This document describes remote biomedical monitoring techniques using light. It discusses using light to "hear" sounds from a distance by analyzing reflected light patterns. The techniques allow continuous remote monitoring of various vital signs like breathing, heart rate, blood pressure, glucose levels, and more. Clinical trials were conducted to test monitoring breathing, heartbeats, blood pressure, and glucose levels. The methods could allow continuous remote monitoring without contact for situations like patients under quarantine.
This document outlines a project on photonic remote and continuous biomedical diagnostics. It describes using laser light projection and imaging to remotely "hear" human speech, heartbeats, and other sounds from a distance without physical contact. The system can work through glass, in noisy environments, and can separate multiple sound sources. It then demonstrates applications for remotely monitoring breathing, heart rate, blood glucose and other biometrics, as well as detecting conditions like malaria and alcohol levels.
This document outlines the by-laws of CSA Makati 91, Inc. It discusses the organization of meetings of members, including annual meetings, monthly/special meetings, notices of meetings, quorums, and voting procedures. It also outlines the structure of the Board of Trustees, including their powers and duties, qualifications for trustees, vacancies, and terms. Finally, it discusses the election and roles of officers, including the Executive Director, Deputy Executive Director, Secretary, Treasurer, and Auditor. Committees and functions are also established for a Homecoming Committee and Outreach Committee.
JMARS Lending Investors Inc. was established to help people fulfill their needs and dreams by providing affordable loans. Its vision is to be a reliable source of financial assistance with reasonable interest rates. The company aims to open more branches across the Philippines to conveniently serve more customers. Its goals are to achieve 20-30% average profit over three years, ensure good customer service, and expand to new locations.
This document establishes the articles of incorporation for CSA Makati 91, Inc. The corporation is formed by alumni of Colegio San Agustin Makati High School class of 1991 to raise funds for class reunions and community outreach. It outlines the corporation's name, purpose, offices, term, and initial trustees and contributions.
KontrolTM is a web-based system that allows businesses to manage shared equipment across locations. It provides equipment tracking, automatic replenishment, and reporting capabilities. KontrolTM ensures the right equipment is in the right place at the right time for any supply chain. It integrates with ERP systems and can track equipment by serial number with geo-location services. KontrolTM aims to improve equipment efficiency and save companies money.
This document summarizes a G20 Young Entrepreneurs' Alliance summit in Istanbul, Turkey. It discusses how entrepreneurship has transformed from a narrow commercial field into one with significant cultural impact and the potential to benefit all of humanity. Young firms on average create over 1.5 million new jobs each year. National boundaries are diminishing as social and informal networks allow global teams to quickly form, succeed, or reorganize. The document promotes transforming dreams into businesses with positive economic, environmental and social impacts, and frames "Blue Growth" and entrepreneurship as ways to address poverty and activate human potential.
Профессор Слоуновской школы менеджмента при MIT Нил Хартман рассказал в Digital October, какие ошибки случаются, если вы строите компанию с представителями различных культур или пытаетесь перенести глобальные практики бизнеса на чужеродную почву, и как их избежать.
http://digitaloctober.ru/ru/events/knowledge_stream_1000_i_1_kultura_predprinimatelstva
CCH Integrator is a cloud-based software platform that allows multinational corporations to standardize, streamline and manage their global tax processes. It facilitates automated compliance with country-by-country reporting requirements through centralized data collection and generation of reports. It also includes a transfer pricing document builder to automate the creation of documentation like a master file on a template basis across different languages.
This document outlines a project on photonic remote and continuous biomedical diagnostics. It describes using laser light projection and imaging to remotely "hear" human speech, heartbeats, and other sounds from a distance without physical contact. The system can work through glass, in noisy environments, and can separate multiple sound sources. It then demonstrates applications for remotely monitoring breathing, heart rate, blood glucose and other biometrics, as well as detecting conditions like malaria and alcohol levels.
This document outlines the by-laws of CSA Makati 91, Inc. It discusses the organization of meetings of members, including annual meetings, monthly/special meetings, notices of meetings, quorums, and voting procedures. It also outlines the structure of the Board of Trustees, including their powers and duties, qualifications for trustees, vacancies, and terms. Finally, it discusses the election and roles of officers, including the Executive Director, Deputy Executive Director, Secretary, Treasurer, and Auditor. Committees and functions are also established for a Homecoming Committee and Outreach Committee.
JMARS Lending Investors Inc. was established to help people fulfill their needs and dreams by providing affordable loans. Its vision is to be a reliable source of financial assistance with reasonable interest rates. The company aims to open more branches across the Philippines to conveniently serve more customers. Its goals are to achieve 20-30% average profit over three years, ensure good customer service, and expand to new locations.
This document establishes the articles of incorporation for CSA Makati 91, Inc. The corporation is formed by alumni of Colegio San Agustin Makati High School class of 1991 to raise funds for class reunions and community outreach. It outlines the corporation's name, purpose, offices, term, and initial trustees and contributions.
KontrolTM is a web-based system that allows businesses to manage shared equipment across locations. It provides equipment tracking, automatic replenishment, and reporting capabilities. KontrolTM ensures the right equipment is in the right place at the right time for any supply chain. It integrates with ERP systems and can track equipment by serial number with geo-location services. KontrolTM aims to improve equipment efficiency and save companies money.
This document summarizes a G20 Young Entrepreneurs' Alliance summit in Istanbul, Turkey. It discusses how entrepreneurship has transformed from a narrow commercial field into one with significant cultural impact and the potential to benefit all of humanity. Young firms on average create over 1.5 million new jobs each year. National boundaries are diminishing as social and informal networks allow global teams to quickly form, succeed, or reorganize. The document promotes transforming dreams into businesses with positive economic, environmental and social impacts, and frames "Blue Growth" and entrepreneurship as ways to address poverty and activate human potential.
Профессор Слоуновской школы менеджмента при MIT Нил Хартман рассказал в Digital October, какие ошибки случаются, если вы строите компанию с представителями различных культур или пытаетесь перенести глобальные практики бизнеса на чужеродную почву, и как их избежать.
http://digitaloctober.ru/ru/events/knowledge_stream_1000_i_1_kultura_predprinimatelstva
CCH Integrator is a cloud-based software platform that allows multinational corporations to standardize, streamline and manage their global tax processes. It facilitates automated compliance with country-by-country reporting requirements through centralized data collection and generation of reports. It also includes a transfer pricing document builder to automate the creation of documentation like a master file on a template basis across different languages.
O documento classifica a paisagem em natural e cultural e fornece exemplos de cada categoria, como árvores, montanhas e rios para natural, e prédios, cidades e museus para cultural. Ele também lista tipos de vegetação encontrados em diferentes regiões do Brasil.
Las ciencias de la computación estudian las bases teóricas de la información y la computación, así como su aplicación en sistemas computacionales. La historia de esta disciplina se remonta a antes de la invención de la computadora digital moderna, cuando el término "computador" se refería a una persona que realizaba cálculos. Los primeros investigadores en esta área estudiaban la compatibilidad de los problemas que podían ser resueltos siguiendo instrucciones con lápiz y papel.
Este documento proporciona instrucciones para colaborar en un grupo de trabajo para crear y configurar hipervínculos, publicar una presentación en Internet usando Google Slides, y revisar presentaciones. Explica cómo insertar hipervínculos, inscribirse como miembro en Google Slides, cargar archivos y publicar diapositivas en un blog.
Este documento discute o papel do Conselho Tutelar dentro do ambiente escolar. Ele apresenta o que já se sabe sobre o assunto, como mediar conflitos e proteger crianças. Também levanta perguntas como quem defende os "bons alunos" quando alunos problemáticos são inseridos e até que ponto o Conselho Tutelar pode interferir na escola.
O documento apresenta um problema de programação linear para maximizar o lucro total de uma indústria produzindo dois produtos utilizando três materiais sob restrições de estoque. Ele fornece um roteiro de 10 passos para resolver o problema algebraicamente e graficamente, encontrando que a solução ótima é produzir 4 unidades do Produto A e 2 unidades do Produto B.
Procedimentos armazenados permitem armazenar comandos SQL no servidor para serem executados posteriormente de forma concisa. Eles podem receber parâmetros de entrada e saída, definir variáveis e lógica condicional para manipular dados de forma padronizada em diferentes aplicações. Sua sintaxe inclui nome, parâmetros, corpo com comandos SQL e pode retornar valores.
Este documento presenta un mapa conceptual de los elementos clave de la planificación, organización, dirección y control de una empresa. La planificación incluye la definición de objetivos, estrategias, políticas, procedimientos y presupuestos. La organización se refiere a la distribución de líneas de autoridad y trabajo. La dirección implica influir en las personas para lograr las metas. El control mide y corrige el desempeño a través de mecanismos preliminares, concurrentes y de retroalimentación.
Las ciencias de la computación estudian las bases teóricas de la información y la computación, así como su aplicación en sistemas computacionales. La historia de esta disciplina se remonta a antes de la invención del computador digital moderno, cuando el término "computador" se refería a una persona que realizaba cálculos. Los primeros investigadores en esta área estudiaban la compatibilidad de los problemas que podían ser resueltos siguiendo instrucciones con lápiz y papel.
Slideshare permite a los usuarios subir presentaciones PowerPoint y OpenOffice en formato Flash para que otros puedan verlas en línea de forma gratuita. Los usuarios pueden compartir presentaciones de hasta 20 Mb sin transiciones entre diapositivas. Slideshare ofrece una forma sencilla de compartir presentaciones en la web.
Luce fabri,o anarquismo e as mulheres (margareth rago)Elaine Campos
O documento discute a biografia da militante anarquista italiana Luce Fabbri e sua relação com o feminismo. Apesar de não se considerar uma feminista, Luce trouxe uma perspectiva feminina ao anarquismo através de sua experiência de vida e trabalho. Ela acreditava que a emancipação das mulheres fazia parte da questão social mais ampla. O documento também descreve o contexto do Uruguai na época em que Luce chegou, com direitos como o divórcio, mas também costumes que limitavam as mulheres.
Este documento describe cómo utilizar Microsoft Office Picture Manager para editar imágenes. Primero se captura una imagen presionando PrtScr/SysRq y se pega en Picture Manager. Luego, se hace clic en "Editar" en el panel de tareas para acceder a opciones como ajustar el brillo, color, recortar, girar, eliminar ojos rojos, cambiar el tamaño y comprimir imágenes. El documento proporciona instrucciones en 3 pasos para utilizar las funciones básicas de edición de imágenes en Picture Manager.
Este documento presenta un resumen de un proyecto de video performance realizado por cuatro estudiantes con el objetivo de intervenir en la cotidianidad de las personas y romper con la rutina mediante la representación de la infancia y la libertad, la espontaneidad y la alegría asociadas a ella. El proyecto buscaba generar una actitud diferente en busca de la felicidad a través de la simplicidad. Sin embargo, observaron que las personas rechazaron salir de sus esquemas y prejuicios sociales debido a su inmersión en la
BioCloth es una empresa que busca comercializar ropa biodegradable hecha de una fibra llamada Ingeo obtenida del maíz. La empresa planea ofrecer prendas deportivas y de vestir urbanas de doble faz a precios accesibles para proteger el medio ambiente y reducir emisiones de CO2. Su visión es expandirse a nivel nacional en 2 años y llegar a Latinoamérica en 5 años.
O texto discute como as tentações surgem dos próprios desejos das pessoas e não de Deus, levando ao pecado e à morte. Primeiro vem o desejo mal, depois a dúvida e engano, resultando em desobediência.
Un polinomio es la suma de varios monomios. Se compone de un número finito de variables y sólo utiliza las operaciones de adición, sustracción, multiplicación y potenciación con exponentes naturales. El grado de un polinomio es la mayor potencia de los monomios que lo componen. La resolución de ecuaciones algebraicas mediante polinomios se remonta a casi 4000 años atrás, aunque la notación actual data del siglo XV. Todo polinomio tiene al menos una raíz compleja, según el teorema fundamental del álgebra.
El documento presenta información sobre tres redes sociales: Google Buzz, Twitter y Facebook. Describe sus conceptos, usos, características, ventajas y desventajas. El objetivo es comparar los servicios que ofrecen estas plataformas y conocer cómo se utilizan. Google Buzz permite conversar y compartir recursos en línea de forma pública o privada. Twitter es una aplicación web gratuita de microblogging que combina blogs, redes sociales y mensajería instantánea. Facebook conecta amigos en todo el mundo a través de perfiles, muros, mens
La orografía se refiere a las características del relieve de una región, como sus montañas y colinas. Afecta el clima local de varias maneras: las montañas desvían los vientos ascendentes, lo que causa mayor nubosidad y precipitación en las laderas de barlovento, mientras que el lado de sotavento suele ser más seco. La orografía también influye en la formación de nubes como las lenticulares. El estudio de la orografía es útil para comprender mejor el territorio y planificar infraestructura.
Este documento explica cómo resolver ecuaciones algebraicas mediante el despeje de incógnitas. Define una ecuación como una igualdad matemática entre dos expresiones que contienen valores conocidos y desconocidos. Explica que resolver una ecuación es encontrar el valor de la incógnita que satisface la igualdad. A continuación, muestra ejemplos de cómo despejar la x, m, y otras incógnitas en diferentes ecuaciones mediante la adición y sustracción de términos en ambos lados de la igualdad.
1) A Terra tem forma de elipsóide com semieixos equatorial de 6378137 km e polar de 6356752 km. Isso resulta em uma excentricidade de 0,0818.
2) Um estudante representou a órbita elíptica da Terra em torno do Sol com barbante de 2m para o eixo maior, resultando em uma distância focal de 34 cm.
3) Usando a terceira lei de Kepler, calculou-se que Mercúrio está a aproximadamente 57,9 milhões de km do Sol.
29 ноября сооснователь некоммерческого научно-образовательного проекта для детей, имеющего уже сотни «клонов» в одной лишь Польше, показала в центре Digital October, какой интересной может быть система дополнительного школьного образования, и рассказала, как «Университет детей» в Москву пришел.
http://digitaloctober.ru/ru/events/knowledge_stream_umno_ne_po_detski
O documento classifica a paisagem em natural e cultural e fornece exemplos de cada categoria, como árvores, montanhas e rios para natural, e prédios, cidades e museus para cultural. Ele também lista tipos de vegetação encontrados em diferentes regiões do Brasil.
Las ciencias de la computación estudian las bases teóricas de la información y la computación, así como su aplicación en sistemas computacionales. La historia de esta disciplina se remonta a antes de la invención de la computadora digital moderna, cuando el término "computador" se refería a una persona que realizaba cálculos. Los primeros investigadores en esta área estudiaban la compatibilidad de los problemas que podían ser resueltos siguiendo instrucciones con lápiz y papel.
Este documento proporciona instrucciones para colaborar en un grupo de trabajo para crear y configurar hipervínculos, publicar una presentación en Internet usando Google Slides, y revisar presentaciones. Explica cómo insertar hipervínculos, inscribirse como miembro en Google Slides, cargar archivos y publicar diapositivas en un blog.
Este documento discute o papel do Conselho Tutelar dentro do ambiente escolar. Ele apresenta o que já se sabe sobre o assunto, como mediar conflitos e proteger crianças. Também levanta perguntas como quem defende os "bons alunos" quando alunos problemáticos são inseridos e até que ponto o Conselho Tutelar pode interferir na escola.
O documento apresenta um problema de programação linear para maximizar o lucro total de uma indústria produzindo dois produtos utilizando três materiais sob restrições de estoque. Ele fornece um roteiro de 10 passos para resolver o problema algebraicamente e graficamente, encontrando que a solução ótima é produzir 4 unidades do Produto A e 2 unidades do Produto B.
Procedimentos armazenados permitem armazenar comandos SQL no servidor para serem executados posteriormente de forma concisa. Eles podem receber parâmetros de entrada e saída, definir variáveis e lógica condicional para manipular dados de forma padronizada em diferentes aplicações. Sua sintaxe inclui nome, parâmetros, corpo com comandos SQL e pode retornar valores.
Este documento presenta un mapa conceptual de los elementos clave de la planificación, organización, dirección y control de una empresa. La planificación incluye la definición de objetivos, estrategias, políticas, procedimientos y presupuestos. La organización se refiere a la distribución de líneas de autoridad y trabajo. La dirección implica influir en las personas para lograr las metas. El control mide y corrige el desempeño a través de mecanismos preliminares, concurrentes y de retroalimentación.
Las ciencias de la computación estudian las bases teóricas de la información y la computación, así como su aplicación en sistemas computacionales. La historia de esta disciplina se remonta a antes de la invención del computador digital moderno, cuando el término "computador" se refería a una persona que realizaba cálculos. Los primeros investigadores en esta área estudiaban la compatibilidad de los problemas que podían ser resueltos siguiendo instrucciones con lápiz y papel.
Slideshare permite a los usuarios subir presentaciones PowerPoint y OpenOffice en formato Flash para que otros puedan verlas en línea de forma gratuita. Los usuarios pueden compartir presentaciones de hasta 20 Mb sin transiciones entre diapositivas. Slideshare ofrece una forma sencilla de compartir presentaciones en la web.
Luce fabri,o anarquismo e as mulheres (margareth rago)Elaine Campos
O documento discute a biografia da militante anarquista italiana Luce Fabbri e sua relação com o feminismo. Apesar de não se considerar uma feminista, Luce trouxe uma perspectiva feminina ao anarquismo através de sua experiência de vida e trabalho. Ela acreditava que a emancipação das mulheres fazia parte da questão social mais ampla. O documento também descreve o contexto do Uruguai na época em que Luce chegou, com direitos como o divórcio, mas também costumes que limitavam as mulheres.
Este documento describe cómo utilizar Microsoft Office Picture Manager para editar imágenes. Primero se captura una imagen presionando PrtScr/SysRq y se pega en Picture Manager. Luego, se hace clic en "Editar" en el panel de tareas para acceder a opciones como ajustar el brillo, color, recortar, girar, eliminar ojos rojos, cambiar el tamaño y comprimir imágenes. El documento proporciona instrucciones en 3 pasos para utilizar las funciones básicas de edición de imágenes en Picture Manager.
Este documento presenta un resumen de un proyecto de video performance realizado por cuatro estudiantes con el objetivo de intervenir en la cotidianidad de las personas y romper con la rutina mediante la representación de la infancia y la libertad, la espontaneidad y la alegría asociadas a ella. El proyecto buscaba generar una actitud diferente en busca de la felicidad a través de la simplicidad. Sin embargo, observaron que las personas rechazaron salir de sus esquemas y prejuicios sociales debido a su inmersión en la
BioCloth es una empresa que busca comercializar ropa biodegradable hecha de una fibra llamada Ingeo obtenida del maíz. La empresa planea ofrecer prendas deportivas y de vestir urbanas de doble faz a precios accesibles para proteger el medio ambiente y reducir emisiones de CO2. Su visión es expandirse a nivel nacional en 2 años y llegar a Latinoamérica en 5 años.
O texto discute como as tentações surgem dos próprios desejos das pessoas e não de Deus, levando ao pecado e à morte. Primeiro vem o desejo mal, depois a dúvida e engano, resultando em desobediência.
Un polinomio es la suma de varios monomios. Se compone de un número finito de variables y sólo utiliza las operaciones de adición, sustracción, multiplicación y potenciación con exponentes naturales. El grado de un polinomio es la mayor potencia de los monomios que lo componen. La resolución de ecuaciones algebraicas mediante polinomios se remonta a casi 4000 años atrás, aunque la notación actual data del siglo XV. Todo polinomio tiene al menos una raíz compleja, según el teorema fundamental del álgebra.
El documento presenta información sobre tres redes sociales: Google Buzz, Twitter y Facebook. Describe sus conceptos, usos, características, ventajas y desventajas. El objetivo es comparar los servicios que ofrecen estas plataformas y conocer cómo se utilizan. Google Buzz permite conversar y compartir recursos en línea de forma pública o privada. Twitter es una aplicación web gratuita de microblogging que combina blogs, redes sociales y mensajería instantánea. Facebook conecta amigos en todo el mundo a través de perfiles, muros, mens
La orografía se refiere a las características del relieve de una región, como sus montañas y colinas. Afecta el clima local de varias maneras: las montañas desvían los vientos ascendentes, lo que causa mayor nubosidad y precipitación en las laderas de barlovento, mientras que el lado de sotavento suele ser más seco. La orografía también influye en la formación de nubes como las lenticulares. El estudio de la orografía es útil para comprender mejor el territorio y planificar infraestructura.
Este documento explica cómo resolver ecuaciones algebraicas mediante el despeje de incógnitas. Define una ecuación como una igualdad matemática entre dos expresiones que contienen valores conocidos y desconocidos. Explica que resolver una ecuación es encontrar el valor de la incógnita que satisface la igualdad. A continuación, muestra ejemplos de cómo despejar la x, m, y otras incógnitas en diferentes ecuaciones mediante la adición y sustracción de términos en ambos lados de la igualdad.
1) A Terra tem forma de elipsóide com semieixos equatorial de 6378137 km e polar de 6356752 km. Isso resulta em uma excentricidade de 0,0818.
2) Um estudante representou a órbita elíptica da Terra em torno do Sol com barbante de 2m para o eixo maior, resultando em uma distância focal de 34 cm.
3) Usando a terceira lei de Kepler, calculou-se que Mercúrio está a aproximadamente 57,9 milhões de km do Sol.
29 ноября сооснователь некоммерческого научно-образовательного проекта для детей, имеющего уже сотни «клонов» в одной лишь Польше, показала в центре Digital October, какой интересной может быть система дополнительного школьного образования, и рассказала, как «Университет детей» в Москву пришел.
http://digitaloctober.ru/ru/events/knowledge_stream_umno_ne_po_detski
Сегодня он успешно совмещает карьеру ученого, преподавателя, финансового консультанта и управляет инвестициями друзей и знакомых на фондовой бирже, используя технологию мониторинга новых медиа, собирающую и анализирующую настроения тысяч мелких и крупных экономических агентов. 27 ноября он рассказал об этом в центре Digital October.
http://digitaloctober.ru/ru/events/knowledge_stream_finansovyy_geniy
15 ноября центр Digital October провел телемост с Джули Дирксен, исследователем и автором современных подходов к обучению, дающих результат.
http://digitaloctober.ru/ru/events/knowledge_stream_kak_uchitsya_vzroslomu
7 ноября куратор международного развития Coursera Инь Лу расскажет в центре Digital October, зачем ведущий провайдер знаний онлайн открывает образовательные лаборатории по всему свету, в том числе и в Москве.
http://digitaloctober.ru/ru/events/knowledge_stream_govorit_coursera
31 октября самый цитируемый ученый русского происхождения, известный эволюционный биолог Евгений Кунин рассказал в Digital October о постмодернистском взгляде на эволюционные процессы.
http://digitaloctober.ru/ru/events/knowledge_stream_evolyutsiya_po_sluchayu
Эволюционирует ли наш разум с распространением знаний и технологий? 19 сентября эксперт в области когнитивистики, профессор университетов Квебека и Саутгемптона Стивен Харнад ответил на этот вопрос в центре Digital October.
http://digitaloctober.ru/ru/events/knowledge_stream_kognitivnoe_neveroyatnoe
10 июня в центре Digital October состоялась лекция эксперта в области больших данных Бьярна Берга.
http://digitaloctober.ru/events/knowledge_stream_informatsiya_dlya_biznesa
Brad Hargreaves of General Assembly for Knowledge Stream spasibokep
General Assembly provides skills-based education in technology, business, and design through immersive courses. It has trained over 51,000 students through both full-time and evening programs across 8 campus locations. General Assembly works closely with employers to develop curriculum based on market needs and ensures graduates have relevant skills and access to job opportunities. The document provides examples of successful career outcomes for graduates of General Assembly's 12-week Web Development Immersive course and details its collaborative process for developing the Business Fundamentals and Tactics course with McKinsey.
Geoff Cook & Martin Bravo for Knowledge Streamspasibokep
This document discusses how brands can be thought of as people, with identities, personalities, and experiences. It provides examples of strong and challenged brands like Gilt and Fab, examining their identities, personalities, experiences, and results. Other case studies look at how brands like Warby Parker, Johnson & Johnson, and brand extensions engage customers. The document argues that successful future companies will focus on building strong identities, personalities, and experiences for their brands, just as people do.
Отчет и видеозапись выступления Кевина Вербаха на Knowledge Stream в Digital October 9 апреля - http://digitaloctober.ru/events/knowledge_stream_biznes_poigraem
«Технологии удалённого общения неизбежно возьмут своё в будущем. А те, кто освоит их раньше, получат больше шансов на успех», – уверен Максим Павловец, ведущий блога о бизнес-возможностях платформ для удаленного общения Webinarism.ru, ставший недавно обладателем гранта от программы «Менеджмент в сфере интернет-технологий». Подробнее - http://www.rma.ru/internet/news/8374/
Опыт Yahoo! по выходу из кризиса - презентация Марвина Ляо для RMAspasibokep
Yahoo намерен стать ведущим контент-провайдером, а также учится на примере противостояния MacOS/iOS и Android. Компании интересны стартапы, и она по-прежнему – как и другие лидеры мирового рынка – рассчитывает на успех в России. Об этом на открытой лекции, организованной факультетом «Менеджмент в сфере интернет-технологий», рассказал коммерческий Yahoo Марвин Ляо, отвечающий за работу интернет-гиганта на развивающихся рынках Европы, Ближнего Востока и Африки.
25 мая факультет «Менеджмент в сфере интернет-технологий» организует лекцию Марвина Ляо, коммерческого директора подразделения EMEA в Yahoo Global. Регистрация здесь http://www.rma.ru/yahoo_rma.php
В ходе встречи Марвин расскажет о международном опыте компании, том, как за последние 2-3 года поменялась ее стратегия работы на конкурентных рынках, а также ответит на вопросы аудитории.
Место проведения: технопарк DigitalOctober, Берсеневская набережная, 6/3. Начало в 19.00.
Презентация российских сервисов Yahoo! (2011-й). Предоставлено официальным лицом Yahoo! в России Денисом Адамовичем специально для факультета "Менеджмент в сфере интернет-технологий".
Оценка стартапов - Любовь Симонова (Almaz Capital) для Greenfield Feedback
Зеев Залевский для Knowledge Stream
1. Photonic Remote and Continuous
Biomedical Diagnostics
Zeev Zalevsky 1,2
1
Faculty of Engineering, Bar-Ilan University, Israel
2
SAOT, Friedrich-Alexander Universität Erlangen-Nürnberg,
Germany
1
2. Main collaborators:
Yevgeny Beiderman 1
Javier Garcia 2
Vicente Mico 2
Israel Margelith 1
Asaf Shahmoon 1
Alexander Douplik 3
Dan Cojoc 4
1
Faculty of Engineering, Bar-Ilan University, Israel
2
Departamento de Óptica, Universitat de València,
Spain
3
Ryerson University, Toronto, Canada
4
Trieste, Italy 2
3. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
3
4. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
4
5. Opto-Phone: Hearing with Light
Imaging
module
Camera
Sensor
Invisible L
aser Laser
projection
Any visible distance
5
6. Opto-Phone: Hearing with Light
Hearing with Light: Features
•The ultimate voice recognition system compatible to
“hear” human speech from any point of view (even from
behind).
•There is no restriction on the position of the system in
regards to the position of the sound source.
•Capable of hearing heart beats and knowing physical
conditions without physical contact for measuring.
6
7. Opto-Phone: Hearing with Light
Features- cont.
•Works clearly in noisy surroundings and even through
vacuum.
•Allows separation between plurality of speakers and
sounds sources.
•Works through glass window.
•Simple and robust system (does not include interferometer
in the detection phase).
7
8. Let ’s listen …from 80m
Cell phone Back part of neck
Counting…1,2,3,4,5,6
Counting…5,6,7
X - movement
1
0.5
0
-0.5
(Face (profile
-1
120 140 160 180 200 220 240 260 280 300 320
Heart beat pulse
Counting…5,6
taken from a throat
All recordings were done in a very noisy constriction site at distance of more
than 80m.
8
9. Results: Detection of
occluded objects I
(a). (b). (c).
(a). Camouflaged object. (b). Camouflage without the object. (c). The object (upper left part) and the low
resolution camouflaged scenery.
Spectrogram Spectrogram Spectrogram
0 0 0
2000 900
50 50 50
1800 12
800
100 100 100
1600
700 10
150 150 150
1400
Frequency [Hz]
Frequency [Hz]
Frequency [Hz]
600 200
200 200
1200 8
250 250 500 250
1000
6
300 300 400 300
800
350 350 300 350
600 4
400 400 400 200 400
2
450 200 450 100 450
500 500 500
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7
(d). Time [sec]
(e). Time [sec]
(f). Time [sec]
(d). The spectrogram of the camouflaged object with its engine turned on. (e). The spectrogram
of the object with its engine turned on and without the camouflage. (f). The spectrogram of the
camouflaged object without turning on its engine.
9
10. Results: Detection of
occluded objects II
(a). (b).
0 1 2 3 4 5 6 7 [sec]
(a). The scenario of the experiment. (b). Experimental results: upper recording is of the
camouflaged subject. Lower recording is the same subject without the camouflage.
10
11. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
11
12. Technological Description
•Unique technological platform allows remote
and continuous wearable monitoring of many
biomedical parameters simultaneously.
•It is based upon inspection of secondary
speckle pattern back reflected from skin near
main blood artery, after properly adjusting the
imaging optics.
•The biomedical monitoring capabilities include:
heart beats, breathing, blood pulse pressure,
glucose concentration, alcohol level, IOP, blood
coagulation (INR), oximetry, ICP etc.
•Unique patented IP and know how.
•Part of the applications have already been
commercialized. 12
13. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
13
14. Measuring of breathing from rat’s
cornea reflections
Detected rat’s breathing beating at
Noise level
frequency around 1.87Hz.
Reflected speckle pattern.
14
15. Measuring of heart beating from
human’s cornea reflections
(Abs) Spectrum (Abs) Spectrum (Abs) Spectrum
35 25 12
X: 1.502 X: 3.078
X: 1.522 Y: 11.68
30 Y: 33.65
Y: 19.96
10
20
25
8
15
Amplitude
Amplitude
Noise level
Amplitude
20
6
15
Noise level 10
4
10
5
2
5
0 0 0
-20 -15 -10 -5 0 5 10 15 20 -20 -15 -10 -5 0 5 10 15 20 -20 -15 -10 -5 0 5 10 15 20
Frequency [Hz] Frequency [Hz] Frequency [Hz]
Subject #1 (measurement taken while Subject #2 (measurement taken while Reference noise level (detected
subject was holding his breath) subject was holding his breath) reflection from a wall)
Detected heart beating of humans at frequency of around 1.5Hz.
10
20
30
40
Reflected speckles pattern.
50
60
10 20 30 40 50 60
15
16. Measuring breathing of pigs
The swine's
location
25
Breath Breath measured
20 The non-visible
40 m
laser system
15
10
m
B
u
n
p
h
e
a
s
r
t
i
5
Laser beam
0
1 2 3 4 5 6 7 8 9
Experiment
Statistical breathing experiment
16
17. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
17
18. Remote heart beats monitoring
The implemented optical configuration for
remote measuring of heart beats and blood
pulse pressure from subject’s hand
Laser
Camera
50 cm
Hand
3
2
Temporal plot of the outcome from the
2.5
0
system used in the clinical trials for two
2
different participants.
Amplitude [pix]
Amplitude [pix]
1.5 -2
1 -4
0.5
-6
0
-8
-0.5
-10
-1
0 1 2 3 4 0 1 2 3 4
Time [sec] Time [sec]
18
19. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
19
20. Glucose level monitoring
Temporal plot of the outcome from the system used in the clinical tests with the graphical description of the observed
parameters.
20
21. Glucose level monitoring
40 210
35 190
Glucose [mg/dl]
30 170
25 150
20 Glucose /10 130
,
15 Param.6 110
10 90
m
G
m
d
o
u
A
0
1
e
s
c
d
u
p
a
s
e
]
[
/
l
;
]
[
t
i
l
5 70
0 50
0 5 10 15 20 25 30 0 5 10 15 20 25 30
Time [min] time [minutes]
Stability of the system: constant glucose level in blood (denoted Data of subject #1: Glucose level in blood and amplitude
by blue line with triangles) and the estimated parameter 6 of positive peak (parameter #1). Glucose level is denoted
(denoted by magenta line with rectangles). Glucose level is by blue line with triangles and the optically measured
given in units of 0.1[ml/dl] (representing a constant level of 100 parameter is denoted by magenta line with rectangles.
[ml/dl), while the estimated optical values are given in pixels.
21
22. Glucose level monitoring
210 210
190 190
Glucose [mg/dL]
Glucose [mg/dl]
170 170
150 150
130 130
,
110 110
90 90
70 70
50 50
0 10 20 30 40 0 5 10 15 20 25 30
time [minutes] time [minutes]
22
Data of subject #3: Glucose level in blood and amplitude of positive peak Data of subject #1: Glucose level in blood and
(parameter #1). Glucose level is denoted by blue line with triangles and the amplitude of positive peak (parameter #1). Glucose
optically measured parameter is denoted by magenta line with rectangles. level is denoted by blue line with triangles and the
optically measured parameter is denoted by magenta
190 line with rectangles.
170
Glucose [mg/dl]
150
130
110
90 Data of subject #4: Glucose level in blood and amplitude of
70 positive peak (parameter #1). Glucose level is denoted by blue
50 line with triangles and the optically measured parameter is
0 5 10 15 20 25 30 denoted by magenta line with rectangles.
time [minutes]
22
23. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
23
24. Blood pulse pressure
measurement
M , Corr(M , ∆) = 0.99507
140
Systolic
Diastolic
120 ∆ = S-D
Amplitude [mmHg]
100
80
60
40
20
-50 0 50 100 150 200 250 300 350 400
Time [sec]
An example of the obtained remote blood pulse pressure measurement using the proposed device for one subject
participating in the clinical test group. The reference pulse pressure is shown by the green curve (denoted as ∆) was
obtained using manual sleeve based reference measurement device. The blue curve (denoted as M) is the measurement
obtained using the proposed optical technique. The time duration of the measurement was 350sec. The sampling of the
camera was performed at 300Hz. One may see that strong correlation exists between the green (reference) curve and the
blue curve obtained by the developed approach.
24
25. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
25
26. Remote IOP monitoring
The proposed experimental configuration for
remote continuous monitoring of the IOP.
Changing IOP via applying mechanical pressure
on the sclera.
Changing IOP via modifying the height of an
infusion bug.
26
27. Remote IOP monitoring
Data amplitude:
8.02 10.7 11.27 11.6 9.35 7.26 7.22 6.46
With infusion bag
With applied pressure
Experimentally extracted readout compared to
absolute reference IOP measurement obtained
Experimentally extracted readout with Goldmann tonometer.
obtained when changing the height of
the infusion bag every 500 samples.
27
28. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
28
29. Detection of malaria
An example of one out of the 20 relevant inspected parameters. Left: Healthy RBC. Right: Infected RBC.
29
30. Detection of malaria
Separation between infected and
healthy cells. Plotting the length of the
vectors versus cells’ index.
30
31. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
31
32. Remote alcohol level monitoring
(a). (b).
(a). The side (left) and top (right) view of the experimental setup. (b). Typical temporal beating signals extracted
using the proposed remote optical sensing device, before (left) and after (right) the effect of alcohol obtained
over the same subject.
32
33. Remote alcohol level monitoring
Definition of the Ratio wid (through the ratio between the main STD of background noises: long duration test with
and the secondary negative peak’s temporal positions), Main error bars representing the std values of the
sec peak ratio (through the ratio between the main negative measured data.
peak amplitude and the secondary positive peak’s amplitude),
and Standard deviation of background noise (STD) parameters.
33
37. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
37
38. Multi-Functional Probe
The edge of the fabricated micro
probe having approximately 5,000
cores while each one of them is
being used as light transmitting
channel (each core is a single
pixel in the formed image). In this
image each core transmits red
channel of light at wavelength of
632nm.
50µm
Laser (632nm) Beam Expander Mirror Laser Controller Camera
Input plane Output plane
Multi core probe F Image
Object
Sample
Location
U1 U2 V
Beam Splitter
Probe Location
1 1 1
+ = Objective Lens
U1 + U 2 V F
38
39. Multi-Functional Probe-
experiments
Experimental results of images transmitted backwards by the proposed micro probe. The scanned objects are as follows;
From left to right: black vertical lines, black rectangles, horizontal black lines, black lines and black rectangle appearing
in the left side of the backwards transmitted image.
5µm
2µm
Experimental results of images with Fe beads having diameter of 1µm imaged
through an agar solution.
39
40. Phantom fabrication
(a) (b) (c)
(a) Fabricated phantom. (b) shows a 3D view sketch of the phantom having two drilled channels with diameter of
400µm each. One longitudinal channel (along the x axis) while another angled channel was made making both
channel crossed inside the phantom. The openings indicated as “in” and “out” enable the connection of microfluidic
system. (c) shows a cross-sectional schematic view of the fabricated phantom.
40
41. Experimental results with
phantom
Experimental results of Fe micro
particles imaged inside a drilled
phantom
Imaging of a manipulated micro wire (indicated by
the solid arrows) inside an hemoglobin mixture.
(a) Top view microscope image of the resolution target. (b) imaging
Imaging of fluorescence protein. HEK 293 cells transfected of the resolution target using the microendoscope device. Inset.
with pEGFP-N3. Left: Top view microscope image. Right: Zoom image of the encompass area. Scales bar of (a) and (b) are 10
Imaging using the microendoscope device. Scales bar of left µm and 20 µm, respectively.
and right image are 50 and 20 µm, respectively.
41
42. Experimental results with
phantom
Monitoring different hemoglobin concentrations inside the phantom.
42
43. In-vivo experimental results
Imaging along a blood vein
of a chicken wing. The solid
arrows indicate the blood
vein, while the dashed arrows
as well as the labeling letter
indicate the cascading point
between the images for
constructing an image with a
larger field of view
43
46. Outline
•“Hearing” with light – Introduction
•Biomedical monitoring:
•Introduction
•Measuring of breathing
•Heart beats monitoring
•Glucose level monitoring
•Blood pulse pressure monitoring
•IOP monitoring
•Malaria detection
•Alcohol detection
•Oximetry and coagulation of blood
•Micro endoscope
•Conclusions
46
47. Conclusions:
• A new technology for accurate remote and continuous sensing of
movements was developed.
• The technique is based upon processing of back reflected
secondary speckles statistics.
• We demonstrated remote estimation of breathing, heart beating,
blood pulse pressure, alcohol and glucose concentration in the
blood stream, intra-ocular pressure measurement, oximetry,
coagulation of blood etc.
• To extract precise absolute value for the measured biomedical
parameters periodic personalized calibration is needed every 2-3
years.
• Ultra thin and multi-functional micro endoscope for minimally 47
invasive medical treatment and diagnostics was presented