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Cancer
Cancer is a condition where cells in a specific part of the body grow and
reproduce uncontrollably. The cancerous cells can invade and destroy
surrounding healthy tissue, including organs. Cancer sometimes begins in one
part of the body before spreading to other areas.
Signs and symptoms
When cancer begins, it produces no symptoms. Signs and symptoms
appear as the mass grows or ulcerates. The findings that result depend on the
cancer's type and location. Few symptoms are specific. Many frequently occur
in individuals who have other conditions. Cancer can be difficult to diagnose
and can be considered a "great imitator."
People may become anxious or depressed post-diagnosis. The risk of
suicide in people with cancer is approximately double.
Cause
The majority of cancers, some 90–95% of cases, are due to genetic
mutations from environmental and lifestyle factors. The remaining 5–10% are
due to inherited genetics. Environmental refers to any cause that is not
inherited, such as lifestyle, economic, and behavioral factors and not merely
pollution. Common environmental factors that contribute to cancer death
include tobacco use (25–30%), diet and obesity (30–35%), infections
(15–20%), radiation (both ionizing and non-ionizing, up to 10%), lack of
physical activity, and pollution. Psychological stress does not appear to be a
risk factor for the onset of cancer, though it may worsen outcomes in those
who already have cancer.
It is not generally possible to prove what caused a particular cancer
because the various causes do not have specific fingerprints, however factors
that may have contributed to the development of cancer can be transmissible;
such as oncoviruses like hepatitis B, Epstein-Barr virus and HIV.
Chemicals
Diet and exercise
Infection
Radiation
Heredity
Physical agents
Hormones
Autoimmune diseases
Genetics
Epigenetics
Metastasis
Metabolism
Classification
Cancers are classified by the type of cell that the tumor cells resemble and
is therefore presumed to be the origin of the tumor. These types include:
Carcinoma: Cancers derived from epithelial cells. This group includes
many of the most common cancers and include nearly all those in the breast,
prostate, lung, pancreas and colon.
Sarcoma: Cancers arising from connective tissue (i.e. bone, cartilage, fat,
nerve), each of which develops from cells originating in mesenchymal cells
outside the bone marrow.
Lymphoma and leukemia: These two classes arise from hematopoietic
(blood-forming) cells that leave the marrow and tend to mature in the lymph
nodes and blood, respectively.
Germ cell tumor: Cancers derived from pluripotent cells, most often
presenting in the testicle or the ovary (seminoma and dysgerminoma,
respectively).
Blastoma: Cancers derived from immature "precursor" cells or embryonic
tissue.
Prevention
Cancer prevention is defined as active measures to decrease cancer risk.
The vast majority of cancer cases are due to environmental risk factors. Many
of these environmental factors are controllable lifestyle choices. Thus, cancer
is generally preventable. Between 70% and 90% of common cancers are due
to environmental factors and therefore potentially preventable.
Greater than 30% of cancer deaths could be prevented by avoiding risk factors
including: tobacco, excess weight/obesity, poor diet, physical inactivity, alcohol,
sexually transmitted infections and air pollution. Further, poverty could be
considered as an indirect risk factor in human cancers. Not all environmental
causes are controllable, such as naturally occurring background radiation and
cancers caused through hereditary genetic disorders and thus are not
preventable via personal behavior.
Dietary: Eat Healthy and Get Active
Medication: Get Screened
Vaccination: HPV Prevention
Can Cancer Be Cured?
Whether a person’s cancer can be cured depends on the type and stage
of the cancer, the type of treatment they can get, and other factors. Some
cancers are more likely to be cured than others. But each cancer needs to be
treated differently. There isn’t one cure for cancer.
Cure versus remission
A cure means that the cancer has gone away with treatment, no more
treatment is needed, and the cancer is not expected to come back. It’s rare
that a doctor can be sure that cancer will never come back. In most cases it
takes time to know if the cancer might come back. But, the longer a person is
cancer free, the better the chance that the cancer will not come back. More
often, when treatment appears to be successful, doctors will say the cancer is
“in remission,” rather than “cured.”
Reference:
1, "Cancer – Signs and symptoms". NHS Choices. Archived from the original
on 8 June 2014. Retrieved 10 June 2014.
2, "Cancer". World Health Organization. 12 September 2018. Retrieved 19
December 2018.
3,"Targeted Cancer Therapies". cancer.gov. National Cancer Institute. 26
February 2018. Retrieved 28 March 2018.
4,"SEER Stat Fact Sheets: All Cancer Sites". National Cancer Institute.
Archived from the original on 26 September 2010. Retrieved 18 June 2014.

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Feiyuebio research-Cancer.pdf

  • 1. Cancer Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one part of the body before spreading to other areas. Signs and symptoms When cancer begins, it produces no symptoms. Signs and symptoms appear as the mass grows or ulcerates. The findings that result depend on the cancer's type and location. Few symptoms are specific. Many frequently occur in individuals who have other conditions. Cancer can be difficult to diagnose and can be considered a "great imitator." People may become anxious or depressed post-diagnosis. The risk of suicide in people with cancer is approximately double. Cause The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics. Environmental refers to any cause that is not inherited, such as lifestyle, economic, and behavioral factors and not merely pollution. Common environmental factors that contribute to cancer death
  • 2. include tobacco use (25–30%), diet and obesity (30–35%), infections (15–20%), radiation (both ionizing and non-ionizing, up to 10%), lack of physical activity, and pollution. Psychological stress does not appear to be a risk factor for the onset of cancer, though it may worsen outcomes in those who already have cancer. It is not generally possible to prove what caused a particular cancer because the various causes do not have specific fingerprints, however factors that may have contributed to the development of cancer can be transmissible; such as oncoviruses like hepatitis B, Epstein-Barr virus and HIV. Chemicals Diet and exercise Infection Radiation Heredity Physical agents Hormones Autoimmune diseases Genetics Epigenetics Metastasis Metabolism Classification Cancers are classified by the type of cell that the tumor cells resemble and is therefore presumed to be the origin of the tumor. These types include: Carcinoma: Cancers derived from epithelial cells. This group includes many of the most common cancers and include nearly all those in the breast,
  • 3. prostate, lung, pancreas and colon. Sarcoma: Cancers arising from connective tissue (i.e. bone, cartilage, fat, nerve), each of which develops from cells originating in mesenchymal cells outside the bone marrow. Lymphoma and leukemia: These two classes arise from hematopoietic (blood-forming) cells that leave the marrow and tend to mature in the lymph nodes and blood, respectively. Germ cell tumor: Cancers derived from pluripotent cells, most often presenting in the testicle or the ovary (seminoma and dysgerminoma, respectively). Blastoma: Cancers derived from immature "precursor" cells or embryonic tissue. Prevention Cancer prevention is defined as active measures to decrease cancer risk. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Thus, cancer is generally preventable. Between 70% and 90% of common cancers are due to environmental factors and therefore potentially preventable. Greater than 30% of cancer deaths could be prevented by avoiding risk factors including: tobacco, excess weight/obesity, poor diet, physical inactivity, alcohol, sexually transmitted infections and air pollution. Further, poverty could be considered as an indirect risk factor in human cancers. Not all environmental causes are controllable, such as naturally occurring background radiation and cancers caused through hereditary genetic disorders and thus are not preventable via personal behavior. Dietary: Eat Healthy and Get Active Medication: Get Screened Vaccination: HPV Prevention Can Cancer Be Cured?
  • 4. Whether a person’s cancer can be cured depends on the type and stage of the cancer, the type of treatment they can get, and other factors. Some cancers are more likely to be cured than others. But each cancer needs to be treated differently. There isn’t one cure for cancer. Cure versus remission A cure means that the cancer has gone away with treatment, no more treatment is needed, and the cancer is not expected to come back. It’s rare that a doctor can be sure that cancer will never come back. In most cases it takes time to know if the cancer might come back. But, the longer a person is cancer free, the better the chance that the cancer will not come back. More often, when treatment appears to be successful, doctors will say the cancer is “in remission,” rather than “cured.” Reference: 1, "Cancer – Signs and symptoms". NHS Choices. Archived from the original on 8 June 2014. Retrieved 10 June 2014. 2, "Cancer". World Health Organization. 12 September 2018. Retrieved 19 December 2018. 3,"Targeted Cancer Therapies". cancer.gov. National Cancer Institute. 26 February 2018. Retrieved 28 March 2018. 4,"SEER Stat Fact Sheets: All Cancer Sites". National Cancer Institute. Archived from the original on 26 September 2010. Retrieved 18 June 2014.