This document summarizes a seminar discussing the challenges of local governance and the relationship between science and development policy. The seminar will have two parts, with the first exploring the incentives and implications of networked governance involving multiple stakeholders. The second part will discuss how scientific knowledge can better inform development strategies in the new policy context of building smart, sustainable and inclusive growth, while also examining why science-based policies have sometimes fallen short of expectations in influencing development trajectories. The seminar aims to further debates around leadership challenges in complex governance systems and whether the current policy climate enhances the potential for science to more decisively shape societal progress.