This document discusses direct-to-consumer advertising of pharmaceutical drugs in the United States. It notes that spending on prescription drug advertising in the US increased from $1 billion in 1998 to $2.8 billion in 2002. The first direct-to-consumer print ad was for Merck's pneumonia vaccine in 1981, while the first TV ad was for an ibuprofen brand in Florida in 1983. Supporters argue that such advertising helps educate people and increase drug compliance, while critics argue it can lead to overprescription and use of minimally effective drugs. The document also discusses lifestyle diseases and drugs.