Use of laboratory instruments and specimen processing equipment to perform clinical laboratory assays with only minimal involvement of technologist .
Automation in clinical laboratory is a process by which analytical instruments perform many tests with the least involvement of an analyst.
The International Union of Pure and Applied Chemistry (IUPAC) define automation as "The replacement of human manipulative effort and facilities in the performance of a given process by mechanical and instrumental devices that are regulated by feedback of information so that an apparatus is self-monitoring or self adjusting”.
Micro-Electro-Mechanical Systems, or MEMS, is a technology that in its most general form can be defined as miniaturized mechanical and electro-mechanical elements (i.e., devices and structures) that are made using the techniques of microfabrication. The critical physical dimensions of MEMS devices can vary from well below one micron on the lower end of the dimensional spectrum, all the way to several millimeters. Likewise, the types of MEMS devices can vary from relatively simple structures having no moving elements, to extremely complex electromechanical systems with multiple moving elements under the control of integrated microelectronics. The one main criterion of MEMS is that there are at least some elements having some sort of mechanical functionality whether or not these elements can move. The term used to define MEMS varies in different parts of the world. In the United States they are predominantly called MEMS, while in some other parts of the world they are called “Microsystems Technology” or “micromachined devices”.
Introduction to Mechatronics, Sensors and Transducerstaruian
Introduction: Definition, Multidisciplinary Scenario, Evolution of Mechatronics, Design of Mechatronics system, Objectives, advantages and disadvantages of Mechatronics
Transducers and sensors: Definition and classification of transducers, Difference between transducer and sensor, Definition and classification of sensors, Principle of working and applications of light sensors, proximity switches and Hall Effect sensors.
Spectrolytic was founded with the aim of making spectroscopy solutions available to the masses and to broaden the view of usability.
Spectrolytic GmbH is a developer and supplier of infrared spectrometers and related solutions for a wide range of applications and markets. It also provides development and manufacturing services to third parties for both systems and solutions.
Spectrolytic GmbH has its registered office in Wernberg-Köblitz, Germany, and its operating HQ in Wackersdorf, Germany. The Companies design, manufacture (internally and/or externally) a range of spectroscopy systems for a number of market sectors including but not limited to industrial and consumer applications.
The Company also provide technology consulting, system design and development services, plus related manufacturing to customers on a contract basis.
We believe we have some of the greatest minds in our business and will utilize this capability to expand our business to the benefits of the team and all stakeholders.
Phage Display Screening for Single Domain Antibody (sdAb)ShawVivian
Phage display screening(https://www.creative-biolabs.com/sdab/phage-display-screening-for-single-domain-antibody-sdab.htm) is a well-established technique to identify antibody fragments and other binding molecules against any targets of interest. As each clone in phage display libraries represents a noncombinatorial functional domain of a naturally circulating antibody, phage display screening is a powerful method for sdAb discovery. Here, Creative Biolabs describes the phage display screening for sdAb generation.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
Use of laboratory instruments and specimen processing equipment to perform clinical laboratory assays with only minimal involvement of technologist .
Automation in clinical laboratory is a process by which analytical instruments perform many tests with the least involvement of an analyst.
The International Union of Pure and Applied Chemistry (IUPAC) define automation as "The replacement of human manipulative effort and facilities in the performance of a given process by mechanical and instrumental devices that are regulated by feedback of information so that an apparatus is self-monitoring or self adjusting”.
Micro-Electro-Mechanical Systems, or MEMS, is a technology that in its most general form can be defined as miniaturized mechanical and electro-mechanical elements (i.e., devices and structures) that are made using the techniques of microfabrication. The critical physical dimensions of MEMS devices can vary from well below one micron on the lower end of the dimensional spectrum, all the way to several millimeters. Likewise, the types of MEMS devices can vary from relatively simple structures having no moving elements, to extremely complex electromechanical systems with multiple moving elements under the control of integrated microelectronics. The one main criterion of MEMS is that there are at least some elements having some sort of mechanical functionality whether or not these elements can move. The term used to define MEMS varies in different parts of the world. In the United States they are predominantly called MEMS, while in some other parts of the world they are called “Microsystems Technology” or “micromachined devices”.
Introduction to Mechatronics, Sensors and Transducerstaruian
Introduction: Definition, Multidisciplinary Scenario, Evolution of Mechatronics, Design of Mechatronics system, Objectives, advantages and disadvantages of Mechatronics
Transducers and sensors: Definition and classification of transducers, Difference between transducer and sensor, Definition and classification of sensors, Principle of working and applications of light sensors, proximity switches and Hall Effect sensors.
Spectrolytic was founded with the aim of making spectroscopy solutions available to the masses and to broaden the view of usability.
Spectrolytic GmbH is a developer and supplier of infrared spectrometers and related solutions for a wide range of applications and markets. It also provides development and manufacturing services to third parties for both systems and solutions.
Spectrolytic GmbH has its registered office in Wernberg-Köblitz, Germany, and its operating HQ in Wackersdorf, Germany. The Companies design, manufacture (internally and/or externally) a range of spectroscopy systems for a number of market sectors including but not limited to industrial and consumer applications.
The Company also provide technology consulting, system design and development services, plus related manufacturing to customers on a contract basis.
We believe we have some of the greatest minds in our business and will utilize this capability to expand our business to the benefits of the team and all stakeholders.
Phage Display Screening for Single Domain Antibody (sdAb)ShawVivian
Phage display screening(https://www.creative-biolabs.com/sdab/phage-display-screening-for-single-domain-antibody-sdab.htm) is a well-established technique to identify antibody fragments and other binding molecules against any targets of interest. As each clone in phage display libraries represents a noncombinatorial functional domain of a naturally circulating antibody, phage display screening is a powerful method for sdAb discovery. Here, Creative Biolabs describes the phage display screening for sdAb generation.
Creative Biolabs offers a comprehensive range of quality recombinant antibodies for cell & organelle imaging. These antibodies are covering significant research areas such as cancer research, cell signaling, cell morphology and organelle detection.
Live cell imaging is the study of living cells using time-lapse microscopy. Scientists use it to better understand and validate the biological function through the study of cellular dynamics. Organelles are specialized and well-defined parts of the cell which are usually separately enclosed within their own lipid bilayers. Very often organelles have to be stained to follow cellular processes and the effects of changing parameters on these processes. Thus, there is a great significance and strong need for tools to stain and follow specific organelles in living cells.
https://www.antibody-creativebiolabs.com/category-introduction/cell-organelle-imaging-3.htm
Thanks to a longstanding presence in the market of sdAb development and our well-established screening platform, Creative Biolabs is the right partner to navigate the sdAb screening challenges. Focused on the field of sdAb discovery and development, we will use our skills to offer innovative and sophisticated sdAb screening services tailored to our customer's exact needs.
Secondary antibodies bind to the primary antibody to assist in detection, classification and isolation of interest antigen. To ensure detection, the secondary antibody must be specific for the isotype and antibody species of the primary antibody in the application. Secondary antibodies are typically polyclonal.
Secondary antibody conjugates are important tools in biochemical and cell-based analysis. Enzyme-labeled secondary antibodies have high catalytic turnover rates and are routinely used in various assays for their robust and rapid signal generation. Secondary antibodies conjugated to fluorescent dyes offer brighter signals and multiplexing capabilities in cell analysis and protein analysis applications including immunofluorescence microscopy and cell imaging. For both enzyme-labeled and dye-labeled secondary antibodies, high sensitivity and signal amplification are two desirable qualities when detecting target antigens of low abundance.
Antibody pair is two different antibodies developed against the same target that with different binding regions or epitopes. Differential epitope recognition renders simultaneous binding of both antibodies to the same target, to form sandwich ELISA format. Antibody pair can be used to detect and quantify interaction molecules in situ, ensure localization of sub-cellular events, reduce the risk of missing weak or transient interactions and improve detection specificity and sensitivity. Creative Biolabs has years of expertise in developing antibody pairs to provide a monoclonal antibody pair, a polyclonal antibody pair, or a combination for your specific requirement. Our high-quality products are suitable for used to quantify target analyte from complex samples across various fields including cancer, autoimmune, metabolic disease, endocrine, infectious disease, etc.
https://www.antibody-creativebiolabs.com/category/antibody-pairs-129.htm
Antibody arrays have emerged as an important tool, which enable multiplexed protein expression profiling such as cytokines, chemokines and growth factors, which may be involved in diseases. To design high-performing antibody arrays, it is necessary to develop an integrated technology platform, where the interplay between the surfaces and the antibody is anticipated to play an important role.
https://www.antibody-creativebiolabs.com/category/glass-slide-antibody-arrays-126.htm
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample volumes. The earliest and most widely used application of antibody arrays has been to measure multiple protein abundances, using sandwich assays and label-based assays, for biomarker discovery and biological studies. Modifications to these assays have led to studies profiling specific protein post-translational modifications, such as protein phosphorylation that is a mechanism of regulation that is extremely important in most cellular processes.
https://www.antibody-creativebiolabs.com/category-introduction/antibody-array-analysis-132.htm
Creative Biolabs provides a comprehensive range of recombinant antibodies of the key tumor for research processes and diagnostic assay developments for our clients. here is PIK3CA antibody for breast cancer.
https://www.antibody-creativebiolabs.com/category-introduction/tumor-marker-detection-1.htm
Single domain antibodies (sdAbs, or VHH) are the smallest antigen-binding units of antibodies, comprising either one variable domain or one engineered constant domain that solely facilitates target binding. They are popular as a novel class of proprietary therapeutic proteins containing unique structural and functional properties. At Creative Biolabs, we offer one-stop solutions for sdAb development and characterization to promote the identification of novel therapeutic sdAbs to meet your specific project demands.
https://www.creative-biolabs.com/sdab/sdab-functional-identification.htm
Next-generation sequencing (NGS) plays an important role in cancer diagnostics. Creative Biolabs offers SuPrecision™ Platform covering a full range of NGS-based services. This tool greatly improves our understanding of the multifaceted disease and achieves accurate, sensitive, high-throughput and cost effective cancer detection.
The genome diversity within an ecosystem of single cell species is far greater than currently accurate measurement. In the era of precision medicine, single cell genomics omics technology is highly promising owing to its potential in diagnosis, therapeutics, and prognosis. As a skillful expert in the single cell analysis, Creative Biolabs is committed to advancing clients' significant programs and provides end-to-end solutions for any challenging single cell genomics projects through our advanced platforms and bioinformatics profiling.
https://singlecell.creative-biolabs.com/single-cell-genomics-platform.htm
An ongoing outbreak of a novel coronavirus (SARS-CoV-2) has raised global concerns. It is identified as the cause of pneumonia with unknown etiology. Since the early outbreak in Wuhan, China, it has subsequently spread to all provinces of China and many other countries. The urgent epidemic situation has spurred the development of antiviral drugs and vaccines. As a leading service provider in the field of biological research and drug discovery, Creative Biolabs provides fast & elaborate therapeutic antibody discovery, drug candidates screening and vaccine development services to help combat this outbreak.
https://sars-cov-2.creative-biolabs.com/novel-coronavirus-sars-cov2.htm
Creative Biolabs is skilled in NGS-based cancer research. We support one-stop cancer research services based on a variety of sequencing technologies. Our whole gene sequencing (WGS) and whole exome sequencing (WES) platforms enable us to comprehensively analyze and identify known and unknown cancer gene mutations. Besides, we also provide high-quality target sequencing services, allowing us to analyze several or even hundreds of target gene mutations economically and effectively. Our services will facilitate our customers’ cancer research including cancer diagnosis and treatment.
https://www.creative-biolabs.com/suprecision/genetic-testing-for-cancer.htm
Creative Biolabs’ technical experts have successfully established the proprietary complement therapeutics system. We are looking forward to designing a strategy to carry on the therapeutic antibodies development services for our clients in complement therapeutic.
a full range of complement therapeutic services and complement based drug discovery services for customers at https://www.creative-biolabs.com/complement-therapeutics/
diversified species genetic information and a wide
range of antibodies information and one-stop customized service at https://modelorg-ab.creative-biolabs.com/
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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