor
 No history of enlargement of hands or feet in recent months,
change in shoe size, enlargement of front/back of the head or
jaw, history of loss of libido
 No history of anorexia, weight loss, fever, cough, chest pain,
haemoptysis and bowel bladder disturbance
Past medical/surgical History:
 Nothing significant.
Drug history:
 Paracetamol, other NSAID.
Personal history:
 Non-smoker, non-alcoholic.
Family history
 He has 2 son 1 daughter. None of his family member
has similar type of illness
Socio-economic history
 He belongs to middle class family
Allergy History
 Not allergic to known drugs or food
Immunization history
 Patient was immunized as per EPI Schedule
GENERAL EXAMINATION
 Appearance- anxious, ill looking
 Body built- Average
 Cooperative
 Decubitus- Mostly lying
 Nutritional status- Good
 Anaemia, Jaundice, Cyanosis-absent
 Clubbing-absent
 Dehydration, Oedema-absent
 Lymph node-not palpable
 Thyroid gland-not enlarged
 Pulse-76b/min
 BP-90/60mmhg
 Temperature-98oF
 Respiratory rate-18/min
GENERAL EXAMINATION
Nervous System Examination
 Higher psychic function including speech- Intact
 GCS- 15
 Gait- Normal
Systemic examination
CN-II, reveals
 Visual Acuity-
 Right- 6/6
 Left- 6/24
 Visual Field-
 Bitemporal hemianopia
 Color vision- Intact
 Fundoscopy- Normal.
Cranial nerve examination
 Examination of other cranial nerves reveals normal
 Sensory examination-
All modalities of sensation like pain, touch, temperature,
vibration & joint position are normal.
Fundal Photography
Visual Field Perimetry
Motor examination-
Upper limb Right Left
Bulk Normal Normal
Tone Normal Normal
Power (MRC grade) Root Value
Elbow flexors C5 5 5
Wrist extensors C6 5 5
Elbow extensors C7 5 5
Finger flexors C8 5 5
Finger extensors T1 5 5
Deep tendon reflexes
Biceps jerk C5,6 Normal Normal
Triceps jerk C7 Normal Normal
Supinator jerk C5,6 Normal Normal
Special tests
Hoffman’s sign Absent Absent
Lower limb Right Left
Bulk Normal Normal
Tone Normal Increased
Power (MRC grade) Root Value
Hip flexors L2 5 5
Knee extensors L3 5 5
Ankle dorsiflexors L4 5 5
Great toe extensors L5 5 5
Ankle planter flexors S1 5 5
Deep tendon reflexes
Knee jerk L3,4 Normal Normal
Ankle jerk S1,2 Normal Normal
Clonus
Knee clonus Absent Absent
Ankle clonus Absent Absent
Special tests
Plantar response Normal Normal
 Cerebellar sign- Absent.
 No Sign of meningeal irritation
 Examination of other systems reveal normal
 Sellar Suprasellar Space Occupying Lesion
Provisional Diagnosis
Investigations
MRI T1
MRI T1
MRI T2
MRI T2
Contrast MRI
Contrast MRI
FLAIR
DWI
Knosp classification
Hormone and Serum Profile
Investigation Patient Value Normal Range
Cortisol 10 μg/m ND to 46 pg/ml
GH 0.11 ng/ml 0.06 to 5 ng/ml
TSH 4.87 μIU/ml 0.35 to 5.50 μIU/ml
Prolactin 17.87 ng/ml 1.9 to 25 ng/ml
RBS 5.5 mmol/l 4.4 to 7.8 mmol/l
Non functioning Pituitry macroadenoma
Clinico-Radiological diagnosis
Operative Plan
Endoscopic endonasal transsphenoidal resection of
pituitary macroadenoma
Principles of endonasal Pituitary
Surgery
 Capitalize on Experience
 Develop a Comprehensive Understanding of the Surgical Anatomy
 Don’t: Rely on Tools Such as Neuronavigation
 Employ the Four-Handed, Binostril Technique
 Select the Anatomical Corridor Required for Complete Access
 Plan the Reconstruction Prior to the Approach and Resection
 Ensure Adequate Exposure
 Dissect Carefully with Great Respect for the Tissues
Important measures
 The endotracheal tube will be brought out from the left side
of the mouth.
 Oropharyngeal pack
 Prophylactic antibiotic
 Catheterization: per-operative monitoring
of urine output
 Hypotensive anaesthesia
Positioning
 Supine position with torso elevated 15 -20˚
 Forehead and chin lies horizontally.
 Level of head higher than chest (to improve venous return)
 Head flex 15 ̊ and rotated 10-15 ̊ towards the surgeon
Stages of surgery
 Nasal phase
 Sphenoidal phase
 Sellar phase
 Reconstruction
Nasal cavity architecture
Nasal phase
 Lateralization of Inferior turbinate
 Partial Resection of middle turbinate – Turbinectomy scissors
 Identification and lateralization of superior terbinate
 Exposure of sphenoid osteum and choana
Hadad flap
 The posterior nasal septum is disarticutlated from the rostrum of the sphenoid bone;
its posterior edge is resected with a backbiting forceps. Save this bone for later sellar
reconstruction following tumor resection.
 Bilateral instrumentation without deviation of the septum into the path of the endoscope and
increase lateral angulation and range of motion of the instruments.
Removal of posterior part of nasal septum
Sphenoid phase
Sphenoid phase
Sellar phase
(a)Bone of the sella has been removed.
(b) The blue hue seen of the cavernous and intercavernous sinuses.
(a) The dural incisions are made to avoid the intercavernous
sinus.
(b) The dural flap is reflected upward to expose the tumor.
(a) The pituitary tumor is dissected inferiorly first.
(b) Inspection for residual tumor is carried out after descent of
the diaphragma.
(a) Fibrous bands and the tumor capsule are dissected.
(b) Exposure for suprasellar tumor extension involves exposure of the
opticocarotid recess. Removal of the planum sphenoidale will increase exposure
superiorly.
(a) Doppler probes assist in determining the course of the carotid artery.
(b) The completed dissection with removal of the lateral extension of the
tumor reveals the cavernous sinus, internal carotid artery, and diaphragma
sellae.
Fascia lata graft and Fat
Reconstruction
The flap is placed over the entire closure with its vascular pedicle.
Closure
 Irrigate the nasal cavity & repositioning of the nasal
septum in the midline.
 The nasal cavity is packed with an expandable foam
sponge (Merocel) .
Complications
Peroperative
 Vascular injury: Cavernous sinus, ICA
 DI
 CSF leak
 Nerve injury: Optic nerve, optic chiasm, cavernous cranial
nerves (III, IV, VI)
 Pituitary injury
 Hypothalamic injury
 Stalk injury
Postoperative
 DI & electrolyte imbalance
 CSF rhinorrhoea
 Visual deterioration
 Infections
THANK YOU

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Pituitary Macroadenoma.pptx

  • 1. Preop Case Presentation On Behalf of NSU- Pink PRESENTED BY DR. MD. ATIQUL ISLAM MS PHASE- B DEPARTMENT OF NEUROSURGERY, DMCH
  • 2. Particulars of the patient.  Name – Shahin Rahman  Age – 39 years  Sex –Male  Handed – Right  Address –Veramara, Kustia  Date of Admission – 07/12/2022
  • 3. Chief complaint  Headache for 1yr  Loss of vision for 8 months
  • 4. History of present illness According to the statement of patient , he was apparently well 1 year back.  Then he developed headache over the vertex, which was insidious in onset mild to moderate in intensity, intermittent and dull aching in nature. There was no aggravating factor but relieved by taking some medication and sleep. Headache was not associated with nausea and vomiting
  • 5.  He also complained progressive visual disturbance, in the form of difficulty in distant vision on left side for last 8 months. He also complained of occasional bumping into objects, placed on lateral aspect of his eyesight both eye  He denies truncal obesity, moon facies or development of hypertension or diabetes in recent times  No history of intolerance to heat or cold, hyper-activity or pronounced lethargy, nervousness, palpitation or tremor
  • 6.  No history of enlargement of hands or feet in recent months, change in shoe size, enlargement of front/back of the head or jaw, history of loss of libido  No history of anorexia, weight loss, fever, cough, chest pain, haemoptysis and bowel bladder disturbance
  • 7. Past medical/surgical History:  Nothing significant. Drug history:  Paracetamol, other NSAID. Personal history:  Non-smoker, non-alcoholic.
  • 8. Family history  He has 2 son 1 daughter. None of his family member has similar type of illness Socio-economic history  He belongs to middle class family
  • 9. Allergy History  Not allergic to known drugs or food Immunization history  Patient was immunized as per EPI Schedule
  • 10. GENERAL EXAMINATION  Appearance- anxious, ill looking  Body built- Average  Cooperative  Decubitus- Mostly lying  Nutritional status- Good  Anaemia, Jaundice, Cyanosis-absent  Clubbing-absent
  • 11.  Dehydration, Oedema-absent  Lymph node-not palpable  Thyroid gland-not enlarged  Pulse-76b/min  BP-90/60mmhg  Temperature-98oF  Respiratory rate-18/min GENERAL EXAMINATION
  • 12. Nervous System Examination  Higher psychic function including speech- Intact  GCS- 15  Gait- Normal Systemic examination
  • 13. CN-II, reveals  Visual Acuity-  Right- 6/6  Left- 6/24  Visual Field-  Bitemporal hemianopia  Color vision- Intact  Fundoscopy- Normal. Cranial nerve examination
  • 14.  Examination of other cranial nerves reveals normal  Sensory examination- All modalities of sensation like pain, touch, temperature, vibration & joint position are normal.
  • 17. Motor examination- Upper limb Right Left Bulk Normal Normal Tone Normal Normal Power (MRC grade) Root Value Elbow flexors C5 5 5 Wrist extensors C6 5 5 Elbow extensors C7 5 5 Finger flexors C8 5 5 Finger extensors T1 5 5 Deep tendon reflexes Biceps jerk C5,6 Normal Normal Triceps jerk C7 Normal Normal Supinator jerk C5,6 Normal Normal Special tests Hoffman’s sign Absent Absent
  • 18. Lower limb Right Left Bulk Normal Normal Tone Normal Increased Power (MRC grade) Root Value Hip flexors L2 5 5 Knee extensors L3 5 5 Ankle dorsiflexors L4 5 5 Great toe extensors L5 5 5 Ankle planter flexors S1 5 5 Deep tendon reflexes Knee jerk L3,4 Normal Normal Ankle jerk S1,2 Normal Normal Clonus Knee clonus Absent Absent Ankle clonus Absent Absent Special tests Plantar response Normal Normal
  • 19.  Cerebellar sign- Absent.  No Sign of meningeal irritation  Examination of other systems reveal normal
  • 20.
  • 21.  Sellar Suprasellar Space Occupying Lesion Provisional Diagnosis
  • 29. FLAIR
  • 30. DWI
  • 32. Hormone and Serum Profile Investigation Patient Value Normal Range Cortisol 10 μg/m ND to 46 pg/ml GH 0.11 ng/ml 0.06 to 5 ng/ml TSH 4.87 μIU/ml 0.35 to 5.50 μIU/ml Prolactin 17.87 ng/ml 1.9 to 25 ng/ml RBS 5.5 mmol/l 4.4 to 7.8 mmol/l
  • 33.
  • 34. Non functioning Pituitry macroadenoma Clinico-Radiological diagnosis
  • 35. Operative Plan Endoscopic endonasal transsphenoidal resection of pituitary macroadenoma
  • 36. Principles of endonasal Pituitary Surgery  Capitalize on Experience  Develop a Comprehensive Understanding of the Surgical Anatomy  Don’t: Rely on Tools Such as Neuronavigation  Employ the Four-Handed, Binostril Technique  Select the Anatomical Corridor Required for Complete Access  Plan the Reconstruction Prior to the Approach and Resection  Ensure Adequate Exposure  Dissect Carefully with Great Respect for the Tissues
  • 37. Important measures  The endotracheal tube will be brought out from the left side of the mouth.  Oropharyngeal pack  Prophylactic antibiotic  Catheterization: per-operative monitoring of urine output  Hypotensive anaesthesia
  • 38. Positioning  Supine position with torso elevated 15 -20˚  Forehead and chin lies horizontally.  Level of head higher than chest (to improve venous return)  Head flex 15 ̊ and rotated 10-15 ̊ towards the surgeon
  • 39. Stages of surgery  Nasal phase  Sphenoidal phase  Sellar phase  Reconstruction
  • 42.  Lateralization of Inferior turbinate  Partial Resection of middle turbinate – Turbinectomy scissors
  • 43.  Identification and lateralization of superior terbinate  Exposure of sphenoid osteum and choana
  • 45.  The posterior nasal septum is disarticutlated from the rostrum of the sphenoid bone; its posterior edge is resected with a backbiting forceps. Save this bone for later sellar reconstruction following tumor resection.  Bilateral instrumentation without deviation of the septum into the path of the endoscope and increase lateral angulation and range of motion of the instruments. Removal of posterior part of nasal septum
  • 49. (a)Bone of the sella has been removed. (b) The blue hue seen of the cavernous and intercavernous sinuses.
  • 50. (a) The dural incisions are made to avoid the intercavernous sinus. (b) The dural flap is reflected upward to expose the tumor.
  • 51. (a) The pituitary tumor is dissected inferiorly first. (b) Inspection for residual tumor is carried out after descent of the diaphragma.
  • 52. (a) Fibrous bands and the tumor capsule are dissected. (b) Exposure for suprasellar tumor extension involves exposure of the opticocarotid recess. Removal of the planum sphenoidale will increase exposure superiorly.
  • 53. (a) Doppler probes assist in determining the course of the carotid artery. (b) The completed dissection with removal of the lateral extension of the tumor reveals the cavernous sinus, internal carotid artery, and diaphragma sellae.
  • 54. Fascia lata graft and Fat
  • 56. The flap is placed over the entire closure with its vascular pedicle.
  • 57. Closure  Irrigate the nasal cavity & repositioning of the nasal septum in the midline.  The nasal cavity is packed with an expandable foam sponge (Merocel) .
  • 59. Peroperative  Vascular injury: Cavernous sinus, ICA  DI  CSF leak  Nerve injury: Optic nerve, optic chiasm, cavernous cranial nerves (III, IV, VI)  Pituitary injury  Hypothalamic injury  Stalk injury
  • 60. Postoperative  DI & electrolyte imbalance  CSF rhinorrhoea  Visual deterioration  Infections

Editor's Notes

  1. Diffusion-weighted imaging (DWI) is a form of MR imaging based upon measuring the random Brownian motion of water molecules within a voxel of tissue. In general simplified terms, highly cellular tissues or those with cellular swelling exhibit lower diffusion coefficients.
  2. 55
  3. Fluid-attenuated inversion recovery (FLAIR) sequence that produces strong T2 weighting, suppresses the CSF signal, and minimizes contrast between gray matter and white matter.
  4. Removing of rostrum by high speed drill or Kerrison rongure. Lateral limit is medial wall of pterygoid & lateral sphenoid wall. Mucosa of the sphenoid sinus is removed for drilling and later reconstruction. Landmark- sellar prominence, medial and lateral opticocarotid recess, para sellar carotid prominence, clival recess.
  5. Eggshell bone was removed by dissector
  6. Haemostasis will be achieved with electrocautery and surgicel