The document describes FlowKeepers, a device developed to prevent circulatory ailments like deep vein thrombosis (DVT) and pulmonary embolism (PE). It uses electric muscle stimulation of the calves to improve blood flow and reduce swelling. Clinical studies showed it significantly reduced leg swelling and improved blood oxygen levels. The device is FDA approved as a powered muscle stimulator to increase blood circulation and prevent blood clots after surgery. It provides an alternative to medication for thrombo-prophylaxis for patients at risk of DVT and PE.

1. FlowKeepers  Device for Preventing Circulatory Ailments Patented, developed and owned by Amiram Katz, MD,

5. The Problem (PE):

8. The Problem (VTE): American College of Chest Physicians

9. The Problem - VTE

10. The Problem - VTE

13. The Problem : Prolong Travels in Tight Seats

15. Our Solution:

19. Our Solution: D-preVenT™ (disposable non-woven wrap for hospital environment)

20. Our Solution: FlowKeepers ® (Durable structure for prolonged use)

21. FlowKeepers ® - Next Generation

22. FlowKeepers ® - Next Generation ( With reusable cuff)

23. How does it work?

26. A Patient’s Story “ July 19, 2000, I had my first operation due to blood clot in my leg. I needed a second operation, but my leg and ankle were too swollen for surgery. About July 26th, I received a FlowKeeprs and used it about seven or eight hours a day. It helped to reduce the swelling in my ankle from 27.5 to under 24cm in circumference in about five days and I could proceed with my surgery. About two weeks after my second operation, my leg got swollen and painful again. Around August 8th, I was able to use the FlowKeepers again when my surgery wound closed. It helped to keep the swelling down and reduce pain so I was able to walk around. It reduces my need for pain medications and I am still using it for 5-6 hours a day. Today, one year later, if I do not use FlowKeepers for one or two days, I notice that by the end of the day, the swelling and pain has returned.” Geza Toth Fairfield, Connecticut

27. Amiram, The FlowKeepers device worked like a charm! It worked flawlessly the entire (flight) duration of my recent trips to Spain and Calgary. It provided great relief as my ankles were not swollen at all. A true test of its effectiveness! Even while sleeping, the device is at work. All I am required to do is turn it on and off and the device does the rest. Remarkable!! I continue to read with great interest the best advice to combat this dreaded ailment ('Economy Class Syndrome') but am now more than confident that you have a winner. I have recommended this product to all of the travelers in my office. Louis A. Sorrentino III, Vice President – SH&E Safety Practice Managing Director, Internal Evaluation Program, Flight Safety Foundation

29. Pacemakers/ Internal Defibrillators Safety