c
o
n
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e
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f
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c
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r
s
N d
i
s
e
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e
i
m
m
o
b
i
l
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n
w
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h
a
u
r
a
S
m
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g
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a
n
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u
s
>
3
0
k
g
/
m
2
o
r
a
d
e
q
u
a
t
e
l
y
r
i
s
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e
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r
t
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t
M
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n
-
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>
3
5
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g
e
<
3
5
C
u
r
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e
n
t
B
M
I
>
1
6
0
/
>
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0
1
4
0
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1
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9
/
9
0
-
9
9
M
u
l
t
i
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e I
s
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e
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c
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i
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e
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e
n
t
P
r
e
-
1
1
1
1
1
1
1
1 1 1 1 1 1
1
1
1
1
1
4
A
1
2
M
1
1
1
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1
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M
2 2
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L
2
1
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2
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1
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3
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1
3
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2
M
,
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1
1
1
2
1
2
1
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M
2
M
2
3
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2
1
3
4
1
4
S
1
3
R
2
2
Q
2
4
3
3
/
4 4
4
4
4
4
3
/
4
K
,
A
4
J
4
2
D
I
S
E
A
S
E
C
A
N
C
E
R
C
A
N
C
E
R
H
E
A
D
A
C
H
E
S
M
O
K
I
N
G
D
I
A
B
E
T
E
S
Q
O
B
E
S
I
T
Y
H
Y
P
E
R
T
E
N
S
I
O
N
O
C
A
R
D
I
O
V
A
S
C
U
L
A
R
V
E
N
O
U
S
T
H
R
O
M
B
O
E
M
B
O
L
I
S
M
L
I
V
E
R
D
I
S
E
A
S
E
S
B
R
E
A
S
T
C
E
R
V
I
C
A
L
How to use this wheel
The wheel matches up the contraceptive methods, shown on the inner
disk, with specific medical conditions or characteristics shown around
the outer rim. The numbers shown in the viewing slot tell you whether
the woman who has this known condition or characteristic is able to
start use of the contraceptive method:
CATEGORY WITH CLINICAL JUDGEMENT
WITH LIMITED
CLINICAL JUDGEMENT
1 Use method in any circumstance YES
(Use the method)
2 Generally use method
3
Use of method not usually
recommended unless other more
appropriate methods are not
available or not acceptable
NO
(Do not use the
method)
4 Method not to be used
Categories 1 and 4 are clearly defined recommendations. For categories
2 or 3, greater clinical judgement will be needed and careful follow-up
may be required. If clinical judgement is limited, categories 1 and 2 both
mean the method can be used, and categories 3 and 4 both mean the
method should not be used.
No restrictions for some conditions: there are many medical conditions
when ALL methods can be used (that is, all the methods are either a
category 1 or 2). Some of these conditions are listed on the back of the
wheel.
With few exceptions, all women can safely use emergency
contraception, barrier and behavioural methods of contraception,
including lactational amenorrhoea method; for the complete list of
recommendations, please see the full document.
Only correct and consistent use of condoms, male or female,
protect against STI/HIV. If there is a risk of STI/HIV, condom use is
recommended.
MEDICAL ELIGIBILITY CRITERIA WHEEL
FOR CONTRACEPTIVE USE
WHO
2015
c
o
n
v
u
l
s
a
n
t
s
T
<
1
8
y
e
a
r
s
abortion
STIs
vaginitis
S
t
a
g
e
3
o
r
4
t
h
e
r
a
p
y
R
i
f
a
b
u
t
i
n
a
n
t
i
-
t
o
a
g
e
<6 months
<6 weeks
<4 weeks
and post-
risk of
and
C
h
l
a
m
ydia
A
n
t
i
r
e
t
r
o
v
i
r
a
l
R
i
f
a
m
p
i
c
i
n
/
C
e
r
t
a
i
n
U
n
e
x
p
l
a
i
n
e
d
M
e
n
a
r
c
h
e
6 weeks to
4 weeks to
48 hours to
<48 hours
Puerperal
Current
Increased
Other STIs
G
o
n
o
r
rhoea
W
H
O
N
E
O
P
L
A
S
I
A
F
I
B
R
O
I
D
S
B
L
E
E
D
I
N
G
INFECTIONS
INFECTIONS
INFECTIONS
S
EXUALLY TRANSMITTED
M
E
D
I
C
A
T
I
O
N
S
C
E
R
V
I
C
A
L
U
T
E
R
I
N
E
V
A
G
I
N
A
L
A
D
O
L
E
S
C
E
N
T
S
NULLI
P
A
R
I
T
Y
POSTPARTUM AND BREASTFEEDING
SEPSIS
P I DC
H
I
V
Progestogen-only pills 2 POP
P
r
o
g
e
stin-only injectables 3 DMPA (IM, SC) /
N
E
T
-
E
N
L
e
v
o
n
orgestrel IUD 2E
LNG-IUD
C
o
pper IUD 1 Cu-IUD
Implants 2 LNG / ETG
C
o
m
b
i
n
e
d
hormonal contraceptives 4D
Pill, patch, ring, injec
t
a
b
l
e
(
C
O
C
,
P
,
C
V
R
,
C
I
C
)
ISBN 978 92 4 154925 7
WHO Library Cataloguing-in-Publication Data
WHO medical eligibility criteria wheel for contraceptive use – 2015 update.
1.Contraception - methods. 2.Family Planning Services - methods. 3.Eligibility Determination - standards.
I.World Health Organization.
ISBN 978 92 4 154925 7 (NLM classification: WP 630)
© World Health Organization 2015
All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be
purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
(tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int).
Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution–
should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index.html).
The designations employed and the presentation of the material in this publication do not imply the expression of any
opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or
area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps
represent approximate border lines for which there may not yet be full agreement.
The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or
recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors
and omissions excepted, the names of proprietary products are distinguished by initial capital letters.
All reasonable precautions have been taken by the World Health Organization to verify the information contained in this
publication. However, the published material is being distributed without warranty of any kind, either expressed or implied.
The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health
Organization be liable for damages arising from its use.
Printed in Italy
MEDICAL ELIGIBILITY CRITERIA WHEEL
FOR CONTRACEPTIVE USE
WHO
2015
c
o
n
v
u
l
s
a
n
t
s
T
<
1
8
y
e
a
r
s
abortion
STIs
vaginitis
S
t
a
g
e
3
o
r
4
t
h
e
r
a
p
y
R
i
f
a
b
u
t
i
n
a
n
t
i
-
t
o
a
g
e
<6 months
<6 weeks
<4 weeks
and post-
risk of
and
C
h
l
a
m
ydia
A
n
t
i
r
e
t
r
o
v
i
r
a
l
R
i
f
a
m
p
i
c
i
n
/
C
e
r
t
a
i
n
U
n
e
x
p
l
a
i
n
e
d
M
e
n
a
r
c
h
e
6 weeks to
4 weeks to
48 hours to
<48 hours
Puerperal
Current
Increased
Other STIs
G
o
n
o
r
rhoea
W
H
O
N
E
O
P
L
A
S
I
A
F
I
B
R
O
I
D
S
B
L
E
E
D
I
N
G
INFECTIONS
INFECTIONS
INFECTIONS
S
EXUALLY TRANSMITTED
M
E
D
I
C
A
T
I
O
N
S
C
E
R
V
I
C
A
L
U
T
E
R
I
N
E
V
A
G
I
N
A
L
A
D
O
L
E
S
C
E
N
T
S
NULLI
P
A
R
I
T
Y
POSTPARTUM AND BREASTFEEDING
SEPSIS
P I DC
H
I
V
Progestogen-only pills 2 POP
P
r
o
g
e
stin-only injectables 3 DMPA (IM, SC) /
N
E
T
-
E
N
L
e
v
o
n
orgestrel IUD 2E
LNG-IUD
C
o
pper IUD 1 Cu-IUD
Implants 2 LNG / ETG
C
o
m
b
i
n
e
d
hormonal contraceptives 4D
Pill, patch, ring, injec
t
a
b
l
e
(
C
O
C
,
P
,
C
V
R
,
C
I
C
)
ISBN 978 92 4 154925 7
WHO Library Cataloguing-in-Publication Data
WHO medical eligibility criteria wheel for contraceptive use – 2015 update.
1.Contraception - methods. 2.Family Planning Services - methods. 3.Eligibility Determination - standards.
I.World Health Organization.
ISBN 978 92 4 154925 7 (NLM classification: WP 630)
© World Health Organization 2015
All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be
purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland
(tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int).
Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution–
should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index.html).
The designations employed and the presentation of the material in this publication do not imply the expression of any
opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or
area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps
represent approximate border lines for which there may not yet be full agreement.
The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or
recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors
and omissions excepted, the names of proprietary products are distinguished by initial capital letters.
All reasonable precautions have been taken by the World Health Organization to verify the information contained in this
publication. However, the published material is being distributed without warranty of any kind, either expressed or implied.
The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health
Organization be liable for damages arising from its use.
Printed in Italy
Use the method in any
circumstance
Use of the method not usually
recommended unless other, more
appropriate methods are not
available or acceptable
1
Generally use the method
2
3
4 Method NOT to be used
WHO Medical Eligibility Criteria Wheel
for contraceptive use, 2015
These methods do not protect against STI/HIV. If there is a risk of STI/HIV, the
correct and consistent use of condoms, male or female, is recommended.
C
o
m
b
i
n
e
d
h
ormonal contraceptives Pill, patch, ring, injectab
l
e
(
C
O
C
,
P
,
C
V
R
,
C
I
C
)
P
rogestogen-only pills POP
P
r
o
g
e
s
t
o
g
en-only injectables DMPA (IM, SC) / N
E
T
-
E
N
L
e
v
o
n
o
rgestrel IUD LNG-IUD
C
o
pper IUD Cu-IUD
Implants LNG / ETG
c
o
n
v
u
l
s
a
n
t
s
T
c
o
n
t
r
o
ll
e
d
f
a
c
t
o
r
s
N
d
i
s
e
a
s
e
i
m
m
o
b
i
l
i
z
a
i
o
n
<
1
8
y
e
a
r
s
abortion
STIs
vaginitis
S
t
a
g
e
3
o
r
4
t
h
e
r
a
p
y
R
i
f
a
b
u
t
i
n
a
n
t
i
-
w
i
t
h
a
u
r
a
S
m
i
g
r
a
n
o
u
s
>
3
0
k
g
/
m
2
o
r
a
d
e
q
u
a
t
e
l
y
r
i
s
k h
e
a
r
t
w
i
t
h
p
r
o
l
o
n
g
e
d
a
c
u
t
e
/
fl
a
r
e
t
u
m
o
u
r
I
t
r
e
a
t
m
e
n
t
t
o
a
g
e
<6 months
<6 weeks
<4 weeks
and post-
risk of
and
C
h
l
a
m
ydia
A
n
t
i
r
e
t
r
o
v
i
r
a
l
R
i
f
a
m
p
i
c
i
n
/
C
e
r
t
a
i
n
M
i
g
r
a
i
n
e
N
o
n
-
A
g
e
>
3
5
A
g
e
<
3
5
C
u
r
r
e
n
t
B
M
I
>
1
6
0
/
>
1
0
0
1
4
0
-
1
5
9
/9
0
-
9
9
M
u
l
t
i
p
l
e I
s
c
h
a
e
m
i
c
S
t
r
o
k
e
M
a
j
o
r
s
u
r
g
e
r
y
A
c
u
t
e
H
i
s
t
o
r
y
H
e
p
a
t
i
t
i
s
L
i
v
e
r
C
u
r
r
e
n
t
P
r
e
-
U
n
e
x
p
l
a
i
n
e
d
M
e
n
a
r
c
h
e
6 weeks to
4 weeks to
48 hours to
<48 hours
Puerperal
Current
Increased
Other STIs
G
o
n
o
rrhoea
W
H
O
2
4
A
3
A
2
/
3
A
Z
1
1
1
1
1
1
1
1
1 1 1 1 1 1
1
1
1
1
1
4
A
1
1
H
4
A
2
2
1
1
3
1
4
4A
2/3B
2
4
A
3
A
2
/
3
A
Z
1
1
2
M
1
1
1
2
1
2 1 2 2
M
2
2
3
L
2
1
3
4
4
A
2
1
H
4
A
2
2
1
1
3
2E
4
4A
2/3B
1
1
1
-
2
Y
2
2
V
2
M
1
1
1
2
1
2
1 2 2
M
2
M
2
3
L
2
1
3
4
2
2
1
3
1
1
1
2
2
2
1
1
1
1
1
1
1
-
2
Y
1
-
2
W
1-
2
W,V
2
M
1
1
1
2
Q
1
P
3
2 3 3 3
2
3
L
2
1
3
4
2
2
1
3
2
1
1
3
3
3
1
1
1
1
1
1
1
-
2
Y
3
3
V
2
M,S
1
1
1
2
1
2
1 2 2
M
2
M
2
3
L
2
1
3
4
1
1
1
2
1
1
1
2
2
2
1
1
1
1
1
1
1
-
2
Y
3
X
3
U
4
S
1
3
R
2
2
Q
2
4
3
3/
4 4
4
4
4
4
3
/
4
K
,
A
4
J
4
2
2
1
2
1
1
3 G
4 F
4D,F
4D
1
1
1
1
D
I
S
E
A
S
E C
A
N
C
E
R
C
A
N
C
E
R
N
E
O
P
L
A
S
I
A
F
I
B
R
O
I
D
S
B
L
E
E
D
I
N
G
INFECTIONS
INFECTIONS
INFECTIONS
SEXUALLY TRANSMITTED
M
E
D
I
C
A
T
I
O
N
S
H
E
A
D
A
C
H
E
S
M
O
K
I
N
G
D
I
A
B
E
T
E
S
Q
O
B
E
S
I
T
Y
H
Y
P
E
R
T
E
N
S
I
O
N
O
C
A
R
D
I
O
V
A
S
C
U
L
A
R
V
E
N
O
U
S
T
H
R
O
M
B
O
E
M
B
O
L
I
S
M L
I
V
E
R
D
I
S
E
A
S
E
S
B
R
E
A
S
T
C
E
R
V
I
C
A
L
C
E
R
V
I
C
A
L
U
T
E
R
I
N
E
V
A
G
I
N
A
L
A
D
O
L
E
S
C
E
N
T
S
NULLI
P
A
R
I
T
Y
POSTPARTUM AND BREASTFEEDING
SEPSIS
P I DC
H
I
V
Conditions that are category 1 and 2 for all methods (method can be used)
Reproductive Conditions: Benign breast disease or undiagnosed mass • Benign ovarian tumours, including cysts • Dysmenorrhoea • Endometriosis • History
of gestational diabetes • History of high blood pressure during pregnancy • History of pelvic surgery, including caesarean delivery • Irregular, heavy or
prolonged menstrual bleeding (explained) • Past ectopic pregnancy • Past pelvic inflammatory disease • Post-abortion (no sepsis) • Postpartum ≥ 6 months
Medical Conditions: Depression • Epilepsy • HIV asymptomatic or mild clinical disease (WHO Stage 1 or 2) • Iron-deficiency anaemia, sickle-cell disease
and thalassaemia • Malaria • Mild cirrhosis • Schistosomiasis (bilharzia) • Superficial venous disorders, including varicose veins • Thyroid disorders
• Tuberculosis (non-pelvic) • Uncomplicated valvular heart disease • Viral hepatitis (carrier or chronic)
Other: Adolescents • Breast cancer family history • Venous thromboembolism (VTE) family history • High risk for HIV
• Surgery without prolonged immobilization • Taking antibiotics (excluding rifampicin/rifabutin)
With few exceptions, all women can safely use emergency contraception, barrier and behavioural methods of contraception, including
lactational amenorrhoea method; for the complete list of recommendations, please see the full document.
“Combined” is a combination of ethinyl estradiol & a progestogen.
CIC: combined injectable contraceptive COC: combined oral contraceptive pill
Cu-IUD: copper intrauterine device CVR: combined contraceptive vaginal ring
DMPA (IM, SC): depot medroxyprogesterone acetate, intramuscular or subcutaneous
ETG: etonogestrel LNG: levonorgestrel LNG-IUD: levonorgestrel intrauterine device
NET-EN: norethisterone enanthate P: combined contraceptive patch
POP: progestogen-only pill
A If condition develops while using method, can continue using it during treatment.
B If very high likelihood of exposure to gonorrhoea or chlamydia =3.
C If past pelvic inflammatory disease (PID) all methods =1, including IUDs.
D If <3 wks, not breastfeeding & no other VTE risk factors =3.
E If not breastfeeding =1.
R If <15 cigarettes/day CIC =2. If ≥15 cigarettes/day
COC/P/CVR =4.
S Aura is focal neurological symptoms, such as flickering
lights. If no aura & age <35 COC/P/CVR, CIC =2, POP =1.
If no aura & age ≥35 COC/P/CVR, CIC =3, POP =1.
T Barbituates, carbamazepine, oxcarbazepine, phenytoin,
primidone, topiramate & lamotrigine.
U If barbituates, carbamazepine, oxcarbazepine, phenytoin,
primidone or topiramate CIC =2.
V If lamotrigine =1.
W DMPA =1, NET-EN =2.
X CICs =2.
Y If antiretroviral therapy with EFV, NVP, ATV/r, LPV/r, DRV/r,
RTV: COC/P/CVR, CIC, POP, NET-ET, Implants =2; DMPA =1.
For all NRTIs, ETR, RPV, RAL each method =1. See jacket
for full names of medications.
Z If WHO Stage 3 or 4 (severe or advanced HIV clinical
disease) IUD =3.
G If ≥6 wks & not breastfeeding =1.
H If uterine cavity distorted preventing insertion =4.
I Refers to hepatocellular adenoma (benign) or carcinoma/
hepatoma (malignant).
J If adenoma CIC =3, if carcinoma/hepatoma CIC =3/4.
K CIC =3.
L If established on anticoagulation therapy =2.
M If condition developed while on this method, consider
switching to non-hormonal method.
N Risk factors: older age, smoking, diabetes, hypertension,
obesity & known dyslipidaemias.
O If cannot measure blood pressure & no known history
of hypertension, can use all methods. Either systolic or
diastolic blood pressure may be elevated.
P If age <18 yrs & obese DMPA/NET-EN =2.
Q For insulin-dependent & non-insulin-dependent. If
complicated or >20 yrs duration, COC/P/CVR, CIC =3/4;
DMPA, NET-EN =3.
F If 3 to <6 wks, not breastfeeding & no other VTE risk factors =2, with other VTE risk factors =3.
About this wheel
This wheel contains the medical eligibility criteria for starting use of contraceptive methods, based on Medical Eligibility
Criteria for Contraceptive Use, 5th
edition (2015), one of WHO’s evidence-based guidelines. It guides family planning providers
in recommending safe and effective contraception methods for women with medical conditions or medically-relevant
characteristics.
The wheel includes recommendations on initiating use of nine common types of contraceptive methods:
1. Combined pills, COC (low dose combined oral contraceptives, with ≤ 35 μg ethinyl estradiol)
2. Combined contraceptive patch, P
3. Combined contraceptive vaginal ring, CVR
4. Combined injectable contraceptives, CIC
5. Progestogen-only pills, POP
6. Progestogen-only injectables, DMPA (IM,SC)/NET-EN (depot medroxyprogesterone acetate intramuscular or subcutaneous
or norethisterone enantate intramuscular)
7. Progestogen-only implants, LNG/ETG (levonorgestrel or etonogestrel)
8. Levonorgestrel-releasing intrauterine device, LNG-IUD
9. Copper-bearing intrauterine device, Cu-IUD
Antiretroviral Medications and Abbreviations on the MEC Wheel
Nucleoside reverse
transcriptase inhibitors (NRTIs)
Non-nucleoside reverse
transcriptase inhibitors (NNRTIs) Protease inhibitors (PIs)
ABC Abacavir EFV Efavirenz ATV/r Ritonavir-boosted atazanavir
TDF Tenofovir ETR Etravirine LPV/r Ritonavir-boosted lopinavir
AZT Zidovudine NVP Nevirapine DRV/r Ritonavir-boosted darunavir
3TC Lamivudine RPV Rilpivirine RTV Ritonavir
DDI Didanosine
FTC Emtricitabine Integrase Inhibitors
D4T Stavudine RAL Raltegravir
Copper IUD for Emergency Contraception
This method is highly effective for preventing pregnancy.
It can be used within 5 days of unprotected intercourse
as an emergency contraceptive. However, when the time
of ovulation can be estimated, the Cu-IUD can be inserted
beyond 5 days after intercourse, if necessary, as long
as the insertion does not occur more than 5 days after
ovulation.
The eligibility criteria for general Cu-IUD insertion
also apply for the insertion of Cu-IUDs as emergency
contraception.
CONDITION Cu-IUD
Pregnancy 4
Rape
a) High risk of STI 3
b) Low risk of STI 1
a Breastfeeding is not recommended for one week after taking UPA since it is excreted in breast milk. Breast milk should be
expressed and discarded during that time
b ECPs may be less effective among women with BMI ≥ 30 kg/m2 than among women with BMI < 25 kg/m2. Despite this, there
are no safety concerns.
c Strong CYP3A4 inducers may reduce the effectiveness of emergency contraceptive pills.
d Repeated ECP use is an indication that the woman requires further counselling on other contraceptive options. Frequently
repeated ECP use may be harmful for women with conditions classified as 2, 3 or 4 for contraceptives containing hormones.
Abbreviations:
NA = not applicable; COC = combined oral contraceptives;
Cu-IUD = Copper intrauterine device;
ECP = emergency contraceptive pill;
LNG = levonorgestrel; UPA = ulipristal acetate
Emergency contraceptive pills
CONDITION COC LNG UPA
Pregnancy NA NA NA
Breastfeedinga 1 1 2
Past ectopic pregnancy 1 1 1
Obesityb (BMI ≥30 kg/m2
) 1 1 1
History of severe cardiovascular
disease (ischaemic heart disease,
cerebrovascular attack, or other
thromboembolic conditions)
2 2 2
Migraine 2 2 2
Severe liver disease (including
jaundice)
2 2 2
CYP3A4 inducersc
(e.g. rifampicin, phenytoin,
phenobarbital, carbamazepine,
efavirenz, fosphenytoin,
nevirapine, oxcarbazepine,
primidone, rifabutin, St John’s
wort/hypericum perforatum)
1 1 1
Repeated emergency
contraceptive pill used
1 1 1
Rape 1 1 1
Acknowledgements
The Medical Eligibility Criteria for Contraceptive Use and this version of
the Medical Eligibility Criteria Wheel were developed by the Word Health
Organization’s Department of Reproductive Health and Research. This
wheel is based upon similar medical eligibility criteria wheels developed
independently in Ghana and Jordan. In particular, we would like to thank
the University of Ghana Medical School’s Department of Obstetrics
and Gynaecology; the Communication Partnership for Family Health
in Jordan; and the Johns Hopkins Bloomberg School of Public Health/
Center for Communications Programs for their innovative work.
Dr Anna Altshuler was responsible for this 2015 edition, in collaboration
with Dr Erin Berry-Bibee, Dr Kathryn Curtis, Dr Monica Dragoman,
Dr Mary Lyn Gaffield, Dr Tara Jatlaoui, and Ms Halley Riley.
Layout and design: Ms Cath Hamill
Ordering copies and further information
Detailed information on the medical eligibility criteria, including
guidance on other contraceptive methods, appears in the Medical
Eligibility Criteria for Contraceptive Use, 5th edition (2015). This can be
accessed at http://www.who.int/reproductivehealth/en/. Bulk orders
(20 wheels/package) to supply programmes or single orders can be
ordered from: WHO Press, World Health Organization, 1211 Geneva 27,
Switzerland, email: bookorders@who.int. Order online: http://apps.who.
int/bookorders/

MEC-Wheel.pdfbbbhshshshshshshshshshshswgwwwhwhwhwhwh

  • 1.
    c o n t r o l l e d f a c t o r s N d i s e a s e i m m o b i l i z a i o n w i t h a u r a S m i g r a n o u s > 3 0 k g / m 2 o r a d e q u a t e l y r i s k h e a r t w i t h p r o l o n g e d a c u t e / fl a r e t u m o u r I t r e a t m e n t M i g r a i n e N o n - A g e > 3 5 A g e < 3 5 C u r r e n t B M I > 1 6 0 / > 1 0 0 1 4 0 - 1 5 9 / 9 0 - 9 9 M u l t i p l eI s c h a e m i c S t r o k e M a j o r s u r g e r y A c u t e H i s t o r y H e p a t i t i s L i v e r C u r r e n t P r e - 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 4 A 1 2 M 1 1 1 2 1 2 1 2 2 M 2 2 3 L 2 1 3 4 4 A 2 2 M 1 1 1 2 1 2 1 2 2 M 2 M 2 3 L 2 1 3 4 2 1 - 2 M 1 1 1 2 Q 1 P 3 2 3 3 3 2 3 L 2 1 3 4 2 2 M , S 1 1 1 2 1 2 1 2 2 M 2 M 2 3 L 2 1 3 4 1 4 S 1 3 R 2 2 Q 2 4 3 3 / 4 4 4 4 4 4 3 / 4 K , A 4 J 4 2 D I S E A S E C A N C E R C A N C E R H E A D A C H E S M O K I N G D I A B E T E S Q O B E S I T Y H Y P E R T E N S I O N O C A R D I O V A S C U L A R V E N O U S T H R O M B O E M B O L I S M L I V E R D I S E A S E S B R E A S T C E R V I C A L How to use this wheel The wheel matches up the contraceptive methods, shown on the inner disk, with specific medical conditions or characteristics shown around the outer rim. The numbers shown in the viewing slot tell you whether the woman who has this known condition or characteristic is able to start use of the contraceptive method: CATEGORY WITH CLINICAL JUDGEMENT WITH LIMITED CLINICAL JUDGEMENT 1 Use method in any circumstance YES (Use the method) 2 Generally use method 3 Use of method not usually recommended unless other more appropriate methods are not available or not acceptable NO (Do not use the method) 4 Method not to be used Categories 1 and 4 are clearly defined recommendations. For categories 2 or 3, greater clinical judgement will be needed and careful follow-up may be required. If clinical judgement is limited, categories 1 and 2 both mean the method can be used, and categories 3 and 4 both mean the method should not be used. No restrictions for some conditions: there are many medical conditions when ALL methods can be used (that is, all the methods are either a category 1 or 2). Some of these conditions are listed on the back of the wheel. With few exceptions, all women can safely use emergency contraception, barrier and behavioural methods of contraception, including lactational amenorrhoea method; for the complete list of recommendations, please see the full document. Only correct and consistent use of condoms, male or female, protect against STI/HIV. If there is a risk of STI/HIV, condom use is recommended. MEDICAL ELIGIBILITY CRITERIA WHEEL FOR CONTRACEPTIVE USE WHO 2015 c o n v u l s a n t s T < 1 8 y e a r s abortion STIs vaginitis S t a g e 3 o r 4 t h e r a p y R i f a b u t i n a n t i - t o a g e <6 months <6 weeks <4 weeks and post- risk of and C h l a m ydia A n t i r e t r o v i r a l R i f a m p i c i n / C e r t a i n U n e x p l a i n e d M e n a r c h e 6 weeks to 4 weeks to 48 hours to <48 hours Puerperal Current Increased Other STIs G o n o r rhoea W H O N E O P L A S I A F I B R O I D S B L E E D I N G INFECTIONS INFECTIONS INFECTIONS S EXUALLY TRANSMITTED M E D I C A T I O N S C E R V I C A L U T E R I N E V A G I N A L A D O L E S C E N T S NULLI P A R I T Y POSTPARTUM AND BREASTFEEDING SEPSIS P I DC H I V Progestogen-only pills 2 POP P r o g e stin-only injectables 3 DMPA (IM, SC) / N E T - E N L e v o n orgestrel IUD 2E LNG-IUD C o pper IUD 1 Cu-IUD Implants 2 LNG / ETG C o m b i n e d hormonal contraceptives 4D Pill, patch, ring, injec t a b l e ( C O C , P , C V R , C I C ) ISBN 978 92 4 154925 7 WHO Library Cataloguing-in-Publication Data WHO medical eligibility criteria wheel for contraceptive use – 2015 update. 1.Contraception - methods. 2.Family Planning Services - methods. 3.Eligibility Determination - standards. I.World Health Organization. ISBN 978 92 4 154925 7 (NLM classification: WP 630) © World Health Organization 2015 All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution– should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index.html). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Printed in Italy MEDICAL ELIGIBILITY CRITERIA WHEEL FOR CONTRACEPTIVE USE WHO 2015 c o n v u l s a n t s T < 1 8 y e a r s abortion STIs vaginitis S t a g e 3 o r 4 t h e r a p y R i f a b u t i n a n t i - t o a g e <6 months <6 weeks <4 weeks and post- risk of and C h l a m ydia A n t i r e t r o v i r a l R i f a m p i c i n / C e r t a i n U n e x p l a i n e d M e n a r c h e 6 weeks to 4 weeks to 48 hours to <48 hours Puerperal Current Increased Other STIs G o n o r rhoea W H O N E O P L A S I A F I B R O I D S B L E E D I N G INFECTIONS INFECTIONS INFECTIONS S EXUALLY TRANSMITTED M E D I C A T I O N S C E R V I C A L U T E R I N E V A G I N A L A D O L E S C E N T S NULLI P A R I T Y POSTPARTUM AND BREASTFEEDING SEPSIS P I DC H I V Progestogen-only pills 2 POP P r o g e stin-only injectables 3 DMPA (IM, SC) / N E T - E N L e v o n orgestrel IUD 2E LNG-IUD C o pper IUD 1 Cu-IUD Implants 2 LNG / ETG C o m b i n e d hormonal contraceptives 4D Pill, patch, ring, injec t a b l e ( C O C , P , C V R , C I C ) ISBN 978 92 4 154925 7 WHO Library Cataloguing-in-Publication Data WHO medical eligibility criteria wheel for contraceptive use – 2015 update. 1.Contraception - methods. 2.Family Planning Services - methods. 3.Eligibility Determination - standards. I.World Health Organization. ISBN 978 92 4 154925 7 (NLM classification: WP 630) © World Health Organization 2015 All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce or translate WHO publications –whether for sale or for non-commercial distribution– should be addressed to WHO Press through the WHO website (www.who.int/about/licensing/copyright_form/en/index.html). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Printed in Italy
  • 2.
    Use the methodin any circumstance Use of the method not usually recommended unless other, more appropriate methods are not available or acceptable 1 Generally use the method 2 3 4 Method NOT to be used WHO Medical Eligibility Criteria Wheel for contraceptive use, 2015 These methods do not protect against STI/HIV. If there is a risk of STI/HIV, the correct and consistent use of condoms, male or female, is recommended. C o m b i n e d h ormonal contraceptives Pill, patch, ring, injectab l e ( C O C , P , C V R , C I C ) P rogestogen-only pills POP P r o g e s t o g en-only injectables DMPA (IM, SC) / N E T - E N L e v o n o rgestrel IUD LNG-IUD C o pper IUD Cu-IUD Implants LNG / ETG
  • 3.
    c o n v u l s a n t s T c o n t r o ll e d f a c t o r s N d i s e a s e i m m o b i l i z a i o n < 1 8 y e a r s abortion STIs vaginitis S t a g e 3 o r 4 t h e r a p y R i f a b u t i n a n t i - w i t h a u r a S m i g r a n o u s > 3 0 k g / m 2 o r a d e q u a t e l y r i s k h e a r t w i t h p r o l o n g e d a c u t e / fl a r e t u m o u r I t r e a t m e n t t o a g e <6 months <6weeks <4 weeks and post- risk of and C h l a m ydia A n t i r e t r o v i r a l R i f a m p i c i n / C e r t a i n M i g r a i n e N o n - A g e > 3 5 A g e < 3 5 C u r r e n t B M I > 1 6 0 / > 1 0 0 1 4 0 - 1 5 9 /9 0 - 9 9 M u l t i p l e I s c h a e m i c S t r o k e M a j o r s u r g e r y A c u t e H i s t o r y H e p a t i t i s L i v e r C u r r e n t P r e - U n e x p l a i n e d M e n a r c h e 6 weeks to 4 weeks to 48 hours to <48 hours Puerperal Current Increased Other STIs G o n o rrhoea W H O 2 4 A 3 A 2 / 3 A Z 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 4 A 1 1 H 4 A 2 2 1 1 3 1 4 4A 2/3B 2 4 A 3 A 2 / 3 A Z 1 1 2 M 1 1 1 2 1 2 1 2 2 M 2 2 3 L 2 1 3 4 4 A 2 1 H 4 A 2 2 1 1 3 2E 4 4A 2/3B 1 1 1 - 2 Y 2 2 V 2 M 1 1 1 2 1 2 1 2 2 M 2 M 2 3 L 2 1 3 4 2 2 1 3 1 1 1 2 2 2 1 1 1 1 1 1 1 - 2 Y 1 - 2 W 1- 2 W,V 2 M 1 1 1 2 Q 1 P 3 2 3 3 3 2 3 L 2 1 3 4 2 2 1 3 2 1 1 3 3 3 1 1 1 1 1 1 1 - 2 Y 3 3 V 2 M,S 1 1 1 2 1 2 1 2 2 M 2 M 2 3 L 2 1 3 4 1 1 1 2 1 1 1 2 2 2 1 1 1 1 1 1 1 - 2 Y 3 X 3 U 4 S 1 3 R 2 2 Q 2 4 3 3/ 4 4 4 4 4 4 3 / 4 K , A 4 J 4 2 2 1 2 1 1 3 G 4 F 4D,F 4D 1 1 1 1 D I S E A S E C A N C E R C A N C E R N E O P L A S I A F I B R O I D S B L E E D I N G INFECTIONS INFECTIONS INFECTIONS SEXUALLY TRANSMITTED M E D I C A T I O N S H E A D A C H E S M O K I N G D I A B E T E S Q O B E S I T Y H Y P E R T E N S I O N O C A R D I O V A S C U L A R V E N O U S T H R O M B O E M B O L I S M L I V E R D I S E A S E S B R E A S T C E R V I C A L C E R V I C A L U T E R I N E V A G I N A L A D O L E S C E N T S NULLI P A R I T Y POSTPARTUM AND BREASTFEEDING SEPSIS P I DC H I V
  • 4.
    Conditions that arecategory 1 and 2 for all methods (method can be used) Reproductive Conditions: Benign breast disease or undiagnosed mass • Benign ovarian tumours, including cysts • Dysmenorrhoea • Endometriosis • History of gestational diabetes • History of high blood pressure during pregnancy • History of pelvic surgery, including caesarean delivery • Irregular, heavy or prolonged menstrual bleeding (explained) • Past ectopic pregnancy • Past pelvic inflammatory disease • Post-abortion (no sepsis) • Postpartum ≥ 6 months Medical Conditions: Depression • Epilepsy • HIV asymptomatic or mild clinical disease (WHO Stage 1 or 2) • Iron-deficiency anaemia, sickle-cell disease and thalassaemia • Malaria • Mild cirrhosis • Schistosomiasis (bilharzia) • Superficial venous disorders, including varicose veins • Thyroid disorders • Tuberculosis (non-pelvic) • Uncomplicated valvular heart disease • Viral hepatitis (carrier or chronic) Other: Adolescents • Breast cancer family history • Venous thromboembolism (VTE) family history • High risk for HIV • Surgery without prolonged immobilization • Taking antibiotics (excluding rifampicin/rifabutin) With few exceptions, all women can safely use emergency contraception, barrier and behavioural methods of contraception, including lactational amenorrhoea method; for the complete list of recommendations, please see the full document. “Combined” is a combination of ethinyl estradiol & a progestogen. CIC: combined injectable contraceptive COC: combined oral contraceptive pill Cu-IUD: copper intrauterine device CVR: combined contraceptive vaginal ring DMPA (IM, SC): depot medroxyprogesterone acetate, intramuscular or subcutaneous ETG: etonogestrel LNG: levonorgestrel LNG-IUD: levonorgestrel intrauterine device NET-EN: norethisterone enanthate P: combined contraceptive patch POP: progestogen-only pill A If condition develops while using method, can continue using it during treatment. B If very high likelihood of exposure to gonorrhoea or chlamydia =3. C If past pelvic inflammatory disease (PID) all methods =1, including IUDs. D If <3 wks, not breastfeeding & no other VTE risk factors =3. E If not breastfeeding =1. R If <15 cigarettes/day CIC =2. If ≥15 cigarettes/day COC/P/CVR =4. S Aura is focal neurological symptoms, such as flickering lights. If no aura & age <35 COC/P/CVR, CIC =2, POP =1. If no aura & age ≥35 COC/P/CVR, CIC =3, POP =1. T Barbituates, carbamazepine, oxcarbazepine, phenytoin, primidone, topiramate & lamotrigine. U If barbituates, carbamazepine, oxcarbazepine, phenytoin, primidone or topiramate CIC =2. V If lamotrigine =1. W DMPA =1, NET-EN =2. X CICs =2. Y If antiretroviral therapy with EFV, NVP, ATV/r, LPV/r, DRV/r, RTV: COC/P/CVR, CIC, POP, NET-ET, Implants =2; DMPA =1. For all NRTIs, ETR, RPV, RAL each method =1. See jacket for full names of medications. Z If WHO Stage 3 or 4 (severe or advanced HIV clinical disease) IUD =3. G If ≥6 wks & not breastfeeding =1. H If uterine cavity distorted preventing insertion =4. I Refers to hepatocellular adenoma (benign) or carcinoma/ hepatoma (malignant). J If adenoma CIC =3, if carcinoma/hepatoma CIC =3/4. K CIC =3. L If established on anticoagulation therapy =2. M If condition developed while on this method, consider switching to non-hormonal method. N Risk factors: older age, smoking, diabetes, hypertension, obesity & known dyslipidaemias. O If cannot measure blood pressure & no known history of hypertension, can use all methods. Either systolic or diastolic blood pressure may be elevated. P If age <18 yrs & obese DMPA/NET-EN =2. Q For insulin-dependent & non-insulin-dependent. If complicated or >20 yrs duration, COC/P/CVR, CIC =3/4; DMPA, NET-EN =3. F If 3 to <6 wks, not breastfeeding & no other VTE risk factors =2, with other VTE risk factors =3.
  • 5.
    About this wheel Thiswheel contains the medical eligibility criteria for starting use of contraceptive methods, based on Medical Eligibility Criteria for Contraceptive Use, 5th edition (2015), one of WHO’s evidence-based guidelines. It guides family planning providers in recommending safe and effective contraception methods for women with medical conditions or medically-relevant characteristics. The wheel includes recommendations on initiating use of nine common types of contraceptive methods: 1. Combined pills, COC (low dose combined oral contraceptives, with ≤ 35 μg ethinyl estradiol) 2. Combined contraceptive patch, P 3. Combined contraceptive vaginal ring, CVR 4. Combined injectable contraceptives, CIC 5. Progestogen-only pills, POP 6. Progestogen-only injectables, DMPA (IM,SC)/NET-EN (depot medroxyprogesterone acetate intramuscular or subcutaneous or norethisterone enantate intramuscular) 7. Progestogen-only implants, LNG/ETG (levonorgestrel or etonogestrel) 8. Levonorgestrel-releasing intrauterine device, LNG-IUD 9. Copper-bearing intrauterine device, Cu-IUD Antiretroviral Medications and Abbreviations on the MEC Wheel Nucleoside reverse transcriptase inhibitors (NRTIs) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Protease inhibitors (PIs) ABC Abacavir EFV Efavirenz ATV/r Ritonavir-boosted atazanavir TDF Tenofovir ETR Etravirine LPV/r Ritonavir-boosted lopinavir AZT Zidovudine NVP Nevirapine DRV/r Ritonavir-boosted darunavir 3TC Lamivudine RPV Rilpivirine RTV Ritonavir DDI Didanosine FTC Emtricitabine Integrase Inhibitors D4T Stavudine RAL Raltegravir Copper IUD for Emergency Contraception This method is highly effective for preventing pregnancy. It can be used within 5 days of unprotected intercourse as an emergency contraceptive. However, when the time of ovulation can be estimated, the Cu-IUD can be inserted beyond 5 days after intercourse, if necessary, as long as the insertion does not occur more than 5 days after ovulation. The eligibility criteria for general Cu-IUD insertion also apply for the insertion of Cu-IUDs as emergency contraception. CONDITION Cu-IUD Pregnancy 4 Rape a) High risk of STI 3 b) Low risk of STI 1 a Breastfeeding is not recommended for one week after taking UPA since it is excreted in breast milk. Breast milk should be expressed and discarded during that time b ECPs may be less effective among women with BMI ≥ 30 kg/m2 than among women with BMI < 25 kg/m2. Despite this, there are no safety concerns. c Strong CYP3A4 inducers may reduce the effectiveness of emergency contraceptive pills. d Repeated ECP use is an indication that the woman requires further counselling on other contraceptive options. Frequently repeated ECP use may be harmful for women with conditions classified as 2, 3 or 4 for contraceptives containing hormones. Abbreviations: NA = not applicable; COC = combined oral contraceptives; Cu-IUD = Copper intrauterine device; ECP = emergency contraceptive pill; LNG = levonorgestrel; UPA = ulipristal acetate Emergency contraceptive pills CONDITION COC LNG UPA Pregnancy NA NA NA Breastfeedinga 1 1 2 Past ectopic pregnancy 1 1 1 Obesityb (BMI ≥30 kg/m2 ) 1 1 1 History of severe cardiovascular disease (ischaemic heart disease, cerebrovascular attack, or other thromboembolic conditions) 2 2 2 Migraine 2 2 2 Severe liver disease (including jaundice) 2 2 2 CYP3A4 inducersc (e.g. rifampicin, phenytoin, phenobarbital, carbamazepine, efavirenz, fosphenytoin, nevirapine, oxcarbazepine, primidone, rifabutin, St John’s wort/hypericum perforatum) 1 1 1 Repeated emergency contraceptive pill used 1 1 1 Rape 1 1 1 Acknowledgements The Medical Eligibility Criteria for Contraceptive Use and this version of the Medical Eligibility Criteria Wheel were developed by the Word Health Organization’s Department of Reproductive Health and Research. This wheel is based upon similar medical eligibility criteria wheels developed independently in Ghana and Jordan. In particular, we would like to thank the University of Ghana Medical School’s Department of Obstetrics and Gynaecology; the Communication Partnership for Family Health in Jordan; and the Johns Hopkins Bloomberg School of Public Health/ Center for Communications Programs for their innovative work. Dr Anna Altshuler was responsible for this 2015 edition, in collaboration with Dr Erin Berry-Bibee, Dr Kathryn Curtis, Dr Monica Dragoman, Dr Mary Lyn Gaffield, Dr Tara Jatlaoui, and Ms Halley Riley. Layout and design: Ms Cath Hamill Ordering copies and further information Detailed information on the medical eligibility criteria, including guidance on other contraceptive methods, appears in the Medical Eligibility Criteria for Contraceptive Use, 5th edition (2015). This can be accessed at http://www.who.int/reproductivehealth/en/. Bulk orders (20 wheels/package) to supply programmes or single orders can be ordered from: WHO Press, World Health Organization, 1211 Geneva 27, Switzerland, email: bookorders@who.int. Order online: http://apps.who. int/bookorders/