The commentary on Jeremiah 27 discusses the confusion surrounding the dating of Jeremiah's prophecies, originally attributed to the reign of Jehoiakim but more accurately linked to Zedekiah. It highlights the significance of Jeremiah's symbolic act of wearing an ox yoke to convey God's message of submission to Babylonian rule, emphasizing the futility of resistance against Nebuchadnezzar. Additionally, the commentary underscores the role of false prophets and the importance of heeding God's warning against forming alliances that could lead to destruction.