A 9 year old female presented to the emergency department after falling from a horse at summer camp. She reported pain in her right wrist with palpation and motion. Examination revealed mild swelling and tenderness over the right wrist, but no obvious fractures on x-ray. Due to concern for a possible Salter Harris I fracture that may not be visible on initial films, the patient was splinted and advised to follow up with orthopedics for repeat x-rays in 7-10 days.
This document contains multiple word problems about tides, water depth, and trigonometric functions. It asks the reader to graph functions, write equations, and determine values based on given information about tides, water depth, times of high and low tides, and other tidal data. It provides context, equations, and questions to help the reader practice skills involving graphing, writing equations, and solving problems related to tidal patterns and sinusoidal functions.
This document provides sizing information for an arch support insole model QS7001. It lists the available female sizes from 9.0/10.5 to 5.0/6.0 and male sizes from 10.5/12.0 to 5.0/6.0. The insole is designed to provide cushioning and support for the feet.
A 9 year old female presented to the emergency department after falling from a horse at summer camp. She reported pain in her right wrist with palpation and motion. Examination revealed mild swelling and tenderness over the right wrist, but no obvious fractures on x-ray. Due to concern for a possible Salter Harris I fracture that may not be visible on initial films, the patient was splinted and advised to follow up with orthopedics for repeat x-rays in 7-10 days.
This document contains multiple word problems about tides, water depth, and trigonometric functions. It asks the reader to graph functions, write equations, and determine values based on given information about tides, water depth, times of high and low tides, and other tidal data. It provides context, equations, and questions to help the reader practice skills involving graphing, writing equations, and solving problems related to tidal patterns and sinusoidal functions.
This document provides sizing information for an arch support insole model QS7001. It lists the available female sizes from 9.0/10.5 to 5.0/6.0 and male sizes from 10.5/12.0 to 5.0/6.0. The insole is designed to provide cushioning and support for the feet.
The document summarizes a study that investigated the effects of iron supplementation alone and in combination with vitamins on hematological status, oxidative stress, and erythrocyte membrane fluidity in anemic pregnant women. 164 anemic pregnant women were randomly assigned to receive placebo, iron alone, iron with folic acid, or iron with folic acid, retinol, and riboflavin for 2 months. The study found that supplementation significantly increased hemoglobin and ferritin levels and decreased oxidative stress markers in all treatment groups compared to placebo. Erythrocyte membrane fluidity also increased with supplementation.
Mitochondrial dysfunction and oxidative damage are thought to play a role in Parkinson's disease (PD) pathogenesis. Recent animal studies show that inhibiting mitochondrial complex I with rotenone closely mimics PD's biochemical and histological features. Several agents like creatine, coenzyme Q10, and acetyl-L-carnitine have shown benefits in animal models by modulating energy metabolism and reducing oxidative stress. These agents warrant further study as potential neuroprotective treatments for PD.
La conduzione del nervo surale dorsale in pazienti con carenza di vitamina B1...MerqurioEditore_redazione
This study investigated peripheral neuropathy in vitamin B12 deficient patients with megaloblastic anemia using dorsal sural nerve conduction studies and tibial sensory-evoked potentials. Dorsal sural nerve responses were absent in over half of patients but only one third had abnormalities on conventional nerve conduction studies. Patients with recordable dorsal sural nerves had prolonged latencies, reduced amplitudes, and slower conduction velocities compared to controls, suggesting dorsal sural nerve conduction is more sensitive for detecting early neuropathy. Over 70% of patients showed evidence of myelopathy on tibial sensory-evoked potentials and neurological examination.
Utilità della misurazione dei livelli di vitamina B12 e della sua frazione at...MerqurioEditore_redazione
This study evaluated vitamin B12 (VitB12) and its active fraction, holotranscobalamin (holoTC), for detecting VitB12 deficiency in 1,279 patients with neurological conditions. Elevated methylmalonic acid (MMA) levels were used as the criterion for VitB12 deficiency. Among patients with normal renal function, 13.2% had VitB12 deficiency based on MMA levels. However, VitB12 and holoTC levels showed poor correlation with VitB12 deficiency. Neither VitB12 nor holoTC demonstrated superior diagnostic accuracy for detecting VitB12 deficiency compared to the other. The study concludes that neither VitB12 nor holoTC can be reliably used
Caratteristiche cliniche e di laboratorio e risposta al trattamento in pazien...MerqurioEditore_redazione
This study examined 63 patients presenting with vitamin B12 deficiency-related neurological syndromes. The most common neurological manifestation was myeloneuropathy, seen in 54% of patients. Neuropsychiatric symptoms including dementia were observed in 38% of patients. All patients showed megaloblastic changes in bone marrow smears. Treatment with parenteral vitamin B12 injections resulted in improvement in 54% of patients after 6 months of follow up. A normal hemoglobin or MCV level does not rule out vitamin B12 deficiency.
The document summarizes a study that investigated the effects of iron supplementation alone and in combination with vitamins on hematological status, oxidative stress, and erythrocyte membrane fluidity in anemic pregnant women. 164 anemic pregnant women were randomly assigned to receive placebo, iron alone, iron with folic acid, or iron with folic acid, retinol, and riboflavin for 2 months. The study found that supplementation significantly increased hemoglobin and ferritin levels and decreased oxidative stress markers in all treatment groups compared to placebo. Erythrocyte membrane fluidity also increased with supplementation.
Mitochondrial dysfunction and oxidative damage are thought to play a role in Parkinson's disease (PD) pathogenesis. Recent animal studies show that inhibiting mitochondrial complex I with rotenone closely mimics PD's biochemical and histological features. Several agents like creatine, coenzyme Q10, and acetyl-L-carnitine have shown benefits in animal models by modulating energy metabolism and reducing oxidative stress. These agents warrant further study as potential neuroprotective treatments for PD.
La conduzione del nervo surale dorsale in pazienti con carenza di vitamina B1...MerqurioEditore_redazione
This study investigated peripheral neuropathy in vitamin B12 deficient patients with megaloblastic anemia using dorsal sural nerve conduction studies and tibial sensory-evoked potentials. Dorsal sural nerve responses were absent in over half of patients but only one third had abnormalities on conventional nerve conduction studies. Patients with recordable dorsal sural nerves had prolonged latencies, reduced amplitudes, and slower conduction velocities compared to controls, suggesting dorsal sural nerve conduction is more sensitive for detecting early neuropathy. Over 70% of patients showed evidence of myelopathy on tibial sensory-evoked potentials and neurological examination.
Utilità della misurazione dei livelli di vitamina B12 e della sua frazione at...MerqurioEditore_redazione
This study evaluated vitamin B12 (VitB12) and its active fraction, holotranscobalamin (holoTC), for detecting VitB12 deficiency in 1,279 patients with neurological conditions. Elevated methylmalonic acid (MMA) levels were used as the criterion for VitB12 deficiency. Among patients with normal renal function, 13.2% had VitB12 deficiency based on MMA levels. However, VitB12 and holoTC levels showed poor correlation with VitB12 deficiency. Neither VitB12 nor holoTC demonstrated superior diagnostic accuracy for detecting VitB12 deficiency compared to the other. The study concludes that neither VitB12 nor holoTC can be reliably used
Caratteristiche cliniche e di laboratorio e risposta al trattamento in pazien...MerqurioEditore_redazione
This study examined 63 patients presenting with vitamin B12 deficiency-related neurological syndromes. The most common neurological manifestation was myeloneuropathy, seen in 54% of patients. Neuropsychiatric symptoms including dementia were observed in 38% of patients. All patients showed megaloblastic changes in bone marrow smears. Treatment with parenteral vitamin B12 injections resulted in improvement in 54% of patients after 6 months of follow up. A normal hemoglobin or MCV level does not rule out vitamin B12 deficiency.