The document summarizes a team's final project presentation for a medical device startup called MammOptics. The team includes four members with engineering and business backgrounds working to develop a non-invasive, non-radiative breast cancer detection technology using optical spectroscopy. The presentation covers the initial technology and business model hypotheses, testing the value proposition with hospitals and doctors, and outlines the steps needed for product development, clinical trials, reimbursement, and company financing.
Aqua Partners LLC is a global life science consulting firm that has been operating since 1983. They help life science companies access technology, products, partnerships, and capital worldwide. Their team of professionals have expertise in areas such as M&A, strategic partnerships, licensing, clinical development, and venture investing. Aqua Partners provides strategic advisory, valuation, business development, market research, and M&A services to clients in the life science industry globally.
Four s fortnightly pharma health track 23th january - 5th febuary 2012Four-S
The document is a newsletter on the Indian healthcare industry from Four-S Services covering the period of January 23rd to February 5th, 2011. It discusses positive quarterly results for major healthcare companies in India with 28% year-over-year revenue growth. It also summarizes Dr. Reddy's Laboratories quarterly results with an 87.8% increase in net profit. The newsletter provides updates on private equity investment activity, mergers and acquisitions, regulatory news, and upcoming events in the healthcare sector.
Osage University Partners has had a productive fall, completing seven new investments in 2021 and bringing their portfolio to 16 companies. Their sector diversification strategy provided stability during difficulties in the life science and cleantech sectors. They remain cautiously optimistic for 2012 despite expecting a modest year. Their most recent investments include companies developing clinical trial software, intravenous access systems, preterm birth diagnostics, and oncology therapies targeting protein degradation pathways.
Fisher Scientific is a leading provider of products and services to the scientific community. In 2005, Fisher had revenues of $5.6 billion and approximately 19,500 employees worldwide. Fisher facilitates scientific discovery by supplying researchers and clinicians with the tools they need to enhance and prolong life. Key accomplishments in 2005 included strategic acquisitions that expanded Fisher's offerings in areas like biopharma services and life sciences, as well as operational initiatives that increased cost savings and production capabilities. Fisher is well-positioned for continued growth by meeting the evolving needs of customers in research, healthcare, and drug development.
Fisher Scientific is a leading provider of products and services to scientific researchers around the world. In 2005, Fisher had revenues of $5.6 billion and approximately 19,500 employees worldwide. The company facilitates scientific discovery by supplying researchers with over 600,000 products and services. Fisher aims to make its 350,000 customers more efficient and effective through its integrated supply chain and sales/marketing capabilities.
According to the website Investopedia, venture capital is a kind of private equity funding that is given by investors to new enterprises and small businesses that the investors feel have the potential for long-term development. In general, it is derived from wealthy investors, investment banks, and many other financial entities.
Transcell Biolife is a biobanking company founded by Dr. S Dravida to realize her vision of facilitating next-generation medicine. The company started in 2011 with its first product, ScellCare, a stem cell storage service, and has since expanded its offerings. Transcell Biolife aims to become a leading Asian biobank through organic growth and partnerships. Its stored biosamples and data will enable applications in areas like personalized medicine, clinical trials, and drug discovery. Under Dr. Dravida's leadership, the company is well-positioned to realize its goal of becoming the largest global biobank facilitating novel therapies.
The document summarizes a team's final project presentation for a medical device startup called MammOptics. The team includes four members with engineering and business backgrounds working to develop a non-invasive, non-radiative breast cancer detection technology using optical spectroscopy. The presentation covers the initial technology and business model hypotheses, testing the value proposition with hospitals and doctors, and outlines the steps needed for product development, clinical trials, reimbursement, and company financing.
Aqua Partners LLC is a global life science consulting firm that has been operating since 1983. They help life science companies access technology, products, partnerships, and capital worldwide. Their team of professionals have expertise in areas such as M&A, strategic partnerships, licensing, clinical development, and venture investing. Aqua Partners provides strategic advisory, valuation, business development, market research, and M&A services to clients in the life science industry globally.
Four s fortnightly pharma health track 23th january - 5th febuary 2012Four-S
The document is a newsletter on the Indian healthcare industry from Four-S Services covering the period of January 23rd to February 5th, 2011. It discusses positive quarterly results for major healthcare companies in India with 28% year-over-year revenue growth. It also summarizes Dr. Reddy's Laboratories quarterly results with an 87.8% increase in net profit. The newsletter provides updates on private equity investment activity, mergers and acquisitions, regulatory news, and upcoming events in the healthcare sector.
Osage University Partners has had a productive fall, completing seven new investments in 2021 and bringing their portfolio to 16 companies. Their sector diversification strategy provided stability during difficulties in the life science and cleantech sectors. They remain cautiously optimistic for 2012 despite expecting a modest year. Their most recent investments include companies developing clinical trial software, intravenous access systems, preterm birth diagnostics, and oncology therapies targeting protein degradation pathways.
Fisher Scientific is a leading provider of products and services to the scientific community. In 2005, Fisher had revenues of $5.6 billion and approximately 19,500 employees worldwide. Fisher facilitates scientific discovery by supplying researchers and clinicians with the tools they need to enhance and prolong life. Key accomplishments in 2005 included strategic acquisitions that expanded Fisher's offerings in areas like biopharma services and life sciences, as well as operational initiatives that increased cost savings and production capabilities. Fisher is well-positioned for continued growth by meeting the evolving needs of customers in research, healthcare, and drug development.
Fisher Scientific is a leading provider of products and services to scientific researchers around the world. In 2005, Fisher had revenues of $5.6 billion and approximately 19,500 employees worldwide. The company facilitates scientific discovery by supplying researchers with over 600,000 products and services. Fisher aims to make its 350,000 customers more efficient and effective through its integrated supply chain and sales/marketing capabilities.
According to the website Investopedia, venture capital is a kind of private equity funding that is given by investors to new enterprises and small businesses that the investors feel have the potential for long-term development. In general, it is derived from wealthy investors, investment banks, and many other financial entities.
Transcell Biolife is a biobanking company founded by Dr. S Dravida to realize her vision of facilitating next-generation medicine. The company started in 2011 with its first product, ScellCare, a stem cell storage service, and has since expanded its offerings. Transcell Biolife aims to become a leading Asian biobank through organic growth and partnerships. Its stored biosamples and data will enable applications in areas like personalized medicine, clinical trials, and drug discovery. Under Dr. Dravida's leadership, the company is well-positioned to realize its goal of becoming the largest global biobank facilitating novel therapies.
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The New Orleans BioInnovation Center is a $48 million facility that partners with LSUHSC and Tulane to support the commercialization of biotechnologies in the region. It provides lab space, funding assistance, and business programming to 50 technology companies. Examples include NuMe Health, which is developing prebiotics for health conditions, and MiniVax, which received an NIH grant for vaccine development. The Center aims to continue growing the entrepreneurial culture and research base in the region while addressing challenges around workforce, capital, and retaining startup companies.
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2) They have partnered with Takeda to develop an enzyme to treat a genetic disease, exceeding expectations, and are developing platforms for antibodies, gene editing, and gene optimization.
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The Southern California Consortium for Technology and Innovation in Pediatrics (CTIP) is one of seven FDA-funded pediatric device consortia working to develop medical devices for children. CTIP engages clinicians, engineers, entrepreneurs and others in developing pediatric technologies through events like Med-Innovation Rounds and symposiums. They provide support to 35 distinct pediatric device projects in their first year. To convince industry partners of opportunities in pediatrics, CTIP clearly defines projects' value propositions and market potential through due diligence. Their strategy pairs entrepreneurs with domain experts to advance technologies for children.
This document provides an overview of Kuwait Life Sciences Company (KLSC) and its subsidiaries which were established to stimulate the life sciences sector in the Middle East and North Africa region. KLSC is fully owned by NTEC, the technology transfer arm of the Kuwait Investment Authority. It has established five platform companies focused on pharmaceutical commercialization, medical devices, clinical research, healthcare training, and active pharmaceutical ingredients. The platforms work with world-class partners and have expanded operations across the MENA region since 2010. KLSC also invests in healthcare and life sciences funds and companies internationally.
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Osage University Partners Newsletter: December 2011
1. 50 Monument Road
Bala Cynwyd, PA 19004
484.434.2255—T
484.434.2256—F
www.osagepartners.com
December 2011
Dear Colleagues and Friends,
Osage University Partners has had a busy and productive fall, closing on four new investments, with a
fifth in final diligence. In total, the Fund will have completed seven new investments in 2011, which
brings our portfolio to 16 companies. The pickup in investment pace is a welcomed surprise, and whether
this increased activity is a momentary blip or a sustainable pickup is unknown.
Over the past year, our sector diversification strategy has provided ballast for our Fund during a time
when both the life science and cleantech sectors faced significant headwinds. Life science venture firms
continue to shrink or disappear, leaving a reduced pool of capital available for early stage investments.
We have also seen sector rotation away from capital intense cleantech investments by some VC’s.
However, as noted in several recent blog posts, there have been positive trends in M&A and IPO activity,
and corporate investors across multiple sectors have become quite active.
Presently, we still expect 2012 to be a modest year in terms of financing activity, but we are encouraged
by the recent level of investment activity and remain cautiously optimistic.
New Investments
Our most recent investments are listed below and represent a wide breadth of industry sectors (healthcare
services, medical devices, diagnostics and therapeutics) and company development stages (Series A
through Series C).
• Clinipace Worldwide is a contract resource organization (CRO) that has developed a proprietary
on-demand software platform based on technology from the University of Florida to more
efficiently manage Phase I-IV clinical trials. Operating in seven countries, Clinipace serves small
and medium-sized biopharmaceutical and medical device companies, as well as academic
medical centers. The company’s Series C financing round was led by Morgan Stanley Venture
Partners, with participation from existing investor Hatteras Venture Partners. Osage participated
in this oversubscribed round through its partnership with the University of Florida.
• Tangent Medical is a development stage medical device company from the University of
Michigan that has designed a novel peripheral intravenous (PIV) access system to overcome
problems associated with conventional PIV fluid delivery systems. Through its partnership with
the University of Michigan, Osage invested in this highly sought-after Series A round alongside
lead investors Arboretum Ventures and Flagship Ventures.
• Sera Prognostics is developing a molecular diagnostic to assess the risk of preterm birth. The
company has licensed novel biomarkers from Brigham Young University and the University of
Utah. Sera Prognostics is led by the former President of Myriad Genetics, who during his tenure,
built Myriad’s revenues from $2 million to over $300 million. We invested in a heavily
oversubscribed Series A round alongside InterWest Partners, Domain Associates and Catalyst
Health Ventures.
• Cleave Biosciences is a Caltech spinoff that is developing novel oncology therapies by targeting
protein degradation pathways. The scientific founder is one of the world’s foremost experts on
protein degradation, and his last company was acquired in 2009 by Onyx Pharmaceuticals. Osage
2. invested in a tranched Series A financing round alongside US Venture Partners, 5AM, OrbiMed,
Clarus Ventures and Astellas Ventures.
Company Tracking
We continue to actively track the progress of your start-ups in order to identify potential financing
opportunities, and our internal database has grown accordingly over the past six months. We are now
actively following 1,088 start-ups, which we define as any company that has received third-party funding
or is likely to receive funding over the next 12 months (this number includes early, nascent technologies
as well).
Using these data, below is a sector distribution of the companies we are tracking in the Osage database.
The chart on the left shows the overall sector distribution of the companies in our database, while the
chart on the right shows a breakdown of bioscience companies into industry subsectors. Currently, 51%
of the Fund’s capital is invested in life science companies and 49% in physical science companies.
Sector
D
istribution
Bio
Subsectors
Osage Blog
We encourage you to continue reading and contributing to our blog at www.blogoup.com. The blog
provides commentary on investment and technology trends that are of interest to members of the
university innovation community. You might find several recent posts to be of interest, including
Pharma-Academic collaborations, a feature on rare diseases, and the academic drug discovery landscape.
2 Osage University Partners
3. Team
Recently, we have been focusing intensively on building out our team in order to provide deeper support
in the life sciences. In January, we will announce the hiring of a new Partner at Osage who will
spearhead our life science efforts. We think you will be pleased with the quality of our new partner on
many dimensions, including the quality of his investment experience, scientific pedigree and reputation in
the venture industry. We look forward to introducing you to our new Partner in early 2012.
We also strongly encourage communication, so please feel free to contact any of us with additional
company opportunities, questions, or suggestions.
Thank you for your continued support, and we wish you, and your offices, all the best in 2012.
Portfolio Companies
Company Description University Co-investors
Developing new molecular imaging agents Alta Partners, Eli Lilly
capable of identifying Alzheimer’s Disease Penn Ventures, Pfizer Ventures,
at its earliest stages Safeguard Scientifics
Cleave Biosciences is developing novel
5AM, USVP, OrbiMed, Clarus
therapeutics targeting the Ubiquitin- Caltech
Ventures, Astellas Ventures
Proteosome System (UPS)
A global digital clinical research organization Morgan Stanley Venture
U of Florida
(dCRO) Partners, Hatteras Ventures
Biopharmaceutical company dedicated to Quaker BioVentures, Domain
developing and commercializing novel Penn Associates, MedImmune
therapeutic Arginase inhibitors Ventures, NewSpring Capital
Developing and commercializing advanced Burrill & Company, Khosla
bio-fuels, the new generation of bio-based Caltech Ventures, Total Energy Fund,
fuels and chemicals Virgin Green Fund
The Column Group, Alta
Novel vaccine technologies for infectious and
Caltech Partners, Versant Ventures,
malignant diseases
ProQuest
Developing the next generation of receptor
Celtic Pharma, HBM
tyrosine kinase inhibitors for the treatment of Yale
BioCapital, Purdue Pharma
cancer
Unique technology platform to manufacture a
August Capital, Lux Capital,
new breed of monolithic opto-electronic Caltech
NEA, Sevin Rosen Funds
devices in a low cost CMOS process
Developing electronic circuits that can stretch Penn
up to 400% North Bridge Ventures
U of Illinois
Proprietary biomarkers that are predictive of BYU Domain Associates, InterWest,
preterm birth U of Utah Catalyst Ventures
Osage University Partners 3
4. DC to AC energy conversion devices for the Battery Ventures, Rho
U of Illinois
solar industry Ventures
NovaCath™ IV delivery system Michigan Arboretum Ventures, Flagship
Biogen IDEC, Clarus
Developing safer and more effective drugs for Ventures, MedImmune
Rockefeller
autoimmune and inflammatory diseases Ventures, Thomas McNerney
& Partners, Venrock
4 Osage University Partners