The bottom line is that when it comes to belly fat, the answer is not in drugs or supplements. we will tell you and show you different method and what works and what don't works. https://linktr.ee/jnag1988 watch our short video guide.
12 tips to help you lose stubborn belly fatAhmed Habib
Are you intrigued by those Internet ads claiming to know "the secret to shedding belly
fat" or "the one trick to losing belly fat"? If so, you're not alone. Americans spend
countless hours and billions of dollars trying anything and everything to attain a flat
stomach.
But is there really a magic bullet — a fast and easy way to get rid of stubborn belly fat
— as so many ads and commercials claim?
By Judy Germany
Are you intrigued by those Internet ads claiming to know "the secret to shedding belly fat" or "the one trick to losing belly fat"? If so, you're not alone. Americans spend countless hours and billions of dollars trying anything and everything to attain a flat stomach.
But is there really a magic bullet — a fast and easy way to get rid of stubborn belly fat — as so many ads and commercials claim?
In short, no. (Yeah, we were bummed to hear that too.)
But, there are ways to banish belly fat — if you’re willing to make the effort.
if you need to lose weight this 30 days diet plan will help you and it will help you to understand the way of daily consumption.calories diet perfect diet
Buy Eat more weigh less Cookbook 2013 (spiral bound if purchased as hard copy) by Dr.Terry Shintani (Paperback) online at Lulu. Visit the Lulu Marketplace for product details, ratings, and reviews.
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Many people struggle with stubborn belly fat. It can be difficult to figure out how to lose your belly fat; it takes time, effort and patience. There is no easy solution unless you want to submit to expensive surgery like liposuction, which often is only a temporary fix without maintaining a proper diet and fitness routine
12 tips to help you lose stubborn belly fatAhmed Habib
Are you intrigued by those Internet ads claiming to know "the secret to shedding belly
fat" or "the one trick to losing belly fat"? If so, you're not alone. Americans spend
countless hours and billions of dollars trying anything and everything to attain a flat
stomach.
But is there really a magic bullet — a fast and easy way to get rid of stubborn belly fat
— as so many ads and commercials claim?
By Judy Germany
Are you intrigued by those Internet ads claiming to know "the secret to shedding belly fat" or "the one trick to losing belly fat"? If so, you're not alone. Americans spend countless hours and billions of dollars trying anything and everything to attain a flat stomach.
But is there really a magic bullet — a fast and easy way to get rid of stubborn belly fat — as so many ads and commercials claim?
In short, no. (Yeah, we were bummed to hear that too.)
But, there are ways to banish belly fat — if you’re willing to make the effort.
if you need to lose weight this 30 days diet plan will help you and it will help you to understand the way of daily consumption.calories diet perfect diet
Buy Eat more weigh less Cookbook 2013 (spiral bound if purchased as hard copy) by Dr.Terry Shintani (Paperback) online at Lulu. Visit the Lulu Marketplace for product details, ratings, and reviews.
weight loss,weight loss pills,weight loss calculator,weight loss surgery,weight loss programs,weight loss shakes,weight loss clinic,weight loss smoothies,weight loss foods,weight loss tea,weight loss medication,weight loss apps,weight loss affirmations,weight loss after menopause,weight loss and hair loss,weight loss after 50,weight loss aids,weight loss and diabetes,weight los
Many people struggle with stubborn belly fat. It can be difficult to figure out how to lose your belly fat; it takes time, effort and patience. There is no easy solution unless you want to submit to expensive surgery like liposuction, which often is only a temporary fix without maintaining a proper diet and fitness routine
What are the Fat Burning Foods
And Exercises that Actually Work
Fat Burning Basics
The Science of Fat Burning
Fast Fat Burning Strategies
Fat Burning Foods
Potent Foods
Fat Burning Exercises
Fat Burning Workouts Exposed
Welcome to my first issue of Bell Fat Free. If wondering how to lose tammy fat quickly, then include abdominal muscles workout in your tips to reduce belly's list.
You will discover the topics about the importance of eating the right foods and how it will help you banish stubborn belly fat from your body for good, how excess belly fat effects your overall health. hint, it changes more than your appearance, the real truth about losing lower belly fat for a sexy flat stomach, some simple, yet effective diet tips that will help you lose excess belly fat and the the connection between belly fat and diabetes and how it effects your health.
Lose 5 pounds in one week! It's a trope we see everywhere. And while it’s possible
that someone can lose that much in that time period, it really depends on your
metabolism and loads of other factors unique to you, including physical activity and
body composition.
ENRIQUE DÍAZ / 7CERO / GETTY IMAGES
SUBSCRIBE SIGN INWeight loss ultimately comes back to the concept of calories in, calories out: Eat less
than you burn and you’ll lose weight. And while it’s possible to lose water weight
quickly on a low-carb diet, I certainly wouldn’t advocate for it. The diet itself can
trick you into thinking that this eating style is working — when really, you might
gain back what you lost as soon as you eat carbs again. That can feel incredibly
dispiriting if you want results that last longer than a week.
Betterment in cardiovascular fitness is one illustration. Jogging or running supplies greater cardiovascular advantage than walking at a leisurely pace
A beginner's guide that will help you transform your body with 7 simple changes! No matter what you may think, there is no such thing as a "loophole" or "shortcut" to long term weight loss as other "fitness guru's would have you believe.
This is not a fad diet, or short term weight loss program that sometimes makes you worse off than before you started. These are proven keys that are essential to dieting success and body transformation!
Here's exactly what you'll get:
Learn the fundamentals to achieve body transformation
Discover the key to making weight loss a lifestyle
Practical advice on exercising your way to the body you've dreamed of
How to shop smart and buy foods that are nutritionally sound
And much, much more..
This powerful guide will provide you with the keys to easily transition you into living a healthy lifestyle and finally achieve your dream of dropping the fat.
Introducing Extreme Health Resolution Secrets – Resolve to Lose Weight Massively Today! Inside this eBook, you will discover the topics about getting healthy, being a winner, the facts about nutrition, health benefits besides weight loss to being fit, figuring out when you start to burn fat, and easy ways to eat healthily
It's easy to become dissatisfied with your weight loss efforts. Many people struggle to lose weight and maintain their weight loss. When you look at human metabolism in the context of a large picture of yourself, however, it's actually quite simple.
Belly fat loss the secret's to losing belly fat fast!MontanaDevis
People are called fat if they have bigger body than anyone else, much more when they have belly fat. As such, losing belly fat is one of the concerns among many today. it doesn't only impose a health risk, but a psychological torture for them seeing themselves not pleasing to look at.
Losing belly fat as always is not an easy thing to do. The more you do something worth the effort, the more you will succeed. Most people fail in their want to lose a belly fat because they stop at the middle as they cannot bear the exhaustion, and the most who succeeded are the persons who can take the challenge as in a positive way, those who find exhaustion a challenge, those who are very persevering to do it whatever it takes. So, when you want to be fit and with a flat tummy, be a positive person who can fit in into the newly adopted lifestyle for a healthier and sexier you.
To get fit, focus on eating a healthy diet and exercising regularly. First, limit the amount of processed foods in your diet, like chips, cookies, and white bread, since they can cause weight gain. Replace those foods with fruits, vegetables, whole grains, lean protein, and low-fat dairy. That way, you’ll get all the nutrients you need without empty calories. Make sure to plan healthy meals for the week in advance and get rid of unhealthy foods in your kitchen. Additionally, get in at least 150 minutes of aerobic exercise every week, like running, cycling, or swimming. Aerobic exercise is great for your heart and it burns calories. Include 2 days of strength training in your weekly routine too, since that’s how you build muscle and tone your body. Squats, push-ups, and crunches are all strength-training exercises you can do at home without any equipment. To learn more from our Personal Trainer co-author, like how to change your diet to get fit, keep reading the article!
What are the Fat Burning Foods
And Exercises that Actually Work
Fat Burning Basics
The Science of Fat Burning
Fast Fat Burning Strategies
Fat Burning Foods
Potent Foods
Fat Burning Exercises
Fat Burning Workouts Exposed
Welcome to my first issue of Bell Fat Free. If wondering how to lose tammy fat quickly, then include abdominal muscles workout in your tips to reduce belly's list.
You will discover the topics about the importance of eating the right foods and how it will help you banish stubborn belly fat from your body for good, how excess belly fat effects your overall health. hint, it changes more than your appearance, the real truth about losing lower belly fat for a sexy flat stomach, some simple, yet effective diet tips that will help you lose excess belly fat and the the connection between belly fat and diabetes and how it effects your health.
Lose 5 pounds in one week! It's a trope we see everywhere. And while it’s possible
that someone can lose that much in that time period, it really depends on your
metabolism and loads of other factors unique to you, including physical activity and
body composition.
ENRIQUE DÍAZ / 7CERO / GETTY IMAGES
SUBSCRIBE SIGN INWeight loss ultimately comes back to the concept of calories in, calories out: Eat less
than you burn and you’ll lose weight. And while it’s possible to lose water weight
quickly on a low-carb diet, I certainly wouldn’t advocate for it. The diet itself can
trick you into thinking that this eating style is working — when really, you might
gain back what you lost as soon as you eat carbs again. That can feel incredibly
dispiriting if you want results that last longer than a week.
Betterment in cardiovascular fitness is one illustration. Jogging or running supplies greater cardiovascular advantage than walking at a leisurely pace
A beginner's guide that will help you transform your body with 7 simple changes! No matter what you may think, there is no such thing as a "loophole" or "shortcut" to long term weight loss as other "fitness guru's would have you believe.
This is not a fad diet, or short term weight loss program that sometimes makes you worse off than before you started. These are proven keys that are essential to dieting success and body transformation!
Here's exactly what you'll get:
Learn the fundamentals to achieve body transformation
Discover the key to making weight loss a lifestyle
Practical advice on exercising your way to the body you've dreamed of
How to shop smart and buy foods that are nutritionally sound
And much, much more..
This powerful guide will provide you with the keys to easily transition you into living a healthy lifestyle and finally achieve your dream of dropping the fat.
Introducing Extreme Health Resolution Secrets – Resolve to Lose Weight Massively Today! Inside this eBook, you will discover the topics about getting healthy, being a winner, the facts about nutrition, health benefits besides weight loss to being fit, figuring out when you start to burn fat, and easy ways to eat healthily
It's easy to become dissatisfied with your weight loss efforts. Many people struggle to lose weight and maintain their weight loss. When you look at human metabolism in the context of a large picture of yourself, however, it's actually quite simple.
Belly fat loss the secret's to losing belly fat fast!MontanaDevis
People are called fat if they have bigger body than anyone else, much more when they have belly fat. As such, losing belly fat is one of the concerns among many today. it doesn't only impose a health risk, but a psychological torture for them seeing themselves not pleasing to look at.
Losing belly fat as always is not an easy thing to do. The more you do something worth the effort, the more you will succeed. Most people fail in their want to lose a belly fat because they stop at the middle as they cannot bear the exhaustion, and the most who succeeded are the persons who can take the challenge as in a positive way, those who find exhaustion a challenge, those who are very persevering to do it whatever it takes. So, when you want to be fit and with a flat tummy, be a positive person who can fit in into the newly adopted lifestyle for a healthier and sexier you.
To get fit, focus on eating a healthy diet and exercising regularly. First, limit the amount of processed foods in your diet, like chips, cookies, and white bread, since they can cause weight gain. Replace those foods with fruits, vegetables, whole grains, lean protein, and low-fat dairy. That way, you’ll get all the nutrients you need without empty calories. Make sure to plan healthy meals for the week in advance and get rid of unhealthy foods in your kitchen. Additionally, get in at least 150 minutes of aerobic exercise every week, like running, cycling, or swimming. Aerobic exercise is great for your heart and it burns calories. Include 2 days of strength training in your weekly routine too, since that’s how you build muscle and tone your body. Squats, push-ups, and crunches are all strength-training exercises you can do at home without any equipment. To learn more from our Personal Trainer co-author, like how to change your diet to get fit, keep reading the article!
Lose 5 pounds in one week! It's a trope we see everywhere, and if you're someone who needs to drop some weight for health reasons or simply want to for yourself, it can sound pretty enticing. Technically it's possible for some people to lose that much in that time period, but it's not something I'd recommend, and it's definitely not a healthy approach
Extreme Weight Loss Resolution Secrets ;
Would You Like to Know Exactly What to Eat to Lose Fat and Get Healthy Without Giving Up Your Favorite Foods or Starving Yourself?
Click here to discover the top secret to loose weight fast and effective : https://bit.ly/3BqzhCO
Top 10 tips to lose weight fast and never get it backNuman Rao
If you have tried everything to lose weight and nothing works for you, we tell you two dozen tricks that you have to carry out to succeed and achieve your weight goa
You will discover the topics about the importance of eating the right foods and how it will help you banish stubborn belly fat from your body for good, how excess belly fat effects your overall health. Hint, it changes more than your appearance, the real truth about losing lower belly fat for a sexy flat stomach, some simple, yet effective diet tips that will help you lose excess belly fat and the connection between belly fat and diabetes and how it affects your health.
7 BEST EXERCISES TO LOSE BELLY FAT AT HOMELovettEssouma
Isn't it amazing - and so frustrating! - how easy it is to gain weight? Our bodies are like magnets that seem to attract and pile up excess pounds as soon as our guard is down. All it takes is a couple of rich desserts, a few weeks on vacation or the Christmas holidays…bam! Our waistline has expanded in proportion to our indulgences.
Conversely, losing weight can be a grueling struggle. For some people, staying fit and maintaining a healthy weight is an unending cycle of diets, weight loss schemes and exercise programs.
However, everybody who has struggled to lose weight will unanimously agree on one thing: the most frustrating issue has got to be belly fat. Nothing is more unattractive. Nothing is more frustrating than that "spare tire" around your waistline.
Belly fat is that ugly layer of flab around our bellies and when we are trying to lose weight, it's usually the last to go.
How to lose weight in simple steps it's a quick guide to weight loss for beginners.
In this short document, you can find ideeas and articles like simple solutions for quick weight loss, 9 super foods to help weight loss, about if there are any weight loss wonders, about the beginning your weight loss journey and being in the mood for weight loss, how to burn calories for weight loss and common myths about weight loss.
If you have tried before quick weight loss and experienced an even quicker weight gain back, there are some things that could be done and starts from a healthy life, with nutrient foods, with some exercises – regarding diets, that should not exist anymore, the change must be profound for an active life style, with energy from healthy food.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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1. Are you intrigued by those Internet ads claiming to know "the secret to
shedding belly fat" or "the one trick to losing belly fat"? If so, you're not
alone. Americans spend countless hours and billions of dollars trying
anything and everything to attain a flat stomach.
But is there really a magic bullet — a fast and easy way to get rid of
stubborn belly fat — as so many ads and commercials claim?
In short, no. (Yeah, we were bummed to hear that too.)
But, there are ways to banish belly fat — if you’re willing to make the
effort.
Two experts from Rush, Rasa Kazlauskaite, MD, an endocrinologist
with the Rush University Prevention Center, and Sheila Dugan, MD, a
physical medicine and rehabilitation specialist, help guide you through
the changes you need to make to lose that belly fat for good.
First of all, what is belly fat?
To better understand what were talking about
Watch this short video by clicking the link below
1. https://linktr.ee/jnag1988
There are different types of fat:
Subcutaneous fat
Subcutaneous fat is the looser fat that lets you "pinch an inch" and
can accumulate just under the skin
Intramuscular fat
Intramuscular fat is found within the skeletal muscles
2. Visceral fat
Visceral fat is the packed between your abdominal organs (stomach,
liver, kidneys, etc.), which is what we call intra-abdominal or belly fat
Is there really ‘one trick’ to losing belly fat?
When ads claim a "one trick" solution, remember that their main
objective is to sell their product rather than to help you. Good
marketing means one message, because it is hard to follow too many
things at once. So they focus on one fad, and that tickles your
curiosity and you click on the link to go their website.
So, no, there's not. But here's what you can do.
1. Start simple
Typically there are many things you may need to improve to lose belly
fat. But start by focusing on changing or improving just one thing.
Then, once you conquer that first objective, you can move on to the
next thing, and so on.
2. Target sugar
One good place to begin improving your food choices is to eliminate
sugary drinks — and not just soda, but juices. Sugar increases belly
fat and fiber reduces belly fat; thus when you're juicing fruits, you're
removing the fiber, leaving pure sugar. So one quick fix, a very
concrete fix, would be eliminating sugary drinks.
Replacing sugary beverages with water will help dramatically cut down
your sugar intake, and then once you've taken that step, you can
figure out how to cut down on foods that are high in sugar.
3. If you have a sweet tooth and need to put that final accent to your
meal, eat an apple, melon or fresh berries. Just remember, fruit is not
a substitute for vegetables.
3. Go Mediterranean
The popular "flat belly diets"embrace much of the wisdom found in
eating a Mediterranean diet, which helps everything from brain health
to hearth health. The basic premise for both diets is eat foods rich in
monosaturated fatty acids (MUFA) that may help reduce your belly fat
storage. MUFA-rich foods include olive oil, nuts and seeds, avocodos,
and fish. Eating yogurt regularly has also been found to be helpful in
reducing belly fat.
Another diet trend that promises results when it comes to belly fat: the
apple cider vinegar diet. While animal studies have been promising,
current research in humans has yet to show impressive results. The
data supporting the benefits of the Mediterranean diet, however, are
real and cause for making some dietary changes.
4. Front-load your meal
Start your meal, especially your largest meal, with seasoned
vegetables, be it vegetable soup or the vegetables on your entrée
plate. And remember that vegetables should always comprise at least
half of your plate and be a mix of starchy (like potatoes) and
nonstarchy ones (your leafy greens, broccoli, etc.).
Eating the vegetables first will leave less room for other foods that
aren't as healthy, because vegetable fiber is filling.
5. Commit to a physical lifestyle
4. The single most important thing people can do to prevent the buildup
of belly fat and get rid of existing belly fat is commit to physical activity,
and better yet, a physical lifestyle.
For both men and women, the first fat you lose when you exercise is
visceral fat.
In a way, moderate-intensity physical activity is that "magic pill" a lot of
people are looking for, because the health benefits go beyond keeping
your waistline trim: Not only can it reduce your risk of cancer, stroke,
diabetes and heart attacks, but studies have shown that physical
activity can significantly improve the moods of patients with major
depressive disorders.
Overtraining, though, can be problematic when it comes to fighting
belly fat because it can lead to coristol overproduction. Excess
amounts of this stress hormone has been found to be associated with
belly fat.
Simply walking briskly an hour each day can have an impact by
boosting your metabolism, as can adding an incline to your treadmill
routine.
The bottom line is that when it comes to belly fat, the
answer is not in drugs or supplements.
6. Move around, fidget
Here's something else most people probably don't know: Fidgeting is
good for you. It's considered a nonexercise physical activity, and it's
an important way to burn energy. You get more health benefits if, in
addition to exercising, you are a more fidgety, more active person the
5. rest of the day. This means gesturing while you're talking, tapping
your foot, just moving around.
7. And try not to sit too much
Studies have shown that people who sit eight to nine hours a day,
even if they exercise the recommended 150 minutes per week, do not
get the same benefits of exercising as people who are more active
throughout the day.
If you have to sit most of the day for your job, try to find some ways to
move:
● Take small breaks throughout the day to walk around
● Use your lunch hour to take a longer walk
● Take the stairs instead of the elevator, if possible
● Do stretching exercises at your desk
● Just do your best to move around as much as you can
8. Redefine 'rest'
Having an active hobby — and if you don't already have one,
developing one — is important. Get engaged in some kind of sport,
whether it's a group activity or something you can do alone.
Essentially, if an activity is pleasant to you, you'll continue to do it.
If your leisure time involves sitting around on the sofa or in a chair,
you might actually be offsetting the positive health effects of exercising
even if you're working out regularly.
Unfortunately, the general understanding of rest is relaxing in front of
TV or dining out — what we call "passive rest." But really, our rest
should consist of sleep, and our leisure time should consist of fun
physical activity, which is active rest.
6. To better understand what were talking about
Watch this short video by clicking the link below.
1.https://linktr.ee/jnag1988
Statistics suggest that out of 900 months in his life, the average man
in the U.S. spends approximately 198 months watching TV, five
months complaining about his boss, and five months waiting on hold.
Think of the other things you could do with those 208 months of your
life. You could find activities that are better for your health and will
help keep the belly fat away.
9. Don't rely on sit-ups to give you a six-pack
Unfortunately, sit-ups and crunches can't eliminate visceral fat directly.
You can't reduce fat from specific parts of your body by exercising that
body part; our bodies simply don't work that way.
With sit-ups or other abdominal exercises, you're toning the abdominal
muscles but not burning intra-abdominal fat. The key is to lower your
overall body fat with moderate-intensity physical activity and a healthy
diet; when you reduce your total body fat, you'll also be reducing your
belly fat.
So if you want to do abdominal exercises, make them part of your
fitness routine. Just don't treat them as a substitute for the
recommended 150 minutes of weekly moderate-intensity physical
activity.
10. Develop more muscle
While sit-ups can't "target" belly fat, what they can do is help you burn
calories, strengthen your core and develop more muscle. Because
7. muscle is more metabolically active than fat, the more muscle you
have, the more calories you'll burn when you're at rest.
You can also try lifting heavier weights and resting less between
repetitions, which can promote calorie burning after you leave the
gym.
Burning those extra calories can help you achieve and maintain a
healthier weight in conjunction with regular cardiovascular exercise
and a healthy diet.
11. Get some sleep
A recent study of 70,000 individuals showed that those getting less
than five hours of sleep were more likely to gain 30 or more pounds.
12. Forget about weight loss drugs or supplements
claiming ‘one trick’
So far, there is not one single drug that is approved by the Federal
Drug Administration for the reduction of belly fat. Supplements
claiming a "one trick solution" to belly fat are not strictly regulated, and
a lot of the claims made in the ads are not backed up by research.
The bottom line is that when it comes to belly fat, the answer is not in
drugs or supplements. Enjoying a healthy lifestyle should be the focus.
And while that's not as simple as swallowing a pill, the benefits will last
a lifetime.