NovioTech BV is a private company founded in 2011 that works to commercialize new technologies from Radboud University. It has several scientific advisors and shareholders. NovioTech collaborates closely with Radboud University to translate research into products. This presentation provides an overview of NovioTech's portfolio and approach, including the NovioSense glucose sensor, NovioHelix thermogel polymer, and NanoWipe. For NanoWipe, the presentation discusses the nanotechnology market opportunity, competition from other wipes, hurdles to developing a market-ready product, and potential customers for field testing and validation. The overall goal is to bridge the gap between scientific discovery and commercialization.
iNovacia is an established quality provider of lead generation services including high-throughput screening and fragmen based screening. This is supported by a compound collection (ca 300,000 cmpds) and screening libraries of highest international standards with focus on diversity and novelty.
Keynote Health Tech Event Eindhoven - Open Innovation Health Tech Opportuntie...BenHeublKeynotes
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The 10 most trusted vaccine solution providers, 2020Merry D'souza
In this edition, ‘The 10 Most Trusted Vaccine Solution Providers, 2020’ CIO Look has shortlisted various healthcare organizations which are playing an important role towards the global healthcare system.
iNovacia is an established quality provider of lead generation services including high-throughput screening and fragmen based screening. This is supported by a compound collection (ca 300,000 cmpds) and screening libraries of highest international standards with focus on diversity and novelty.
Keynote Health Tech Event Eindhoven - Open Innovation Health Tech Opportuntie...BenHeublKeynotes
Keynote Health Tech Event Eindhoven Keynote Ben Heubl - Open Innovation Health Tech Opportunities in Northern Europe (as part of a conference, exhibition and Start-Up Plaza on topics like Diagnostics, Telemedicine, Treatments, Regeneration and Augmentation).
The 10 most trusted vaccine solution providers, 2020Merry D'souza
In this edition, ‘The 10 Most Trusted Vaccine Solution Providers, 2020’ CIO Look has shortlisted various healthcare organizations which are playing an important role towards the global healthcare system.
MOEBIO is a disruptive talent development initiative of Biocat where life sciences, health, business and technology meet in a new level to accelerate entrepreneurship in healthcare. It is an integral, new educational program focused on solving society's great problems and challenges by creating the future generation of innovators in healthcare.
Design Health Barcelona is the flagship of MOEBIO. A Higher Education Program inspired in the prestigious Stanford University's Biodesign Fellowship.
Radboudumc as business partner. Presentation by Dirkjan Masman (Director Valorisation) during 'From Molecule to Business' event by SMB Life Sciences and Health Valley at NovioTechCampus, Nijmegen, The Netherlands on September 29, 2016.
The IMI EHDEN project: large-scale analysis of observation data in Europe - C...Maxim Moinat
The European Health Data & Evidence Network (EHDEN) project, funded via the Innovative Medicines Initiative (IMI), is the largest of its kind in Europe working in the domain of RWD/RWE. It is a public private partnership consortium of 22 partners, from 2018 to 2024, led by Erasmus Medical Center (EMC) and Janssen, working to create an open science community symbiotic with the Observational Health Data Science and Informatics (OHDSI) global framework to facilitate observational/RWD-based research at scale and acceleration, without impinging on quality. At its core is the standardisation of RWD via use of the Observational Medical Outcomes Partnership (OMOP) common data model (CDM), standardised analytics and a sustainable research community for the coming decades. Potentially, between EHDEN and OHDSI there are several use cases developed on the boundaries between clinical trials and observational data, and we look forward discussing these with the CDISC community.
Tomorrow’s Lab Today: Focus areas for medical biology and diagnostic testing ...Serene Touma
Healthcare will require a new approach and tools to support new patient expectations in 2020. A patient-centric approach to healthcare will be more relevant than ever.
Covid-19 has uncovered new challenges and weaknesses in care that are dependent on a centralized set-up.
What is becoming more and more clear is that diagnostic labs need to evolve and up their game to stay relevant. This will continue to bring value to patients throughout the healthcare journey.
A key focus in 2021 will be taking a look at building and maintaining better relationships between private and public players in patient care.
Pharma IQ brings you Clinical Trial Supply Europe Conference Profit. Successfully cutting costs and overages whilst increasing the flexibility and reactivity of your clinical supply network to support global clinical trials.
POINT-of-IMPACT testing. A European perspective - Bert NiestersWAidid
At SoGat meeting 2019 Bert Niesters - Professor in Molecular Diagnostic in Clinical Virology, Medical Molecular Microbiologist at University Medical Center Groningen, Department of Medical Microbiology, Division of Clinical Viroloy, The Netherlands - has talked about the developing trends in molecular diagnostics and the impact on the Laboratory.
To learn more, please visit www.waidid.org!
MOEBIO is a disruptive talent development initiative of Biocat where life sciences, health, business and technology meet in a new level to accelerate entrepreneurship in healthcare. It is an integral, new educational program focused on solving society's great problems and challenges by creating the future generation of innovators in healthcare.
Design Health Barcelona is the flagship of MOEBIO. A Higher Education Program inspired in the prestigious Stanford University's Biodesign Fellowship.
Radboudumc as business partner. Presentation by Dirkjan Masman (Director Valorisation) during 'From Molecule to Business' event by SMB Life Sciences and Health Valley at NovioTechCampus, Nijmegen, The Netherlands on September 29, 2016.
The IMI EHDEN project: large-scale analysis of observation data in Europe - C...Maxim Moinat
The European Health Data & Evidence Network (EHDEN) project, funded via the Innovative Medicines Initiative (IMI), is the largest of its kind in Europe working in the domain of RWD/RWE. It is a public private partnership consortium of 22 partners, from 2018 to 2024, led by Erasmus Medical Center (EMC) and Janssen, working to create an open science community symbiotic with the Observational Health Data Science and Informatics (OHDSI) global framework to facilitate observational/RWD-based research at scale and acceleration, without impinging on quality. At its core is the standardisation of RWD via use of the Observational Medical Outcomes Partnership (OMOP) common data model (CDM), standardised analytics and a sustainable research community for the coming decades. Potentially, between EHDEN and OHDSI there are several use cases developed on the boundaries between clinical trials and observational data, and we look forward discussing these with the CDISC community.
Tomorrow’s Lab Today: Focus areas for medical biology and diagnostic testing ...Serene Touma
Healthcare will require a new approach and tools to support new patient expectations in 2020. A patient-centric approach to healthcare will be more relevant than ever.
Covid-19 has uncovered new challenges and weaknesses in care that are dependent on a centralized set-up.
What is becoming more and more clear is that diagnostic labs need to evolve and up their game to stay relevant. This will continue to bring value to patients throughout the healthcare journey.
A key focus in 2021 will be taking a look at building and maintaining better relationships between private and public players in patient care.
Pharma IQ brings you Clinical Trial Supply Europe Conference Profit. Successfully cutting costs and overages whilst increasing the flexibility and reactivity of your clinical supply network to support global clinical trials.
POINT-of-IMPACT testing. A European perspective - Bert NiestersWAidid
At SoGat meeting 2019 Bert Niesters - Professor in Molecular Diagnostic in Clinical Virology, Medical Molecular Microbiologist at University Medical Center Groningen, Department of Medical Microbiology, Division of Clinical Viroloy, The Netherlands - has talked about the developing trends in molecular diagnostics and the impact on the Laboratory.
To learn more, please visit www.waidid.org!
180703 start updelta on tour slides smb meetingSMBBV
Publication of presentation by Katja Berkhout from Start Up Delta on Tour (Sharing experiences and challenges) as presented during the SMB meeting at Novio Tech Campus in Nijmegen on July 3, 2018.
Publication of presentation by Jorg Rijkschroeff from Sit&Heat (Sharing experiences and challenges) as presented during the SMB meeting at Novio Tech Campus in Nijmegen on July 3, 2018.
Publication of presentation by Klaus Werner from PinkRF (Sharing experiences and challenges) as presented during the SMB meeting at Novio Tech Campus in Nijmegen on July 3, 2018.
Presentation on VR sound project by Radboud University Bachelor students (Innovation Science course) as presented duing the SMB meeting on February 22, 2018 at Novio Tech Campus in Nijmegen.
Presentation on LowKey urine testing project by Radboud University Bachelor students (Innovation Science course) as presented duing the SMB meeting on February 22, 2018 at Novio Tech Campus in Nijmegen.
Presentation on Hemispatial Neglect project by Radboud University Bachelor students (Innovation Science course) as presented duing the SMB meeting on February 22, 2018 at Novio Tech Campus in Nijmegen.
180222 ru student presentation 1 n ox measurementSMBBV
Presentation on NO2-sense project by Radboud University Bachelor students (Innovation Science course) as presented duing the SMB meeting on February 22, 2018 at Novio Tech Campus in Nijmegen.
1. 21‐2‐2013
noviotech BV
bringing technologies to the market
Titel presentatie:
van Glucose Sensor tot Hydrogel
31 januari 2013
www.noviotech.com
Molenveldlaan 43
6523 RJ, Nijmegen
The Netherlands
Tel. +31 24 71 14 015
1
2. 21‐2‐2013
Organisatie
Private onderneming, onafhankelijk
Opgericht in 2011 door Hanssen/Tweehuysen
Aandeelhouders:
Tweehuysen Holding BV
Hanssen Investment and Consultancy BV
Prof. dr. Ir. Jan C.M. van Hest (RU, Bio-organische chemie)
Prof. dr. Alan E. Rowan (RU, Moleculaire materialen)
Wetenschappelijk adviseurs:
Prof. dr. Jan van Hest,
Prof. dr. Alan Rowan en
Prof. dr. Roeland Nolte (oud directeur IMM, lid KNAW, leerstoel
macromoleculaire chemie, polymeer- en nanotechnologie)
Samenwerking met de Radboud Universiteit:
2
3. 21‐2‐2013
Bron: website Radboud
Universiteit
“Samen met Noviotech,
commercieel partner van de
Radboud Universiteit en het
Radboud Universiteit Medisch
Centrum, worden
verschillende richtingen
onderzocht.”
Bron: NRC van
25 januari 2013,
wetenschapsbijlage
3
4. 21‐2‐2013
Bron: de Gelderlander van 26
januari 2013:
“Samen met het bedrijf
NovioTech kijken de
scheikundigen hoe de stof in de
medische wereld kan worden
toegepast.”
Medewerkers NovioTech
BV/NovioSense BV
MSc Margo Groeneveld
MSc Hans Hanssen
MSc Jan Lauko
Dr. Hera Lichtenbeld
Dr. Marco Thio
Ir. R. Tweehuysen
MSc. Jeroen van der Velden
Dr. Chris Wilson
4
5. 21‐2‐2013
Doel van de presentaties
Valorisatie van kennis:
Innovation gap, ‘Valley of Death’
valorisatie van kennis, kan dat beter ??
Daartoe aan de hand van concrete
voorbeelden:
Portfolio en werkwijze NovioTech BV a.d.h. van :
NovioSense glucose sensor
NovioHelix thermogel
Nanowipe
5
6. 21‐2‐2013
NanoWipe
Contacts with Potential End Users (DSM Resolve) and
Instrument Manufacturers (NanoSight UK)
6
7. 21‐2‐2013
Impressie van NovioTech als
Pijplijn, spin-off en nieuwe ontwikkelingen
Laagdrempelig voor onderzoekers met interesse in het
opzetten van een bedrijf, opdoen van ervaring
Breed netwerk met bedrijven in LS en maakindustrie
Open innovatie!
7
9. Telemedicine
Telemedicine is not new:
Native Americans use smoke signals to warn of illness
People in Remote Areas use two-way radio to
communicate with doctors
Medicine at a Distance:
Consultation via e-mail, telephone or video conference
Real-time single point data and trend analysis
Dynamic and responsive healthcare regimen changes
14. Early disease detection and early disease management
Real-Time management of chronic conditions
Reduced Burden on Healthcare and Increased Quality of Life
16. Continuous Glucose Monitors
Finger Prick Glucose – Single Snapshot in Time
Continuous Montior – Follows Glucose Trends in Time
Alerts for oncoming highs and lows
Alerts during resting hours
Correlate effects of diet and exercise on glucose levels
CGM results in tighter glucose control, high patient
compliance and reduction in hospital visits
17. Market
Bottom line CGM use reduces costs to the insurer!
CGM Statistics Collected in the Netherlands1
Hospital admision reduced by upto 80%
Severe Hypoglycemia reduced by 85%
1. British Journal of Diabetes and Vascular Disease 2011, 11, 3, 145-149
26. About me
HLO RU
1994
now
Technician PhD NovioTech
biochemistry biology
Val
27. Mt. NovioHelix
the summit
deals
customers
team
market study
IP
ideas
28. thermoreversible
customizable mimics ECM
NovioHelix
biocompatible nanosized pores
4°C 37°C
optically
>99.95% water
transparent
“Take one kilogram of polyisocyanide polymer. Sprinkle liberally across an Olympic swimming
pool. Warm gently. Within minutes, your jelly is ready. Serves 25 million.” (A. Rowan, Radboud)
“I can’t think of another synthetic material that shows this specific behavior,” (D. Weitz, Harvard)
“the first semi‐flexible synthetic polymers to have tunable properties,” ( M. Gardel, Univ. of Chicago)
29. NovioHelix: ideas
Drug
Cell Culture Cosmetics Household Wound care
Delivery
and many many more...
30. NovioHelix: market
NovioHelix: IP
Radboud University
Drug
Cell Culture Cosmetics Household Wound care
Delivery excl. worldwide license
>$6B >$170B >$20B >$10B
NovioTech
market size
competitors
keyplayers
prospects
31. Mt. NovioHelix
deals
customers
team
market study
IP
ideas
39. Nanotechnology
What is it and why it matters...
Arranging
Atoms
Now:
Legoblocks
handled with
boxing gloves
Nanotech:
Take off boxing
gloves
- Confidential -
40. Market Segments & GR
All new products – didn’t exist 10 yrs
ago Fast growing market
Powders best penetrated now, other markets still need growth and follow later
- Confidential -
41. “Nano” Risk Management
New technology challenge is in the Potential Risks
Nanomaterial properties differ from bulk counterpart (potential
hazard)
Extreme small properties allow for easy absorption in humans
(exposure)
x =
Hazard Exposure Risk
- Confidential -
42. Focus on exposure: new tools required
detect
?
NanoWipe
x =
Hazard Exposure
- Confidential -
43. Nanowipe
Tunable thermosensitive hydrogel
Nanowipe prototype
developed & proof of
principle studies done
industry standard E2834-12 (ASTM standard for
nanoparticle analysis – similar to ISO standards)
- Confidential -
44. NanoWipe - competition
Competition comes from aerosol instruments & other wipes
<100% 100% (±10)
Sample Mean Variance
Recovery Recovery
Ghostwipe
(digest)
Ghostwipe
(non‐digest)
Kimtech
Precision Wipe
Lab Paper
UltraWipe ‐ ‐
NanoWipe ±
Competitive in house testing shows no comparable wipe on the market
Most wipes generate NPs rather than collect them
Recovery NPs from wipes is destructive for NPs in other wipes
- Confidential -
45. Hurdles to a market ready NanoWipe
What Potential hurdles
Tissue, holder, foil? Use of wipe, idiot
proof?
Packaging – foil, paper pouch, blisterpack None expected
Market ready product None expected
Field testing Number test clients
Product validation Batch consistency
Supply chain Delivery
- Confidential -