GPCRs are generally made of many transmembrane helices which form a bi.pdf
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GPCRs are generally made of many transmembrane helices which form a binding pocket within the bundled helices. Because of this, the signal binding site is often: Within the plane of the membrane On the cytosolic side with the G protein Initially on the extracellular side, then transported through into the cytosol Extended into the extracellular space.
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