This document discusses risks and opportunities in logistics and e-commerce arising from trends like population aging, the millennial generation entering the workforce, and increasing automation. It proposes responses like developing fully automated warehouses and driverless delivery vehicles, adopting blockchain technology, improving predictive analytics and coordination between transport modes, and focusing on high-quality last-mile delivery experiences for customers. Organizations are encouraged to partner with clients, innovate new solutions, and transform their operations to adapt to ongoing changes.