Genetic Technologies is a diversified molecular diagnostics company. A global leader in genomics-based tests in health, wellness and serious disease through its geneType and EasyDNA brands. GENE offers cancer predictive testing and assessment tools to help physicians to improve health outcomes for people around the world. The Company has a proprietary risk stratification platform that has been developed over the past decade and integrates clinical and genetic risk to deliver actionable outcomes to physicians and individuals. Leading the world in risk prediction in oncology, cardiovascular and metabolic diseases, Genetic Technologies continues to develop risk assessment products.
Genetic Technologies (NASDAQ: GENE) is a diversified molecular diagnostics company embracing blockchain technologies across genomic testing platforms. GENE offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead product, BREVAGenplus®, is a clinically validated risk assessment test for non-hereditary breast cancer and is first in its class. For more information, please visit genetechinfo.com.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies is a diversified molecular diagnostics company. A global leader in genomics-based tests in health, wellness and serious disease through its geneType and EasyDNA brands. GENE offers cancer predictive testing and assessment tools to help physicians to improve health outcomes for people around the world. The Company has a proprietary risk stratification platform that has been developed over the past decade and integrates clinical and genetic risk to deliver actionable outcomes to physicians and individuals. Leading the world in risk prediction in oncology, cardiovascular and metabolic diseases, Genetic Technologies continues to develop risk assessment products.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies (NASDAQ: GENE) is a diversified molecular diagnostics company embracing blockchain technologies across genomic testing platforms. GENE offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead product, BREVAGenplus®, is a clinically validated risk assessment test for non-hereditary breast cancer and is first in its class. For more information, please visit genetechinfo.com.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies is a diversified molecular diagnostics company. A global leader in genomics-based tests in health, wellness and serious disease through its geneType and EasyDNA brands. GENE offers cancer predictive testing and assessment tools to help physicians to improve health outcomes for people around the world. The Company has a proprietary risk stratification platform that has been developed over the past decade and integrates clinical and genetic risk to deliver actionable outcomes to physicians and individuals. Leading the world in risk prediction in oncology, cardiovascular and metabolic diseases, Genetic Technologies continues to develop risk assessment products.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies Limited is a diversified molecular diagnostics company developing tools for the prediction and assessment of chronic disease risk to help physicians proactively manage patient health. The Company’s lead products, ‘GeneType for Breast Cancer’ and ‘GeneType for Colorectal Cancer’, are clinically validated risk assessment tests that are first in their class. The Company signed a multi-year distribution agreement for its COVID-19 Risk Test and remains on track to launch its revolutionary Multi-Test, covering up to 70% of mortalities and morbidities, including major oncological, metabolic, and degenerative diseases. Genetic Technologies recent acquisition of EasyDNA has significantly accelerated the Company’s commercialization strategy, providing established revenue streams and direct-to-consumer marketing channels that include 70 websites in 40 countries. Listed on the ASX in 2000 and NASDAQ in 2005, Genetic Technologies has been a leader in the development and commercialization of genetic risk assessment technology for 20 years.
Genetic Technologies Limited is a diversified molecular diagnostics
company developing tools for the prediction and assessment of cancer
risk to help physicians proactively manage patient health. The
Company’s lead products, ‘GeneType for Breast Cancer’ and
‘GeneType for Colorectal Cancer’, are clinically validated risk
assessment tests that are first in their class. The Company’s
development pipeline includes new tests for COVID-19, Type 2
diabetes, cardiovascular disease, prostate cancer, and melanoma.
Listed on the ASX in 2000 and NASDAQ in 2005, Genetic
Technologies has been a leader in the development and
commercialization of genetic risk assessment technology for 20 years.
Exact Sciences Company Presentation Baird Healthcare ConferenceExact Sciences
Exact Sciences CEO Kevin Conroy's presentation slides, featuring updates on Cologuard's commercial launch, from the 2014 Baird Healthcare Conference September 4, 2014.
Exact Sciences chairman and CEO Kevin Conroy delivered the company's presentation at the 2015 Baird 2015 Healthcare Conference in New York at 9:40 a.m. ET on Wednesday, Sept. 9.
An archive of the webcast is available here: http://wsw.com/webcast/baird43/register.aspx?conf=baird43&page=exas&url=http://wsw.com/webcast/baird43/exas/index.aspx
Download Global breast cancer vaccine market & clinical pipeline outlook ...KuicK Research
“Global Breast Cancer Vaccine Market and Clinical Pipeline Outlook 2022” report analyzes ongoing clinical and non-clinical trends in the global breast cancer vaccine development market. Currently there is no single breast cancer vaccine commercially available in the market. This report analyzes the ongoing clinical trial of 36 breast cancer vaccines in clinical pipeline and gives comprehensive clinical insight on various parameters associated with the development of the vaccine. Most of the breast cancer vaccines in clinical trials are in preclinical phase followed by Phase-I trials. The advance stage of development of breast cancer vaccine in clinical trials across the globe is in Phase-III.
The conventional cancer treatment methods have proved their importance in last decade. They are widely accepted among patients and physicians (oncologists) because of familiarity and large amount of statistically significant data supporting their efficacy. Despite their benefits, they sometimes fall short in meeting the patient’s personal requirements. For instance, efficacy is a major requirement, but different patients display different response to the same medication, this is attributed to their unique genetic makeup. To meet the individual’s necessities, high efficacy and safety, concept of cancer vaccine was formulated.
"US Cancer Vaccine Market Outlook 2020" Report Highlight:
US Cancer Vaccine Market Analysis
Cancer Vaccine with Orphan Status
US Cancer Vaccine Clinical Pipeline by Company, Indication & Phase
US Cancer Vaccine Clinical Pipeline: 187 Vaccines
Clinical Insight of Marketed Cancer Vaccines in US
Marketed Cancer Vaccine in US: 5 Vaccines
FDA Regulations for Clinical Trials of Cancer Vaccines
Based in Ann Arbor, Michigan, Zomedica is a veterinary health company creating diagnostic and therapeutic products for horses, dogs, and cats by focusing on the unmet needs of clinical veterinarians. With modest cash burn and a strong balance sheet, including $142.4 million cash and cash equivalents as of June 30, 2023, Zomedica is well-positioned to fund both organic growth and acquisitions.
Dócola is a social good organization with the only free care communication platform that consolidates thousands of free and low-cost patient education resources from the leading nonprofit, government, and commercial organizations in one marketplace. Plus, you can easily create and upload your own resources.
Genetic Technologies Limited (ASX: GTG; Nasdaq: GENE), a diversified molecular diagnostics company. GTG offers cancer predictive testing and assessment tools to help physicians proactively manage patient health. The Company’s lead products GeneType for Breast Cancer and GeneType for Colorectal Cancer are clinically validated risk assessment tests and are first in class. Genetic Technologies is developing a pipeline of risk assessment products. Learn more at GENETechinfo.com.
Genetic Technologies Limited is a diversified molecular diagnostics company developing tools for the prediction and assessment of chronic disease risk to help physicians proactively manage patient health. The Company’s lead products, ‘GeneType for Breast Cancer’ and ‘GeneType for Colorectal Cancer’, are clinically validated risk assessment tests that are first in their class. The Company signed a multi-year distribution agreement for its COVID-19 Risk Test and remains on track to launch its revolutionary Multi-Test, covering up to 70% of mortalities and morbidities, including major oncological, metabolic, and degenerative diseases. Genetic Technologies recent acquisition of EasyDNA has significantly accelerated the Company’s commercialization strategy, providing established revenue streams and direct-to-consumer marketing channels that include 70 websites in 40 countries. Listed on the ASX in 2000 and NASDAQ in 2005, Genetic Technologies has been a leader in the development and commercialization of genetic risk assessment technology for 20 years.
Genetic Technologies Limited is a diversified molecular diagnostics
company developing tools for the prediction and assessment of cancer
risk to help physicians proactively manage patient health. The
Company’s lead products, ‘GeneType for Breast Cancer’ and
‘GeneType for Colorectal Cancer’, are clinically validated risk
assessment tests that are first in their class. The Company’s
development pipeline includes new tests for COVID-19, Type 2
diabetes, cardiovascular disease, prostate cancer, and melanoma.
Listed on the ASX in 2000 and NASDAQ in 2005, Genetic
Technologies has been a leader in the development and
commercialization of genetic risk assessment technology for 20 years.
Exact Sciences Company Presentation Baird Healthcare ConferenceExact Sciences
Exact Sciences CEO Kevin Conroy's presentation slides, featuring updates on Cologuard's commercial launch, from the 2014 Baird Healthcare Conference September 4, 2014.
Exact Sciences chairman and CEO Kevin Conroy delivered the company's presentation at the 2015 Baird 2015 Healthcare Conference in New York at 9:40 a.m. ET on Wednesday, Sept. 9.
An archive of the webcast is available here: http://wsw.com/webcast/baird43/register.aspx?conf=baird43&page=exas&url=http://wsw.com/webcast/baird43/exas/index.aspx
Download Global breast cancer vaccine market & clinical pipeline outlook ...KuicK Research
“Global Breast Cancer Vaccine Market and Clinical Pipeline Outlook 2022” report analyzes ongoing clinical and non-clinical trends in the global breast cancer vaccine development market. Currently there is no single breast cancer vaccine commercially available in the market. This report analyzes the ongoing clinical trial of 36 breast cancer vaccines in clinical pipeline and gives comprehensive clinical insight on various parameters associated with the development of the vaccine. Most of the breast cancer vaccines in clinical trials are in preclinical phase followed by Phase-I trials. The advance stage of development of breast cancer vaccine in clinical trials across the globe is in Phase-III.
The conventional cancer treatment methods have proved their importance in last decade. They are widely accepted among patients and physicians (oncologists) because of familiarity and large amount of statistically significant data supporting their efficacy. Despite their benefits, they sometimes fall short in meeting the patient’s personal requirements. For instance, efficacy is a major requirement, but different patients display different response to the same medication, this is attributed to their unique genetic makeup. To meet the individual’s necessities, high efficacy and safety, concept of cancer vaccine was formulated.
"US Cancer Vaccine Market Outlook 2020" Report Highlight:
US Cancer Vaccine Market Analysis
Cancer Vaccine with Orphan Status
US Cancer Vaccine Clinical Pipeline by Company, Indication & Phase
US Cancer Vaccine Clinical Pipeline: 187 Vaccines
Clinical Insight of Marketed Cancer Vaccines in US
Marketed Cancer Vaccine in US: 5 Vaccines
FDA Regulations for Clinical Trials of Cancer Vaccines
Based in Ann Arbor, Michigan, Zomedica is a veterinary health company creating diagnostic and therapeutic products for horses, dogs, and cats by focusing on the unmet needs of clinical veterinarians. With modest cash burn and a strong balance sheet, including $142.4 million cash and cash equivalents as of June 30, 2023, Zomedica is well-positioned to fund both organic growth and acquisitions.
Dócola is a social good organization with the only free care communication platform that consolidates thousands of free and low-cost patient education resources from the leading nonprofit, government, and commercial organizations in one marketplace. Plus, you can easily create and upload your own resources.
INNO HOLDINGS INC. is an innovative building-technology company with a mission to transform the construction industry with our proprietary cold-formed steel- framing technology and other building innovations
Everything Blockchain builds platforms of trust for the modern enterprise and is on a mission to ensure every organization has access to the tools and platforms that enable them to manage, store, and protect data without the cost and complexity that holds them back today. The Company’s patented advances in engineering deliver the essential elements needed for real-world business use: speed, security, and efficiency. Everything Blockchain’s current business lines include: EB Advise, Build DB and EB Control.
ASP Isotope is an isotope enrichment company utilizing technology developed in South Africa over the past 20 years to enrich isotopes of elements or molecules with low atomic masses. Many of these elements are unsuitable for enrichment using traditional methods such as centrifuges. The Company’s initial focus is on producing and commercializing highly enriched isotopes for the healthcare and technology industries.
MDNA Life Sciences is a pioneer in the science of mitochondrial DNA. It’s our mission to create an extensive portfolio of proprietary tests that dramatically improve diagnosis, treatment, prognosis and monitoring. Putting an end to the unnecessary surgical procedures, pain and uncertainty that affect patients across the world.
Digital Ally, Inc. is a diversified holding company with operations in video solution technology, human and animal health protection products, healthcare revenue cycle management, ticket brokering and marketing, and event production. The Company pursues an acquisition strategy that targets organizations with positive earnings, strong growth potential, innovation, and operational synergies. To maximize long-term shareholder value, Digital Ally intends to spin-off its ticketing and entertainment business lines into a separate public company in 2023. The spin-off will create two optimized, tech-driven public companies with strong growth opportunities and operating metrics.
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
Sharps Technology is a medical device and pharmaceutical packaging company specializing in the development and manufacturing of innovative drug delivery systems. The Company’s product lines focus on low waste and ultra-low waste syringe technologies that incorporate both passive and active safety features. These features protect front line healthcare workers from life-threatening needle stick injuries and protect the public from needle re-use. Sharps Technology has extensive expertise in specialized prefilled syringe systems and is on track to launch this new product line in Q4 2023. The Company has a manufacturing facility in Hungary and has partnered with Nephron Pharmaceuticals to expand its manufacturing capacity in the US.
Aditxt is a global innovation company focused on discovering and developing precision medicine innovations and deploying them into high-performing businesses. Aditxt’s diverse innovation portfolio includes: Adimune™, Inc., developing and designing a new class of therapeutics for retraining the immune system to address organ rejection, autoimmunity, and allergies; Adivir™, Inc., focused on identifying, developing and commercializing new ways to treat infectious diseases; and Pearsanta™, Inc., offering convenient, rapid, personalized, and high-quality lab testing —anytime and anywhere at its CLIA certified and CAP accredited clinical laboratory based in Richmond, VA.
1847 Holdings LLC, a publicly traded diversified acquisition holding company, was founded by Ellery W. Roberts, a former partner of Parallel Investment Partners, Saunders Karp & Megrue and Principal of Lazard Freres Strategic Realty Investors. EFSH's investment thesis is that capital market inefficiencies have left the founders and/or stakeholders of many small business enterprises and lower-middle market businesses with limited exit options, despite the intrinsic value of their business. Given this dynamic, EFSH can consistently acquire "solid" businesses for reasonable multiples of cash flow and then deploy resources to strengthen the infrastructure and systems to improve operations. These improvements may lead to a sale or IPO of an operating subsidiary at considerably higher valuations than the purchase price (as successfully demonstrated with the mid-2020 IPO of 1847 Goedeker on the NYSE American) and/or alternatively, an operating subsidiary may be held in perpetuity and contribute to EFSH's ability to pay regular and special dividends to shareholders.
Sharps Technology is a medical device and pharmaceutical packaging company specializing in the development and manufacturing of innovative drug delivery systems. The Company’s product lines focus on low waste and ultra-low waste syringe technologies that incorporate both passive and active safety features. These features protect front line healthcare workers from life-threatening needle stick injuries and protect the public from needle re-use. Sharps Technology has extensive expertise in specialized prefilled syringe systems and is on track to launch this new product line in Q4 2023. The Company has a manufacturing facility in Hungary and has partnered with Nephron Pharmaceuticals to expand its manufacturing capacity in the US.
SPI Energy is a global renewable energy company and provider of solar storage and electric vehicle (EV) solutions that was founded in 2006 in Roseville, California and is headquartered in McClellan Park, California. The Company has three core divisions: SolarJuice which has solar wholesale distribution, as well as residential solar and roofing installation and solar module manufacturing (Solar4America & SEM Wafertech), SPI Solar and Orange Power which operates a commercial & utility solar division, and the EdisonFuture/Phoenix Motor EV division. SolarJuice is the leader in renewable energy system solutions for residential and small commercial markets and has extensive operations in the Asia Pacific and North America markets. The SPI Solar commercial & utility solar division provides a full spectrum of EPC services to third party project developers, and develops, owns and operates solar projects that sell electricity to the grid in multiple regions, including the U.S., U.K., and Europe. Phoenix Motor is a leader in medium-duty commercial electric vehicles, and is developing EV charger solutions, electric pickup trucks, electric forklifts, and other EV products. SPI maintains global operations in North America, Australia, Asia and Europe and is also targeting strategic investment opportunities in fast growing green energy industries such as battery storage, charging stations, and other EVs which leverage the Company's expertise and substantial solar cash flow.
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
BioVie is a clinical-stage company developing what it believes will be transformative therapies to overcome unmet medical needs in neurodegeneration and liver disease. The Company is developing NE3107 for Alzheimer’s (AD) and Parkinson’s (PD) and BIV201 for refractory ascites and HRS-AKI.
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
Splash Beverage Group, an innovator in the beverage industry, owns a growing portfolio of alcoholic and non-alcoholic beverage brands including Copa di Vino wines by the glass, SALT naturally flavored tequilas, Pulpoloco Sangria, and TapouT performance hydration and recovery drinks and TapouT Cognitive Energy Drink. Splash’s strategy is to rapidly develop early-stage brands already in its portfolio as well as acquire and then accelerate brands that have high visibility or are innovators in their categories. Led by a management team that has built and managed some of the top brands in the beverage industry and led sales from product launch into the billions, Splash is rapidly expanding its brand portfolio and global distribution.
Splash Beverage Group, an innovator in the beverage industry, owns a growing portfolio of alcoholic and non-alcoholic beverage brands including Copa di Vino wines by the glass, SALT naturally flavored tequilas, Pulpoloco Sangria, and TapouT performance hydration and recovery drinks and TapouT Cognitive Energy Drink. Splash’s strategy is to rapidly develop early-stage brands already in its portfolio as well as acquire and then accelerate brands that have high visibility or are innovators in their categories. Led by a management team that has built and managed some of the top brands in the beverage industry and led sales from product launch into the billions, Splash is rapidly expanding its brand portfolio and global distribution.
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
Collective Mining | Corporate Presentation - May 2024
GENE Investor Deck May 2023
1. Genetic Technologies – Investor Webinar
The Future: Unlocking personalised preventative medicine
4 May, 2023
Authorised by the Board of Directors of Genetic Technologies Limited
ASX: GTG
NASDAQ: GENE
2. 2
World leading portfolio
2
Most comprehensive guideline driven
portfolio for human and animal health.
• Patented GeneType Multi Risk Test
• Non-Invasive Prenatal Testing (NIPT)
• Carrier screen testing
• Pharmacogenomics
• Oncogenetic diseases
• Pet care
Revenues anchored by our 3 brands to seize
a multi Billion-dollar opportunity.
3. [insert revenue structure
and agreement types]
Product list
[insert revenue structure
and agreement types]
Product list
[insert revenue structure
and agreement types]
Product list
3
Comprehensive genomics-based testings
via a multi-brand strategy
Direct to Consumer
Testing (DTC)
with no medical supervision
Consumer initiated
testing (CIT)
with medical supervision
Medical & Payer
Business to
Business (B2B)
Oncology – GTG
Cardiovascular
Prenatal NIPT
Carrier testing
Clinical & Molecular
Metabolic
Expanded Carrier testing & NIPT
Oncology – MultiTest
Cardiovascular – MultiTest
Metabolic – MultiTest
COVID Rick Test
Pharmacogenomics
Ancestry
Paternity
Health & Wellbeing
Pharmacogenetics
Animal
Drug testing
Relationship
DNA Storage
5. Snapshot and Achievements last 12 months
5
✓ 9 Tests NOW commercially available in the US
the geneType Multi-Risk test
✓ >100 medical practices on-boarded launching
the foundation of geneType Hubs in Australia
✓ Presentations by Dr Erika Spaeth at:
✓ ASCOGI Cancers Symposium Jan 2023
✓ San Antonio Breast Cancer Symposium,
✓ Precision Medicines leaders summit
✓ Precision Medicine World Conference
✓ Completed 2 Acquisitions
✓ NEW EasyDNA Website ready for launch
✓ NEW eCommerce Platform ready launch
✓ Launch Carrier Testing and Non-Invasive
Prenatal Tests (NIPT) into Europe
✓ Partnering in India with stud farms extending
paternity infrastructure into the equine industry
✓ Launch DNA storage solution in GTG NATA
approved facility
✓ Independently developed Budget Impact
Model (BIM) identifies US$1.4 billion dollars
in annual saving by ALVA 10
✓ 11 Active payer conversations
✓ Progress on US Payer meetings to enable
coverage across millions of lives
✓ Launch with A/Prof Charles Siles providing
immediate access to more than 1,000
referring primary care physicians and 15,000
patients annually in Australia
✓ Partnerships with Australian Breast Care
Centre and Dr Nicole Yap
✓ Launch of screening for breast cancer risk
with Prof Bruce Mann at Royal Women’s
Hospital in Melbourne
✓ 5 Peer reviewed publication in 6 months
✓ Published in PLOS ONE
✓ Published in Journal or Precision Medicine
✓ Published in European Journal of Cancer
prevention
✓ Published in journal Breast Cancer Research
and Treatment
✓ 25 Patents granted or pending
✓ 3 more papers under review
✓ Gained NATA and CMS-CLIA
accreditation and certification for 6
polygenic risk score tests
✓ Successful ARTG notification to TGA for
company IVDs for all tests on the multi-
risk test
GeneType commercialization EasyDNA & Affinity DNA Reimbursement activation
Partnerships Clinical Validity and IP Strategy Laboratory Capability
6. half-year ending December
31, 2021
Delivering Revenue and Growth – Q3 FY23
$1,967
$2,232
$4,626
$6,687
Q3 FY22 Q3 FY23 YTD FY22 YTD FY23
Cash Receipts (A$'000)
Strategic & Operational Highlights:
• March Quarter FY23 receipts A$4.22 million
• Cash receipts from customers A$2.2m +13% on last year;
• R&D Tax Incentive of A$1.96m was received in Q3 2023
• YTD receipts from customers A$6.69 million up 45% on prior year
• 7 consecutive qtrs. of growth on prior year
Q3 CASH RECEIPTS
A$2.2m
GROSS MARGIN
A$1.13m
March GROSS MARGIN
49% +2ppts
6
CASH BALANCE
A$10.5m*
*As at 31 March 2023
# All revenues for the period ‘21 & ‘22 are 'out of pocket' our strategy for reimbursement should become effective in 2023 FY
45%
Growth
on LY
• Launched Melanoma, Pancreatic Cancer and Atrial Fibrillation in U.S.
• Back to Back peer reviewed publications demonstrating Genetype for
Breast cancer identifies MORE at risk patients then the current
standards
• Presentations at ASCO Gi Cancers Symposium in San Francisco
7. Commercialisation of the geneType suite of multi-risk tests
Our FOCUS
Core ‘4’
Commercialisation of the geneType suite of multi-risk tests
Demonstrate clinical validity & clinical utility of geneType tests
Innovation: Next Generation of capability – Starting with Epigenetics
EasyDNA & Affinity DNA Revenue Growth: Tests, Channels. & Markets
Execute the B2B commercialisation of the geneType multi-risk test
7
8. NEW Comprehensive Breast and Ovarian Cancer test
Evaluates a woman’s risk of developing Breast and/or Ovarian Cancer in women 30 years+
• The test evaluates a women’s risk of developing Breast and/or Ovarian Cancer either from a hereditary genetic
mutation or from the far more common familial or sporadic cancer. (Announced Feb 3, 2023)
• GTG’s unique approach “appends” the detection of the 13 major “actionable” Breast and Ovarian cancer
susceptibility genes to the GeneType test platform.
• Advances the goal of providing population-based genetic screening where up to 85% of cancers diagnosed do
not have hereditary or family history
• Showcase at BRCA 2023 in Montreal
1 https://www.breastcancer.org/facts-statistics
Announcement - Globe Newswire
5% - Hereditary Cancer
with known pathogenic
variant BRCA1/2
85% - GeneType Patented
integrated Breast and
Ovarian Risk test
10% - Familial cancer with
no known pathogenic
variant
9. [insert revenue structure and agreement
types]
Product list
NEW – 9 Diseases now available in the US
GeneType can identify patients ’at risk’ before onset and aid in the early detection and treatment.
GeneType Risk assessment test for breast cancer has demonstrated improved early stage detection by
18% and saving approx. US$1.4B per annum4 for the US payer
9
Phase 1 Launch 2
GeneType Multi-
test covers
>70% of mortality
& morbidity
Phase 2 Launched – US March 20233
1. TGA, FDA and EU regulatory approval granted to the sponsor, DNA Genotek
2. Commercial availability in Australia and the US since Q1 CY2022
3. Commercial availability in the US and waiting on NATA Approval for Australia
4. Budget Impact Model prepared by Alva10
Breast Cancer
Colorectal Cancer
Prostate Cancer
Melanoma
Pancreatic Cancer
Ovarian Cancer
Oncology Cardiovascular
Atrial Fibrillation
Coronary Artery
Disease
Metabolic
Type 2 Diabetes
Diseases Areas
One report. Two risk scores.
Actionable results
10. Cancer Prevention Research
Validation of an abridged breast cancer risk prediction model
for the general population1. Spaeth EL, Dite GS, Hopper JL, Allman R.
European Journal of Cancer Prevention
A combined clinical and genetic model for predicting risk of
ovarian cancer2 Dite GS, Spaeth E, Murphy NM, Allman R.
Breast Cancer Research and Treatment
Validation of a breast cancer risk prediction model based on the
key risk factors: family history, mammographic density and
polygenic risk3 Allman R, Mu Y, Dite GS, Spaeth E, Hopper JL, Rosner BA.
NEW – 3 Peer Review Publications Released
Our Scientific team continues to achieve scientific publication milestones, with 3 publications
accepted in three peer-reviewed journals during the quarter
10
1. https://pubmed.ncbi.nlm.nih.gov/36862830/
2. https://pubmed.ncbi.nlm.nih.gov/36503897
3. https://pubmed.ncbi.nlm.nih.gov/36749458/
Guideline driven, Actionable results
3 NEW Peer
reviewed
Publications in
the latest Qtr
11. NEW Strategic Alliance with Qiagen
The alliance will establish and develop a ‘Centre of Excellence’ facility in Australia
QIAGEN will support the enhancement of GTG capabilities
through software, hardware, consumable and technical
solutions, including:
• Reagents and QIAGEN’s proprietary QCII software to
complete Next Generation Sequencing (NGS) validation
in house.
• The rollout will include QIAGEN’s QIAseq targeted DNA
Pro Sample to Insight solutions for NGS Oncology and
customized inhouse data analysis tools to provide
sample to result service for GTG customers
Announcement – Globe Newswire Feb 1 2023
12. [insert revenue
structure and
agreement types]
Product list
Medical & Payer
Business to
Business (B2B)
GeneType Priority Pathway to Market
Health Economic modeling completed by
ALVA10*
Certifying reimbursable testing platform:
BRCA test & LYNCH Syndrome test
A plan curated for: Payers / Insurers*
Primary Care Physicians, Specialists,
Surgeons, Concierge Medicine Groups
geneType Multi-test
NGS platforms with Germline, Carrier
Screening and NIPT
BRCA test & LYNCH Syndrome test
Revenue
Drivers
Partners
Products
* Corporates and Insurance market entry assessment in progress and Health Economic Model being completed by ALVA10. 12
Payer coverage is the key driver of revenues for geneType
Coverage from payers in the US will accelerate adoption of
geneType Risk Assessment Tests more widely
Budget Impact Model (BIM) demonstrates significant health &
economic benefits of implementing the geneType Breast
Cancer Risk Assessment Test
11 Active conversations with payer groups in the US
US Payers include:
• Humana – 17 million lives covered
• Aetna – 22.1 million live covered
• Independence Blue Cross – 3 million lives covered
Smaller payers such as employer groups have potential to
move quickly
BIM validates the benefits of implementing geneType
13. Economic Modeling in the US Payer System1
The economic benefit to the payers in the US is US$1.4B per annum
$73
US Payor system
will save per
patient per year
69% - 74%
overall increase in
women getting
screened
6.8%-9.2%
Supplemental
screening frequency
14.8% - 8.8%
Interval Cancers
drop
57% - 67%
Early-stage cancer
detection
1 Corporates and Insurance market entry assessment - Health Economic Model completed by ALVA10 May 2022.
3.6% in annual savings to a payer system in the screening and treatment of
breast cancer.
13
14. [insert revenue structure and
agreement types]
Product list
[insert revenue structure and
agreement types]
Product list
PHASE 1
Brand Re-Ignition
DTC - Growth strategy for EasyDNA
Brand Refresh
Multi-brand Portfolio
EasyDNA Brand Refresh
Test Rationalization
Website Refresh
Website Development
First-party data collection
Targeted Messaging
Improve User experience and
engagement
PHASE 2
Revenue and Growth Focus
Improved Lead Gen
Google Ads
Facebook Ads
Content & Email Marketing
Influencer Marketing &
Testimonials
New Sales Channels
Amazon store front
Target B2B customer
segments
New Markets
14
18. Dr. Lindsay Wakefield
MBBS
Non – Executive Director
Mr. Peter Rubinstein
BEc, LLB
Chairman
Non – Executive Director
Dr. Jerzy “George”
Muchnicki
MBBS
Non-Executive Director
Mr Nick Burrows
B.Comm, FAICD, FCA,
FGIA, FTIA, F Fin
Non – Executive Director
Simon Morriss
GAICD
Chief Executive Officer
Richard Allman
BSc, PhD
Scientific Advisor
Tony Di Pietro
B. Comm, CA, AGIA, MAICD
CFO & Company Secretary
Carl Stubbings
Chief Commercial
Officer
Erika Spaeth
PhD
Director of Clinical &
Scientific Affairs
Board and Management:
Sales and Scientific expertise leading GTG
18
19. Professor Jon Emery
MBBCh MA DPhil FRACGP MRCGP
Research & Education Lead,
Primary Care Integration,
Victorian Comprehensive Cancer
Centre Herman Chair of Primary
Care Cancer Research,
University of Melbourne
Professor Finlay Macrae AO
MBBS, MD, FRACP, FRCP, AGAF
MWGO is Principal Fellow and
Professor, Department of
Medicine, University of
Melbourne, and Head of
Colorectal Medicine and
Genetics, The Royal Melbourne
Hospital
Ora K. Gordon, M.D.
MD, MS, FACMG
Regional Medical Director,
Center for Clinical Genetics &
Genomics. Clinical Director, PSJH
Population Health Genomics
Program. Chair, Integrated
Network Cancer Program,
Professor of Genetics, St John
Cancer Institute
Strong Scientific Leadership:
Advisory Board
A.Prof Ron Dick
MBBS, FRACP, FCSANZ,
Chairman of Cardiovascular
Institute at Epworth Healthcare,
an Honorary Cardiologist at the
Alfred Hospital and Bendigo
Healthcare Group.
Completed his MBBS in 1979 and
became a Fellow of the
Australian College of Physicians
in 1986. His interventional
cardiology fellowship was from
the University of Michigan
Medical Centre USA.
19
20. • Net cash outflow of A$7.2 million for the nine months to 31 March 2023.
We continue to grow EasyDNA and Affinity DNA brand sales and
develop and commercialise our geneType tests
• Cash reserves will be directed to:
• to support the commercialisation of the GeneType Multi Risk
test through the B2B channels with payers, insurers and
employers in the United States and expand into Europe;
• to drive new market opportunities in reimbursable categories
by leveraging our strategic relationship with QIAGEN;
• for funding product research and development;
• to increase our sales and marketing presences and drive of its
tests via the consumer-initiated testing platforms;
• to execute the go to market, sales and marketing to launch the
Comprehensive Hereditary Breast and Ovarian Cancer Risk
Test as part of our germline genetic testing division; and
• for other working capital and general corporate purposes.
A$’000 31-March-23 31-March-22 Change
Net operating cashflow (7,249) (6,152) -18%
Receipts from customers 6,687 4,626 45%
Cash 10,481 11,350 -8%
1 Based on cashflow projections
20
Financial Overview
21. BNY Mellon, 71%
Board &
Management ,
5%,
Other, 24%
BNY Mellon Board & Management Other
Top 50 share registry breakdown
Financial Information
Share price (AUD) as at 25 April 2023 0.3c
ADR price (USD) as at 25 February 2023 $1.06
Ord Shares on Issue (M) 11,542
ASX 52-week trading (AUD low/high) 0.2/1.3c
Nasdaq 52-week trading (USD low/high) 0.86/1.82
Market Cap (A$M/US$M) 34.6/19.0
Cash at 31 March 2023 A$10.5m
Cash at 30 June 2022 A$11.7m
Debt (30 June 2022 and 31 March 2023) nil
Dual Listed on the ASX and Nasdaq
Corporate Overview
21
22. 4 Patents granted in the US
• Patent No: US 11,257,569, Methods of
assessing risk of developing a severe
response to Coronavirus infection
• Patent No: US 11,072,830, Methods for breast
cancer risk assessment
• Patent No: US 10,683,549, Methods for
assessing risk of developing breast cancer
• Patent No: US 10,920,279, Methods for
assessing risk of developing breast cancer
2 Patents granted in PRC (China & HK)
• Patent No. 201080033130.5 Methods for Breast
Cancer Risk Assessment
• Patent No. 201580063966.2 Methods for
assessing risk of developing breast cancer
9 Patent families pending
• Breast cancer risk assessment
• Methods for assessing risk of developing prostate cancer
• Methods for assessing risk of developing ovarian cancer
• Methods of assessing risk of developing a severe response to
Coronavirus infection
• Methods of assessing risk of developing a disease
• Methods for assessing risk of developing breast cancer
• Improved methods for assessing risk of developing breast
cancer
• Methods of assessing risk of developing breast cancer
• Methods for assessing risk of developing colorectal cancer
Our Intellectual Property
22
* Patents granted are specific to the GeneType portfolio of products
23. Defined Terms
Common Complex Diseases (CCP) – A complex disease is caused by the interaction of multiple genes and environmental factors. Complex diseases are also called multifactorial. Examples of common complex diseases include
cancer and heart disease.
Polygenic risk score - a number associated with one’s disease risk based on the aggregated effects of individual risk variants through a multiplicative algorithm.
Variant - Single Nucleotide polymorphism (SNP), an alteration in DNA that may be a common or rare event.
Genomic - pertaining to function of genetics from structure to relationship between genetic events.
Genetic - pertaining to a gene.
GWAS - genome-wide association studies are large population level studies which enable scientists to identify genes and genetic markers involved in human disease. This method searches the genome for SNPs that occur
more frequently in people with a particular disease than in people without the disease. Each study can look at hundreds or many thousands of SNPs at the same time. Researchers use data from this type of study to pinpoint
genetic variations that may contribute to a person’s risk of developing a certain disease.
SNP - Single nucleotide polymorphisms, frequently called SNPs (pronounced “snips”), are the most common type of genetic variation among people. Each SNP represents a difference in a single DNA building block, called a
nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA.
Serious Disease Risk (SDR) - Risk associated with acquiring COVID-19 and requiring hospitalisation withs its associated morbidities and mortalities.
Germline Testing – Germline testing is done on cells that do not have cancer. It is done to see if a person has a gene mutation that is known to increase the risk of developing cancers and other health problems. This test uses
cells (such as blood or skin cells) that do not have any cancer cells. Germline mutations can sometimes be passed down from parents.
Clinical Laboratory Improvement Amendments (CLIA) - Regulates laboratory testing and require clinical laboratories to be certified by the Center for Medicare and Medicaid Services (CMS) before they can accept human
samples for diagnostic testing
National Association of Testing Authorities (NATA) - the authority responsible for the accreditation of laboratories, inspection bodies, calibration services, producers of certified reference materials and proficiency testing
scheme providers throughout Australia. It is also Australia's compliance monitoring authority for the OECD Principles of GLP. NATA provides independent assurance of technical competence through a proven network of
best practice industry experts for customers who require confidence in the delivery of their products and services.
Next Generation Sequencing (NGS) – Next-generation sequencing (NGS), also known as high-throughput sequencing, is the catch-all term used to describe a number of different modern sequencing technologies. These
technologies allow for sequencing of DNA and RNA much more quickly and cheaply than the previously used Sanger sequencing, and as such revolutionised the study of genomics and molecular biology.
Laboratory Developed Tests (LDT) – A type of in vitro diagnostic test that is designed, manufactured and used within a single laboratory.
Consumer Initiated Tests (CIT) - laboratory testing that is initiated by the consumer without a physician order but reviewed and communicated back to the consumer via a physician.
Direct to Consumer (DTC) – laboratory testing that is initiated by the consumer without a physician order. The results are reported back directly to the consumer.
Health Care Professionals (HCP) – physician, GP, or specialist authorized to receive the patient results
23