The document contains data from multiple studies comparing different wound dressings and skin treatments: - A graph shows that a NEOSALUSTM dressing reduced wound area more than two other dressings over 10 days. - A table shows that NEOSALUSTM and another dressing had lower inflammation scores than a third dressing at several time points over 14 days. - A graph demonstrates that a skin protectant reduced irritation from sodium lauryl sulfate compared to an untreated control over 10 days. - Two charts indicate that a skin-protective foam reduced corticosteroid use and improved symptoms in patients with chronic hand dermatitis compared to a moisturizer alone. - Additional data and

1. Average Wound Area
800.0
700.0
600.0
500.0
400.0
300.0
200.0
100.0
0.0
-100.0
Days Post Injury
4 7 10
WoundArea(mm2)
NEOSALUS™
Johnson & Johnson Dressing
Biafine®*
* Biafine is a registered trademark of Ortho Dermatologics

2. Time Point (Days Post Injury)
TotalInflammationScore
Score is an aggregate of edema, erythema, exudate.
22
7
Signs of Inflammation*
* Biafine is a registered trademark of Ortho Dermatologics
1 4 10 14
20
18
16
14
12
10
8
6
4
2
0
NEOSALUS™
Johnson & Johnson Dressing
Biafine®*

3. Prevention of Sodium Lauryl Sulfate
Irristant Contact Dermatitis by Proderm
from Skin Protectant6
6
Days
N=20
5
4
3
2
1
0
0 1 2 3 4 5 6 7 8 9 10
Untreated Treated with Proderm
MeanIrritancyScore

4. 60%
50%
40%
30%
20%
10%
0
37%
10%
53%
Stopped Using or
Reduced Corticosteroid
Use
Corticosteroid Use Compared to Baseline
No Change in
Corticosteroid Use
Increased
Corticosteroid Use
n=31
Efficacy of a Skin-Protective Foam in the
Treatment of Chronic Hand Dermatitis
PercentageofSubjects

5. Efficacy of NEOSALUS™ Foam in
Subjects Diagnosed with Chronic Hand
Dermatitis
5
Overall Improvement in Investigator Global Assessment Score
Baseline Final
n=40
4
3
2
1
0
Group A Group B
2.73 2.94
n=22 n=18
Weeks 1-2
1.82
n=22
2.30
n=18
Weeks 3-8
NEOSALUS™
FOAM (TID) +
Triamcinolone
Cream 0.1 % (TID)
P=0.1442; one sided t-test
Cetaphil®
Moisturizer(TID) +
Triamcinolone
Cream 0.1 % (TID)
NEOSALUS™
FOAM (TID) +
Triamcinolone
Cream 0.1 % (PRN)
Cetaphil®
Moisturizer(TID) +
Triamcinolone
Cream 0.1 % (PRN)
P=0.0318; one sided t-test
Group A
Group B
MeanIGAScore

6. 50
Group A
Group B
9
30
n=20
n=15
Triamcinolone
Cream 0.1 %
Triamcinolone
Cream 0.1 %
P=0.0359; one sided t-test
40
30
20
10
0
MeanTotalofApplications

7. 75
Untreated
Day 0
Treated with Proderm Technology®
70
65
60
55
50
45
Day 10 Day 21
n=24
HydrationPercentage