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Supervisor
Dr.Razi
Provisioner
Nazila gharibi
winter 1399
➢ by Site- Specific Recombinases )SSRs(
➢ by Site- Specific Nucleases )SSNs(
✓ Cre/loxP
✓ Flp/FRT
Site- specific recombination
MegaNuclease
ZFN
Zinc finger nucleases
TALEN
Transcription activator-like
effector nucleases
CRISPER
Clustered regularly interspaced short
palindromic repeats
(Protospacers)
(Protospacers)
(repeated sequence)
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