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Pituitary Macroadenoma.pptx
1. Preop Case Presentation
On Behalf of NSU- Pink
PRESENTED BY
DR. MD. ATIQUL ISLAM
MS PHASE- B
DEPARTMENT OF NEUROSURGERY, DMCH
2. Particulars of the patient.
Name – Shahin Rahman
Age – 39 years
Sex –Male
Handed – Right
Address –Veramara, Kustia
Date of Admission – 07/12/2022
4. History of present illness
According to the statement of patient , he was apparently well 1 year
back.
Then he developed headache over the vertex, which was insidious in
onset mild to moderate in intensity, intermittent and dull aching in
nature. There was no aggravating factor but relieved by taking some
medication and sleep. Headache was not associated with nausea and
vomiting
5. He also complained progressive visual disturbance, in the form of
difficulty in distant vision on left side for last 8 months. He also
complained of occasional bumping into objects, placed on lateral
aspect of his eyesight both eye
He denies truncal obesity, moon facies or development of
hypertension or diabetes in recent times
No history of intolerance to heat or cold, hyper-activity or
pronounced lethargy, nervousness, palpitation or tremor
6. No history of enlargement of hands or feet in recent months,
change in shoe size, enlargement of front/back of the head or
jaw, history of loss of libido
No history of anorexia, weight loss, fever, cough, chest pain,
haemoptysis and bowel bladder disturbance
7. Past medical/surgical History:
Nothing significant.
Drug history:
Paracetamol, other NSAID.
Personal history:
Non-smoker, non-alcoholic.
8. Family history
He has 2 son 1 daughter. None of his family member
has similar type of illness
Socio-economic history
He belongs to middle class family
9. Allergy History
Not allergic to known drugs or food
Immunization history
Patient was immunized as per EPI Schedule
10. GENERAL EXAMINATION
Appearance- anxious, ill looking
Body built- Average
Cooperative
Decubitus- Mostly lying
Nutritional status- Good
Anaemia, Jaundice, Cyanosis-absent
Clubbing-absent
14. Examination of other cranial nerves reveals normal
Sensory examination-
All modalities of sensation like pain, touch, temperature,
vibration & joint position are normal.
17. Motor examination-
Upper limb Right Left
Bulk Normal Normal
Tone Normal Normal
Power (MRC grade) Root Value
Elbow flexors C5 5 5
Wrist extensors C6 5 5
Elbow extensors C7 5 5
Finger flexors C8 5 5
Finger extensors T1 5 5
Deep tendon reflexes
Biceps jerk C5,6 Normal Normal
Triceps jerk C7 Normal Normal
Supinator jerk C5,6 Normal Normal
Special tests
Hoffman’s sign Absent Absent
18. Lower limb Right Left
Bulk Normal Normal
Tone Normal Increased
Power (MRC grade) Root Value
Hip flexors L2 5 5
Knee extensors L3 5 5
Ankle dorsiflexors L4 5 5
Great toe extensors L5 5 5
Ankle planter flexors S1 5 5
Deep tendon reflexes
Knee jerk L3,4 Normal Normal
Ankle jerk S1,2 Normal Normal
Clonus
Knee clonus Absent Absent
Ankle clonus Absent Absent
Special tests
Plantar response Normal Normal
19. Cerebellar sign- Absent.
No Sign of meningeal irritation
Examination of other systems reveal normal
32. Hormone and Serum Profile
Investigation Patient Value Normal Range
Cortisol 10 μg/m ND to 46 pg/ml
GH 0.11 ng/ml 0.06 to 5 ng/ml
TSH 4.87 μIU/ml 0.35 to 5.50 μIU/ml
Prolactin 17.87 ng/ml 1.9 to 25 ng/ml
RBS 5.5 mmol/l 4.4 to 7.8 mmol/l
36. Principles of endonasal Pituitary
Surgery
Capitalize on Experience
Develop a Comprehensive Understanding of the Surgical Anatomy
Don’t: Rely on Tools Such as Neuronavigation
Employ the Four-Handed, Binostril Technique
Select the Anatomical Corridor Required for Complete Access
Plan the Reconstruction Prior to the Approach and Resection
Ensure Adequate Exposure
Dissect Carefully with Great Respect for the Tissues
37. Important measures
The endotracheal tube will be brought out from the left side
of the mouth.
Oropharyngeal pack
Prophylactic antibiotic
Catheterization: per-operative monitoring
of urine output
Hypotensive anaesthesia
38. Positioning
Supine position with torso elevated 15 -20˚
Forehead and chin lies horizontally.
Level of head higher than chest (to improve venous return)
Head flex 15 ̊ and rotated 10-15 ̊ towards the surgeon
39. Stages of surgery
Nasal phase
Sphenoidal phase
Sellar phase
Reconstruction
45. The posterior nasal septum is disarticutlated from the rostrum of the sphenoid bone;
its posterior edge is resected with a backbiting forceps. Save this bone for later sellar
reconstruction following tumor resection.
Bilateral instrumentation without deviation of the septum into the path of the endoscope and
increase lateral angulation and range of motion of the instruments.
Removal of posterior part of nasal septum
49. (a)Bone of the sella has been removed.
(b) The blue hue seen of the cavernous and intercavernous sinuses.
50. (a) The dural incisions are made to avoid the intercavernous
sinus.
(b) The dural flap is reflected upward to expose the tumor.
51. (a) The pituitary tumor is dissected inferiorly first.
(b) Inspection for residual tumor is carried out after descent of
the diaphragma.
52. (a) Fibrous bands and the tumor capsule are dissected.
(b) Exposure for suprasellar tumor extension involves exposure of the
opticocarotid recess. Removal of the planum sphenoidale will increase exposure
superiorly.
53. (a) Doppler probes assist in determining the course of the carotid artery.
(b) The completed dissection with removal of the lateral extension of the
tumor reveals the cavernous sinus, internal carotid artery, and diaphragma
sellae.
56. The flap is placed over the entire closure with its vascular pedicle.
57. Closure
Irrigate the nasal cavity & repositioning of the nasal
septum in the midline.
The nasal cavity is packed with an expandable foam
sponge (Merocel) .
Diffusion-weighted imaging (DWI) is a form of MR imaging based upon measuring the random Brownian motion of water molecules within a voxel of tissue. In general simplified terms, highly cellular tissues or those with cellular swelling exhibit lower diffusion coefficients.
55
Fluid-attenuated inversion recovery (FLAIR) sequence that produces strong T2 weighting, suppresses the CSF signal, and minimizes contrast between gray matter and white matter.
Removing of rostrum by high speed drill or Kerrison rongure.
Lateral limit is medial wall of pterygoid & lateral sphenoid wall.
Mucosa of the sphenoid sinus is removed for drilling and later reconstruction.
Landmark- sellar prominence, medial and lateral opticocarotid recess, para sellar carotid prominence, clival recess.
Eggshell bone was removed by dissector
Haemostasis will be achieved with electrocautery and surgicel