ICD-10 is the 10th revision of the International Statistical Classification of Diseases and Related Health Problems, containing over 14,400 medical codes. The transition from ICD-9 to ICD-10 in the US, which was mandated for October 2015, will significantly impact healthcare revenue cycle management due to the increased specificity of codes, resulting in changes to documentation practices, reimbursement amounts, and potential increases in claim denials during the transition period. Healthcare organizations need to proactively address contract negotiations and dispute resolution procedures to mitigate financial risks from the ICD-10 transition.