Talk multiscale analysis of ionic solutions is unavoidableBob Eisenberg
Ions in channels and solutions control most living functions. Analysis in atomic detail is needed, but so is prediction of functions on the macroscopic scale. Computational electronics has solved similar issues and we all benefit from the computational devices it provides us. These slides show how a similar approach can be used, and is necessary in my view, for ions solutions and biological systems, most notably in ion channels
1. Mobile sensors from phones provide more accurate and extensive data than human senses, and are improving with new sensors and efficiency gains.
2. Historically, humans have measured and recorded data about the world through various means, but mobile sensors now allow measurement of things like temperature, sentiment, and human behavior on a vast scale.
3. OpenSignal is building sensor networks using data from over 7 million phones to analyze outdoor temperature, public opinion, mobile internet speeds and how much people use their phones throughout the day, demonstrating how mobile sensors can be utilized for scientific observation and research.
Device approach to biology and engineeringBob Eisenberg
Device Approach to Biology (and Engineering)
The goal of biological research is often more to control than to understand. Devices in biology (like ion channels) control individual functions just as they do in our technology. Study of control requires a multiscale approach because a handful of atoms, moving in 10-15 sec, control biological functions extending meters and taking seconds. Structural biology and molecular dynamics are essential (and beautiful!) parts of this hierarchy, but so are the functions themselves, and the electric field equations that link structure and function on all scales from atoms to nerve cells. Analyzing biological systems as devices is usually successful, and almost always productive.
Talk device approach to biology march 29 1 2015Bob Eisenberg
Device Approach to Biology (and Engineering)
The goal of biological research is often more to control than to understand. Devices in biology (like ion channels) control individual functions just as they do in our technology. Study of control requires a multiscale approach because a handful of atoms, moving in 10-15 sec, control biological functions extending meters and taking seconds. Structural biology and molecular dynamics are essential (and beautiful!) parts of this hierarchy, but so are the functions themselves, and the electric field equations that link structure and function on all scales from atoms to nerve cells. Analyzing biological systems as devices is usually successful, and almost always productive.
We carry take our mobiles with us wherever we go, we keep them fuelled with energy and, typically, there's no other object we own so sensitive to our surroundings.
This makes mobiles ideal for capturing a rich dataset about human activities and the man-made & natural environment. In fact mobiles are far more capable than humans as measurement tools - or sensors.
Mobiles are getting more plentiful, being equipped with more sensor hardware, and that hardware is operating at an entirely new level of efficiency. Taken together, this means mobile sensors could become the predominant datasource of the 21st century.
At OpenSignal and WeatherSignal we're exploring the ways mobile sensors can be aggregated into sensor networks, by creating engaging apps and communities of contributors. We're applying big data analysis to make sense of the readings collected.
We believe the sensors in phones constitute the most powerful scientific apparatus in the world. What experiments would you run?
The document discusses how to sign an email message for identity verification and non-repudiation. It describes adding the 'SEM' app to INSTALLED_APPS, configuring DEFAULT_CHARSET and AUTH_CERT settings, and using the SignedEmailMessage class from the SEMail module instead of the regular EmailMessage class to send a signed message. The SignedEmailMessage requires a from_key and from_cert to attach a digital signature to the message.
Talk two electro dynamics and ions in chemistryBob Eisenberg
The universal nature of electrodynamics and the strength of the electric field needs to be incoporated into chemical theory and thinking. The law of mass action for example is incompatible with continuity of current and thus with Maxwell's equations. Maxwell's equations are accurate from unimaginably small to unimaginably large dimensions with immeasurable accuracy. Violations of Maxwell's equations have large effects because the electric field is so large. Methods are shown to incorporate these realities into chemical descriptions.
Talk multiscale analysis of ionic solutions is unavoidableBob Eisenberg
Ions in channels and solutions control most living functions. Analysis in atomic detail is needed, but so is prediction of functions on the macroscopic scale. Computational electronics has solved similar issues and we all benefit from the computational devices it provides us. These slides show how a similar approach can be used, and is necessary in my view, for ions solutions and biological systems, most notably in ion channels
1. Mobile sensors from phones provide more accurate and extensive data than human senses, and are improving with new sensors and efficiency gains.
2. Historically, humans have measured and recorded data about the world through various means, but mobile sensors now allow measurement of things like temperature, sentiment, and human behavior on a vast scale.
3. OpenSignal is building sensor networks using data from over 7 million phones to analyze outdoor temperature, public opinion, mobile internet speeds and how much people use their phones throughout the day, demonstrating how mobile sensors can be utilized for scientific observation and research.
Device approach to biology and engineeringBob Eisenberg
Device Approach to Biology (and Engineering)
The goal of biological research is often more to control than to understand. Devices in biology (like ion channels) control individual functions just as they do in our technology. Study of control requires a multiscale approach because a handful of atoms, moving in 10-15 sec, control biological functions extending meters and taking seconds. Structural biology and molecular dynamics are essential (and beautiful!) parts of this hierarchy, but so are the functions themselves, and the electric field equations that link structure and function on all scales from atoms to nerve cells. Analyzing biological systems as devices is usually successful, and almost always productive.
Talk device approach to biology march 29 1 2015Bob Eisenberg
Device Approach to Biology (and Engineering)
The goal of biological research is often more to control than to understand. Devices in biology (like ion channels) control individual functions just as they do in our technology. Study of control requires a multiscale approach because a handful of atoms, moving in 10-15 sec, control biological functions extending meters and taking seconds. Structural biology and molecular dynamics are essential (and beautiful!) parts of this hierarchy, but so are the functions themselves, and the electric field equations that link structure and function on all scales from atoms to nerve cells. Analyzing biological systems as devices is usually successful, and almost always productive.
We carry take our mobiles with us wherever we go, we keep them fuelled with energy and, typically, there's no other object we own so sensitive to our surroundings.
This makes mobiles ideal for capturing a rich dataset about human activities and the man-made & natural environment. In fact mobiles are far more capable than humans as measurement tools - or sensors.
Mobiles are getting more plentiful, being equipped with more sensor hardware, and that hardware is operating at an entirely new level of efficiency. Taken together, this means mobile sensors could become the predominant datasource of the 21st century.
At OpenSignal and WeatherSignal we're exploring the ways mobile sensors can be aggregated into sensor networks, by creating engaging apps and communities of contributors. We're applying big data analysis to make sense of the readings collected.
We believe the sensors in phones constitute the most powerful scientific apparatus in the world. What experiments would you run?
The document discusses how to sign an email message for identity verification and non-repudiation. It describes adding the 'SEM' app to INSTALLED_APPS, configuring DEFAULT_CHARSET and AUTH_CERT settings, and using the SignedEmailMessage class from the SEMail module instead of the regular EmailMessage class to send a signed message. The SignedEmailMessage requires a from_key and from_cert to attach a digital signature to the message.
Talk two electro dynamics and ions in chemistryBob Eisenberg
The universal nature of electrodynamics and the strength of the electric field needs to be incoporated into chemical theory and thinking. The law of mass action for example is incompatible with continuity of current and thus with Maxwell's equations. Maxwell's equations are accurate from unimaginably small to unimaginably large dimensions with immeasurable accuracy. Violations of Maxwell's equations have large effects because the electric field is so large. Methods are shown to incorporate these realities into chemical descriptions.
Electricity is different august 16 1 2016 with doiBob Eisenberg
Charges are everywhere because most atoms are charged. Chemical bonds are formed by electrons with their charge. Charges move and interact according to Maxwell's equations in space and in atoms where the equations of electrodynamics are embedded in Schrödinger's equation as the potential. Maxwell's equations are universal, valid inside atoms and between stars from times much shorter than those of atomic motion (0.1 femtoseconds) to years (32 mega-seconds). Maxwell's equations enforce the conservation of current. Analysis shows that the electric field can take on whatever value is needed to ensure conservation of current. The properties of matter rearrange themselves to satisfy Maxwell's equations and conservation of current. Conservation of current is as universal as Maxwell's equations themselves. Yet equations of electrodynamics find little place in the literature of material physics, chemistry, or biochemistry. Kinetic models of chemistry and Markov treatments of atomic motion are ordinary differential equations in time and do not satisfy conservation of current unless modified significantly. Systems at equilibrium, without macroscopic flow, have thermal fluctuating currents that are conserved according to the Maxwell equations although their macroscopic averages are zero. The macroscopic consequences of atomic scale fluctuating thermal currents are not known but are likely to be substantial because of the nonlinear interactions in systems like these, in which 'everything interacts with everything else'.
The document provides guidance on IELTS writing tasks 1 and 2. It discusses the different types of topics that may appear, including argument, persuasion, and narrative. It emphasizes the importance of structure, with introductions, body paragraphs, and conclusions. It also highlights differences in how to approach and structure responses for argument versus persuasion topics. Key points include presenting both sides of an issue for arguments and stating your opinion upfront for persuasions. The document concludes by offering samples of topic questions and outlines for responding to them appropriately.
1. The document discusses different taxonomic classifications including alpha, beta, and gamma taxonomy. It also mentions phylogenetic and neo taxonomy.
2. Several plant families are listed including Brassicaceae, Boraginaceae, and Asteraceae. Characteristics of different plant families like flower structure and leaf arrangements are provided.
3. Examples of plant species are given, such as Sagittaria cuneata, Alisma triviale, and Arenga australasica. Traits of monocots like herbaceous stems and lack of endosperm are mentioned.
Apple was founded in 1976 by Steve Jobs, Steve Wozniak, and Ronald Wayne. It started as a computer company and is now a multinational technology company that produces consumer electronics, computer software, and online services. Apple's major products include the iPhone, iPad, Mac computers, iPod, and Apple's online stores like the iTunes Store. Apple has become the largest publicly traded company in the world by market capitalization and is the largest technology company by revenue and profit.
The document summarizes key aspects of the Sale of Goods Act 1930 in India. It defines important terms like sale, agreement to sell, goods, and conditions vs warranties. It also outlines implied conditions and warranties, as well as rules around transfer of property, delivery, unpaid sellers' rights, and auction sales. The Act establishes important distinctions between different types of contracts and rights/obligations of buyers and sellers.
The document discusses key aspects of India's first five-year plan presented by Jawahar Lal Nehru after independence. It allocates funds to sectors like agriculture, transportation and aims for GDP growth of 2.1% which was surpassed at 3.6%. Infrastructure projects like dams were also initiated. National income grew due to factors like increased crop yields but population growth reduced the per capita income growth.
Perang Dunia I adalah perang global yang terjadi di Eropa antara tahun 1914-1918 yang melibatkan sekutu seperti Inggris, Prancis, Rusia melawan kekuatan poros seperti Jerman, Austria-Hongaria. Konflik ini menewaskan lebih dari 9 juta tentara dan mengakhiri kekuasaan empayar-empayar besar seperti Jerman dan Rusia.
Electricity is different august 16 1 2016 with doiBob Eisenberg
Charges are everywhere because most atoms are charged. Chemical bonds are formed by electrons with their charge. Charges move and interact according to Maxwell's equations in space and in atoms where the equations of electrodynamics are embedded in Schrödinger's equation as the potential. Maxwell's equations are universal, valid inside atoms and between stars from times much shorter than those of atomic motion (0.1 femtoseconds) to years (32 mega-seconds). Maxwell's equations enforce the conservation of current. Analysis shows that the electric field can take on whatever value is needed to ensure conservation of current. The properties of matter rearrange themselves to satisfy Maxwell's equations and conservation of current. Conservation of current is as universal as Maxwell's equations themselves. Yet equations of electrodynamics find little place in the literature of material physics, chemistry, or biochemistry. Kinetic models of chemistry and Markov treatments of atomic motion are ordinary differential equations in time and do not satisfy conservation of current unless modified significantly. Systems at equilibrium, without macroscopic flow, have thermal fluctuating currents that are conserved according to the Maxwell equations although their macroscopic averages are zero. The macroscopic consequences of atomic scale fluctuating thermal currents are not known but are likely to be substantial because of the nonlinear interactions in systems like these, in which 'everything interacts with everything else'.
The document provides guidance on IELTS writing tasks 1 and 2. It discusses the different types of topics that may appear, including argument, persuasion, and narrative. It emphasizes the importance of structure, with introductions, body paragraphs, and conclusions. It also highlights differences in how to approach and structure responses for argument versus persuasion topics. Key points include presenting both sides of an issue for arguments and stating your opinion upfront for persuasions. The document concludes by offering samples of topic questions and outlines for responding to them appropriately.
1. The document discusses different taxonomic classifications including alpha, beta, and gamma taxonomy. It also mentions phylogenetic and neo taxonomy.
2. Several plant families are listed including Brassicaceae, Boraginaceae, and Asteraceae. Characteristics of different plant families like flower structure and leaf arrangements are provided.
3. Examples of plant species are given, such as Sagittaria cuneata, Alisma triviale, and Arenga australasica. Traits of monocots like herbaceous stems and lack of endosperm are mentioned.
Apple was founded in 1976 by Steve Jobs, Steve Wozniak, and Ronald Wayne. It started as a computer company and is now a multinational technology company that produces consumer electronics, computer software, and online services. Apple's major products include the iPhone, iPad, Mac computers, iPod, and Apple's online stores like the iTunes Store. Apple has become the largest publicly traded company in the world by market capitalization and is the largest technology company by revenue and profit.
The document summarizes key aspects of the Sale of Goods Act 1930 in India. It defines important terms like sale, agreement to sell, goods, and conditions vs warranties. It also outlines implied conditions and warranties, as well as rules around transfer of property, delivery, unpaid sellers' rights, and auction sales. The Act establishes important distinctions between different types of contracts and rights/obligations of buyers and sellers.
The document discusses key aspects of India's first five-year plan presented by Jawahar Lal Nehru after independence. It allocates funds to sectors like agriculture, transportation and aims for GDP growth of 2.1% which was surpassed at 3.6%. Infrastructure projects like dams were also initiated. National income grew due to factors like increased crop yields but population growth reduced the per capita income growth.
Perang Dunia I adalah perang global yang terjadi di Eropa antara tahun 1914-1918 yang melibatkan sekutu seperti Inggris, Prancis, Rusia melawan kekuatan poros seperti Jerman, Austria-Hongaria. Konflik ini menewaskan lebih dari 9 juta tentara dan mengakhiri kekuasaan empayar-empayar besar seperti Jerman dan Rusia.