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Welcome
Prevalence of obsessive-compulsive disorder (OCD)
among Iraqi undergraduate medical students in time of
COVID-19 pandemic
Dr. Imdadul Magfur
MD(Phase-B) resident
Psychiatry
Sylhet M.A.G Osmani Medical College
Authors
 Taqi Mohammed
 Shaymaa Abdul Lateef
 Ali A. Abutiheen
 Hasanain Faisal Ghazi
 Naeem Shami Abood
doi.org/10.1186/s430
45-021-00086-9
● Received: 18 December,2020
● Accepted: 18 January,2021
● Published online: 08 February,2021
● Published on: Middle East Current
Psychiatry
● Publisher:SpringerLink.
(https://www.springer.com/in)
Journal Information
Source
Abbreviations
 OCD: Obsessive-compulsive disorder;
 OCI-R: Obsessive-Compulsive Inventory Revised scale
 COVID-19: Coronavirus disease
Background
• Obsessive-compulsive disorder (OCD) is reported to be the fourth most
frequent mental disorder worldwide (Asghar MA, et al., 2020).
• It causes unwanted thoughts (obsessions) and repetitive actions
(compulsions)
• OCD lifetime prevalence is estimated to be 2.3% ranging from 1.1-3.3%
(APA,2017).
(Contd.)
• Patients with OCD can have one or more groups OCD symptoms. These
symptoms can include an obsession with contamination and washing
rituals, frequent checking, persistent nasty or religious thoughts,
uniformity and ordering, and others (Raynal P, et al., 2019).
• Patients with OCD might be with other co-existing mental hazards such
as anxiety disorder, post-traumatic stress disorder, depression,
substance use, eating disorder, and suicidal thoughts (Fenske JN, et al.,
2015; Assareh M,et al.,2016).
(Contd.)
● Onset of OCD develops mainly during adolescence and late teens
with a median age of onset of 19-20 years. That makes high school
and university students a remarkable target for screening for OCD
and OCD symptoms. (2)
● Studies reported double rates of OCD among university students in
comparison to general population.(15)
(Contd.)
● This age group is more prone to other mental hazards including
substance use and suicidal attempts that are explained to be
associated comorbidities for OCD [ 16].
● Undergraduate Medical students are at an increased risk for OCD, due
to the stressful nature of medical schools as part of the heavy
curriculum & less leisure time.(4)
(Contd.)
● Moreover, medical students are taught, trained and asked to be
more precise, perfect, and obsessive a little bit more.(12)
● On the other hand, OCD can adversely affect academic
performance, general well-being, social interaction, and suicidal
thoughts. Issues that might have a huge impact on life unless
being diagnosed early and properly managed [17].
• COVID-19 pandemic is expected to have a negative effect on OCD
patients and medical students as a general stressor on health and
communities ;by closure of medical schools and the shifting toward
online learning, and by the increasing efforts of handwashing and
general hygiene as an essential step in COVID-19 prevention which
might trigger the obsession with contamination and compulsive
washing of hands. [18, 19, 20].
(Contd.)
Objective of Study
● Estimate the prevalence of the suggestive symptom of OCD among
a sample of medical students in Iraqi medical colleges during the
COVID-19 pandemic era and to assess the associated psychological
symptoms.
● association of the probability of being OCD with the related
sociodemographic features and other psycho-logical symptoms.
Methods
Study design
Analytic cross-sectional study
Sampling method
convenient sampling
August 2020 to October 2020
Study period
Study place and participants
 the study included all medical students attending different Iraqi
medical colleges except Kurdistan (north of Iraq)
 The total sample size was 1644
Data collection tools
 Structured questionnaire containing sociodemographic features and
associated risk factors
 Obsessive-Compulsive Inventory-Revised scale (OCI-R)
Data collection procedure
 Data were collected by a structured questionnaire submitted online
through different groups for medical students including Facebook,
telegram, and WhatsApp groups for 2 weeks period.
 OCI-R was applied to all the students and out of 72, score more
than 27 was considered as probable OCD.
Statistical analysis
 Descriptive statistics examined mean and standard deviation (SD) for
numerical data while categorical data were presented by frequency table.
 Association between categorical variables was performed by the chi square
test and the difference between means was performed by an independent
sample t test
 A value of less than 0.05 was considered statistically significant.
 Data were analyzed using SPSS version 23.
Ethics
 The study was approved by the ethical review committee of
the Medical Research Bioethical Committee
 Informed written consents were taken from all participants.
Results
● The results showed that, According to the results mentioned in
Table 1, more than two-thirds (67.9%) of the participants were
females, only 3.5% were married, around one-third (32.3%) are
from the first stage.
● Less than one quarter (21.5%) mentioned that they have a family
member suffering from OCD.
Table 1: Frequency distribution of Socio-demographic features of study participants (n= 1644)
Categorial Variables Frequency Percentage
Gender
Male 528 32.1
Female 1116 67.9
Marital status
Single 1586 96.5
Married 58 3.5
College stages
First stage 531 32.3
Second stage 327 19.9
Third stage 336 20.4
Fourth stage 199 12.1
Fifth stage 133 8.1
Sixth stage 118 7.2
Categorical Variables Frequency Percentage
Place of living
Baghdad 186 11.3
Wasit 285 17.3
Karbala 333 20.3
Thi-qar 111 6.8
Nineveh 2 0.1
Qadisiyyah 60 3.6
Babil 82 5.0
Najaf 425 25.9
Muthanna 19 1.2
Basra 103 6.3
Kirkuk 1 0.1
Family history of OCD
No 1291 78.5
Yes 353 21.5
(Contd.)
Continuous Variables Mean Standard deviation
Age of participants (years)
20.73 1.83
Number of sleep hours
8.11 1.85
Table 2: Frequency distribution of other psychological symptoms
among the study sample
Associated psychological symptoms Responses (N) Percent(%)
Worry 674 25.9
Depression 465 17.9
Drug abuse 2 0.1
Sleeping disorders 476 18.3
Feeding disorders 283 10.9
Stress 617 23.7
Other 84 3.2
Total 2601 100
Figure 1: Frequency distribution of OCD categories among participant students (n-1644)
(Contd.)
 Regarding the items that represented obsessing symptoms, ”extremely or a
lot of was:
 upset by unpleasant thoughts that come into mind against will (51.8%)
 frequently get nasty thoughts & have difficulty in getting rid of them (42%)
 upset if objects are not arranged properly (40.9%)
 Check things more often than necessary (29.6%)
 Suffered from hoarding symptoms related to OCD (28%)
 had to wash or clean themselves simply because they feel they were
contaminated (19.4%)
Discussion
 This is one of the scarce worldwide studies conducted for assessment of
OCD and investigation of associated psychological symptoms and socio-
demographic features.
 Prevalence of probable OCD in this sample is 43% which is higher than
studies from other countries ranging from 3.8 to 35.8% in pre pandemic
period but in congruence with an online Canadian survey conducted
during CoVID-19 pandemic.
 Correlation of OCD with stress, anxiety and depressive symptoms was
reported by similar studies (4)
(Contd.)
 People with OCD often have other psychological comorbidities such as
depressive or bipolar disorder or an anxiety disorder (76%) (29)
 COVID-19 most probably acted as a stressor leading to higher
prevalence of OCD as well as other psychological symptoms in addition
to that medical students have relatively higher mental health problems
than the general population(31)
(Contd.)
 Statistically ,there is a highly significant association between OCD and
college years which aligns with the previous study conducted among
Brazilian medical students(4)
 Statistical analysis showed that there was no significant gender
difference according to the presence of OCD which is consistent with
the findings of other researchers(4,9)
(Contd.)
● A non-significant association was found between family history and
OCD frequency. This is in contrast to the finding of other authors [9,
23] who stated that a family history of OCD was more reported from
students with OCD than from normal ones. This finding could be
explained by the presence of additional environmental stressors
which may have triggered recent OCD cases rather than genetic
factors.
Strengths and Limitations
Limitations:
 The diagnosis of OCD was not
confirmed by clinical interview
 No causal association can be
ascertained
 Convenient sampling method
may limit generalization of
results
 The pandemic cannot be
confirmed as the exact cause of
OCD, so that Longitudinal
researches are necessary
Strengths:
 Included a large sample size
from different Iraqi cities
 Well-validated instrument had
been used.
 Prevalence of OCD and its
associated factors was
evaluated for the first time
during the COVID-19 outbreak
among medical students
Conclusion
● High prevalence of OCD and other psychological symptoms among
medical students during COVID-19 outbreak.
● Symptoms of OCD often hidden, negatively influence many life aspect of
these students
● Efforts should be made by corresponding college authorities to early
identify & treat this condition
● Further studies are needed to both establish a causal relationship and
identify other psychological impact of the pandemic on both students
and the general population
Reference
● American PsychiatricAssociation, Obsessive-Compulsive Disorder (OCD), last
updated July 2017.Accessed at 22-10-2020.Available at: https://www.
psychiatry.org/patients-families/ocd/what-is-obsessive-compulsive-disorder
● Fenske JN, Petersen K (2015) Obsessive-compulsive disorder: diagnosis and
management.American family physician. 92(10):896–903
● Asghar MA, RehmanAA, ShafiqY, SiddiqA, Zehravi M, Khan K,Asghar MA,Abedin S
(2020) Relationship of obsessive-compulsive disorders with religion and psychosocial
attitude among local medical college students of Karachi: an epidemiological study.
JPMA 70:1563
● Raynal P, MelioliT, Chabrol H (2019) Personality disorder traits in young adults with
subclinical obsessive-compulsive symptoms: not just traits related to obsessive-
compulsive personality. Bulletin of the Menninger Clinic. 83(4):433–452
● JaisooryaTS, ReddyYJ, Nair BS, RaniA, Menon PG, Revamma M, JeevanCR, Radhakrishnan
KS, JoseV,Thennarasu K (2017) Prevalence and correlates of obsessive-compulsive disorder
and subthreshold obsessive compulsive disorder among college students in Kerala, India.
Indian J Psychiatr. 59(1):56
● Assareh M, RakhshaniT, Kashfi M,Ayazi M (2016) Status of obsessive compulsive disorder
among Iranian college students in Kermanshah, Iran. J Hum Environ Health Promot.
1(4):213–219
● Huz I, Nyer M, Dickson C, FarabaughA,Alpert J, Fava M, Baer L (2016) Obsessive-
compulsive symptoms as a risk factor for suicidality in US college students. J Adolesc
Health. 58(4):481–484
● Sulkowski ML, MariaskinA, Storch EA (2011) Obsessive-compulsive spectrum disorder
symptoms in college students. Journal ofAmerican College Health. 59(5):342–348
● Lei X, Chen C, He Q, Chen C, Moyzis RK, Xue G, Chen X, Cao Z, Li J, Li H, Zhu B (2012)
Sex determines which section of the SLC6A4 gene is linked to obsessive–compulsive
symptoms in normal Chinese college students. J Psychiatric Res. 46(9):1153–1160
● El-GilanyAH,Amro M, Eladawi N, Khalil M (2019) Mental health status of medical students:
a single faculty study in Egypt. J Nervous Ment Dis.207(5):348–354
● Fineberg NA,VanAmeringen M, Drummond L, Hollander E, Stein DJ, Geller D et al (2020)
How to manage obsessive-compulsive disorder (OCD) under COVID-19: a clinician’s guide
from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) and
the Obsessive-Compulsive Research Network (OCRN) of the European College of
Neuropsychopharmacology. Compr Psychiatry. 100:152174
● TanirY, Karayagmurlu A, Kaya İ, KaynarTB,Türkmen G, Dambasan BN, MeralY, Coşkun M
(2020) Exacerbation of obsessive compulsive disorder symptoms in children and adolescents
during COVID-19 pandemic.Psychiatry Research. 293:113363
● ChakrabortyA, Karmakar S (2020) Impact of COVID-19 on obsessive compulsive disorder
(OCD). Iranian Journal of Psychiatry. 15(3):256–259
● ZengW, Chen R,Wang X, Zhang Q, DengW (2019) Prevalence of mental health problems
among medical students in China. Medicine 98(18):e15337
ThankYou
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Prevalence of OCD among Iraqi medical students during COVID-19

  • 2. Prevalence of obsessive-compulsive disorder (OCD) among Iraqi undergraduate medical students in time of COVID-19 pandemic
  • 3. Dr. Imdadul Magfur MD(Phase-B) resident Psychiatry Sylhet M.A.G Osmani Medical College
  • 4. Authors  Taqi Mohammed  Shaymaa Abdul Lateef  Ali A. Abutiheen  Hasanain Faisal Ghazi  Naeem Shami Abood
  • 5. doi.org/10.1186/s430 45-021-00086-9 ● Received: 18 December,2020 ● Accepted: 18 January,2021 ● Published online: 08 February,2021 ● Published on: Middle East Current Psychiatry ● Publisher:SpringerLink. (https://www.springer.com/in) Journal Information Source
  • 6. Abbreviations  OCD: Obsessive-compulsive disorder;  OCI-R: Obsessive-Compulsive Inventory Revised scale  COVID-19: Coronavirus disease
  • 8. • Obsessive-compulsive disorder (OCD) is reported to be the fourth most frequent mental disorder worldwide (Asghar MA, et al., 2020). • It causes unwanted thoughts (obsessions) and repetitive actions (compulsions) • OCD lifetime prevalence is estimated to be 2.3% ranging from 1.1-3.3% (APA,2017).
  • 9. (Contd.) • Patients with OCD can have one or more groups OCD symptoms. These symptoms can include an obsession with contamination and washing rituals, frequent checking, persistent nasty or religious thoughts, uniformity and ordering, and others (Raynal P, et al., 2019). • Patients with OCD might be with other co-existing mental hazards such as anxiety disorder, post-traumatic stress disorder, depression, substance use, eating disorder, and suicidal thoughts (Fenske JN, et al., 2015; Assareh M,et al.,2016).
  • 10. (Contd.) ● Onset of OCD develops mainly during adolescence and late teens with a median age of onset of 19-20 years. That makes high school and university students a remarkable target for screening for OCD and OCD symptoms. (2) ● Studies reported double rates of OCD among university students in comparison to general population.(15)
  • 11. (Contd.) ● This age group is more prone to other mental hazards including substance use and suicidal attempts that are explained to be associated comorbidities for OCD [ 16]. ● Undergraduate Medical students are at an increased risk for OCD, due to the stressful nature of medical schools as part of the heavy curriculum & less leisure time.(4)
  • 12. (Contd.) ● Moreover, medical students are taught, trained and asked to be more precise, perfect, and obsessive a little bit more.(12) ● On the other hand, OCD can adversely affect academic performance, general well-being, social interaction, and suicidal thoughts. Issues that might have a huge impact on life unless being diagnosed early and properly managed [17].
  • 13. • COVID-19 pandemic is expected to have a negative effect on OCD patients and medical students as a general stressor on health and communities ;by closure of medical schools and the shifting toward online learning, and by the increasing efforts of handwashing and general hygiene as an essential step in COVID-19 prevention which might trigger the obsession with contamination and compulsive washing of hands. [18, 19, 20]. (Contd.)
  • 14. Objective of Study ● Estimate the prevalence of the suggestive symptom of OCD among a sample of medical students in Iraqi medical colleges during the COVID-19 pandemic era and to assess the associated psychological symptoms. ● association of the probability of being OCD with the related sociodemographic features and other psycho-logical symptoms.
  • 16. Study design Analytic cross-sectional study Sampling method convenient sampling August 2020 to October 2020 Study period
  • 17. Study place and participants  the study included all medical students attending different Iraqi medical colleges except Kurdistan (north of Iraq)  The total sample size was 1644
  • 18. Data collection tools  Structured questionnaire containing sociodemographic features and associated risk factors  Obsessive-Compulsive Inventory-Revised scale (OCI-R)
  • 19. Data collection procedure  Data were collected by a structured questionnaire submitted online through different groups for medical students including Facebook, telegram, and WhatsApp groups for 2 weeks period.  OCI-R was applied to all the students and out of 72, score more than 27 was considered as probable OCD.
  • 20. Statistical analysis  Descriptive statistics examined mean and standard deviation (SD) for numerical data while categorical data were presented by frequency table.  Association between categorical variables was performed by the chi square test and the difference between means was performed by an independent sample t test  A value of less than 0.05 was considered statistically significant.  Data were analyzed using SPSS version 23.
  • 21. Ethics  The study was approved by the ethical review committee of the Medical Research Bioethical Committee  Informed written consents were taken from all participants.
  • 23. ● The results showed that, According to the results mentioned in Table 1, more than two-thirds (67.9%) of the participants were females, only 3.5% were married, around one-third (32.3%) are from the first stage. ● Less than one quarter (21.5%) mentioned that they have a family member suffering from OCD.
  • 24. Table 1: Frequency distribution of Socio-demographic features of study participants (n= 1644) Categorial Variables Frequency Percentage Gender Male 528 32.1 Female 1116 67.9 Marital status Single 1586 96.5 Married 58 3.5 College stages First stage 531 32.3 Second stage 327 19.9 Third stage 336 20.4 Fourth stage 199 12.1 Fifth stage 133 8.1 Sixth stage 118 7.2
  • 25. Categorical Variables Frequency Percentage Place of living Baghdad 186 11.3 Wasit 285 17.3 Karbala 333 20.3 Thi-qar 111 6.8 Nineveh 2 0.1 Qadisiyyah 60 3.6 Babil 82 5.0 Najaf 425 25.9 Muthanna 19 1.2 Basra 103 6.3 Kirkuk 1 0.1 Family history of OCD No 1291 78.5 Yes 353 21.5
  • 26. (Contd.) Continuous Variables Mean Standard deviation Age of participants (years) 20.73 1.83 Number of sleep hours 8.11 1.85
  • 27. Table 2: Frequency distribution of other psychological symptoms among the study sample Associated psychological symptoms Responses (N) Percent(%) Worry 674 25.9 Depression 465 17.9 Drug abuse 2 0.1 Sleeping disorders 476 18.3 Feeding disorders 283 10.9 Stress 617 23.7 Other 84 3.2 Total 2601 100
  • 28. Figure 1: Frequency distribution of OCD categories among participant students (n-1644)
  • 29. (Contd.)  Regarding the items that represented obsessing symptoms, ”extremely or a lot of was:  upset by unpleasant thoughts that come into mind against will (51.8%)  frequently get nasty thoughts & have difficulty in getting rid of them (42%)  upset if objects are not arranged properly (40.9%)  Check things more often than necessary (29.6%)  Suffered from hoarding symptoms related to OCD (28%)  had to wash or clean themselves simply because they feel they were contaminated (19.4%)
  • 30.
  • 31.
  • 33.  This is one of the scarce worldwide studies conducted for assessment of OCD and investigation of associated psychological symptoms and socio- demographic features.  Prevalence of probable OCD in this sample is 43% which is higher than studies from other countries ranging from 3.8 to 35.8% in pre pandemic period but in congruence with an online Canadian survey conducted during CoVID-19 pandemic.  Correlation of OCD with stress, anxiety and depressive symptoms was reported by similar studies (4)
  • 34. (Contd.)  People with OCD often have other psychological comorbidities such as depressive or bipolar disorder or an anxiety disorder (76%) (29)  COVID-19 most probably acted as a stressor leading to higher prevalence of OCD as well as other psychological symptoms in addition to that medical students have relatively higher mental health problems than the general population(31)
  • 35. (Contd.)  Statistically ,there is a highly significant association between OCD and college years which aligns with the previous study conducted among Brazilian medical students(4)  Statistical analysis showed that there was no significant gender difference according to the presence of OCD which is consistent with the findings of other researchers(4,9)
  • 36. (Contd.) ● A non-significant association was found between family history and OCD frequency. This is in contrast to the finding of other authors [9, 23] who stated that a family history of OCD was more reported from students with OCD than from normal ones. This finding could be explained by the presence of additional environmental stressors which may have triggered recent OCD cases rather than genetic factors.
  • 38. Limitations:  The diagnosis of OCD was not confirmed by clinical interview  No causal association can be ascertained  Convenient sampling method may limit generalization of results  The pandemic cannot be confirmed as the exact cause of OCD, so that Longitudinal researches are necessary Strengths:  Included a large sample size from different Iraqi cities  Well-validated instrument had been used.  Prevalence of OCD and its associated factors was evaluated for the first time during the COVID-19 outbreak among medical students
  • 40. ● High prevalence of OCD and other psychological symptoms among medical students during COVID-19 outbreak. ● Symptoms of OCD often hidden, negatively influence many life aspect of these students ● Efforts should be made by corresponding college authorities to early identify & treat this condition ● Further studies are needed to both establish a causal relationship and identify other psychological impact of the pandemic on both students and the general population
  • 41. Reference ● American PsychiatricAssociation, Obsessive-Compulsive Disorder (OCD), last updated July 2017.Accessed at 22-10-2020.Available at: https://www. psychiatry.org/patients-families/ocd/what-is-obsessive-compulsive-disorder ● Fenske JN, Petersen K (2015) Obsessive-compulsive disorder: diagnosis and management.American family physician. 92(10):896–903 ● Asghar MA, RehmanAA, ShafiqY, SiddiqA, Zehravi M, Khan K,Asghar MA,Abedin S (2020) Relationship of obsessive-compulsive disorders with religion and psychosocial attitude among local medical college students of Karachi: an epidemiological study. JPMA 70:1563 ● Raynal P, MelioliT, Chabrol H (2019) Personality disorder traits in young adults with subclinical obsessive-compulsive symptoms: not just traits related to obsessive- compulsive personality. Bulletin of the Menninger Clinic. 83(4):433–452
  • 42. ● JaisooryaTS, ReddyYJ, Nair BS, RaniA, Menon PG, Revamma M, JeevanCR, Radhakrishnan KS, JoseV,Thennarasu K (2017) Prevalence and correlates of obsessive-compulsive disorder and subthreshold obsessive compulsive disorder among college students in Kerala, India. Indian J Psychiatr. 59(1):56 ● Assareh M, RakhshaniT, Kashfi M,Ayazi M (2016) Status of obsessive compulsive disorder among Iranian college students in Kermanshah, Iran. J Hum Environ Health Promot. 1(4):213–219 ● Huz I, Nyer M, Dickson C, FarabaughA,Alpert J, Fava M, Baer L (2016) Obsessive- compulsive symptoms as a risk factor for suicidality in US college students. J Adolesc Health. 58(4):481–484 ● Sulkowski ML, MariaskinA, Storch EA (2011) Obsessive-compulsive spectrum disorder symptoms in college students. Journal ofAmerican College Health. 59(5):342–348 ● Lei X, Chen C, He Q, Chen C, Moyzis RK, Xue G, Chen X, Cao Z, Li J, Li H, Zhu B (2012) Sex determines which section of the SLC6A4 gene is linked to obsessive–compulsive symptoms in normal Chinese college students. J Psychiatric Res. 46(9):1153–1160
  • 43. ● El-GilanyAH,Amro M, Eladawi N, Khalil M (2019) Mental health status of medical students: a single faculty study in Egypt. J Nervous Ment Dis.207(5):348–354 ● Fineberg NA,VanAmeringen M, Drummond L, Hollander E, Stein DJ, Geller D et al (2020) How to manage obsessive-compulsive disorder (OCD) under COVID-19: a clinician’s guide from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) and the Obsessive-Compulsive Research Network (OCRN) of the European College of Neuropsychopharmacology. Compr Psychiatry. 100:152174 ● TanirY, Karayagmurlu A, Kaya İ, KaynarTB,Türkmen G, Dambasan BN, MeralY, Coşkun M (2020) Exacerbation of obsessive compulsive disorder symptoms in children and adolescents during COVID-19 pandemic.Psychiatry Research. 293:113363 ● ChakrabortyA, Karmakar S (2020) Impact of COVID-19 on obsessive compulsive disorder (OCD). Iranian Journal of Psychiatry. 15(3):256–259 ● ZengW, Chen R,Wang X, Zhang Q, DengW (2019) Prevalence of mental health problems among medical students in China. Medicine 98(18):e15337