The document discusses the cost advantages of adequate acute pain management using non-opioid options such as intravenous paracetamol compared to opioid-related adverse events from opioids or gastrointestinal adverse events from NSAIDs. It provides several studies that have shown intravenous paracetamol to be effective for acute pain management after various surgeries and procedures while reducing costs associated with adverse events from alternative pain medications.

1. Cost Advantage of adequate Acute Pain Management:
Cost
effectiveness and cost benefit ratio of acute pain management.pdf
Cost of Opioid Related Adverse Events & NSAID Related GI adverse event in
Surgical Patients:
Cost of Cost of
Opioid-Related Adverse Drug Events.pdf
prescribed NSAID.pdf
NSAIDS Limitations:
CHF CV risk NSAIDS GI Delayed Bone
Healing
Cost Advantages of Opioid Sparing Techniques
Economic impact
of Opoids on POPM
Efficacy of Perfalgan
Peduto.pdf The Intravenous Oscier 2008 Efficacy and non opoid
Morphine-Sparing Effect of Propacetamol in orthopaedic postoperative pain.pdf intravenous.pdf
Paracetamol.pdf (Raff) (2).pdf tolerability of ready-to-use
options.pdf
Cardiac Surgery
Intravenous
paracetamol as adjunctive treatment for postoperative pain after cardiac surgery.pdf
Cesarean Section
(Vs Ibuprofen)
Intravenous Gynaec Surgery
acetaminophen vs Vs Ketorolac.pdf combination with morphine PCIA after Cesarean delivery.pdf
oral ibuprofen in

2. Spinal Surgery
Intravenous
Administration of Propacetamol Reduces.pdf
Efficacy Vs Diclofenac/NSAIDs
HYNES Hyllested
Vs Small Volume Paracetamol
Vs small vol
Paracetamol
Bioequivalence with Propacetamol
Bioequivalence
study
Enquiry Copy/Protocol
Protocol &
Enquiry.pdf
Updates
Paracetamol.pdf