Mangalyaan
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Mangalyaan carried five scientific payloads to study Mars' surface features, morphology, mineralogy and atmosphere as well as Mars' surface temperature. These payloads included a Methane Sensor for Mars (MSM) to detect methane in Mars' atmosphere, a Lyman Alpha Photometer (LAP) to measure deuterium to hydrogen ratio to understand water loss on Mars, a Mars Exospheric Neutral Composition Analyser (MENCA) to measure the composition and variability of neutral gases in the Martian exosphere, a Thermal Infrared Imaging Spectrometer (TIS) to study Mars' surface mineralogy and thermophysical features, and a Mars Color Camera (MCC) to image surface features and
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Mangalyaan
It is the power point presentation about Mangalyaan. It contains slide about Mars, Mangalyaan and ISRO.
Recommended
Mangalyaan
It is the power point presentation about Mangalyaan. It contains slide about Mars, Mangalyaan and ISRO.
Dennis yu social amplification engine_guide_v5.1_2016_1210
Advanced Social Media Advertising & Content Marketing
Building and Managing Social Media Collections
Presenters:
Laura Wrubel
Jason Casden
Presented at DLF Forum 2015 on October 27th, 2015.
As venues for discourse and creation, social media platforms such as Twitter and Instagram are important source material for scholarly research. Future access to social media data will allow researchers to develop historical assessments based on materials representing the voices of a large and diverse set of participants. Much of this critical and ephemeral content may be lost if cultural heritage institutions are not collecting and preserving it, yet creating and managing these collections presents challenges around collecting mechanisms, curation, legal and ethical issues, and preservation.
This workshop will include the following components:
• A review of technical tools for collecting and guidelines for selecting an approach that works best for your institution and users
• A guided discussion of ethical and legal considerations in taking on this work and parallels with established archival practices
• A review of some existing use cases of libraries' social media data collecting followed by a group discussion of possible community-specific use cases and needs for supporting services.
• A demonstration of possible archival collecting workflows using NCSU Libraries' Social Media Combine collecting system (which includes NCSU Libraries' lentil system for Instagram harvesting and George Washington University's Social Feed Manager for Twitter harvesting). Participants who wish to follow along with their own instance may install it ahead of time.
Participants will leave with an awareness of the major components of a new social media collecting program, including available tools, research use cases, ethical and legal considerations, supporting resources, as well as a better understanding of how to integrate social media into existing practices and workflows. There will be opportunities to share collecting ideas with each other at the end of the workshop.
Forgive and forget
Thoughts such as, what does forgive and forget mean, what it is all about and what its different facets are, may enable the facilitator understand it better. Some such thoughts about forgive and forget are given below.)
1. Forgiveness (in our daily life) is a practice to pardon without any conditions or expectations.
INTENT
(The objective of the facilitation process is to help each participant explore the topic for himself, individually and independently. Following are some of the objectives of the session.)
1. To understand what is forgiveness
2. To analyse whether forgiveness plays a role in one’s life
3. To explore whether forgiving impacts oneself, people around, situations, outcomes
QUESTIONS
(These are some leading questions that the facilitator may contemplate on for understanding and connecting with the topic.)
1. What is forgiving?
2. Does forgiveness plays a role in one’s life? If yes, how?
3. Does forgiving impacts oneself? If yes, how?
4. Does forgiving impacts people around? If yes, how?
5. Does forgiving impacts situations? If yes, how?
6. Does forgiving impacts outcome? If yes, how
Marketing management of mushroom and 7 p’s A Presentation By Mr Allah Dad k...
Marketing management of mushroom and 7 p’s A Presentation By Mr Allah Dad khan Former Director General Agriculture Extension KPK Province and Visiting Professor the University of Agriculture Peshawar
Mangalyaan - India's First Interplanetary Mission to Mars
A Technical Overview of India's First Interplanetary Mission to Mars - Mangalyaan Orbiter
MANGALYAAN
INDIA'S FIRST MARS SPACE MISSION NAMED MARS ORBITER MISSION(MOM) SIMPLY KNOWN AS MANGALYAN. FOR MORE UPDATES AND SLIDES VISIT www.mechanizeinn.wordpress.com OR www.facebook.com/mechanizeinn
India's Mission to Mars
INDIA'S MARS MISSION - ONE OF THE MOST ECONOMICAL INTERPLANETARY MISSIONS EVER UNDERTAKEN
RNA INTERFERENCE: UNRAVELING GENETIC SILENCING
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's entangled aventures in wonderland
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Orion Air Quality Monitoring Systems - CWS
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
4. An Overview of Sugarcane White Leaf Disease in Vietnam.pdf
An overview of Sugarcane White Leaf Disease in Vietnam
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/More Related Content
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Dennis yu social amplification engine_guide_v5.1_2016_1210
Advanced Social Media Advertising & Content Marketing
Building and Managing Social Media Collections
Presenters:
Laura Wrubel
Jason Casden
Presented at DLF Forum 2015 on October 27th, 2015.
As venues for discourse and creation, social media platforms such as Twitter and Instagram are important source material for scholarly research. Future access to social media data will allow researchers to develop historical assessments based on materials representing the voices of a large and diverse set of participants. Much of this critical and ephemeral content may be lost if cultural heritage institutions are not collecting and preserving it, yet creating and managing these collections presents challenges around collecting mechanisms, curation, legal and ethical issues, and preservation.
This workshop will include the following components:
• A review of technical tools for collecting and guidelines for selecting an approach that works best for your institution and users
• A guided discussion of ethical and legal considerations in taking on this work and parallels with established archival practices
• A review of some existing use cases of libraries' social media data collecting followed by a group discussion of possible community-specific use cases and needs for supporting services.
• A demonstration of possible archival collecting workflows using NCSU Libraries' Social Media Combine collecting system (which includes NCSU Libraries' lentil system for Instagram harvesting and George Washington University's Social Feed Manager for Twitter harvesting). Participants who wish to follow along with their own instance may install it ahead of time.
Participants will leave with an awareness of the major components of a new social media collecting program, including available tools, research use cases, ethical and legal considerations, supporting resources, as well as a better understanding of how to integrate social media into existing practices and workflows. There will be opportunities to share collecting ideas with each other at the end of the workshop.
Forgive and forget
Thoughts such as, what does forgive and forget mean, what it is all about and what its different facets are, may enable the facilitator understand it better. Some such thoughts about forgive and forget are given below.)
1. Forgiveness (in our daily life) is a practice to pardon without any conditions or expectations.
INTENT
(The objective of the facilitation process is to help each participant explore the topic for himself, individually and independently. Following are some of the objectives of the session.)
1. To understand what is forgiveness
2. To analyse whether forgiveness plays a role in one’s life
3. To explore whether forgiving impacts oneself, people around, situations, outcomes
QUESTIONS
(These are some leading questions that the facilitator may contemplate on for understanding and connecting with the topic.)
1. What is forgiving?
2. Does forgiveness plays a role in one’s life? If yes, how?
3. Does forgiving impacts oneself? If yes, how?
4. Does forgiving impacts people around? If yes, how?
5. Does forgiving impacts situations? If yes, how?
6. Does forgiving impacts outcome? If yes, how
Marketing management of mushroom and 7 p’s A Presentation By Mr Allah Dad k...
Marketing management of mushroom and 7 p’s A Presentation By Mr Allah Dad khan Former Director General Agriculture Extension KPK Province and Visiting Professor the University of Agriculture Peshawar
Mangalyaan - India's First Interplanetary Mission to Mars
A Technical Overview of India's First Interplanetary Mission to Mars - Mangalyaan Orbiter
MANGALYAAN
INDIA'S FIRST MARS SPACE MISSION NAMED MARS ORBITER MISSION(MOM) SIMPLY KNOWN AS MANGALYAN. FOR MORE UPDATES AND SLIDES VISIT www.mechanizeinn.wordpress.com OR www.facebook.com/mechanizeinn
India's Mission to Mars
INDIA'S MARS MISSION - ONE OF THE MOST ECONOMICAL INTERPLANETARY MISSIONS EVER UNDERTAKEN
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Recently uploaded
RNA INTERFERENCE: UNRAVELING GENETIC SILENCING
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's entangled aventures in wonderland
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Orion Air Quality Monitoring Systems - CWS
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
4. An Overview of Sugarcane White Leaf Disease in Vietnam.pdf
An overview of Sugarcane White Leaf Disease in Vietnam
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...
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Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/Cancer cell metabolism: special Reference to Lactate Pathway
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's aventures in two entangled wonderlands
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
SCHIZOPHRENIA Disorder/ Brain Disorder.pdf
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
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Mangalyaan
- 3. Mangalyaan
Editor's Notes
- Dr. Vikram Sarabhai-The father of Indian Space Programme Chairman-Dr K. Radhakrishnan