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© 2020 Journal of Family Medicine and Primary Care | Published by Wolters Kluwer ‑ Medknow	 1752
Introduction
The twenty‑first century is referred to as the century of the
biologist, and the regeneration dimension of Periodontics is
a front stage player in the script of scientific progress. One
of the most salient features in this inevitable progress is the
interdisciplinary alliance of orthodontic specialty and periodontal
regenerative surgery, which have taken traditional orthodontic
tooth movement protocols to a completely new synergism.
In 2001, the Wilcko Brothers combined the refined
corticotomy‑facilitated orthodontic technique with alveolar
augmentation and named the procedure Periodontally accelerated
osteogenic orthodontics (PAOO).[1]
Treatment of class I
malocclusions with moderate to severe crowding, Class II
malocclusions requiring expansion or extractions, and mild
class III malocclusions can be achieved with PAOO.[2]
Case Report
A 14‑year‑old male undergoing fixed orthodontic treatment for
Class II malocclusion for 1.5 years reported to the department of
periodontics at our institution [Figure 1a‑c]. The patient had an
uneventful extraction of 46 because of the presence of extensive
caries, which could not be treated with endodontic intervention
6 months back [Figure 2]. For the successful completion of
treatment was to be achieved by orthodontically repositioning 47
in the place of missing 46. As the treatment time for space closure
by second molar protraction in adults ranges from 2–3 years,
the tooth movement was to be accomplished using the PAOO
procedure. The patient had no systemic medical history and had
good oral hygiene. As the patient was a minor, the consent of the
parents was taken.
After administration of local anesthesia, crestal incisions
were given in the edentulous area of 46 along with crevicular
incisions with respect to 47 and 45 [Figure 3]. A full‑thickness
mucoperiosteal flap was reflected well beyond the
mucogingival junction exposing the buccal and lingual cortical
Periodontally accelerated osteogenic orthodontics: A
perio-ortho ambidextrous perspective
Anuj Singh Parihar1
, Sumit Narang1
, Nandini Singh2
, Anu Narang3
1
Department of Periodontics, People’s Dental Academy, Bhopal, Madhya Pradesh, 2
Bharati Vidyapeeth Dental College and
Hospital, Pune, Maharashtra, 3
Department of Conservative Dentistry, People's College of Dental Sciences and Research Centre,
Bhopal, Madhya Pradesh, India
Abstract
The interdisciplinary collaboration of periodontics and orthodontics has allowed teeth to be moved 2–3 times faster, reducing the
time required for traditional orthodontic therapy considerably. Periodontally accelerated osteogenic orthodontics (PAOO), also
known as Wilckodontics, is a combination of a selective decortication facilitated orthodontics and alveolar augmentation. With
this technique, there is no dependence on the pre‑existing alveolar volume. This case report describes the treatment of permanent
mandibular molar protraction in a 14‑year‑old patient undergoing orthodontic therapy using PAOO with piezosurgery.
Keywords: Corticotomy, bone grafts, orthodontics, osteogenic, periodontics
Case Report
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DOI:
10.4103/jfmpc.jfmpc_1055_19
Address for correspondence: Dr. Anuj Singh Parihar,
Department of Periodontics, People’s Dental Academy,
Bhopal ‑ 462 037, Madhya Pradesh, India.
E‑mail: Dr.anujparihar@gmail.com
How to cite this article: Parihar AS, Narang S, Singh N,
Narang A. Periodontally accelerated osteogenic orthodontics: A perio-
ortho ambidextrous perspective. J Family Med Prim Care 2020;9:1752-6.
This is an open access journal, and articles are distributed under the terms of the Creative
Commons Attribution‑NonCommercial‑ShareAlike 4.0 License, which allows others to
remix, tweak, and build upon the work non‑commercially, as long as appropriate credit is
given and the new creations are licensed under the identical terms.
For reprints contact: reprints@medknow.com
Received: 24-11-2019		 Revised: 13-02-2020
Accepted: 20-02-2020		 Published: 26-03-2020
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Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique
Journal of Family Medicine and Primary Care	 1753	 Volume 9 : Issue 3 : March 2020
plates [Figure 4]. Vertical corticotomies of approximately
0.5 mm deep were created using the peizosurgical insert no.
OT2 [Figure 5] on the buccal and lingual cortical plates, mesial,
and distal aspects of 47 [Figures 6 and 7]. Decortication was
performed using a round carbide bur no. 8 on the buccal
and lingual aspect with respect to 47 and the edentulous
area of 46 with a depth of approximately 0.5 mm into the
cortical bone [Figure  8]. These corticotomies were deep
enough to enter the cancellous aspect of the bone after
the corticotomies, and bone grafting was performed using
demineralized freeze‑dried bone allograft  (DFDBA) on
the buccal and lingual aspects where the decortication was
performed [Figure 9]. Primary closure was achieved using 3–0
silk sutures [Figure 10]. Orthodontic treatment commenced
15  days postsurgery with the application of E chain and
Figure 2: Edentulous space at 46
Figure 3: Crestal and crevicular incision given Figure 4: Full‑thickness mucoperiosteal flap reflected
Figure 6: Peizosurgical unitFigure 5: Completion of vertical corticotomies
Figure 1: (a): Frontal view (b): Right Lateral view (c): Left Lateral view
cb
a
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Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique
Journal of Family Medicine and Primary Care	 1754	 Volume 9 : Issue 3 : March 2020
lingual buttons and continuous forces were applied to enable
the tooth movement [Figure 11].
The follow‑up at months 3 and 6 showed substantial mesialization
of 47 with the closure of the space [Figure 12]. The intraoral
periapical radiographs at 3 and 6 months showed signs of active
tooth movement [Figure 13]. Complete closure of space was
achieved at 10 months [Figure 14a and 14b].
Discussion
The PAOO procedure is based on the principle of regional
acceleratory phenomenon (RAP).[3]
The duration of RAP
depends on the type of tissue and usually lasts about 4 months
Figure 8: Decortication of the buccal and lingual cortical plates using
micromotor and round carbide bur
Figure 9: Placement of DFDBA bone graft
Figure  11: Application of E chain with lingual buttons 2 weeks
postsurgery
Figure 10: Sutures placed
Figure 12: Reduction of edentulous space 6 months postsurgery
Figure 7: Peizosurgical insert kit
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Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique
Journal of Family Medicine and Primary Care	 1755	 Volume 9 : Issue 3 : March 2020
in human bone.[3]
This physical process causes bone healing
to occur 10–50 times faster than normal bone turnover.
Köle reported no periodontal pocket formation.[4]
Bhattacharya
et al. compared the treatment time for the closure of extraction
space between conventional orthodontic tooth movement and
corticotomy assisted and evaluated the alveolar bone thickness
before and after corticotomy procedure using CT scan. They
concluded that alveolar corticotomies not only accelerated
the orthodontic treatment but also provided the advantage
of increased alveolar width to support the teeth as evaluated
based on the CT scan analysis.[5]
Wilcko T, Wilkco W, Bissada F
conducted an evidence‑based analysis of PAOO and stated that
this treatment procedure allows conventional orthodontic tooth
movement (OTM) 300% to 400% faster, increases the envelope of
movement two‑ to three‑fold and alveolar augmentation increases
alveolar volume providing an alternative to bicuspid extraction.[6]
Piezosurgery is a relatively modern technique for osteotomy and
osteoplasty utilizing ultrasonic vibration. There are various benefits
of combining the modified corticotomy‑facilitated orthodontics
with alveolar augmentation. The most evident is that there is no
need to rely on the pre‑existing alveolar volume and shape solely.[7]
Dr.  Wilcko suggested that analgesics like ibuprofen are
not recommended postoperatively as they are nonsteroidal
anti‑inflammatory drugs (NSAIDs). NSAIDs can actually interfere
with the production of prostaglandin hormone in the body and
can retard the bone growth process, which is critical to PAOO.[8]
Besides, NSAIDs gave during the first 24 h following trauma
cause inhibition of clotting. Therefore, ideally, one should not be
prescribed NSAIDs before or after undergoing PAOO surgery.[9]
The PAOO procedure does have its advantages and disadvantages.
The advantages include:
1.	 Lesser time than traditional orthodontics
2.	 Less likelihood of root resorption.
3.	 The history of relapse has been meager.
The disadvantages are:
1.	 Mildly invasive surgical procedure, and usually like all
surgeries, it has a risk of some pain, swelling, and the
possibility of infection.[10]
2.	 Medically compromised cases on long term intake of
NSAIDs cannot be treated with this technique.[11]
3.	 Class III malocclusion cases cannot be treated with this
approach.[12]
In spite of these drawbacks, the advantages of less treatment
time and low relapse rates vastly supersede the disadvantages of
this procedure.[13,14]
Conclusion
The fact that the teeth can be moved more rapidly, thus
resulting in shortened treatment times, is certainly advantageous
in reducing apprehension among the adolescent population
regarding the period of the traditional orthodontic treatment.
The PAOO technique can correct malocclusion in most patients
within 3 to 10 months. This procedure puts orthodontics on
a fast track by incorporating changes in the structure of the
surrounding bone to accompany the repositioning of the teeth.
The PAOO technique requires the application of numerous
modified diagnostic and treatment parameters, which once
mastered, make it a powerful new treatment option to offer the
patients.
Declaration of patient consent
The authors certify that they have obtained all appropriate
patient consent forms. In the form, the patient (s) has/have
given his/her/their consent for his/her/their images and other
clinical information to be reported in the journal. The patients
understand that their names and initials will not be published and
due efforts will be made to conceal their identity, but anonymity
cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
Figure 13: IOPA after 6 months
Figure  14: (a): Closure of edentulous space 10 months
postsurgery (Right lateral view) (b): Closure of edentulous space
10 months postsurgery (Buccal space closed)
ba
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Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique
Journal of Family Medicine and Primary Care	 1756	 Volume 9 : Issue 3 : March 2020
References
1. 	 Pathak TS, Kini V, Kanagotagi S, Balasubramanian K,
Gupta H. Wilckodontics. J Contemp Dent 2013;3:15‑9.
2.	 Wilcko T, Wilcko W. An evidence‑based analysis of
periodontally accelerated orthodontic and osteogenic
techniques: A synthesis of scientific perspectives semin.
Orthod 2008;14:305‑16.
3.	 Frost HM. The biology of fracture healing: An overview for
clinicians. Part II. Clin Orthop Rel Res 1989;248:283‑9.
4.	 Köle H. Surgical operations of the alveolar ridge to correct
occlusal abnormalities. Oral Surg Oral Med Oral Pathol
1989;12:515‑29.
5.	 Bhattacharya P, Bhattacharya H, Anjum A, Bhandari R,
Agarwal DK, Gupta A, et al. Assessment of corticotomy
facilitated tooth movement and changes in bone
thickness – A CT scan study. J Clin Diagn Res 2014;8:26‑30.
6.	 Sheshan H. Piezosurgery in periodontology and oral
implantology. J Indian Soc Periodontol 2009;13:155‑6.
7.	 Murphy KG, Wilcko MT, Wilcko WM, Ferguson DJ. Periodontal
accelerated osteogenic orthodontics: A description of the
surgical technique. J Oral Maxillofac Surg 2009;67:2160‑6.
8.	 Nazzal AM, Trojan TM, Green M. Uprighting and
periodontally accelerated osteogenic orthodontics as an
alternative to surgical crown lengthening. J Clin Orthod
2016;50:507‑11.
9.	 Chackartchi T, Barkana I, Klinger A. Alveolar bone
morphology following periodontally accelerated osteogenic
orthodontics: A clinical and radiographic analysis. Int J
Periodontics Restorative Dent 2017;37:203‑8.
10.	 Campbell JH. Uprighting and periodontally accelerated
osteogenic orthodontics. J Oral Maxillofac Surg 2017;75:6.
11.	 Miyamoto T, Lang M, Khan S, Kumagai K, Nunn ME. The
clinical efficacy of deproteinized bovine bone mineral with
10% collagen in conjunction with localized piezosurgical
decortication enhanced orthodontics: A prospective
observational study. J Periodontol 2019;90:1106‑15.
12.	 Soltani L, Loomer PM, Chaar EE. A novel approach in
periodontally accelerated osteogenic orthodontics (PAOO):
A case report. Clin Adv Periodontics 2019;9:110‑4.
13.	 AlHammadi HA, Wilcho MT, Ferguson DJ. Severe mandibular
crowding treated with nonextraction periodontally
accelerated osteogenic orthodontics. Int J Periodontics
Restorative Dent 2019;39:e188‑94.
14.	 Jing WD, Xu L, Xu X, Hou JX, Li XT. Association
between periodontal biotype and clinical parameters:
A cross‑sectional study in patients with skeletal class III
malocclusion. Chin J Dent Res 2019;22:9‑19.
[Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]

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Periodontally accelerated osteogenic orthodontics: A perio-ortho ambidextrous perspective

  • 1. © 2020 Journal of Family Medicine and Primary Care | Published by Wolters Kluwer ‑ Medknow 1752 Introduction The twenty‑first century is referred to as the century of the biologist, and the regeneration dimension of Periodontics is a front stage player in the script of scientific progress. One of the most salient features in this inevitable progress is the interdisciplinary alliance of orthodontic specialty and periodontal regenerative surgery, which have taken traditional orthodontic tooth movement protocols to a completely new synergism. In 2001, the Wilcko Brothers combined the refined corticotomy‑facilitated orthodontic technique with alveolar augmentation and named the procedure Periodontally accelerated osteogenic orthodontics (PAOO).[1] Treatment of class I malocclusions with moderate to severe crowding, Class II malocclusions requiring expansion or extractions, and mild class III malocclusions can be achieved with PAOO.[2] Case Report A 14‑year‑old male undergoing fixed orthodontic treatment for Class II malocclusion for 1.5 years reported to the department of periodontics at our institution [Figure 1a‑c]. The patient had an uneventful extraction of 46 because of the presence of extensive caries, which could not be treated with endodontic intervention 6 months back [Figure 2]. For the successful completion of treatment was to be achieved by orthodontically repositioning 47 in the place of missing 46. As the treatment time for space closure by second molar protraction in adults ranges from 2–3 years, the tooth movement was to be accomplished using the PAOO procedure. The patient had no systemic medical history and had good oral hygiene. As the patient was a minor, the consent of the parents was taken. After administration of local anesthesia, crestal incisions were given in the edentulous area of 46 along with crevicular incisions with respect to 47 and 45 [Figure 3]. A full‑thickness mucoperiosteal flap was reflected well beyond the mucogingival junction exposing the buccal and lingual cortical Periodontally accelerated osteogenic orthodontics: A perio-ortho ambidextrous perspective Anuj Singh Parihar1 , Sumit Narang1 , Nandini Singh2 , Anu Narang3 1 Department of Periodontics, People’s Dental Academy, Bhopal, Madhya Pradesh, 2 Bharati Vidyapeeth Dental College and Hospital, Pune, Maharashtra, 3 Department of Conservative Dentistry, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India Abstract The interdisciplinary collaboration of periodontics and orthodontics has allowed teeth to be moved 2–3 times faster, reducing the time required for traditional orthodontic therapy considerably. Periodontally accelerated osteogenic orthodontics (PAOO), also known as Wilckodontics, is a combination of a selective decortication facilitated orthodontics and alveolar augmentation. With this technique, there is no dependence on the pre‑existing alveolar volume. This case report describes the treatment of permanent mandibular molar protraction in a 14‑year‑old patient undergoing orthodontic therapy using PAOO with piezosurgery. Keywords: Corticotomy, bone grafts, orthodontics, osteogenic, periodontics Case Report Access this article online Quick Response Code: Website: www.jfmpc.com DOI: 10.4103/jfmpc.jfmpc_1055_19 Address for correspondence: Dr. Anuj Singh Parihar, Department of Periodontics, People’s Dental Academy, Bhopal ‑ 462 037, Madhya Pradesh, India. E‑mail: Dr.anujparihar@gmail.com How to cite this article: Parihar AS, Narang S, Singh N, Narang A. Periodontally accelerated osteogenic orthodontics: A perio- ortho ambidextrous perspective. J Family Med Prim Care 2020;9:1752-6. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‑commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. For reprints contact: reprints@medknow.com Received: 24-11-2019 Revised: 13-02-2020 Accepted: 20-02-2020 Published: 26-03-2020 [Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]
  • 2. Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique Journal of Family Medicine and Primary Care 1753 Volume 9 : Issue 3 : March 2020 plates [Figure 4]. Vertical corticotomies of approximately 0.5 mm deep were created using the peizosurgical insert no. OT2 [Figure 5] on the buccal and lingual cortical plates, mesial, and distal aspects of 47 [Figures 6 and 7]. Decortication was performed using a round carbide bur no. 8 on the buccal and lingual aspect with respect to 47 and the edentulous area of 46 with a depth of approximately 0.5 mm into the cortical bone [Figure  8]. These corticotomies were deep enough to enter the cancellous aspect of the bone after the corticotomies, and bone grafting was performed using demineralized freeze‑dried bone allograft  (DFDBA) on the buccal and lingual aspects where the decortication was performed [Figure 9]. Primary closure was achieved using 3–0 silk sutures [Figure 10]. Orthodontic treatment commenced 15  days postsurgery with the application of E chain and Figure 2: Edentulous space at 46 Figure 3: Crestal and crevicular incision given Figure 4: Full‑thickness mucoperiosteal flap reflected Figure 6: Peizosurgical unitFigure 5: Completion of vertical corticotomies Figure 1: (a): Frontal view (b): Right Lateral view (c): Left Lateral view cb a [Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]
  • 3. Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique Journal of Family Medicine and Primary Care 1754 Volume 9 : Issue 3 : March 2020 lingual buttons and continuous forces were applied to enable the tooth movement [Figure 11]. The follow‑up at months 3 and 6 showed substantial mesialization of 47 with the closure of the space [Figure 12]. The intraoral periapical radiographs at 3 and 6 months showed signs of active tooth movement [Figure 13]. Complete closure of space was achieved at 10 months [Figure 14a and 14b]. Discussion The PAOO procedure is based on the principle of regional acceleratory phenomenon (RAP).[3] The duration of RAP depends on the type of tissue and usually lasts about 4 months Figure 8: Decortication of the buccal and lingual cortical plates using micromotor and round carbide bur Figure 9: Placement of DFDBA bone graft Figure  11: Application of E chain with lingual buttons 2 weeks postsurgery Figure 10: Sutures placed Figure 12: Reduction of edentulous space 6 months postsurgery Figure 7: Peizosurgical insert kit [Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]
  • 4. Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique Journal of Family Medicine and Primary Care 1755 Volume 9 : Issue 3 : March 2020 in human bone.[3] This physical process causes bone healing to occur 10–50 times faster than normal bone turnover. Köle reported no periodontal pocket formation.[4] Bhattacharya et al. compared the treatment time for the closure of extraction space between conventional orthodontic tooth movement and corticotomy assisted and evaluated the alveolar bone thickness before and after corticotomy procedure using CT scan. They concluded that alveolar corticotomies not only accelerated the orthodontic treatment but also provided the advantage of increased alveolar width to support the teeth as evaluated based on the CT scan analysis.[5] Wilcko T, Wilkco W, Bissada F conducted an evidence‑based analysis of PAOO and stated that this treatment procedure allows conventional orthodontic tooth movement (OTM) 300% to 400% faster, increases the envelope of movement two‑ to three‑fold and alveolar augmentation increases alveolar volume providing an alternative to bicuspid extraction.[6] Piezosurgery is a relatively modern technique for osteotomy and osteoplasty utilizing ultrasonic vibration. There are various benefits of combining the modified corticotomy‑facilitated orthodontics with alveolar augmentation. The most evident is that there is no need to rely on the pre‑existing alveolar volume and shape solely.[7] Dr.  Wilcko suggested that analgesics like ibuprofen are not recommended postoperatively as they are nonsteroidal anti‑inflammatory drugs (NSAIDs). NSAIDs can actually interfere with the production of prostaglandin hormone in the body and can retard the bone growth process, which is critical to PAOO.[8] Besides, NSAIDs gave during the first 24 h following trauma cause inhibition of clotting. Therefore, ideally, one should not be prescribed NSAIDs before or after undergoing PAOO surgery.[9] The PAOO procedure does have its advantages and disadvantages. The advantages include: 1. Lesser time than traditional orthodontics 2. Less likelihood of root resorption. 3. The history of relapse has been meager. The disadvantages are: 1. Mildly invasive surgical procedure, and usually like all surgeries, it has a risk of some pain, swelling, and the possibility of infection.[10] 2. Medically compromised cases on long term intake of NSAIDs cannot be treated with this technique.[11] 3. Class III malocclusion cases cannot be treated with this approach.[12] In spite of these drawbacks, the advantages of less treatment time and low relapse rates vastly supersede the disadvantages of this procedure.[13,14] Conclusion The fact that the teeth can be moved more rapidly, thus resulting in shortened treatment times, is certainly advantageous in reducing apprehension among the adolescent population regarding the period of the traditional orthodontic treatment. The PAOO technique can correct malocclusion in most patients within 3 to 10 months. This procedure puts orthodontics on a fast track by incorporating changes in the structure of the surrounding bone to accompany the repositioning of the teeth. The PAOO technique requires the application of numerous modified diagnostic and treatment parameters, which once mastered, make it a powerful new treatment option to offer the patients. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient (s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest. Figure 13: IOPA after 6 months Figure  14: (a): Closure of edentulous space 10 months postsurgery (Right lateral view) (b): Closure of edentulous space 10 months postsurgery (Buccal space closed) ba [Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]
  • 5. Parihar, et al.: Rapid Mandibular Molar Protraction Using PAOO Technique Journal of Family Medicine and Primary Care 1756 Volume 9 : Issue 3 : March 2020 References 1. Pathak TS, Kini V, Kanagotagi S, Balasubramanian K, Gupta H. Wilckodontics. J Contemp Dent 2013;3:15‑9. 2. Wilcko T, Wilcko W. An evidence‑based analysis of periodontally accelerated orthodontic and osteogenic techniques: A synthesis of scientific perspectives semin. Orthod 2008;14:305‑16. 3. Frost HM. The biology of fracture healing: An overview for clinicians. Part II. Clin Orthop Rel Res 1989;248:283‑9. 4. Köle H. Surgical operations of the alveolar ridge to correct occlusal abnormalities. Oral Surg Oral Med Oral Pathol 1989;12:515‑29. 5. Bhattacharya P, Bhattacharya H, Anjum A, Bhandari R, Agarwal DK, Gupta A, et al. Assessment of corticotomy facilitated tooth movement and changes in bone thickness – A CT scan study. J Clin Diagn Res 2014;8:26‑30. 6. Sheshan H. Piezosurgery in periodontology and oral implantology. J Indian Soc Periodontol 2009;13:155‑6. 7. Murphy KG, Wilcko MT, Wilcko WM, Ferguson DJ. Periodontal accelerated osteogenic orthodontics: A description of the surgical technique. J Oral Maxillofac Surg 2009;67:2160‑6. 8. Nazzal AM, Trojan TM, Green M. Uprighting and periodontally accelerated osteogenic orthodontics as an alternative to surgical crown lengthening. J Clin Orthod 2016;50:507‑11. 9. Chackartchi T, Barkana I, Klinger A. Alveolar bone morphology following periodontally accelerated osteogenic orthodontics: A clinical and radiographic analysis. Int J Periodontics Restorative Dent 2017;37:203‑8. 10. Campbell JH. Uprighting and periodontally accelerated osteogenic orthodontics. J Oral Maxillofac Surg 2017;75:6. 11. Miyamoto T, Lang M, Khan S, Kumagai K, Nunn ME. The clinical efficacy of deproteinized bovine bone mineral with 10% collagen in conjunction with localized piezosurgical decortication enhanced orthodontics: A prospective observational study. J Periodontol 2019;90:1106‑15. 12. Soltani L, Loomer PM, Chaar EE. A novel approach in periodontally accelerated osteogenic orthodontics (PAOO): A case report. Clin Adv Periodontics 2019;9:110‑4. 13. AlHammadi HA, Wilcho MT, Ferguson DJ. Severe mandibular crowding treated with nonextraction periodontally accelerated osteogenic orthodontics. Int J Periodontics Restorative Dent 2019;39:e188‑94. 14. Jing WD, Xu L, Xu X, Hou JX, Li XT. Association between periodontal biotype and clinical parameters: A cross‑sectional study in patients with skeletal class III malocclusion. Chin J Dent Res 2019;22:9‑19. [Downloaded free from http://www.jfmpc.com on Thursday, March 26, 2020, IP: 27.56.250.96]