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GROUP FINANCIAL STATEMENT FOR 2007




January 25, 2008




2007 was a really good year for Novozymes. Growth was the theme of the year, with sales
growth higher than expected at 14%. The financial results were satisfactory, particularly in
the light of high energy and raw material prices. Unfavorable exchange rate movements had
a negative impact on the results measured in DKK. Growth in earnings was 11%, and free
cash flow was DKK 963 million. The high rate of sales growth is expected to continue in
2008 and onwards, and therefore it has been decided to expand the production in the USA.
            •    Novozymes’ sales rose by 14% in local currencies in 2007. Measured in DKK sales rose
                 by 9% to DKK 7,438 million from DKK 6,802 million in 2006. Growth excluding
                 acquisitions was 12%
            •    Operating profit rose by 11% to DKK 1,481 million in 2007 from DKK 1,340 million in
                 2006. One-off items (cf. Stock exchange announcement no. 14/2007) had a positive
                 impact of approximately DKK 75 million. Operating profit excluding one-off items rose
                 by 5%. The operating profit margin including one-off items was 19.9% against 19.7%
                 in 2006
            •    Net financial costs were DKK 96 million against DKK 122 million in 2006
            •    Net profit for the period rose by 14% to DKK 1,042 million in 2007 against DKK 911
                 million in 2006. Growth excluding one-off items was 8%
            •    Earnings per share (diluted) for 2007 were DKK 16.47, an increase of 17%
            •    Free cash flow before acquisitions was DKK 963 million against DKK 1,058 million in
                 2006
            •    Return on invested capital (ROIC) rose to 21.7% from 20.2% in 2006

Outlook for 2008
Assuming that exchange rates for the company’s key currencies remain at the spot rates on January
23, 2008, expected outlook for 2008 is as follows (excluding one-off items in 2007):

            •    Growth in sales of 11–14% in local currencies and 8–11% in DKK
            •    Growth in operating profit of 2–5%
            •    Growth in net profit of 4–7%
            •    Investment before acquisitions of DKK 800-950 million
            •    Free cash flow before acquisitions of DKK 750–900 million

The Board of Directors will recommend a dividend for 2007 of DKK 5.00 per share at the Annual
Meeting of Shareholders on March 5, 2008.

Stock exchange announcement no. 1, 2008                                                       Side 1 af 27
Novozymes A/S                  Krogshøjvej 36           Telephone:                 Internet:
Investor Relations             2880 Bagsværd            +45 4446 0000              www.novozymes.com
2008-01809-01                  Denmark                  Fax:                       CVR number:
                                                        +45 4446 1002              10 00 71 27
“2007 was a really good year for Novozymes,” says Steen Riisgaard, President and CEO. “Sales growth
has never been higher. We had success almost everywhere, so growth was higher than expected. The
financial results met expectations despite rising raw material and energy prices and the declining US
dollar, so we are extremely pleased.” And he continues: “We expect growth to remain high in 2008
and this means – together with the strong political support for bioethanol production in the USA – that
we are increasing our expectation for long-term growth. Given this outlook, we will build more
capacity in the USA, simply to keep up with the growth.”

Long-term expectations
Novozymes increases its outlook for long-term organic growth from 8–9% to 8-10%. This reflects our
expectations of higher growth rates the coming years, but also a greater uncertainty in future
estimates. Underlying growth expectations for some industries have changed, especially upwards
adjustments for technical and detergent enzymes.

On this background, among other, it has been decided to build a new enzyme plant in the USA. A total
investment of DKK 300-500 million in 2009-2010 is expected.



Income statement and balance sheet
Appendices 1 & 2               Sales
                               Sales rose by 14% in local currencies in 2007. Measured in DKK sales were
14% growth in
                               DKK 7,438 million against DKK 6,802 million in 2006, an increase of 9%.
sales, of which two
                               Exchange rate movements for the company’s key currencies had a negative
percentage points
                               impact on sales in DKK of five percentage points.
from acquisitions
                               Acquired activities impacted sales positively. Excluding acquisitions, organic
                               growth in sales in local currencies was 12% in 2007.


                                      Sales in DKK million
                                                                               Distribution of sales



                                                                               3%
                                                                             4%
                                                                       10%                         Detergent enzymes
                                                                                          30%
                                                 7,438                                             Technical enzymes
                                       6,802
                                                                                                   Food enzymes
                                                                     23%                           Feed enzymes
                                                                                                   Microorganisms
                                                                                    30%            BPI


                                        2006     2007


                               Seen in isolation, sales in the fourth quarter of 2007 rose by 9% in local
                               currencies and 5% in DKK compared with 2006. Average exchange rates for
                               the company’s key currencies were lower in the fourth quarter of 2007 than
                               in the same period of 2006.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                        Page 2 of 27

Group financial statement for 2007
Sales in i DKK million




                                                                     2,263
                                                 2,239
                                       2,040




                                                          1,977




                                                                                         1,699
                                                                             1,603




                                                                                                              705
                                                                                                    700




                                                                                                                                      134
                                                                                                                     348


                                                                                                                               308




                                                                                                                                                  224
                                     Detergent enzymes   Technical enzymes   Food enzymes           Feed enzymes    M icroorganisms         BPI


                                                                                          2006    2007




Sales of enzymes               Enzymes
rose by 14%; the               Growth in local currencies was 14% in 2007, while sales of enzymes in DKK
weak US dollar                 rose by 9% to DKK 6,906 million from DKK 6,320 million in 2006. Exchange
reduced growth in              rate movements had a negative effect on sales in DKK.
DKK                            Sales of enzymes in the fourth quarter of 2007 rose by 15% in local
                               currencies and 9% in DKK compared with the same period of 2006. Sales
                               generated by the activities acquired from Biocon Limited were approximately
                               DKK 20 million in the quarter.

12% growth in sales            Sales of detergent enzymes rose by 12% in local currencies and 10% in DKK
of detergent                   compared with 2006. Throughout the year the high level of growth was
enzymes                        driven first and foremost by rising demand and an increased market share in
                               Europe. However, developments on the American and Asian markets also
                               contributed to the positive trend in 2007 compared with previous years.
                               Sales of detergent enzymes in the fourth quarter rose by 9% in local
                               currencies and 7% in DKK.

Over 40% growth in             Sales of technical enzymes rose by 22% in local currencies and 14% in DKK
enzymes for                    in 2007. Growth in DKK was particularly affected by the negative trend in the
bioethanol                     US dollar. There was good growth in all industries other than the textile
                               industry.
                               Sales of enzymes for bioethanol rose by more than 40% in 2007 to DKK 1
                               billion, equivalent to approximately 13% of Novozymes’ total sales. The year’s




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                                                     Page 3 of 27

Group financial statement for 2007
growth was driven by the increase in bioethanol production in the USA and
                               strengthening of Novozymes’ market position. There was an increase in sales
                               to textile mills, but lower sales to the denim segment as a result of a change
                               in fashion trends. Total sales to the textile industry ended 2% lower in local
                               currencies than in 2006.
                               Taking the fourth quarter of 2007 in isolation, sales of technical enzymes rose
                               by 19% in local currencies and 10% in DKK compared with the same period
                               of 2006. This trend was primarily due to increased sales of enzymes for
                               bioethanol production.

9% growth in sales             Sales of food enzymes rose by 9% in local currencies and 6% in DKK in
of food enzymes                2007. This growth can mainly be attributed to increased penetration of fresh-
                               keeping enzymes in the baking industry in Europe. There was also increased
                               use of enzymes in the brewing industry, as a result of rising ingredient prices
                               coupled with a decline in quality.
Positive effect from           Sales in the fourth quarter rose by 19% in local currencies and 14% in DKK
activities acquired in         compared with the same period in 2006. The trend for the quarter was
India                          positively affected by the acquired activities from Biocon Limited, as well as
                               comparison with a weak quarter in 2006.

Growth in sales of             Sales of feed enzymes rose by 5% in local currencies and 1% in DKK in 2007.
feed enzymes                   Sales were negatively affected by lower exchange rates. There was growth in
despite lower prices           sales of enzymes for plant proteins but total growth was reduced by low
in the market                  volume growth and lower prices for phytase products.
                               Seeing the fourth quarter of 2007 in isolation, sales in local currencies rose by
                               11% and 6% in DKK. Ronozyme® NP, which was recently launched in the
                               American and Asian markets, had a positive impact on the quarter’s results.
                               There was also a small positive effect from the acquisition of Biocon Limited’s
                               enzyme activities.

                               Microorganisms
Low sales within               Sales of microorganisms in 2007 were a disappointing 5% lower in local
institutional and              currencies than in 2006. Measured in DKK sales were 11% lower as a result
household cleaning             of the unfavorable trend in the US dollar. This business area accounts for a
                               high proportion of sales on the US market.

                               2007 saw the discontinuation of an unprofitable product line, which, as
                               expected, has had a negative effect on sales growth as well as reducing
                               Novozymes’ market share. Growth in sales of microorganisms for wastewater
                               treatment and plant care was unable to counteract the effect of lower sales
                               than expected within institutional and household cleaning. The purchase of
                               the Canadian company Philom Bios Inc. was completed in December 2007.
                               Sales from this acquisition will not impact sales of microorganisms until 2008.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                               Page 4 of 27

Group financial statement for 2007
Biopharmaceutical ingredients (BPI)
Expected growth in             Sales of biopharmaceutical ingredients in 2007 rose to DKK 224 million
BPI                            compared with DKK 134 million in 2006, an increase of 67%. Measured in
                               local currencies the increase was 64%. Acquisitions in 2006 had a positive
                               impact of approximately DKK 118 million on sales for the year.
                               Taking the fourth quarter of 2007 in isolation, sales of biopharmaceutical
                               ingredients were DKK 23 million against DKK 75 million in the same period of
                               2006. This development is due partly to an anticipated decline in contract
                               volumes, together with a change in the quarterly sales distribution during
                               2007 compared with 2006.

                               As noted previously, this industry is subject to substantial quarterly variation
                               in sales patterns, as sales are generally composed by a small number of
                               relatively large transactions.

                               Sales by geographical area



                                           5% (10%)


                                                       20%                              6% (7%)

                                     9% (10%)
                                                                                                  Europe/MEA
                                                                               41%
                                                                                                  North America
                                                  7%
                                                                                                  Latin America
                                                                                                  Asia

                                      17% (26%)
                                                          32%



                                                  Growth in DKK/(Growth in local currency)




                               Sales in Europe/MEA rose by 7% in local currencies and 6% in DKK. Growth
                               for the year was primarily driven by increased sales of enzymes for the
                               detergent and baking industries. The fourth quarter ended lower than the
                               fourth quarter of 2006 as a result of low sales within biopharmaceutical
                               ingredients and feed enzymes.

Enzymes for
                               Sales in North America in 2007 rose by 26% in local currencies and 17% in
bioethanol drive
                               DKK. This positive trend was mainly due to sales of enzymes for bioethanol
high growth in
                               production, plus the effect of the activities acquired within biopharmaceutical
North America




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                  Page 5 of 27

Group financial statement for 2007
ingredients (BPI). The fourth quarter of 2007 also saw growth in detergent
                               enzymes, while the development in sales of microorganisms and BPI reduced
                               overall growth for the quarter.

                               Sales to Latin America rose by 10% in local currencies and 9% in DKK in
                               2007. Growth for the year was driven by sales of detergent and feed
                               enzymes, as well as enzymes for the brewing industry.

Double-digit sales             Sales in Asia rose by 10% in local currencies and 5% in DKK. There was
growth in Asia                 general double-digit growth in most industries, but growth within enzymes
                               for the detergent and brewing industries, and feed enzymes was particularly
                               significant. The fourth quarter was positively affected by the enzyme activities
                               acquired in India, and high sales of the newly launched feed enzyme
                               Ronozyme® NP.

Appendix 6                     New products
10 new products                One new enzyme product was launched in the fourth quarter of 2007:
launched in 2007,
                                     •
the highest number                       Sucrozyme, an enzyme for the food industry used to manufacture
ever                                     sweeteners

                               This means that a total of 10 new products were launched in 2007, the
                               highest number ever. Around 25% of enzyme sales in 2007 related to
                               products launched in the last five years.

Appendices 1 & 4               Costs, License fees and Other operating income
                               Total costs excluding net financials and tax rose by 10% in 2007 to
                               DKK 6,080 million from DKK 5,521 million in 2006. This increase was
                               primarily related to higher sales in 2007, together with the effects of the
                               increased level of activity from acquisitions and within research.
Productivity
                               Cost of goods sold rose by 11% in 2007 compared with 2006. This trend was
improvements
                               mainly driven by increased sales within both enzymes and biopharmaceutical
reducing effect of
                               ingredients. Productivity improvements reduced the negative effects of higher
higher energy and
                               energy and raw material prices on the cost level.
raw material prices
                               The gross margin for 2007 was 53.1% against 53.7% in 2006. The main
Gross margin on a
                               reasons for the lower gross margin were a relatively low margin on the sale of
par with 2006,
                               products from activities acquired in 2006 plus lower exchange rates through
adjusted for
                               2007, particularly for the USD and JPY. The gross margin for 2007 is on a par
currency effect and
                               with 2006 when adjusted for the negative currency effect and the lower
acquisitions
                               margin on sales of products from acquired activities in 2006 – despite higher
                               raw material prices.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                              Page 6 of 27

Group financial statement for 2007
Other operating costs rose by 9% to DKK 2,591 million for 2007. This
                               increase was due primarily to rising sales and acquired activities. Costs of
                               sales, distribution and business development rose by 9%, representing 12%
                               of sales. Research and development costs rose by 13%, representing 13% of
                               sales, while there was an increase of 4% in administrative costs in 2007.

                               Other operating income was DKK 123 million in 2007 against DKK 59 million
                               in 2006. The main reason for this increase was one-off items of
                               approximately DKK 75 million in the second quarter of 2007.

                               Depreciation and amortization charges rose by 4% to DKK 490 million from
                               DKK 469 million in 2006. This increase was primarily related to acquired
                               activities.

                               Operating profit
Appendix 1
11% growth in                                                                  Operating profit margin %
operating profit –                      Operating profit in DKK million


5% adjusted for
one-off items


                                                            1,481
                                                                                              19.9
                                           1,340                               19.7




                                                                                   2006    2007
                                                 2006     2007




                               Operating profit rose to DKK 1,481 million in 2007 from DKK 1,340 million in
                               2006, an increase of 11%. This result incorporates a positive one-off effect of
                               approximately DKK 75 million. Adjusted for this, growth in operating profit
                               was 5%. Growth was reduced by lower exchange rates, particularly for the
                               USD and JPY, and a lower margin on sales from activities acquired in 2006.

                               The operating profit margin, expressed as operating profit as a percentage of
High earnings level
                               sales, was 19.9% for 2007 against 19.7% in 2006. Excluding one-off items,
when adjusted for
                               the operating profit margin was 18.9%. Taking the fourth quarter in
currency
                               isolation, the operating profit margin was reduced by more than one
                               percentage point compared with 2006 as a result of negative exchange rate
                               movements. Adjusted for the currency effect and one-off items, the
                               operating profit margin for the year as a whole was on a par with 2006.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                    Page 7 of 27

Group financial statement for 2007
Net financial items
Net foreign                    Net financial costs for 2007 fell to DKK 96 million against DKK 122 million in
exchange gain                  2006. The main reason for the lower cost level in 2007 was a net foreign
reduces net financial          exchange gain of DKK 5 million, whereas there was a net foreign exchange
costs for 2007                 loss of DKK 50 million in 2006. Net interest expenses in 2007 were higher
                               than in 2006. This can be attributed to higher interest rates and debt, plus
                               the fact that net interest expenses in 2006 were positively affected by tax-
                               related non-recurring income but negatively affected by the fact that the
                               acquisition of Biocon Limited’s enzyme activities resulted in higher interest
                               expenses in the fourth quarter of 2007. Net interest-bearing debt was
                               DKK 1,769 million in 2007 against DKK 1,455 million in 2006.

Appendix 1                     Profit before tax and net profit for the period
                               Profit before tax rose by 14% to DKK 1,385 million from DKK 1,218 million
14% growth in net
                               in 2006. Adjusted for one-off items, growth in profit before tax was 8%.
profit for the year

                               Net profit for 2007 was DKK 1,042 million against DKK 911 million in 2006,
                               an increase of 14%. Net profit for the year was positively affected by one-off
                               items and a reduction in Danish corporation tax.

Appendix 3                     Cash flow, investments and acquisitions
                               Free cash flow before acquisitions was DKK 963 million in 2007 against
Increase in free cash
                               DKK 1,058 million in 2006. The reduction in free cash flow was primarily due
flow when adjusted
                               to a higher level of investment in 2007. There was also a positive effect from
for increased level of
                               tax-related one-off items in 2006.
investment

                               Cash flow from operating activities increased in 2007 as a result of increased
                               sales, which, together with ongoing optimizations, had a positive impact on
                               inventories.

High level of                  Net investments before acquisitions rose to DKK 735 million from DKK 476
investment in 2007,            million in 2006, slightly over the level expected for 2007. Investments were
among others, as a             made in a bioethanol customer service center in the USA, completion of
result of increased            cGMP production facilities in Sweden, and new research facilities in Denmark
research efforts and           and India, among other. Growth in sales also meant pressure on production
high level of                  capacity, resulting in a slight increase in the ongoing optimization
bioethanol activity            investments, and investment in the expansion of production announced for
                               China already being initiated in the fourth quarter of 2007.

                               Novozymes completed the acquisition of Philom Bios Inc. on December 10,
                               2007.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                             Page 8 of 27

Group financial statement for 2007
Appendix 1                     Return on invested capital
                               The return on invested capital after tax (ROIC) rose to 21.7% against 20.2%
ROIC of 21.7%
                               in 2006. Adjusted for one-off items, ROIC in 2007 was 20.5%.

Appendix 5                     Balance sheet and Statement of shareholders’ equity
                               Shareholders’ equity was DKK 3,667 million at December 31, 2007, against
Equity represents
                               DKK 3,393 million at January 1, 2007. Shareholders’ equity was increased by
41% of the balance
                               net profit for the period but reduced by currency translation adjustments in
sheet total
                               respect of subsidiaries’ net assets, dividend payments, and purchase of
                               treasury shares. Shareholders’ equity represented 41.3% of the balance sheet
                               total at December 31, 2007.

                               A dividend of DKK 278 million was paid for 2006. Purchase of treasury
                               shares, reduced by exercise of stock options, decreased shareholders’ equity
                               by DKK 778 million.

                               At December 31, 2007, the holding of treasury shares was 3.2 million B
                               shares, equivalent to 4.9% of the share capital.

IAS 34                         Accounting policies
                               The financial statement for the fourth quarter of 2007 has been prepared in
                               accordance with IAS 34 and the additional Danish regulations for the
                               presentation of quarterly financial statements by listed companies. The
                               financial statement follows the same accounting policies as the Group
                               financial statement for 2006.



Outlook
                               Outlook for 2008
                               The spot rates on January 23, 2008, for the company’s key currencies were
                               lower relative to the DKK than the average rates in 2007. If rates remain at
                               their current levels for the rest of 2008, the average rates for 2008 will be
                               lower than the average rates for 2007.

                                (DKK)                                                                        US D   JPY      C NY

                                Average exchange rate 2007                                                   544    4.62    71.53
                                S pot rate J anuary 23, 2008                                                 511    4.85    70.69

                                C hange in es timated average exchange rate for 2008*                        -6%     5%      -1%
                                compared with average exchange rate in 2007

                                *E s timated average exchange rate for 2008 = s pot rate J anuary 23, 2008




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                                    Page 9 of 27

Group financial statement for 2007
Novozymes expects high sales growth in local currencies to continue in 2008,
                               at around 11-14%. High raw material and energy prices, and a lower US
                               dollar rate, present challenges to the financial results. The general level of
                               activity and investments will increase compared with 2007 as a result of
                               continued high growth and the focus on long-term growth.

                               These expectations are based on exchange rates remaining at their current
Sales
                               levels for the rest of 2008, particularly the EUR, USD, JPY, and CNY. In
                               greater detail, the outlook is as follows:

                               Growth of 11–14% in local currencies and 8–11% in DKK
New products

                               Launch of 6–8 new products in 2008
Operating profit

                               Growth of 2–5% excluding one-off items in 2007
Operating profit
margin
                               A 5% change in the exchange rate for the USD is expected to have an impact
                               on operating profit in 2008 of DKK 40–60
                               One-off items approximately DKK 75 million of the operating profit in 2007
                               Operating profit margin of around 18%
Net profit for the year

                               Growth in net profit of 4–7% excluding one-off items in 2007
Investments
                               One-off items approximately DKK 56 million of the net profit in 2007
                               Investments before acquisitions of DKK 800–950 million
Free cash flow
                               The level of investment in 2008 is thus expected to exceed the level for 2007,
                               primarily as a result of the expansion of enzyme production in China and
                               further investments in research facilities in Denmark and the USA
                               The building of a new enzyme factory in the USA is expected to have an
                               impact on the investment level in 2009-2010 of DKK 300-500 million in total.
                               In 2008 expectations of minor preparatory costs have been included


                               Free cash flow of DKK 750–900 million
ROIC

                               Return on invested capital after tax (ROIC) of around 20%
Acquisition effects

                               The following acquisition effects have been incorporated in the outlook for
                               2008:
                               Enzyme activities from Biocon Limited: impact on sales of enzymes Q1–Q3 of
                               DKK 70–80 million, impact on operating profit for 2008 of approximately
                               DKK 0 million.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                            Page 10 of 27

Group financial statement for 2007
Philom Bios Inc.: impact on sales of microorganisms Q1–Q4 of approximately
                               DKK 70 million, season in sales focused around Q2, impact on operating
                               profit for 2008 of approximately DKK 0 million.


                               Long-term expectations
                               Total sales growth of 8-10% in local currencies, all segments included.
                               Distribution per industry is specified in Appendix 10.



Long-term financial targets

                               Novozymes maintains its long-term financial targets.

“10 in 10” –                   In 2005 Novozymes launched a strategic initiative with the focus on
sales of DKK 10                accelerating top-line growth. As well as further investments in market-
billion in 2010                expanding activities and acquisitions, the initiative included a vision of sales
possible                       of DKK 10 billion in 2010 – “10 in 10” – which has been incorporated in the
                               stock option programs for the Executive Management and other employees.
Operating profit               Annual growth in operating profit of at least 10%

Operating profit               Operating profit margin of around 17%
margin
ROIC                           Annual return on invested capital after tax of at least 15%




Capital structure

                               In 2007 Novozymes purchased treasury shares worth DKK 500 million,
                               corresponding to the total approved framework for share buy-backs in 2007.

                               The capital adjustment program started in 2004 was completed, as planned,
                               at the end of 2007. A total of DKK 3.5 billion of the total approved
Share buy-back                 framework of DKK 4 billion was used for share buy-backs in the period. The
program completed              program target of reducing the equity ratio to approximately 45% was
in 2007                        achieved in 2006, and at the end of 2007 the equity ratio was 41%. No
                               further share buy-backs are planned for the current year.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                             Page 11 of 27

Group financial statement for 2007
Pay-out ratio of               At the Annual Meeting of Shareholders on March 5, 2008, the Board of
31% for 2007                   Directors will recommend payment of a dividend of DKK 5.00 per share for
                               the 2007 financial year, an increase of 11% compared with 2006. In
                               accordance with the established dividend policy of repaying approximately
                               30% of net profit for the year, the dividend rate for 2007 is 31.2% against
                               30.5% for 2006.




Events after the end of the year

Partial fulfillment of         Novozymes achieved the financial targets set for the 2007 employee stock
targets in 2007                option program, but not all the non-financial targets. The Board has
incentive programs             therefore approved a 95% allocation of the stock options for the year. The
                               same applies to partial achievement of non-financial targets in the Executive
                               Management’s incentive program for 2007. Executive Management met
                               100% of its profit target for 2007, and thereby achieved 95% allocation of
                               the maximum possible number of stock options.

Executive                      At the Annual Meeting of Shareholders on March 5, 2008, the Board of
Management’s                   Directors will submit for approval the general guidelines for the Executive
2008 incentive                 Management’s incentive program. The guidelines conform to those
program                        previously submitted and approved for the incentive program for the period
                               2007–2010. As such, and assuming the guidelines are approved, the
                               Executive Management’s stock option program will be based on two financial
                               targets and several non-financial targets, plus fulfillment of Novozymes’
                               ambition of achieving sales of DKK 10 billion in 2010. The exercise price is
                               calculated on the basis of the average closing price on the OMX Nordic
                               Exchange Copenhagen A/S on the first five trading days after publication of
                               the financial statements for 2007. The underlying number of stock options in
                               the program follows from this. The stock options have a qualifying period of
                               one year and a vesting period of three years followed by an exercise period of
                               five years. Based on the current basic salaries paid to the Executive
                               Management, the maximum total value of the program for 2008 according
                               to the Black-Scholes model will be DKK 29.9 million. The stock option
                               program will be accrued and expensed over four years, corresponding to the
                               program’s service period. The carrying amount for 2008 is approximately
                               DKK 8 million.

                               The proposed guidelines for the Executive Management’s incentive program
                               can be found at www.novozymes.com from February 8, 2008. The
                               Novozymes Report 2007 also contains a complete list of the environmental
                               and social targets.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                            Page 12 of 27

Group financial statement for 2007
Closure of sHA                 In January 2008 Novozymes announced the closure of streptococcal-based
production in China            production of hyaluronic acid (sHA) in China. As stated in the press release,
                               this decision will have no significant financial impact for Novozymes.
                               Expanding Novozymes’ business base in order to secure long-term growth
                               brings with it business risks and will at times necessitate closures such as this.




Environmental and social discussion

                              Water and energy – Effective utilization of resources
Appendix 7
                              Consumption of water and energy related to goods sold rose by 12% and
External factors
                              13% respectively in 2007 compared with 2006. Measured in local currencies,
made it difficult to
                              realized sales growth in 2007 was 14%. Target for 2007 was that comption
achieve all targets
                              should growth by minimum one procent point less than sales growth. The
                              target for energy was exceeded by a small margin.

                              Significant spills
                              There were no significant spills in 2007.

                              Occupational accidents
                              There was one serious occupational accident in 2007 – the goal was none. The
                              frequency of reported occupational accidents resulting in absence rose to 4.8
                              per million working hours in 2007 compared with 3.7 in 2006. The target for
                              2007 of keeping the frequency of occupational accidents resulting in absence
                              below 4.5 was thus not achieved. A number of activities have been initiated
                              with a view to further increasing the focus on prevention.

                              Rate of employee turnover and absence
                              The rate of employee turnover for 2007 was 9.0%, an increase of one
                              percentage point compared with 2006, and higher than the target for 2007.
                              This was due to rising demand for labor on both the Danish and American
                              labor markets. Novozymes is still considered to have a relatively low rate of
                              employee turnover.
                              The rate of absence was 2.2%, which was below the target for the year.

                              Novozymes has set a number of targets within the environmental and social
                              area for 2007 and 2008. An overview and report on progress can be found at
                              www.novozymes.com and in the Novozymes Report 2007.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                               Page 13 of 27

Group financial statement for 2007
Forward-looking statements

                              This Stock exchange announcement contains forward-looking statements,
                              including the financial outlook for 2008. Forward-looking statements are, by
                              their very nature, associated with risks and uncertainties that may cause actual
                              results to differ materially from expectations. The uncertainties may include
                              unexpected developments in the international currency exchange and
                              securities markets, market-driven price decreases for Novozymes’ products,
                              and the launch of competing products within Novozymes’ core areas.


Bagsværd, January 24, 2008

Board of Directors
Novozymes A/S




Contact persons:
Press and media:                                          Investor relations:
Annegrethe M. Jakobsen (Europe)                           Camilla Kinch Jensen
Tel. (direct): +45 4446 3050                              Tel. (direct): +45 4446 0852
Tel. (mobile): +45 3077 3050                              Tel. (mobile): +45 3077 0852

René Trondborg (Europe)                                   Ian Christensen
Tel. (direct):: +45 4446 2274                             Tel. (direct): +45 4446 0341
Mobile: +45 3077 2274                                     Tel. (mobile): +45 3077 0341

Johan Melchior                                            Tobias Bjørklund (North America)
Tel. (direct): +45 4446 0690                              Tel. (direct): +1 919 494 3483
Tel. (mobile): +45 3077 0690                              Tel. (mobile): +1 919 649 2565


Novozymes is the world leader in bioinnovation. Together with customers across a broad array of
industries we create tomorrow’s industrial biosolutions, improving our customers’ business and the
use of our planet’s resources. Read more at www.novozymes.com.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                             Page 14 of 27

Group financial statement for 2007
Statement of the Board of Directors and the Management

The Board of Directors and the Management have considered and approved the audited Group
financial statement for Novozymes A/S for 2007.

The Group financial statement has been prepared in accordance with International Financial Reporting
Standards (IAS 34), and additional Danish regulations for the presentation of group financial
statements by listed companies.

In our opinion the accounting policies used are appropriate, the Group’s internal controls relevant to
preparation and presentation of a group financial statement are adequate, and the Group financial
statement gives a true and fair view of the Group’s assets, liabilities, net profit, and financial position
at December 31, 2007, and of the results of the Group’s operations and cash flow for 2007.

Bagsværd, January 24, 2008

Management:


Steen Riisgaard                               Benny D. Loft               Per Falholt
President and CEO




Peder Holk Nielsen                            Thomas Nagy                 Thomas Videbæk




Board of Directors:


Henrik Gürtler                                Kurt Anker Nielsen                        Paul Petter Aas
Chairman                                      Vice-Chairman




Arne Hansen                                   Jerker Hartwall                           Søren Jepsen




Ulla Morin                       Walther Thygesen             Mathias Uhlén             Hans Werdelin




Novozymes A/S – Stock exchange announcement no. 1, 2008                                            Page 15 of 27

Group financial statement for 2007
Appendices
Appendix 1                Main items and key figures
                          1.1 For the fourth quarter 2007
                          1.2 For the years 2003–2007
                          Distribution of sales
Appendix 2
                          2.1 By industry
                          2.2 By geographical area
                          2.3 Quarterly sales by industry
                          2.4 Quarterly sales by geographical area
Appendix 3                Statement of cash flow and financial resources
Appendix 4                Income statement
Appendix 5                Balance sheet and Statement of shareholders’ equity
                          5.1 Balance sheet at December 31, 2007
                          5.2 Statement of shareholders’ equity 2007
                          5.3 Acquisitions
Appendix 6                New products launched in 2007
Appendix 7                Selected key figures, environmental and social data
Appendix 8                Stock exchange announcements for 2007 (excluding insider trading)
Appendix 9                Financial calendar 2008
Appendix 10               2008 and long-term sales expectations




Novozymes A/S – Stock exchange announcement no. 1, 2008                                       Page 16 of 27

Group financial statement for 2007
Appendix 1: Main items and key figures

1.1 For the fourth quarter 2007
                                                         2007      2006                 2007     2006
                                                                            % change                     % change
(DKK million)                                                                             4Q       4Q

S ales                                                  7,438     6,802          9%    1,844    1,764          5%
Gros s profit                                            3,949    3,655          8%      986       911         8%
Gros s margin                                           53.1%     53.7%                53.5%    51.6%

Operating profit                                         1,481    1,340         11%     332      334          -1%
Operating profit margin                                 19.9%     19.7%                18.0%    18.9%

                                                                                   -                             -
Net financials                                             (96)    (122)                (21)     (12)
P rofit before tax                                      1,385     1,218         14%     311      322          -4%

C orporation tax                                         (343)     (307)        12%      (79)     (82)        -4%
Net profit                                               1,042       911        14%       232     240         -3%

Attributable to:
S hareholders in the parent company                      1,048       909        15%      237      244         -3%
                                                                                                                 -
E quity minority interes ts                                 (6)       2            -      (5)      (4)


                                                                                   -                             -
F oreign exchange gain/(los s ), net                          5     (50)                  (4)       12
                                                                                   -                             -
Interes t income/(cos ts )                                 (78)     (26)                 (22)     (10)
                                                                                   -                             -
Other financial items                                      (23)     (46)                    5     (14)
Total financ ial inc ome/(c os ts )                        (96)    (122)           -     (21)     (12)           -

E arnings per DKK 10 s hare                              16.93     14.46        17%     3.85      3.94        -2%
Average no. of A/B s hares , outs tanding
(million)                                                 61.9      62.9                61.8     61.9

E arnings per DKK 10 s hare                              16.47     14.09        17%     3.76      3.84        -2%
(diluted)
Average no. of A/B s hares , diluted                      63.6      64.5                63.4     63.6
(million)

F ree c as h flow before ac quis itions                    963     1,058        -9%

R eturn on inves ted capital (R OIC ), incl. goodwill
after tax (R OIC ), incl. goodwill                      21.7%     20.2%

Net interes t-bearing debt                              (1,769)   (1,455)      -22%

E quity ratio                                           41.3%     42.6%

R eturn on equity                                       29.5%     25.4%




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                  Page 17 of 27

Group financial statement for 2007
1.2 For the years 2003-2007
                                                                      F ull year
(DKK million)                                       2007      2006           2005    2004          2003

S ales                                             7,438     6,802        6,281     5,988        5,775
- E nzymes                                          6,906     6,320        5,898    5,690        5,514
- Microorganis ms                                     308       348          308      298          261
- BP I                                                224       134           75            -            -

Gros s profit                                       3,949    3,655        3,345     3,150        2,993
Gros s margin                                      53.1%     53.7%        53.3%     52.6%        51.8%

Operating profit (E B IT)                           1,481    1,340        1,206     1,089         998
Operating profit margin                            19.9%     19.7%        19.2%     18.2%        17.3%

Net financials                                        (96)   (122)           (56)     (33)           32
P rofit before tax                                  1,385    1,218         1,150    1,056         1,030

C orporation tax                                    (343)     (307)        (289)     (281)         (284)
Net profit                                          1,042       911          861       775           746

Minority interes ts                                     6       (2)           (3)     (11)           (9)
Net profit inc luding                               1,048      909           858      764           737
minority interes ts


F oreign exchange gain/(los s ), net                    5      (50)          (7)        33            81
Interes t income/ (cos ts )                          (78)      (26)         (23)      (35)          (42)
Other financial items                                (23)      (46)         (26)      (31)           (7)
Total financ ial inc ome/(c os ts )                  (96)     (122)         (56)      (33)            32

R eturn on inves ted capital                       21.7%     20.2%        19.3%     17.4%        15.5%
after tax (R OIC )

E arnings per DKK 10 s hare                         16.93    14.46         13.10    11.19         10.45
Average no. of A/B s hares , outs tanding
(million)                                            61.9     62.9          65.5     68.3           70.5

E arnings per DKK 10 s hare                         16.47    14.09         12.79    10.95         10.39
(diluted)
Average no. of A/B s hares , diluted                 63.6     64.5          67.1     69.8           70.9
(million)

Net interes t-bearing debt                          1,769    1,455           877      638           782

E quity ratio                                      41.3%     42.6%        51.9%     55.8%        54.4%

R eturn on equity                                  29.5%     25.4%        22.2%     19.3%        18.2%




Novozymes A/S – Stock exchange announcement no. 1, 2008                                         Page 18 of 27

Group financial statement for 2007
Appendix 2: Distribution of sales
2.1 By industry
                                          2007            2006           % change
(DKK million)

E nzymes                                  6,906           6,320                 9
- detergent enzymes                       2,239           2,040                10
- technical enzymes                       2,263           1,977                14
- food enzymes                            1,699           1,603                 6
- feed enzymes                              705             700                 1
Mic roorganis ms                            308             348              (11)
BPI                                         224             134                67
S ales                                    7,438           6,802                 9



2.2 By geographical area
                                           2007            2006        % change % currency % change in
(DKK million)                                                                       impact local currency

E urope, Middle E as t & Africa           3,039            2,855              6             (1)                 7
North America                             2,412            2,066             17             (9)                26
As ia P acific                            1,466            1,401              5             (5)                10
Latin America                               521              480              9             (1)                10
S ales                                    7,438            6,802              9             (5)                14




2.3 Quarterly sales by industry
                                                                  2007                              #R E F !                     % change
(DKK million)                        4Q           3Q             2Q         1Q        4Q            3Q              2Q     1Q       4Q/4Q

E nzymes                          1,759       1,759         1,661         1,727     1,608         1,658        1,538     1,516           9
- detergent enzymes                 539         573           555           572       505           538          492       505           7
- technical enzymes                 603         581           537           542       550           505          469       453          10
- food enzymes                      428         435           402           434       374           438          404       387          14
- feed enzymes                      189         170           167           179       179           177          173       171           6
Mic roorganis ms                     62          71            91            84        81            83           90        94        (23)
BPI                                  23          30            51           120        75            15           21        23        (69)
S ales                            1,844       1,860         1,803         1,931     1,764         1,756        1,649     1,633           5




2.4 Quarterly sales by geographical area
                                                          2007                                       2006                        % change
(DKK million)                          4Q           3Q            2Q         1Q       4Q            3Q              2Q     1Q       4Q/4Q

E urope, Middle E as t & Africa        726          782        734           797      733           750          689       683         (1)
North America                          588          593        592           639      530           524          507       505         11
As ia P acific                         386          358        355           367      366           354          340       341           5
Latin America                          144          127        122           128      135           128          113       104           7
S ales                               1,844        1,860      1,803         1,931    1,764         1,756        1,649     1,633           5




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                                          Page 19 of 27

Group financial statement for 2007
Appendix 3: Statement of cash flow and financial resources
                                                                         2006
                                                                2007
(DKK million)

Net profit                                                      1,042      911
R evers als of non-cas h expens es                              1,028      996
C orporation tax paid                                           (186)    (120)
Interes t received                                                 98      133
Interes t paid                                                  (159)    (147)
C as h flow before c hange in working c apital                  1,823    1,773

C hange in working c apital
(Increas e)/decreas e in receivables                            (113)      (80)
(Increas e)/decreas e in inventories                                39     (48)
Increas e/(decreas e) in trade payables and other liabilities     (35)   (111)
C as h flow from operating ac tivities                          1,714    1,534

Inves tments
P urchas e of intangible fixed as s ets                          (14)     (13)
S ale of property, plant and equipment                              8       29
P urchas e of property, plant and equipment                     (729)    (492)
P urchas e of minority s hares                                   (16)        0
C as h flow from inves ting ac tivities before                  (751)    (476)
ac quis itions

F ree c as h flow before ac quis itions                           963    1,058

Acquis ition of activities and companies                        (716)    (477)

F ree c as h flow after ac quis itions                            247     581




Novozymes A/S – Stock exchange announcement no. 1, 2008                       Page 20 of 27

Group financial statement for 2007
Appendix 4: Income statement
                                                                              % change
                                                           2007      2006
(DKK million)                                                                      Y/Y

S ales                                                     7,438     6,802           9
C os t of goods s old                                     (3,489)   (3,147)         11
Gros s profit                                              3,949     3,655           8

S ales and dis tribution cos ts                            (921)     (844)           9
R es earch and development cos ts                          (995)     (880)          13
Adminis trative cos ts                                     (675)     (650)           4
Other operating income, net                                  123        59         108
Operating profit                                           1,481     1,340          11

F inancial income                                            130       134         (3)
F inancial cos ts                                          (226)     (256)        (12)
P rofit before tax                                         1,385     1,218          14

C orporation tax                                           (343)     (307)          12
Net profit                                                 1,042       911          14

Attributable to:
S hareholders in the parent company                        1,048       913
Minority interes ts                                           (6)       (2)




Novozymes A/S – Stock exchange announcement no. 1, 2008                                  Page 21 of 27

Group financial statement for 2007
Appendix 5: Balance sheet and statement of shareholders’ equity

5.1 Balance sheet at December 31, 2007

Assets                                                    2007    2006
(DKK million)                                              End     End

Completed IT development projects                            24     39
Acquired patents, licenses and know-how                     766    497
Goodwill                                                    500    216
IT development projects in progress                          31     17
Intangible fixed assets                                   1,321    769

Land and buildings                                        1,729   1,723
Production equipment and machinery                        1,129   1,012
Other equipment                                             307     319
Property, plant and equipment under construction            677     499
Property, plant and equipment                             3,842   3,553

Deferred tax assets                                         47      45

Non-current financial assets (non-interest-bearing)          8      12

Total fixed assets                                        5,218   4,379

Raw materials and consumables                               251     201
Goods in progress                                           317     338
Finished goods                                              754     787
Inventories                                               1,322   1,326

Trade receivables                                         1,344   1,193
Tax receivable                                              207     248
Other receivables                                           124     145
Receivables                                               1,675   1,586

Financial assets (interest-bearing)                        116     133
Financial assets (non-interest-bearing)                     80      44
Total financial assets                                     196     177

Cash at bank and in hand                                   460     497

Total current assets                                      3,653   3,586

Total assets                                              8,871   7,965




Novozymes A/S – Stock exchange announcement no. 1, 2008                   Page 22 of 27

Group financial statement for 2007
Liabilities and shareholders' equity                                2007             2006
(DKK million)                                                        End              End

Share capital                                                         650               650
Treasury shares                                                   (1,837)           (1,449)
Other reserves                                                         23                86
Retained earnings                                                   4,821             4,072
Minority interests                                                     10                34
Total shareholders' equity                                          3,667             3,393

Deferred tax liabilities                                              939              756
Long-term employee benefits                                            16               15
Non-current provisions                                                131              134
Non-current financial liabilities (interest-bearing)                1,545            1,637
Non-current financial liabilities (non-interest-bearing)              158               71
Other non-current liabilities (interest-bearing)                       21               21
Total non-current liabilities                                       2,810            2,634

Financial liabilities (interest-bearing)                              779              426
Financial liabilities (non-interest-bearing)                           35               33
Provisions                                                             84               20
Trade payables                                                        422              386
Tax payable                                                            49               50
Other current liabilities                                           1,025            1,023
Total current liabilities                                           2,394            1,938

Total liabilities                                                   5,204            4,572

Total liabilities and shareholders' equity                          8,871            7,965



5.2 Statement of shareholders’ equity 2007
                                                           2007             2006
(DKK million)
S hareholders ' equity exc l. minority interes ts –
beginning of period                                        3.359           3.761
Net profit                                                 1.048             909
Dividend paid                                              (278)           (255)
P urchas e of treas ury s hares , net                      (388)           (996)
C urrency trans lation of net as s ets , etc.                (84)            (60)
S hareholders ' equity exc l. minority interes ts          3.657           3.359

Minority interes ts – beginning of period                     34              33
Net profit                                                   (6)                2
Dividend paid                                                (1)              (1)
C urrency trans lation of net as s ets , etc.                (1)              (1)
C hange in minority interes ts                              (16)                3
Minority interes ts – end of period                           10              34

Total equity – end of period                               3.667           3.393




Novozymes A/S – Stock exchange announcement no. 1, 2008                                       Page 23 of 27

Group financial statement for 2007
5.3 Acquisitions

                                                              B ioc on                         P hilom B ios Inc .                         I alt
                                                   C arrying         F air value on       C arrying       F air value on       C arrying         F air value on
                                                amount prior             date of       amount prior           date of       amount prior             date of
                                                to acquis ition       acquis ition     to acquis ition     acquis ition     to acquis ition       acquis ition

The as s ets and liabilities aris ing from acquis itions are as follows :

Intangible as s ets                                         -                  318                  1                 59                  1                377
P roperty, plant and equipment                                 7                  9                37                 37                 44                 46
Inventories                                                  23                 29                 21                 24                 44                 53
R eceivables and prepayments                                 40                 40                  7                  7                 47                 47
C as h and cas h equivalents                                -                  -                    8                  8                  8                  8
Liabilities                                                   (9)                (9)              (34)               (55)               (43)               (64)
Ac quired net as s ets                                       79                405                108                190                187                595

Goodwill of acquis itions                                                      200                                   (71)                                  129
Total purc has e pric e                                                        605                                   119                                   724

Les s :
C as h and cas h equivalents in acquired companies                             -                                       8                                     8
C as h flow from ac quired c ompanies                                          605                                   111                                   716

The acquired as s ets and goodwill compris e the following:

C as h cons ideration                                                          593                                   116                                   709
Directs cos ts attributable to the acquis itions                                12                                     3                                    15
Totan purc has e pric e                                                        605                                   119                                   724

F air value of acquired as s ets                                               405                                   190                                   595
Goodwill                                                                       200                                   (71)                                  129


Biocon
On October 1, 2007 Novozymes purchased the activities in the enzyme part of Biocon Limited. The total purchase price was DKK 605 million
including discount of future payments for obtaining certain business targets.


The fair value figures are to a certain extent based on fair values made by an external assessor, but a few items are estimated in the light of
information and subsequent changes can appear if new information appears.


Philom Bios Inc.
On December 10, 2007 Novozymes purchased the share in Philom Bios Inc. The total purchase price was DKK 119 million.


The fair values in Philom Bios Inc. is based on a provisional value because it was not possible to finish the valuation before the preparation of
the annual report due to the short time Novozymes has owned the company.


Goodwill represents the difference between the value of the acquired companies and the value allocated to the specific net assets. Hence,
goodwill represents assets for which a value cannot be measured reliably, including early-stage research projects and expected synergies
arising in connection with the fusion of the existing business.
The purchased companies enter into the Income statement for 2007 with sales of DKK 20 million and a minor loss. It has not been possible
to enlighten the combined sales and result from the beginning of the year as their accounting year and accounting policies have not been
following the policies of the Novozymes Group together with the fact that an individual report for Biocon’s enzyme activitiy has not been
prepared as they are entered into an integrated part of the Biocon group.




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                                                             Page 24 of 27

Group financial statement for 2007
Appendix 6: New products launched in 2007

                                    ®
                    Mannaway , an enzyme for the detergent indus try des igned to remove mannan-containing
1Q 2007
                    s tains

                                    ®
                    Vis coferm , an enzyme for the alcohol indus try reducing vis cos ity as well as water and
1Q 2007
                    energy cons umption in the production proces s

                                ®
1Q 2007             HyaC are , an optimized hyaluronic acid for eyecare in the medical device market

                                    ®
                    S tainzyme P lus , a detergent enzyme with improved was hing characteris tics at low
2Q 2007
                    temperatures

                            ®
                    Ultraflo Max, an enzyme for the brewing indus try which allows a long and cons is tent
2Q 2007
                    filtration proces s and therefore an optimized production proces s

                                ®
                    S aczyme , a cos t-effective enzyme for the alcohol indus try us ed to convert raw materials
2Q 2007
                    into fermentable s ugars

                                    ®
                    R onozyme NP , an improved enzyme for the feed indus try us ed to releas e naturally
2Q 2007
                    occurring phos phate in feed for pigs and poultry

                                ®
                    S pirizyme Ultra, an enzyme us ed in the conventional convers ion of corn to bioethanol to
2Q 2007
                    increas e yields

                                    ®
                    Acrylaway , an enzyme for the food indus try us ed to reduce the level of acrylamide in food
3Q 2007
                    products

4Q 2007             S ucrozyme, an enzyme for the food indus try us ed to manufacture s weeteners




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                   Page 25 of 27

Group financial statement for 2007
Appendix 7: Selected key figures, environmental and social data
                                                                                  2007        2006 % change


Water cons umption (related to goods s old), 1,000 m³                            5.439        4.871      12
E nergy cons umption, 1,000 GJ                                                   3.745        3.307      13
S ignificant s pills                                                                 -            -

F atalities                                                                               -          -
F requency of occupational accidents pr. million working hours                         4,8        3,7

E mployees at December 31, 2007                                                  4.933        4.544       9
R ate of employee turnover                                                       9,0%         8,0%
R ate of abs ence                                                                2,2%         2,3%




Appendix 8: Stock exchange announcements for 2007
 E xcluding ins iders ' trading


 J anuary 25, 2007                Group financial s tatement for 2006

 F ebruary 19, 2007               Novozymes awarded damage payment for patent infringement

 March 9, 2007                    Annual Meeting of S hareholders 2007

 April 3, 2007                    C hange in revenue reporting

 April 17, 2007                   Novozymes terminates patent infringement s uit

 April 25, 2007                   Group financial s tatement, firs t quarter of 2007

 J uly 18, 2007                   Novozymes to acquire the enzyme bus ines s of Biocon, India

 Augus t 9, 2007                  Group financial s tatement for firs t half of 2007

 Augus t 28, 2007                 C hanges in Novozymes ' E xecutive Managment as of October 1, 2007

 October 1, 2007                  Acquis ition of enzyme activities from Biocon completed

 October 25, 2007                 Group financial s tatement for the firs t nine months of 2007

 October 31, 2007                 Novozymes to acquire P hilom Bios Inc., C anada

 December 10, 2007                P hilom Bios acquis ition completed




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                       Page 26 of 27

Group financial statement for 2007
Appendix 9: Financial calendar 2008


March 5, 2008                 Annual Meeting of S hareholders

April 24, 2008                Group financial s tatement for firs t quarter of 2008

Augus t 14, 2008              Group financial s tatement for firs t half of 2008

October 31, 2008              Group financial s tatement for firs t nine months of 2008




Appendix 10: 2008 and long-term sales expectations
                                     E xpec ted growth                                R ealized growth

                                                                                                         C AGR (LC Y)
                         Long-term (LC Y)     2008 (DKK)   2008 (LC Y) F Y07 (DKK)    F Y07 (LC Y)
                                                                                                           (2003-07)


Detergent enzymes              3-5%               ~4%         ~5%           10%            12%               3%



Technical enzymes            15-18%             20-25%      25-30%          14%            22%              16%



F ood enzymes                 ~10%               2-7%        5-10%           6%             9%               6%



F eed enzymes                 5-10%               ~0%         ~0%            1%             5%               6%



Microorganis ms                10%              10-20%      20-30%          -11%            -5%              9%


Biopharmaceutical
                             10-15%              ~(20)%     ~(15)%          67%            64%               NA
ingredients


Total s ales                  8-10%              8-11%      11-14%           9%            14%               8%




Novozymes A/S – Stock exchange announcement no. 1, 2008                                                       Page 27 of 27

Group financial statement for 2007

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Novoenzymes Group Financial Statement2007

  • 1. GROUP FINANCIAL STATEMENT FOR 2007 January 25, 2008 2007 was a really good year for Novozymes. Growth was the theme of the year, with sales growth higher than expected at 14%. The financial results were satisfactory, particularly in the light of high energy and raw material prices. Unfavorable exchange rate movements had a negative impact on the results measured in DKK. Growth in earnings was 11%, and free cash flow was DKK 963 million. The high rate of sales growth is expected to continue in 2008 and onwards, and therefore it has been decided to expand the production in the USA. • Novozymes’ sales rose by 14% in local currencies in 2007. Measured in DKK sales rose by 9% to DKK 7,438 million from DKK 6,802 million in 2006. Growth excluding acquisitions was 12% • Operating profit rose by 11% to DKK 1,481 million in 2007 from DKK 1,340 million in 2006. One-off items (cf. Stock exchange announcement no. 14/2007) had a positive impact of approximately DKK 75 million. Operating profit excluding one-off items rose by 5%. The operating profit margin including one-off items was 19.9% against 19.7% in 2006 • Net financial costs were DKK 96 million against DKK 122 million in 2006 • Net profit for the period rose by 14% to DKK 1,042 million in 2007 against DKK 911 million in 2006. Growth excluding one-off items was 8% • Earnings per share (diluted) for 2007 were DKK 16.47, an increase of 17% • Free cash flow before acquisitions was DKK 963 million against DKK 1,058 million in 2006 • Return on invested capital (ROIC) rose to 21.7% from 20.2% in 2006 Outlook for 2008 Assuming that exchange rates for the company’s key currencies remain at the spot rates on January 23, 2008, expected outlook for 2008 is as follows (excluding one-off items in 2007): • Growth in sales of 11–14% in local currencies and 8–11% in DKK • Growth in operating profit of 2–5% • Growth in net profit of 4–7% • Investment before acquisitions of DKK 800-950 million • Free cash flow before acquisitions of DKK 750–900 million The Board of Directors will recommend a dividend for 2007 of DKK 5.00 per share at the Annual Meeting of Shareholders on March 5, 2008. Stock exchange announcement no. 1, 2008 Side 1 af 27 Novozymes A/S Krogshøjvej 36 Telephone: Internet: Investor Relations 2880 Bagsværd +45 4446 0000 www.novozymes.com 2008-01809-01 Denmark Fax: CVR number: +45 4446 1002 10 00 71 27
  • 2. “2007 was a really good year for Novozymes,” says Steen Riisgaard, President and CEO. “Sales growth has never been higher. We had success almost everywhere, so growth was higher than expected. The financial results met expectations despite rising raw material and energy prices and the declining US dollar, so we are extremely pleased.” And he continues: “We expect growth to remain high in 2008 and this means – together with the strong political support for bioethanol production in the USA – that we are increasing our expectation for long-term growth. Given this outlook, we will build more capacity in the USA, simply to keep up with the growth.” Long-term expectations Novozymes increases its outlook for long-term organic growth from 8–9% to 8-10%. This reflects our expectations of higher growth rates the coming years, but also a greater uncertainty in future estimates. Underlying growth expectations for some industries have changed, especially upwards adjustments for technical and detergent enzymes. On this background, among other, it has been decided to build a new enzyme plant in the USA. A total investment of DKK 300-500 million in 2009-2010 is expected. Income statement and balance sheet Appendices 1 & 2 Sales Sales rose by 14% in local currencies in 2007. Measured in DKK sales were 14% growth in DKK 7,438 million against DKK 6,802 million in 2006, an increase of 9%. sales, of which two Exchange rate movements for the company’s key currencies had a negative percentage points impact on sales in DKK of five percentage points. from acquisitions Acquired activities impacted sales positively. Excluding acquisitions, organic growth in sales in local currencies was 12% in 2007. Sales in DKK million Distribution of sales 3% 4% 10% Detergent enzymes 30% 7,438 Technical enzymes 6,802 Food enzymes 23% Feed enzymes Microorganisms 30% BPI 2006 2007 Seen in isolation, sales in the fourth quarter of 2007 rose by 9% in local currencies and 5% in DKK compared with 2006. Average exchange rates for the company’s key currencies were lower in the fourth quarter of 2007 than in the same period of 2006. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 2 of 27 Group financial statement for 2007
  • 3. Sales in i DKK million 2,263 2,239 2,040 1,977 1,699 1,603 705 700 134 348 308 224 Detergent enzymes Technical enzymes Food enzymes Feed enzymes M icroorganisms BPI 2006 2007 Sales of enzymes Enzymes rose by 14%; the Growth in local currencies was 14% in 2007, while sales of enzymes in DKK weak US dollar rose by 9% to DKK 6,906 million from DKK 6,320 million in 2006. Exchange reduced growth in rate movements had a negative effect on sales in DKK. DKK Sales of enzymes in the fourth quarter of 2007 rose by 15% in local currencies and 9% in DKK compared with the same period of 2006. Sales generated by the activities acquired from Biocon Limited were approximately DKK 20 million in the quarter. 12% growth in sales Sales of detergent enzymes rose by 12% in local currencies and 10% in DKK of detergent compared with 2006. Throughout the year the high level of growth was enzymes driven first and foremost by rising demand and an increased market share in Europe. However, developments on the American and Asian markets also contributed to the positive trend in 2007 compared with previous years. Sales of detergent enzymes in the fourth quarter rose by 9% in local currencies and 7% in DKK. Over 40% growth in Sales of technical enzymes rose by 22% in local currencies and 14% in DKK enzymes for in 2007. Growth in DKK was particularly affected by the negative trend in the bioethanol US dollar. There was good growth in all industries other than the textile industry. Sales of enzymes for bioethanol rose by more than 40% in 2007 to DKK 1 billion, equivalent to approximately 13% of Novozymes’ total sales. The year’s Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 3 of 27 Group financial statement for 2007
  • 4. growth was driven by the increase in bioethanol production in the USA and strengthening of Novozymes’ market position. There was an increase in sales to textile mills, but lower sales to the denim segment as a result of a change in fashion trends. Total sales to the textile industry ended 2% lower in local currencies than in 2006. Taking the fourth quarter of 2007 in isolation, sales of technical enzymes rose by 19% in local currencies and 10% in DKK compared with the same period of 2006. This trend was primarily due to increased sales of enzymes for bioethanol production. 9% growth in sales Sales of food enzymes rose by 9% in local currencies and 6% in DKK in of food enzymes 2007. This growth can mainly be attributed to increased penetration of fresh- keeping enzymes in the baking industry in Europe. There was also increased use of enzymes in the brewing industry, as a result of rising ingredient prices coupled with a decline in quality. Positive effect from Sales in the fourth quarter rose by 19% in local currencies and 14% in DKK activities acquired in compared with the same period in 2006. The trend for the quarter was India positively affected by the acquired activities from Biocon Limited, as well as comparison with a weak quarter in 2006. Growth in sales of Sales of feed enzymes rose by 5% in local currencies and 1% in DKK in 2007. feed enzymes Sales were negatively affected by lower exchange rates. There was growth in despite lower prices sales of enzymes for plant proteins but total growth was reduced by low in the market volume growth and lower prices for phytase products. Seeing the fourth quarter of 2007 in isolation, sales in local currencies rose by 11% and 6% in DKK. Ronozyme® NP, which was recently launched in the American and Asian markets, had a positive impact on the quarter’s results. There was also a small positive effect from the acquisition of Biocon Limited’s enzyme activities. Microorganisms Low sales within Sales of microorganisms in 2007 were a disappointing 5% lower in local institutional and currencies than in 2006. Measured in DKK sales were 11% lower as a result household cleaning of the unfavorable trend in the US dollar. This business area accounts for a high proportion of sales on the US market. 2007 saw the discontinuation of an unprofitable product line, which, as expected, has had a negative effect on sales growth as well as reducing Novozymes’ market share. Growth in sales of microorganisms for wastewater treatment and plant care was unable to counteract the effect of lower sales than expected within institutional and household cleaning. The purchase of the Canadian company Philom Bios Inc. was completed in December 2007. Sales from this acquisition will not impact sales of microorganisms until 2008. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 4 of 27 Group financial statement for 2007
  • 5. Biopharmaceutical ingredients (BPI) Expected growth in Sales of biopharmaceutical ingredients in 2007 rose to DKK 224 million BPI compared with DKK 134 million in 2006, an increase of 67%. Measured in local currencies the increase was 64%. Acquisitions in 2006 had a positive impact of approximately DKK 118 million on sales for the year. Taking the fourth quarter of 2007 in isolation, sales of biopharmaceutical ingredients were DKK 23 million against DKK 75 million in the same period of 2006. This development is due partly to an anticipated decline in contract volumes, together with a change in the quarterly sales distribution during 2007 compared with 2006. As noted previously, this industry is subject to substantial quarterly variation in sales patterns, as sales are generally composed by a small number of relatively large transactions. Sales by geographical area 5% (10%) 20% 6% (7%) 9% (10%) Europe/MEA 41% North America 7% Latin America Asia 17% (26%) 32% Growth in DKK/(Growth in local currency) Sales in Europe/MEA rose by 7% in local currencies and 6% in DKK. Growth for the year was primarily driven by increased sales of enzymes for the detergent and baking industries. The fourth quarter ended lower than the fourth quarter of 2006 as a result of low sales within biopharmaceutical ingredients and feed enzymes. Enzymes for Sales in North America in 2007 rose by 26% in local currencies and 17% in bioethanol drive DKK. This positive trend was mainly due to sales of enzymes for bioethanol high growth in production, plus the effect of the activities acquired within biopharmaceutical North America Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 5 of 27 Group financial statement for 2007
  • 6. ingredients (BPI). The fourth quarter of 2007 also saw growth in detergent enzymes, while the development in sales of microorganisms and BPI reduced overall growth for the quarter. Sales to Latin America rose by 10% in local currencies and 9% in DKK in 2007. Growth for the year was driven by sales of detergent and feed enzymes, as well as enzymes for the brewing industry. Double-digit sales Sales in Asia rose by 10% in local currencies and 5% in DKK. There was growth in Asia general double-digit growth in most industries, but growth within enzymes for the detergent and brewing industries, and feed enzymes was particularly significant. The fourth quarter was positively affected by the enzyme activities acquired in India, and high sales of the newly launched feed enzyme Ronozyme® NP. Appendix 6 New products 10 new products One new enzyme product was launched in the fourth quarter of 2007: launched in 2007, • the highest number Sucrozyme, an enzyme for the food industry used to manufacture ever sweeteners This means that a total of 10 new products were launched in 2007, the highest number ever. Around 25% of enzyme sales in 2007 related to products launched in the last five years. Appendices 1 & 4 Costs, License fees and Other operating income Total costs excluding net financials and tax rose by 10% in 2007 to DKK 6,080 million from DKK 5,521 million in 2006. This increase was primarily related to higher sales in 2007, together with the effects of the increased level of activity from acquisitions and within research. Productivity Cost of goods sold rose by 11% in 2007 compared with 2006. This trend was improvements mainly driven by increased sales within both enzymes and biopharmaceutical reducing effect of ingredients. Productivity improvements reduced the negative effects of higher higher energy and energy and raw material prices on the cost level. raw material prices The gross margin for 2007 was 53.1% against 53.7% in 2006. The main Gross margin on a reasons for the lower gross margin were a relatively low margin on the sale of par with 2006, products from activities acquired in 2006 plus lower exchange rates through adjusted for 2007, particularly for the USD and JPY. The gross margin for 2007 is on a par currency effect and with 2006 when adjusted for the negative currency effect and the lower acquisitions margin on sales of products from acquired activities in 2006 – despite higher raw material prices. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 6 of 27 Group financial statement for 2007
  • 7. Other operating costs rose by 9% to DKK 2,591 million for 2007. This increase was due primarily to rising sales and acquired activities. Costs of sales, distribution and business development rose by 9%, representing 12% of sales. Research and development costs rose by 13%, representing 13% of sales, while there was an increase of 4% in administrative costs in 2007. Other operating income was DKK 123 million in 2007 against DKK 59 million in 2006. The main reason for this increase was one-off items of approximately DKK 75 million in the second quarter of 2007. Depreciation and amortization charges rose by 4% to DKK 490 million from DKK 469 million in 2006. This increase was primarily related to acquired activities. Operating profit Appendix 1 11% growth in Operating profit margin % operating profit – Operating profit in DKK million 5% adjusted for one-off items 1,481 19.9 1,340 19.7 2006 2007 2006 2007 Operating profit rose to DKK 1,481 million in 2007 from DKK 1,340 million in 2006, an increase of 11%. This result incorporates a positive one-off effect of approximately DKK 75 million. Adjusted for this, growth in operating profit was 5%. Growth was reduced by lower exchange rates, particularly for the USD and JPY, and a lower margin on sales from activities acquired in 2006. The operating profit margin, expressed as operating profit as a percentage of High earnings level sales, was 19.9% for 2007 against 19.7% in 2006. Excluding one-off items, when adjusted for the operating profit margin was 18.9%. Taking the fourth quarter in currency isolation, the operating profit margin was reduced by more than one percentage point compared with 2006 as a result of negative exchange rate movements. Adjusted for the currency effect and one-off items, the operating profit margin for the year as a whole was on a par with 2006. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 7 of 27 Group financial statement for 2007
  • 8. Net financial items Net foreign Net financial costs for 2007 fell to DKK 96 million against DKK 122 million in exchange gain 2006. The main reason for the lower cost level in 2007 was a net foreign reduces net financial exchange gain of DKK 5 million, whereas there was a net foreign exchange costs for 2007 loss of DKK 50 million in 2006. Net interest expenses in 2007 were higher than in 2006. This can be attributed to higher interest rates and debt, plus the fact that net interest expenses in 2006 were positively affected by tax- related non-recurring income but negatively affected by the fact that the acquisition of Biocon Limited’s enzyme activities resulted in higher interest expenses in the fourth quarter of 2007. Net interest-bearing debt was DKK 1,769 million in 2007 against DKK 1,455 million in 2006. Appendix 1 Profit before tax and net profit for the period Profit before tax rose by 14% to DKK 1,385 million from DKK 1,218 million 14% growth in net in 2006. Adjusted for one-off items, growth in profit before tax was 8%. profit for the year Net profit for 2007 was DKK 1,042 million against DKK 911 million in 2006, an increase of 14%. Net profit for the year was positively affected by one-off items and a reduction in Danish corporation tax. Appendix 3 Cash flow, investments and acquisitions Free cash flow before acquisitions was DKK 963 million in 2007 against Increase in free cash DKK 1,058 million in 2006. The reduction in free cash flow was primarily due flow when adjusted to a higher level of investment in 2007. There was also a positive effect from for increased level of tax-related one-off items in 2006. investment Cash flow from operating activities increased in 2007 as a result of increased sales, which, together with ongoing optimizations, had a positive impact on inventories. High level of Net investments before acquisitions rose to DKK 735 million from DKK 476 investment in 2007, million in 2006, slightly over the level expected for 2007. Investments were among others, as a made in a bioethanol customer service center in the USA, completion of result of increased cGMP production facilities in Sweden, and new research facilities in Denmark research efforts and and India, among other. Growth in sales also meant pressure on production high level of capacity, resulting in a slight increase in the ongoing optimization bioethanol activity investments, and investment in the expansion of production announced for China already being initiated in the fourth quarter of 2007. Novozymes completed the acquisition of Philom Bios Inc. on December 10, 2007. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 8 of 27 Group financial statement for 2007
  • 9. Appendix 1 Return on invested capital The return on invested capital after tax (ROIC) rose to 21.7% against 20.2% ROIC of 21.7% in 2006. Adjusted for one-off items, ROIC in 2007 was 20.5%. Appendix 5 Balance sheet and Statement of shareholders’ equity Shareholders’ equity was DKK 3,667 million at December 31, 2007, against Equity represents DKK 3,393 million at January 1, 2007. Shareholders’ equity was increased by 41% of the balance net profit for the period but reduced by currency translation adjustments in sheet total respect of subsidiaries’ net assets, dividend payments, and purchase of treasury shares. Shareholders’ equity represented 41.3% of the balance sheet total at December 31, 2007. A dividend of DKK 278 million was paid for 2006. Purchase of treasury shares, reduced by exercise of stock options, decreased shareholders’ equity by DKK 778 million. At December 31, 2007, the holding of treasury shares was 3.2 million B shares, equivalent to 4.9% of the share capital. IAS 34 Accounting policies The financial statement for the fourth quarter of 2007 has been prepared in accordance with IAS 34 and the additional Danish regulations for the presentation of quarterly financial statements by listed companies. The financial statement follows the same accounting policies as the Group financial statement for 2006. Outlook Outlook for 2008 The spot rates on January 23, 2008, for the company’s key currencies were lower relative to the DKK than the average rates in 2007. If rates remain at their current levels for the rest of 2008, the average rates for 2008 will be lower than the average rates for 2007. (DKK) US D JPY C NY Average exchange rate 2007 544 4.62 71.53 S pot rate J anuary 23, 2008 511 4.85 70.69 C hange in es timated average exchange rate for 2008* -6% 5% -1% compared with average exchange rate in 2007 *E s timated average exchange rate for 2008 = s pot rate J anuary 23, 2008 Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 9 of 27 Group financial statement for 2007
  • 10. Novozymes expects high sales growth in local currencies to continue in 2008, at around 11-14%. High raw material and energy prices, and a lower US dollar rate, present challenges to the financial results. The general level of activity and investments will increase compared with 2007 as a result of continued high growth and the focus on long-term growth. These expectations are based on exchange rates remaining at their current Sales levels for the rest of 2008, particularly the EUR, USD, JPY, and CNY. In greater detail, the outlook is as follows: Growth of 11–14% in local currencies and 8–11% in DKK New products Launch of 6–8 new products in 2008 Operating profit Growth of 2–5% excluding one-off items in 2007 Operating profit margin A 5% change in the exchange rate for the USD is expected to have an impact on operating profit in 2008 of DKK 40–60 One-off items approximately DKK 75 million of the operating profit in 2007 Operating profit margin of around 18% Net profit for the year Growth in net profit of 4–7% excluding one-off items in 2007 Investments One-off items approximately DKK 56 million of the net profit in 2007 Investments before acquisitions of DKK 800–950 million Free cash flow The level of investment in 2008 is thus expected to exceed the level for 2007, primarily as a result of the expansion of enzyme production in China and further investments in research facilities in Denmark and the USA The building of a new enzyme factory in the USA is expected to have an impact on the investment level in 2009-2010 of DKK 300-500 million in total. In 2008 expectations of minor preparatory costs have been included Free cash flow of DKK 750–900 million ROIC Return on invested capital after tax (ROIC) of around 20% Acquisition effects The following acquisition effects have been incorporated in the outlook for 2008: Enzyme activities from Biocon Limited: impact on sales of enzymes Q1–Q3 of DKK 70–80 million, impact on operating profit for 2008 of approximately DKK 0 million. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 10 of 27 Group financial statement for 2007
  • 11. Philom Bios Inc.: impact on sales of microorganisms Q1–Q4 of approximately DKK 70 million, season in sales focused around Q2, impact on operating profit for 2008 of approximately DKK 0 million. Long-term expectations Total sales growth of 8-10% in local currencies, all segments included. Distribution per industry is specified in Appendix 10. Long-term financial targets Novozymes maintains its long-term financial targets. “10 in 10” – In 2005 Novozymes launched a strategic initiative with the focus on sales of DKK 10 accelerating top-line growth. As well as further investments in market- billion in 2010 expanding activities and acquisitions, the initiative included a vision of sales possible of DKK 10 billion in 2010 – “10 in 10” – which has been incorporated in the stock option programs for the Executive Management and other employees. Operating profit Annual growth in operating profit of at least 10% Operating profit Operating profit margin of around 17% margin ROIC Annual return on invested capital after tax of at least 15% Capital structure In 2007 Novozymes purchased treasury shares worth DKK 500 million, corresponding to the total approved framework for share buy-backs in 2007. The capital adjustment program started in 2004 was completed, as planned, at the end of 2007. A total of DKK 3.5 billion of the total approved Share buy-back framework of DKK 4 billion was used for share buy-backs in the period. The program completed program target of reducing the equity ratio to approximately 45% was in 2007 achieved in 2006, and at the end of 2007 the equity ratio was 41%. No further share buy-backs are planned for the current year. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 11 of 27 Group financial statement for 2007
  • 12. Pay-out ratio of At the Annual Meeting of Shareholders on March 5, 2008, the Board of 31% for 2007 Directors will recommend payment of a dividend of DKK 5.00 per share for the 2007 financial year, an increase of 11% compared with 2006. In accordance with the established dividend policy of repaying approximately 30% of net profit for the year, the dividend rate for 2007 is 31.2% against 30.5% for 2006. Events after the end of the year Partial fulfillment of Novozymes achieved the financial targets set for the 2007 employee stock targets in 2007 option program, but not all the non-financial targets. The Board has incentive programs therefore approved a 95% allocation of the stock options for the year. The same applies to partial achievement of non-financial targets in the Executive Management’s incentive program for 2007. Executive Management met 100% of its profit target for 2007, and thereby achieved 95% allocation of the maximum possible number of stock options. Executive At the Annual Meeting of Shareholders on March 5, 2008, the Board of Management’s Directors will submit for approval the general guidelines for the Executive 2008 incentive Management’s incentive program. The guidelines conform to those program previously submitted and approved for the incentive program for the period 2007–2010. As such, and assuming the guidelines are approved, the Executive Management’s stock option program will be based on two financial targets and several non-financial targets, plus fulfillment of Novozymes’ ambition of achieving sales of DKK 10 billion in 2010. The exercise price is calculated on the basis of the average closing price on the OMX Nordic Exchange Copenhagen A/S on the first five trading days after publication of the financial statements for 2007. The underlying number of stock options in the program follows from this. The stock options have a qualifying period of one year and a vesting period of three years followed by an exercise period of five years. Based on the current basic salaries paid to the Executive Management, the maximum total value of the program for 2008 according to the Black-Scholes model will be DKK 29.9 million. The stock option program will be accrued and expensed over four years, corresponding to the program’s service period. The carrying amount for 2008 is approximately DKK 8 million. The proposed guidelines for the Executive Management’s incentive program can be found at www.novozymes.com from February 8, 2008. The Novozymes Report 2007 also contains a complete list of the environmental and social targets. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 12 of 27 Group financial statement for 2007
  • 13. Closure of sHA In January 2008 Novozymes announced the closure of streptococcal-based production in China production of hyaluronic acid (sHA) in China. As stated in the press release, this decision will have no significant financial impact for Novozymes. Expanding Novozymes’ business base in order to secure long-term growth brings with it business risks and will at times necessitate closures such as this. Environmental and social discussion Water and energy – Effective utilization of resources Appendix 7 Consumption of water and energy related to goods sold rose by 12% and External factors 13% respectively in 2007 compared with 2006. Measured in local currencies, made it difficult to realized sales growth in 2007 was 14%. Target for 2007 was that comption achieve all targets should growth by minimum one procent point less than sales growth. The target for energy was exceeded by a small margin. Significant spills There were no significant spills in 2007. Occupational accidents There was one serious occupational accident in 2007 – the goal was none. The frequency of reported occupational accidents resulting in absence rose to 4.8 per million working hours in 2007 compared with 3.7 in 2006. The target for 2007 of keeping the frequency of occupational accidents resulting in absence below 4.5 was thus not achieved. A number of activities have been initiated with a view to further increasing the focus on prevention. Rate of employee turnover and absence The rate of employee turnover for 2007 was 9.0%, an increase of one percentage point compared with 2006, and higher than the target for 2007. This was due to rising demand for labor on both the Danish and American labor markets. Novozymes is still considered to have a relatively low rate of employee turnover. The rate of absence was 2.2%, which was below the target for the year. Novozymes has set a number of targets within the environmental and social area for 2007 and 2008. An overview and report on progress can be found at www.novozymes.com and in the Novozymes Report 2007. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 13 of 27 Group financial statement for 2007
  • 14. Forward-looking statements This Stock exchange announcement contains forward-looking statements, including the financial outlook for 2008. Forward-looking statements are, by their very nature, associated with risks and uncertainties that may cause actual results to differ materially from expectations. The uncertainties may include unexpected developments in the international currency exchange and securities markets, market-driven price decreases for Novozymes’ products, and the launch of competing products within Novozymes’ core areas. Bagsværd, January 24, 2008 Board of Directors Novozymes A/S Contact persons: Press and media: Investor relations: Annegrethe M. Jakobsen (Europe) Camilla Kinch Jensen Tel. (direct): +45 4446 3050 Tel. (direct): +45 4446 0852 Tel. (mobile): +45 3077 3050 Tel. (mobile): +45 3077 0852 René Trondborg (Europe) Ian Christensen Tel. (direct):: +45 4446 2274 Tel. (direct): +45 4446 0341 Mobile: +45 3077 2274 Tel. (mobile): +45 3077 0341 Johan Melchior Tobias Bjørklund (North America) Tel. (direct): +45 4446 0690 Tel. (direct): +1 919 494 3483 Tel. (mobile): +45 3077 0690 Tel. (mobile): +1 919 649 2565 Novozymes is the world leader in bioinnovation. Together with customers across a broad array of industries we create tomorrow’s industrial biosolutions, improving our customers’ business and the use of our planet’s resources. Read more at www.novozymes.com. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 14 of 27 Group financial statement for 2007
  • 15. Statement of the Board of Directors and the Management The Board of Directors and the Management have considered and approved the audited Group financial statement for Novozymes A/S for 2007. The Group financial statement has been prepared in accordance with International Financial Reporting Standards (IAS 34), and additional Danish regulations for the presentation of group financial statements by listed companies. In our opinion the accounting policies used are appropriate, the Group’s internal controls relevant to preparation and presentation of a group financial statement are adequate, and the Group financial statement gives a true and fair view of the Group’s assets, liabilities, net profit, and financial position at December 31, 2007, and of the results of the Group’s operations and cash flow for 2007. Bagsværd, January 24, 2008 Management: Steen Riisgaard Benny D. Loft Per Falholt President and CEO Peder Holk Nielsen Thomas Nagy Thomas Videbæk Board of Directors: Henrik Gürtler Kurt Anker Nielsen Paul Petter Aas Chairman Vice-Chairman Arne Hansen Jerker Hartwall Søren Jepsen Ulla Morin Walther Thygesen Mathias Uhlén Hans Werdelin Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 15 of 27 Group financial statement for 2007
  • 16. Appendices Appendix 1 Main items and key figures 1.1 For the fourth quarter 2007 1.2 For the years 2003–2007 Distribution of sales Appendix 2 2.1 By industry 2.2 By geographical area 2.3 Quarterly sales by industry 2.4 Quarterly sales by geographical area Appendix 3 Statement of cash flow and financial resources Appendix 4 Income statement Appendix 5 Balance sheet and Statement of shareholders’ equity 5.1 Balance sheet at December 31, 2007 5.2 Statement of shareholders’ equity 2007 5.3 Acquisitions Appendix 6 New products launched in 2007 Appendix 7 Selected key figures, environmental and social data Appendix 8 Stock exchange announcements for 2007 (excluding insider trading) Appendix 9 Financial calendar 2008 Appendix 10 2008 and long-term sales expectations Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 16 of 27 Group financial statement for 2007
  • 17. Appendix 1: Main items and key figures 1.1 For the fourth quarter 2007 2007 2006 2007 2006 % change % change (DKK million) 4Q 4Q S ales 7,438 6,802 9% 1,844 1,764 5% Gros s profit 3,949 3,655 8% 986 911 8% Gros s margin 53.1% 53.7% 53.5% 51.6% Operating profit 1,481 1,340 11% 332 334 -1% Operating profit margin 19.9% 19.7% 18.0% 18.9% - - Net financials (96) (122) (21) (12) P rofit before tax 1,385 1,218 14% 311 322 -4% C orporation tax (343) (307) 12% (79) (82) -4% Net profit 1,042 911 14% 232 240 -3% Attributable to: S hareholders in the parent company 1,048 909 15% 237 244 -3% - E quity minority interes ts (6) 2 - (5) (4) - - F oreign exchange gain/(los s ), net 5 (50) (4) 12 - - Interes t income/(cos ts ) (78) (26) (22) (10) - - Other financial items (23) (46) 5 (14) Total financ ial inc ome/(c os ts ) (96) (122) - (21) (12) - E arnings per DKK 10 s hare 16.93 14.46 17% 3.85 3.94 -2% Average no. of A/B s hares , outs tanding (million) 61.9 62.9 61.8 61.9 E arnings per DKK 10 s hare 16.47 14.09 17% 3.76 3.84 -2% (diluted) Average no. of A/B s hares , diluted 63.6 64.5 63.4 63.6 (million) F ree c as h flow before ac quis itions 963 1,058 -9% R eturn on inves ted capital (R OIC ), incl. goodwill after tax (R OIC ), incl. goodwill 21.7% 20.2% Net interes t-bearing debt (1,769) (1,455) -22% E quity ratio 41.3% 42.6% R eturn on equity 29.5% 25.4% Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 17 of 27 Group financial statement for 2007
  • 18. 1.2 For the years 2003-2007 F ull year (DKK million) 2007 2006 2005 2004 2003 S ales 7,438 6,802 6,281 5,988 5,775 - E nzymes 6,906 6,320 5,898 5,690 5,514 - Microorganis ms 308 348 308 298 261 - BP I 224 134 75 - - Gros s profit 3,949 3,655 3,345 3,150 2,993 Gros s margin 53.1% 53.7% 53.3% 52.6% 51.8% Operating profit (E B IT) 1,481 1,340 1,206 1,089 998 Operating profit margin 19.9% 19.7% 19.2% 18.2% 17.3% Net financials (96) (122) (56) (33) 32 P rofit before tax 1,385 1,218 1,150 1,056 1,030 C orporation tax (343) (307) (289) (281) (284) Net profit 1,042 911 861 775 746 Minority interes ts 6 (2) (3) (11) (9) Net profit inc luding 1,048 909 858 764 737 minority interes ts F oreign exchange gain/(los s ), net 5 (50) (7) 33 81 Interes t income/ (cos ts ) (78) (26) (23) (35) (42) Other financial items (23) (46) (26) (31) (7) Total financ ial inc ome/(c os ts ) (96) (122) (56) (33) 32 R eturn on inves ted capital 21.7% 20.2% 19.3% 17.4% 15.5% after tax (R OIC ) E arnings per DKK 10 s hare 16.93 14.46 13.10 11.19 10.45 Average no. of A/B s hares , outs tanding (million) 61.9 62.9 65.5 68.3 70.5 E arnings per DKK 10 s hare 16.47 14.09 12.79 10.95 10.39 (diluted) Average no. of A/B s hares , diluted 63.6 64.5 67.1 69.8 70.9 (million) Net interes t-bearing debt 1,769 1,455 877 638 782 E quity ratio 41.3% 42.6% 51.9% 55.8% 54.4% R eturn on equity 29.5% 25.4% 22.2% 19.3% 18.2% Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 18 of 27 Group financial statement for 2007
  • 19. Appendix 2: Distribution of sales 2.1 By industry 2007 2006 % change (DKK million) E nzymes 6,906 6,320 9 - detergent enzymes 2,239 2,040 10 - technical enzymes 2,263 1,977 14 - food enzymes 1,699 1,603 6 - feed enzymes 705 700 1 Mic roorganis ms 308 348 (11) BPI 224 134 67 S ales 7,438 6,802 9 2.2 By geographical area 2007 2006 % change % currency % change in (DKK million) impact local currency E urope, Middle E as t & Africa 3,039 2,855 6 (1) 7 North America 2,412 2,066 17 (9) 26 As ia P acific 1,466 1,401 5 (5) 10 Latin America 521 480 9 (1) 10 S ales 7,438 6,802 9 (5) 14 2.3 Quarterly sales by industry 2007 #R E F ! % change (DKK million) 4Q 3Q 2Q 1Q 4Q 3Q 2Q 1Q 4Q/4Q E nzymes 1,759 1,759 1,661 1,727 1,608 1,658 1,538 1,516 9 - detergent enzymes 539 573 555 572 505 538 492 505 7 - technical enzymes 603 581 537 542 550 505 469 453 10 - food enzymes 428 435 402 434 374 438 404 387 14 - feed enzymes 189 170 167 179 179 177 173 171 6 Mic roorganis ms 62 71 91 84 81 83 90 94 (23) BPI 23 30 51 120 75 15 21 23 (69) S ales 1,844 1,860 1,803 1,931 1,764 1,756 1,649 1,633 5 2.4 Quarterly sales by geographical area 2007 2006 % change (DKK million) 4Q 3Q 2Q 1Q 4Q 3Q 2Q 1Q 4Q/4Q E urope, Middle E as t & Africa 726 782 734 797 733 750 689 683 (1) North America 588 593 592 639 530 524 507 505 11 As ia P acific 386 358 355 367 366 354 340 341 5 Latin America 144 127 122 128 135 128 113 104 7 S ales 1,844 1,860 1,803 1,931 1,764 1,756 1,649 1,633 5 Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 19 of 27 Group financial statement for 2007
  • 20. Appendix 3: Statement of cash flow and financial resources 2006 2007 (DKK million) Net profit 1,042 911 R evers als of non-cas h expens es 1,028 996 C orporation tax paid (186) (120) Interes t received 98 133 Interes t paid (159) (147) C as h flow before c hange in working c apital 1,823 1,773 C hange in working c apital (Increas e)/decreas e in receivables (113) (80) (Increas e)/decreas e in inventories 39 (48) Increas e/(decreas e) in trade payables and other liabilities (35) (111) C as h flow from operating ac tivities 1,714 1,534 Inves tments P urchas e of intangible fixed as s ets (14) (13) S ale of property, plant and equipment 8 29 P urchas e of property, plant and equipment (729) (492) P urchas e of minority s hares (16) 0 C as h flow from inves ting ac tivities before (751) (476) ac quis itions F ree c as h flow before ac quis itions 963 1,058 Acquis ition of activities and companies (716) (477) F ree c as h flow after ac quis itions 247 581 Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 20 of 27 Group financial statement for 2007
  • 21. Appendix 4: Income statement % change 2007 2006 (DKK million) Y/Y S ales 7,438 6,802 9 C os t of goods s old (3,489) (3,147) 11 Gros s profit 3,949 3,655 8 S ales and dis tribution cos ts (921) (844) 9 R es earch and development cos ts (995) (880) 13 Adminis trative cos ts (675) (650) 4 Other operating income, net 123 59 108 Operating profit 1,481 1,340 11 F inancial income 130 134 (3) F inancial cos ts (226) (256) (12) P rofit before tax 1,385 1,218 14 C orporation tax (343) (307) 12 Net profit 1,042 911 14 Attributable to: S hareholders in the parent company 1,048 913 Minority interes ts (6) (2) Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 21 of 27 Group financial statement for 2007
  • 22. Appendix 5: Balance sheet and statement of shareholders’ equity 5.1 Balance sheet at December 31, 2007 Assets 2007 2006 (DKK million) End End Completed IT development projects 24 39 Acquired patents, licenses and know-how 766 497 Goodwill 500 216 IT development projects in progress 31 17 Intangible fixed assets 1,321 769 Land and buildings 1,729 1,723 Production equipment and machinery 1,129 1,012 Other equipment 307 319 Property, plant and equipment under construction 677 499 Property, plant and equipment 3,842 3,553 Deferred tax assets 47 45 Non-current financial assets (non-interest-bearing) 8 12 Total fixed assets 5,218 4,379 Raw materials and consumables 251 201 Goods in progress 317 338 Finished goods 754 787 Inventories 1,322 1,326 Trade receivables 1,344 1,193 Tax receivable 207 248 Other receivables 124 145 Receivables 1,675 1,586 Financial assets (interest-bearing) 116 133 Financial assets (non-interest-bearing) 80 44 Total financial assets 196 177 Cash at bank and in hand 460 497 Total current assets 3,653 3,586 Total assets 8,871 7,965 Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 22 of 27 Group financial statement for 2007
  • 23. Liabilities and shareholders' equity 2007 2006 (DKK million) End End Share capital 650 650 Treasury shares (1,837) (1,449) Other reserves 23 86 Retained earnings 4,821 4,072 Minority interests 10 34 Total shareholders' equity 3,667 3,393 Deferred tax liabilities 939 756 Long-term employee benefits 16 15 Non-current provisions 131 134 Non-current financial liabilities (interest-bearing) 1,545 1,637 Non-current financial liabilities (non-interest-bearing) 158 71 Other non-current liabilities (interest-bearing) 21 21 Total non-current liabilities 2,810 2,634 Financial liabilities (interest-bearing) 779 426 Financial liabilities (non-interest-bearing) 35 33 Provisions 84 20 Trade payables 422 386 Tax payable 49 50 Other current liabilities 1,025 1,023 Total current liabilities 2,394 1,938 Total liabilities 5,204 4,572 Total liabilities and shareholders' equity 8,871 7,965 5.2 Statement of shareholders’ equity 2007 2007 2006 (DKK million) S hareholders ' equity exc l. minority interes ts – beginning of period 3.359 3.761 Net profit 1.048 909 Dividend paid (278) (255) P urchas e of treas ury s hares , net (388) (996) C urrency trans lation of net as s ets , etc. (84) (60) S hareholders ' equity exc l. minority interes ts 3.657 3.359 Minority interes ts – beginning of period 34 33 Net profit (6) 2 Dividend paid (1) (1) C urrency trans lation of net as s ets , etc. (1) (1) C hange in minority interes ts (16) 3 Minority interes ts – end of period 10 34 Total equity – end of period 3.667 3.393 Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 23 of 27 Group financial statement for 2007
  • 24. 5.3 Acquisitions B ioc on P hilom B ios Inc . I alt C arrying F air value on C arrying F air value on C arrying F air value on amount prior date of amount prior date of amount prior date of to acquis ition acquis ition to acquis ition acquis ition to acquis ition acquis ition The as s ets and liabilities aris ing from acquis itions are as follows : Intangible as s ets - 318 1 59 1 377 P roperty, plant and equipment 7 9 37 37 44 46 Inventories 23 29 21 24 44 53 R eceivables and prepayments 40 40 7 7 47 47 C as h and cas h equivalents - - 8 8 8 8 Liabilities (9) (9) (34) (55) (43) (64) Ac quired net as s ets 79 405 108 190 187 595 Goodwill of acquis itions 200 (71) 129 Total purc has e pric e 605 119 724 Les s : C as h and cas h equivalents in acquired companies - 8 8 C as h flow from ac quired c ompanies 605 111 716 The acquired as s ets and goodwill compris e the following: C as h cons ideration 593 116 709 Directs cos ts attributable to the acquis itions 12 3 15 Totan purc has e pric e 605 119 724 F air value of acquired as s ets 405 190 595 Goodwill 200 (71) 129 Biocon On October 1, 2007 Novozymes purchased the activities in the enzyme part of Biocon Limited. The total purchase price was DKK 605 million including discount of future payments for obtaining certain business targets. The fair value figures are to a certain extent based on fair values made by an external assessor, but a few items are estimated in the light of information and subsequent changes can appear if new information appears. Philom Bios Inc. On December 10, 2007 Novozymes purchased the share in Philom Bios Inc. The total purchase price was DKK 119 million. The fair values in Philom Bios Inc. is based on a provisional value because it was not possible to finish the valuation before the preparation of the annual report due to the short time Novozymes has owned the company. Goodwill represents the difference between the value of the acquired companies and the value allocated to the specific net assets. Hence, goodwill represents assets for which a value cannot be measured reliably, including early-stage research projects and expected synergies arising in connection with the fusion of the existing business. The purchased companies enter into the Income statement for 2007 with sales of DKK 20 million and a minor loss. It has not been possible to enlighten the combined sales and result from the beginning of the year as their accounting year and accounting policies have not been following the policies of the Novozymes Group together with the fact that an individual report for Biocon’s enzyme activitiy has not been prepared as they are entered into an integrated part of the Biocon group. Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 24 of 27 Group financial statement for 2007
  • 25. Appendix 6: New products launched in 2007 ® Mannaway , an enzyme for the detergent indus try des igned to remove mannan-containing 1Q 2007 s tains ® Vis coferm , an enzyme for the alcohol indus try reducing vis cos ity as well as water and 1Q 2007 energy cons umption in the production proces s ® 1Q 2007 HyaC are , an optimized hyaluronic acid for eyecare in the medical device market ® S tainzyme P lus , a detergent enzyme with improved was hing characteris tics at low 2Q 2007 temperatures ® Ultraflo Max, an enzyme for the brewing indus try which allows a long and cons is tent 2Q 2007 filtration proces s and therefore an optimized production proces s ® S aczyme , a cos t-effective enzyme for the alcohol indus try us ed to convert raw materials 2Q 2007 into fermentable s ugars ® R onozyme NP , an improved enzyme for the feed indus try us ed to releas e naturally 2Q 2007 occurring phos phate in feed for pigs and poultry ® S pirizyme Ultra, an enzyme us ed in the conventional convers ion of corn to bioethanol to 2Q 2007 increas e yields ® Acrylaway , an enzyme for the food indus try us ed to reduce the level of acrylamide in food 3Q 2007 products 4Q 2007 S ucrozyme, an enzyme for the food indus try us ed to manufacture s weeteners Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 25 of 27 Group financial statement for 2007
  • 26. Appendix 7: Selected key figures, environmental and social data 2007 2006 % change Water cons umption (related to goods s old), 1,000 m³ 5.439 4.871 12 E nergy cons umption, 1,000 GJ 3.745 3.307 13 S ignificant s pills - - F atalities - - F requency of occupational accidents pr. million working hours 4,8 3,7 E mployees at December 31, 2007 4.933 4.544 9 R ate of employee turnover 9,0% 8,0% R ate of abs ence 2,2% 2,3% Appendix 8: Stock exchange announcements for 2007 E xcluding ins iders ' trading J anuary 25, 2007 Group financial s tatement for 2006 F ebruary 19, 2007 Novozymes awarded damage payment for patent infringement March 9, 2007 Annual Meeting of S hareholders 2007 April 3, 2007 C hange in revenue reporting April 17, 2007 Novozymes terminates patent infringement s uit April 25, 2007 Group financial s tatement, firs t quarter of 2007 J uly 18, 2007 Novozymes to acquire the enzyme bus ines s of Biocon, India Augus t 9, 2007 Group financial s tatement for firs t half of 2007 Augus t 28, 2007 C hanges in Novozymes ' E xecutive Managment as of October 1, 2007 October 1, 2007 Acquis ition of enzyme activities from Biocon completed October 25, 2007 Group financial s tatement for the firs t nine months of 2007 October 31, 2007 Novozymes to acquire P hilom Bios Inc., C anada December 10, 2007 P hilom Bios acquis ition completed Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 26 of 27 Group financial statement for 2007
  • 27. Appendix 9: Financial calendar 2008 March 5, 2008 Annual Meeting of S hareholders April 24, 2008 Group financial s tatement for firs t quarter of 2008 Augus t 14, 2008 Group financial s tatement for firs t half of 2008 October 31, 2008 Group financial s tatement for firs t nine months of 2008 Appendix 10: 2008 and long-term sales expectations E xpec ted growth R ealized growth C AGR (LC Y) Long-term (LC Y) 2008 (DKK) 2008 (LC Y) F Y07 (DKK) F Y07 (LC Y) (2003-07) Detergent enzymes 3-5% ~4% ~5% 10% 12% 3% Technical enzymes 15-18% 20-25% 25-30% 14% 22% 16% F ood enzymes ~10% 2-7% 5-10% 6% 9% 6% F eed enzymes 5-10% ~0% ~0% 1% 5% 6% Microorganis ms 10% 10-20% 20-30% -11% -5% 9% Biopharmaceutical 10-15% ~(20)% ~(15)% 67% 64% NA ingredients Total s ales 8-10% 8-11% 11-14% 9% 14% 8% Novozymes A/S – Stock exchange announcement no. 1, 2008 Page 27 of 27 Group financial statement for 2007