The Highway of Tears in British Columbia refers to a 724km stretch of Highway 16 between Prince Rupert and Prince George where over 30 women and girls have been murdered or gone missing over the past 35 years. The document warns travelers to exercise caution and consider travelling with others when using this highway due to the ongoing issue of violence against women in the area. It provides contact information for organizations that can offer assistance or accept tips regarding any past or current crimes.