Check out the fourth part of our series presentation on 'Acne' named "Management of Acne (Part-3)" and provide your valuable feedback.

1. Manuscriptedit
Management of Acne – 5
where do we stand ?
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2. Treatment challenges
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Acne venenata
Nodulocystic acne
Acne fulminans
Acne conglobata
Predominant closed comedones
Nodular lesion
Cysts of acne

3. • Preventing Early Acne Scars

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Dermaplaning (before peeling)
Chemical Peels
Intense Pulsed Light (IPL)
Skin Lifting

6. Feature Challenges
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Life style -( look concern )
Acne Venenata (cosmetics, environmental)
Drug resistance

7. How can one class of drugs have such a wide
range of seemingly unrelated activities?

8. The clinical spectrum of retinoids

9. Retinoids available
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Tretinoin
Adapalene
Tazarotene
Alitretinoin
Bexarotene

10. Topical Agents available for Acne
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Tretinoin
Adapalene
Tazarotene
Isotretinoin
Motretinide
Retinaldehyde
Retinoyl –beta glucuronide

11. Topical retinoids in Acne
Topical Retinoids Have Multiple Anti-Acne Actions
– Inhibit the formation and reduce the number of microcomedo
– Reduce mature comedones
– Reduce inflammatory lesions
– Promote normal desquamation of follicular epithelium
– Anti-inflammatory action
– Likely to enhance penetration of other drugs
– Likely to maintain remission of acne by inhibiting
microcomedo formation, thus preventing new lesions

12. “In dermatology, retinoids are the most exciting and important
pharmacological agents in light of their large presence on the
therapeutic scene. If no more retinoids were added to the
inventory, clinicians would still be busy for decades, searching
for a new therapeutic applications in diverse areas of clinical
medicine”
- Dr. Albert M. Kligman, Philadelphia
August 1998

13. Introduction
• It is a common inflammatory condition of
pilosebaceous unit
• 90% of adolescent suffer from it during their life time
• Cause is multifactorial- abnormal keratinization,
P.acnes, genetics, hormones, environment
• It produces wide variants acne
• Many topical and oral medications are effective, but
selection of appropriate medication /procedure is
effective

14. Management of Acne
THANK YOU

15. VISIT
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