This document discusses heterogeneity in non-small cell lung cancer (NSCLC) and the importance of personalized treatment based on molecular profiling. It presents four hypothetical patients with stage IV NSCLC who differ in their clinical features, molecular characteristics, and appropriate therapies. For example, a younger female never-smoker with an EGFR mutation should receive an EGFR tyrosine kinase inhibitor, while an older male smoker with a KRAS mutation may not benefit from such targeted therapies. The document emphasizes that molecular testing is needed to determine the optimal treatment for each patient's specific cancer.
El documento analiza los problemas del sistema educativo mexicano. A pesar de que México gasta más del 7% de su PIB en educación, el 44% de las escuelas son multigrado y hay gran desigualdad social. El gasto público en educación ha generado resultados ineficientes en términos de cobertura, equidad, calidad y sindicatos. Se necesitan reformas para mejorar la educación en México.
This document discusses heterogeneity in non-small cell lung cancer (NSCLC) and the importance of personalized treatment based on molecular profiling. It presents four hypothetical patients with stage IV NSCLC who differ in their clinical features, molecular characteristics, and appropriate therapies. For example, a younger female never-smoker with an EGFR mutation should receive an EGFR tyrosine kinase inhibitor, while an older male smoker with a KRAS mutation may not benefit from such targeted therapies. The document emphasizes that molecular testing is needed to determine the optimal treatment for each patient's specific cancer.
El documento analiza los problemas del sistema educativo mexicano. A pesar de que México gasta más del 7% de su PIB en educación, el 44% de las escuelas son multigrado y hay gran desigualdad social. El gasto público en educación ha generado resultados ineficientes en términos de cobertura, equidad, calidad y sindicatos. Se necesitan reformas para mejorar la educación en México.
This document appears to be a 21 page document with page numbers listed consecutively from 1 to 21. The document provides page numbers but no other discernible content, context, or information across its 21 numbered pages.
Collaborate with local non-profit organization, Habitat For Humanity
- Provide leadership to team of architect and construction management students
- Perform a scope of work analysis, re-design areas in each home as needed, select materials, draft measured drawings, determine quantities and perform other duties as required by the partner organization
Μαθητές της Α΄ Γυμνασίου του 7ου Γυμνασίου Θεσσαλονίκης παρουσιάζουν τις απόψεις και τα αποτελέσματα των "ερευνών" πάνω στα ΣΥΝΑΙΣΘΗΜΑΤΑ στα πλαίσια του μαθήματος Σχολική και Κοινωνική Ζωή
El documento anuncia un taller coral que tendrá lugar del 1 al 7 de junio de 2015 en La Nucia y Altea. El taller contará con la presencia del coro Philharmonia Chorus de Londres y su director Stefan Bevier. Durante el taller se trabajará la obra Carmina Burana de Carl Orff, que se presentará en dos conciertos. El taller tiene como objetivos la formación musical continua y la difusión a través de actuaciones.
As the aviation community continues to implement Next Generation Air Transportation System (NextGen) initiatives, operators want to know what the initiatives are and how they affect individual operators. The question always comes down to value: If I upgrade my aircraft, what will I get for the often substantial investment?
Datalink services are available in most of the world’s oceanic routes and in some domestic airspace, as well. The services provide invaluable support at transfer points where aircraft enter or exit domestic airspace and enter oceanic. The enhanced communication abilities aid the ATC on both sides of tracks and particularly when a controller at one center hands off an aircraft to another ATC center because with a FANS-equipped aircraft, the handoff occurs seamlessly behind the scenes.
Along the routes that have not yet been mandated for FANS, the flight crew has to call an ATC and give verbal updates as to their whereabouts with no support from ground surveillance. This lack of accurate position data is a problem because if an ATC doesn’t know exactly where an aircraft is, the ATC has to maintain greater distance between aircraft. With FANS, an ATC can track aircraft along the entire route and safely and efficiently track and accommodate more aircraft in the airspace. The majority of these enhanced services are available to FANS 1/A-equipped aircraft. Ground facilities around the world are upgrading to FANS work stations.
Which datalink service a particular operator selects depends entirely on what equipment is available for the type of aircraft.
FLY SAFE!!!!
MHA is a high availability solution for MySQL that provides almost no data loss during failover. It uses a monitor to check the state of nodes, find the latest slave, and perform failover in parallel to minimize downtime. MHA recovers the new master by finding the most up-to-date slave and recovering its relay logs. It also supports interacting with applications through user-defined scripts to notify clients of failovers.
El documento describe los componentes principales del sistema circulatorio, incluyendo el corazón, las arterias, las venas y su relación. Explica la configuración interna del corazón, con secciones sobre los ventrículos, orificios auriculoventriculares, orificios ventriculares y las columnas carnosas de los ventrículos. También cubre las aurículas derecha e izquierda y el sistema de conducción del corazón.
This document describes a study that derived tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. Researchers transitioned several human embryonic stem cell and induced pluripotent stem cell lines to xeno-free substrate and media conditions, and found that the cells retained pluripotency and normal karyotype. The cells were then induced to form neuralized spheres containing primitive neural precursors using EGF and FGF. Further differentiation generated adherent human neural stem cells that could differentiate into astrocytes, neurons, and oligoprogenitors, demonstrating their multipotency. This study provides a method for deriving neural cells and stem cells from human pluripotent cells under animal product
Este documento presenta la estructura y objetivos de 7 unidades de estudio. Cada unidad se centra en un tema comunicativo como la narración, la descripción o la poesía. Las unidades incluyen objetivos, competencias, contenidos conceptuales, procedimentales y actitudinales. Los contenidos cubren temas lingüísticos y literarios y estrategias para mejorar la expresión y comprensión oral y escrita.
This document appears to be a 21 page document with page numbers listed consecutively from 1 to 21. The document provides page numbers but no other discernible content, context, or information across its 21 numbered pages.
Collaborate with local non-profit organization, Habitat For Humanity
- Provide leadership to team of architect and construction management students
- Perform a scope of work analysis, re-design areas in each home as needed, select materials, draft measured drawings, determine quantities and perform other duties as required by the partner organization
Μαθητές της Α΄ Γυμνασίου του 7ου Γυμνασίου Θεσσαλονίκης παρουσιάζουν τις απόψεις και τα αποτελέσματα των "ερευνών" πάνω στα ΣΥΝΑΙΣΘΗΜΑΤΑ στα πλαίσια του μαθήματος Σχολική και Κοινωνική Ζωή
El documento anuncia un taller coral que tendrá lugar del 1 al 7 de junio de 2015 en La Nucia y Altea. El taller contará con la presencia del coro Philharmonia Chorus de Londres y su director Stefan Bevier. Durante el taller se trabajará la obra Carmina Burana de Carl Orff, que se presentará en dos conciertos. El taller tiene como objetivos la formación musical continua y la difusión a través de actuaciones.
As the aviation community continues to implement Next Generation Air Transportation System (NextGen) initiatives, operators want to know what the initiatives are and how they affect individual operators. The question always comes down to value: If I upgrade my aircraft, what will I get for the often substantial investment?
Datalink services are available in most of the world’s oceanic routes and in some domestic airspace, as well. The services provide invaluable support at transfer points where aircraft enter or exit domestic airspace and enter oceanic. The enhanced communication abilities aid the ATC on both sides of tracks and particularly when a controller at one center hands off an aircraft to another ATC center because with a FANS-equipped aircraft, the handoff occurs seamlessly behind the scenes.
Along the routes that have not yet been mandated for FANS, the flight crew has to call an ATC and give verbal updates as to their whereabouts with no support from ground surveillance. This lack of accurate position data is a problem because if an ATC doesn’t know exactly where an aircraft is, the ATC has to maintain greater distance between aircraft. With FANS, an ATC can track aircraft along the entire route and safely and efficiently track and accommodate more aircraft in the airspace. The majority of these enhanced services are available to FANS 1/A-equipped aircraft. Ground facilities around the world are upgrading to FANS work stations.
Which datalink service a particular operator selects depends entirely on what equipment is available for the type of aircraft.
FLY SAFE!!!!
MHA is a high availability solution for MySQL that provides almost no data loss during failover. It uses a monitor to check the state of nodes, find the latest slave, and perform failover in parallel to minimize downtime. MHA recovers the new master by finding the most up-to-date slave and recovering its relay logs. It also supports interacting with applications through user-defined scripts to notify clients of failovers.
El documento describe los componentes principales del sistema circulatorio, incluyendo el corazón, las arterias, las venas y su relación. Explica la configuración interna del corazón, con secciones sobre los ventrículos, orificios auriculoventriculares, orificios ventriculares y las columnas carnosas de los ventrículos. También cubre las aurículas derecha e izquierda y el sistema de conducción del corazón.
This document describes a study that derived tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. Researchers transitioned several human embryonic stem cell and induced pluripotent stem cell lines to xeno-free substrate and media conditions, and found that the cells retained pluripotency and normal karyotype. The cells were then induced to form neuralized spheres containing primitive neural precursors using EGF and FGF. Further differentiation generated adherent human neural stem cells that could differentiate into astrocytes, neurons, and oligoprogenitors, demonstrating their multipotency. This study provides a method for deriving neural cells and stem cells from human pluripotent cells under animal product
Este documento presenta la estructura y objetivos de 7 unidades de estudio. Cada unidad se centra en un tema comunicativo como la narración, la descripción o la poesía. Las unidades incluyen objetivos, competencias, contenidos conceptuales, procedimentales y actitudinales. Los contenidos cubren temas lingüísticos y literarios y estrategias para mejorar la expresión y comprensión oral y escrita.