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Cornea, Chalazia &
Cross-Linking
DR C PETSOGLOU
Tues 21st Oct 2014 UPDATE 1
Cross-Linking
AIM: Prevent progressive corneal ectasia
WHO: Keratoconus, kerectasia, pellucid
marginal degeneration
WHEN: Documented change in cornea
◦ Increase in keratometry readings
◦ Change in refraction
◦ NOT in every keratoconus or newly diagnosed
patient yet!
ADVISE:
◦ Very painful for 24hrs!!!!
◦ 90% halt progression
◦ Up to 50% may show some improvement in BCVA,
Tues 21st Oct 2014 UPDATE 2
Tues 21st Oct 2014 UPDATE 3
Preop: UCVA 6/18 BCVA 6/9
Postop: UCVA 6/9 BCVA 6/6
Audit Results
Of 15 Eyes at least 6 months follow up:
◦ 3 Improved > 1D (1.6, 2.7, 3.5)
◦ 4 Improved by 1D
◦ 4 stayed the same +/- 0.5D
◦ 3 Worsened (1.5, 1.8, 3.0)
◦ 80% Improved or stable
◦ 20% Progressed
Tues 21st Oct 2014 UPDATE 4
0
10
20
30
40
50
60
AVERAGEKERATOMETRY
Audit 15 Patients
Preop Post-Op
Chalazia
Tues 21st Oct 2014 UPDATE 5
Meibomian gland cyst / Infected = Hordoleum
57% pts >19yo for excision have Rosacea
◦ Lempert SL Arch Ophthal 1979; 97: 1652-3
Low Serum Vitamin A in Children (China study)
◦ Chen L et al Am J Ophthal 2014; 157(5):1103-8
MANAGEMENT:
◦ Heat and Massage
◦ Oral Antibiotics if infected: Doxycycline 50mg bd or
Dicloxicillin 500mg qid
◦ Topical Antibiotic No benefit
◦ One RCT: H+M, Incision, Triamcinolone injection
◦ 3 weeks: H+M 46%, Incision 87%, Triamcinolone 84%
◦ Clinical and Experimental Ophthalmology, 2007;35(8):706- 12
Chalazia
Demodex brevis story
High prevalence of demodex brevis infestation in chalazia.
Liang L. et al Am J Ophthal. 157(2):342-348.e1, 2014 Feb
Skin Mite- Increasing prevalence with age
Classic teaching – NOT Pathogenic
DIAGNOSE: Eyelash epilation and view under microscope
TREATMENT:
◦ 5 drops tea tree oil shampoo in ½ cup boiled water
◦ 1:4 tea tree oil with olive oil as scrub
BUT: Some doubts still remain!
Tues 21st Oct 2014 UPDATE 6
Cornea
Lions NSW Eye Bank Waitlist for Corneal Transplants
Wait time <3 Months
WHY?
1. Organ Culture
2. Scheduled Surgery
3. 5 Coordinators
4. Hospice Planning
Tues 21st Oct 2014 UPDATE 7
466472461
448440
407
351
320
285278
250
263
234223
200
227
204192181170
155151160161162
176178167162
0
50
100
150
200
250
300
350
400
450
500
Jan
Feb
Mar
Apr
May
June
Jul
Aug
Sept
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
June
July
Aug
Sept
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
2012 2013 2014
EBAANZ definition

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Focus on the three C's - Cornea, chalazion & Cross Linking

  • 1. Cornea, Chalazia & Cross-Linking DR C PETSOGLOU Tues 21st Oct 2014 UPDATE 1
  • 2. Cross-Linking AIM: Prevent progressive corneal ectasia WHO: Keratoconus, kerectasia, pellucid marginal degeneration WHEN: Documented change in cornea ◦ Increase in keratometry readings ◦ Change in refraction ◦ NOT in every keratoconus or newly diagnosed patient yet! ADVISE: ◦ Very painful for 24hrs!!!! ◦ 90% halt progression ◦ Up to 50% may show some improvement in BCVA, Tues 21st Oct 2014 UPDATE 2
  • 3. Tues 21st Oct 2014 UPDATE 3 Preop: UCVA 6/18 BCVA 6/9 Postop: UCVA 6/9 BCVA 6/6
  • 4. Audit Results Of 15 Eyes at least 6 months follow up: ◦ 3 Improved > 1D (1.6, 2.7, 3.5) ◦ 4 Improved by 1D ◦ 4 stayed the same +/- 0.5D ◦ 3 Worsened (1.5, 1.8, 3.0) ◦ 80% Improved or stable ◦ 20% Progressed Tues 21st Oct 2014 UPDATE 4 0 10 20 30 40 50 60 AVERAGEKERATOMETRY Audit 15 Patients Preop Post-Op
  • 5. Chalazia Tues 21st Oct 2014 UPDATE 5 Meibomian gland cyst / Infected = Hordoleum 57% pts >19yo for excision have Rosacea ◦ Lempert SL Arch Ophthal 1979; 97: 1652-3 Low Serum Vitamin A in Children (China study) ◦ Chen L et al Am J Ophthal 2014; 157(5):1103-8 MANAGEMENT: ◦ Heat and Massage ◦ Oral Antibiotics if infected: Doxycycline 50mg bd or Dicloxicillin 500mg qid ◦ Topical Antibiotic No benefit ◦ One RCT: H+M, Incision, Triamcinolone injection ◦ 3 weeks: H+M 46%, Incision 87%, Triamcinolone 84% ◦ Clinical and Experimental Ophthalmology, 2007;35(8):706- 12
  • 6. Chalazia Demodex brevis story High prevalence of demodex brevis infestation in chalazia. Liang L. et al Am J Ophthal. 157(2):342-348.e1, 2014 Feb Skin Mite- Increasing prevalence with age Classic teaching – NOT Pathogenic DIAGNOSE: Eyelash epilation and view under microscope TREATMENT: ◦ 5 drops tea tree oil shampoo in ½ cup boiled water ◦ 1:4 tea tree oil with olive oil as scrub BUT: Some doubts still remain! Tues 21st Oct 2014 UPDATE 6
  • 7. Cornea Lions NSW Eye Bank Waitlist for Corneal Transplants Wait time <3 Months WHY? 1. Organ Culture 2. Scheduled Surgery 3. 5 Coordinators 4. Hospice Planning Tues 21st Oct 2014 UPDATE 7 466472461 448440 407 351 320 285278 250 263 234223 200 227 204192181170 155151160161162 176178167162 0 50 100 150 200 250 300 350 400 450 500 Jan Feb Mar Apr May June Jul Aug Sept Oct Nov Dec Jan Feb Mar Apr May June July Aug Sept Oct Nov Dec Jan Feb Mar Apr May 2012 2013 2014 EBAANZ definition