Dr. Emmanuel Dupont is a highly accomplished Senior Research Fellow and Lecturer with over 25 years of experience in cardiovascular research. He has an international reputation in the field of intercellular communication in the cardiovascular system and has published extensively. Currently he is a Senior Research Fellow at Imperial College London where he formulates hypotheses, supervises students, writes grants and papers, and ensures licensing requirements are met. Previously he held roles as Senior Lecturer at the University of Surrey and Research Fellow at Imperial College London where he contributed to numerous publications and supervised students and grants.

1. Emmanuel Dupont - Research Scientist / Senior Research Fellow / Lecturer
Dr Emmanuel Dupont
Research Scientist | Senior Research Fellow
1 Hill View Court, Woking, Surrey GU22 7QN
07522 373612 | emman.dupont@gmail.com | LinkedIn
Profile
A committed, diligent and pioneering Senior Research Fellow with an outstanding academic background, a
substantial publication record and extensive experience in the field of intercellular communication in the
cardiovascular system. Combines a natural flair for building productive working relationships with flexibility,
accuracy and calmness and the skill to prioritise and solve complex problems. Exhibits a finely tuned ability to
adapt, optimise and associate techniques in order to answer specific scientific questions. Ably supports
researchers through advanced team leadership, mentoring and supervision qualities. Works well both
independentlyandas part of a cohesive team demonstrating the motivation and organisation required to meet
demanding targets and challenging deadlines.
MotivatedResearchScientist withaninternational reputationas a specialistinthe fieldofresearch gained
over the years and through various publications and conference presentations
Recognisedasa BritishHeart Foundation (BHF) Master / PhD supervisor for the BHF Centre for Excellence
SeniorResearchFellow adeptat combiningexpertise andthe bestresearch to form the whole picture and
gain insights / ideas previously not thought about
Skills Matrix
Researchmanagement |researchdevelopment | full research lifecycle | hypotheses formulation | hypotheses
verification | funding management | funding development | student development | teaching | mentoring |
studentengagement|processimprovement|scientificpaperwriting | research support | team building | team
development | problem resolution | issue resolution | lecturing | leadership | lead supervision | PhD | grant
applications |academicmanagement|academicdevelopment | academic supervision | project management |
projectplanning|projectdelivery|strategicthinking|strategicplanning| budgetmanagement|budgetcontrol
| communication| presentations|academicwriting | research and development | cell biology | immunology |
biochemistry | morphology | molecular biology | root cause analysis |
Personal Attributes
Ambitious, meticulous and dedicated professional with team player attributes
Decisive, diplomatic and shrewd Research Scientist
Adaptable, sceptical and knowledgeable with a risk-taking attitude
Career Detail
Imperial College London - Senior Research Fellow Nov 2012 - Present
Senior Research Fellow highly regarded as a specialist in the field of intercellular communication in the
cardiovascular system and its malfunction in diseases affecting this system (cardiac arrhythmias and
atherosclerosis). Primarilytaskedwith formulatingscientifichypothesesandverifyingthemusingthe mostrecent
technologiesandhuman expertise. Additionally writinggrantapplicationstosecure external andinternal funding
with 1 application currently being considered by the British Heart Foundation.
Other Senior Research Fellow highlights are:
 Clearlyandconcisely supervisingandgalvanising5studentsandjuniorresearchers uptopost-doctoral level
 Writingdetailedandaccurate peer-reviewedscientificpapersforpublicationwith 3paperspublishedsofar
and 3 more submitted
 Demonstratingexcellentadaptable and optimisation techniquesto answerscientific questions resulting in
conference presentations and publications
 Ensuringlicensingrequirementsrelatingtothe use of animalsandgeneticallymodified organisms are fully
updated and clarified
University of Surrey - Senior Lecturer Oct 2009 - Oct 2012
Senior Lecturer who meticulously prepared and produced high impact educational programmes and research
support for students presented in an appealing and persuasive format. Evaluated students on attainment,
constantly monitored progress and gave constructive oral and written feedback. Maximised student potential

2. Emmanuel Dupont - Research Scientist / Senior Research Fellow / Lecturer
through rigorous teaching techniques enabling them to achieve the highest grades possible. Coordinated the
dissertationmodulesof the Clinical Biochemistry MSc and the Pharmaceutical Medicine / Clinical Pharmacology
MSc. Further Senior Lecturer accomplishments and duties entailed:
 Establishedaresearchgroupto investigatethe role of intercellular communication in inflammation of the
blood vessels resulting in the award of 2 successful PhD theses
 Tasked as lead supervisor for 7 BSc / MSc students for their dissertation projects
 Memberof 2 examinationboardsand 2 studyboards - Clinical BiochemistryandPharmaceutical Medicine /
Clinical Pharmacology MSc
 Lectured in communication skills engaging and nurturing students to achieve their best by teaching to an
exacting standard and ensuring all course content was fully covered and understood
Imperial College London - Research Fellow Feb 1995 - Oct 2009
Research Fellow who ably and expertly contributed to the body of knowledge in the field of intercellular
communicationinthe cardiovascularsystem. Draftedcomprehensive grantapplications forexternal and internal
fundingwhichsecured14successful applications. Adaptedandoptimisedtechniques inordertoanswerscientific
questions leading to publications and conference presentations. Other Research Fellow achievements were:
 Compiled peer-reviewed scientific papers for over 50 journal publications
 Supervised and motivated junior researchers across all levels up to post-doctoral including offering
guidance andsupport to 6 undergraduate students and officially supervised 8 PhD theses awarded within
the 4 years deadline
 Ensuredlicensingrequirements relating to use of animals and genetically modified organisms were up to
date as well as giving lectures as a research lecturer
Centre Medical Universitaire, Geneva - Research and Teaching Assistant Oct 1992 - Oct 1994
Michigan State University, USA - Research Associate Oct 1989 - Sep 1992
Peer Reviewed Articles - From 1988 to present, see appendix
Book Chapters Reviews
Remodelling of gap junctions and connexin expression in diseased myocardium, NJ Severs, AF Bruce, E
Dupont, S Rothery. Cardiovasc Res., 80, 9 - 19 (2008)
Gap junction channels and cardiac impulse propagation, T Desplantez, E Dupont, NJ Severs, R Weingart. J
Membr Biol., 218, 13 - 28 (2007)
Alterations in cardiac connexin expression in cardiomyopathies, NJ Severs, E Dupont, N Thomas, R Kaba, S
Rothery, R Jain, K Sharpey, CH Fry. Adv Cardiol., 42, 228 - 242 (2006)
Gap junction and connexin remodelling in human heartdisease,NJ Severs, E Dupont, R Kaba, N Thomas. In:
‘Gap Junctions in Development and Disease’. Edited by E Winterhager, Heidelberg, 57 - 83 (2005)
Gap junction alterations in human cardiac disease, NJ Severs, SR Coppen, E Dupont, HI Yeh, YS Ko, T
Matsushita. Cardiovasc Res. 62, 368 - 377 (2004)
Remodelling of gap junctions and connexin expression in heart disease, NJ Severs, E Dupont, SR Coppen, D
Halliday, E Inett, D Baylis, S Rothery. Biochim. Biophys. Acta, 1662, 138 - 148 (2004)
Re: The sinoatrial node, connexin distribution patterns and specific immunodetection of connexin45, SR
Coppen, E Dupont, NJ Severs. Cardiovasc. Res., 53, 1043 - 1045 (2002). Author reply.
Immunocytochemical Analysis of Connexin Expression in the Healthy and Diseased Cardiovascular System,
NJSevers,S Rothery,E Dupont,SR Coppen,H-I Yeh, Y-S Ko, T Matsushita, R Kaba, D Halliday. Microsc. Res.
Tech., 52, 301 - 322 (2001)
SimultaneousLocalization of Connexins40,37 and 43 in Pulmonary Artery EndothelialGap Junctions, YS Ko,
H-I Yeh,S Rothery, E Dupont, NJ Severs. In: Proceedings 1997 International Gap Junction Conference, ISO
Publishers (1997)
Gap Junction and Connexinsin theCardiovascularSystem, NJSevers,EDupont,RR Kaprielian, H-I Yeh and S
Rothery. Annual of Cardiac Surgery, 9th edition, 31 - 44 (1996)
Intercellular Communication: A Paradigm for the Interpretation of the Initiation / Promotion / Progression
Model of Carcinogenesis, JE Trosko, CC Chang, BV Madhukar and E Dupont. In ‘Chemical induction of
cancer’. Edited by JC Arcos, Birkhauser publisher, 205 - 225 (1996)
Gland Cell Connexins, PMeda,C Vozzi,S Ullrich,E Dupont, A Charollais, E Sutter, D Bosco. Progress in Cell
Research, Vol. 4, 281 - 287 (1995)

3. Emmanuel Dupont - Research Scientist / Senior Research Fellow / Lecturer
Oncogenes, Tumour Suppressor Genes and Intercellular Communication in the Oncogeny as Partially
Blocked Ontogeny Hypothesis, JE Trosko, CC Chang, BV Madhukar and E Dupont. In: ‘New Frontiers in
Cancer Causation’, IVERSEN editor, TAYLOR and FRANCIS publishers, Washington DC, 181 - 197 (1993)
Suppression of Gap Junctional Gene Expression by Growth Factors and TPA in Human Epidermal
Keratinocytes in Vitro, E Dupont, BV Madhukar and JE Trosko. Progress in Cell Research, Vol 3, 321 - 327
(1993)
Chemical Modulation of Gap Junctional Intercellular Communication in Vitro: An in Vitro Biomarker of
Epigenetic Toxicology, JE Trosko, CC Chang, E Dupont, BV Madhukar and G Kalimi. In Vitro methods in
toxicology, 465-478 (1992)
Invited Lectures
Relating connexin co-expression and connexon structure to cardiac gap junction function, Laboratorio de
Investigación Cardiovascular, Servicio de Cardiología, Hospitals Vall d'Hebron, Barcelona, Spain (2008)
Relating Connexin Co-expression and Connexon Structure to Cardiac Gap Junction Function, The Swiss
Cardiovascular Research and Training Network, University of Bern, Switzerland, (2007)
Relating Connexin Co-expression and Connexon Structure to Cardiac Gap Junction Function, Wales Heart
Research Institute, Cardiff University School of Medicine, Cardiff, UK (2007)
Structural Aspects of Gap Junctions, Department of Physiology, University of Bern, Switzerland (2006)
Connexins and Heart Failure, 3rd James Black Conference, British Pharmacological Society, Oxford (2005)
Gap Junction Remodelling in Heart Failure, Lojda Symposium on Basic, Diagnostic and Applied
Histochemistry, Kosice, Slovakia (2004)
Gap Junction Remodelling in Heart Failure, 24th Meeting of the European Section of the International
Society for Heart Research. Dresden, Germany (2004)
Gap Junctionsand StructuralChangesin Heart Failure, Heart Failure 2001, 4th International Meeting of the
Working Group of the European Society of Cardiology, Barcelona, Spain (2001)
Patent
UK Patent Application N0 9920277.2: ‘Diagnostic Method’. Describe the invention of a diagnostic test to
peri-operatively predict post-operative atrial fibrillation in a patient undergoing heart or heart and lung
surgery. E Dupont, Y-S Ko, SR Coppen, MP Haw and NJ Severs
Education and Qualifications
PhD in cell biology: Gap Junctions or Communicating Junctions: Use of Antipeptide Antibodies for the
immuno-detection and immuno-purification of Junctional Proteins, University of Aix-Marseille II, France
(1989)
MRes (DEA), Distinction, University of Poitiers, France (1985)
MSc in Physiology and Pharmacology, University of Poitiers, France (1984)
BSc in Cell Biology and Physiology, Distinction, University of Poitiers, France (1983)
Languages - Fluent English and French (mother tongue)
IT Proficiency - Microsoft Office suite including PowerPoint; Prism; FIJI; internet resources enabling sequence
comparison (protein and DNA) and reference search (PubMed)
Hobbies and Interests
Awayfrom my career as a Senior Research Fellow, I enjoy skiing when time allows and watching science fiction
movies .
References are available upon request