Paul Contris discusses key considerations for business owners when choosing an entity structure such as sole proprietorship, LLC, or corporation. He recommends consulting with a CPA or attorney and notes an LLC provides liability protections like a corporation but avoids double taxation. Paul also emphasizes the importance of an entrepreneur having a determined mindset to persevere through challenges and not give up too early in the face of setbacks. He advises entrepreneurs to regularly evaluate their priorities and focus on completing critical tasks to achieve their goals.