E-reading at night can negatively impact sleep, health, and circadian rhythms. A study found that using light-emitting e-devices like e-books before bed delayed sleep onset, reduced evening sleepiness, lowered melatonin levels, and resulted in feeling less alert in the morning compared to reading printed books. The blue light emitted from devices suppresses melatonin secretion and disrupts the body's natural sleep-wake cycle. Previous research has shown blue light's powerful effects on sleep, and this study's findings suggest e-device use right before bed may exacerbate sleep deficiencies.
Iotswc2016 - Microsoft - Healthcare track - lombardi - KHAREallo75
KHARE is a rehabilitation solution to speed up the recovery process for injured people: using Kinect, Microsoft Band and an IoT architecture on Azure, the human telemetry supports physiatrists and neuroscience researchers in tracking movements of exercises and predicting rehab trends. The body telemetry of a patient allows for experimentation with new rehabilitation modalities using mirror neurons.
* This is the presentation made at IoT Solution World Congress (IOTSWC) 2016 in the healthcare track
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Iotswc2016 - Microsoft - Healthcare track - lombardi - KHAREallo75
KHARE is a rehabilitation solution to speed up the recovery process for injured people: using Kinect, Microsoft Band and an IoT architecture on Azure, the human telemetry supports physiatrists and neuroscience researchers in tracking movements of exercises and predicting rehab trends. The body telemetry of a patient allows for experimentation with new rehabilitation modalities using mirror neurons.
* This is the presentation made at IoT Solution World Congress (IOTSWC) 2016 in the healthcare track
Sales: +91 98336 70220; Unishire Terraza is spread across 2 acres and host about 182 apartments in G+14 floors. Expected official launch by 15th Jan. It offers 2 BHK, 3 BHK, 3.5 BHK and 4 BHK lavish residences at reasonable prices. For more information visit Igotmydeal.com or call us on +91 98336 70220
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Objective and Study Design: This was a cross-sectional study purposed to observe the effects of led bulbs and artificial lights on human health and its physiological considerations on sleep.
Our study addressed two goals. Our first goal was to determine the extent to which light pollution was perceived as a problem by the people. Our second goal was to recommend
applicable lighting ordinances for reducing light pollution. Material and Methods: This study was conducted at All India Institute of Medical Sciences hospital, Bhopal and Narayana medical college, Nellore during the period between May 2014 and August 2015. Three hundred human volunteers, 123 female and 177 male, ages of 18 and 55 were studied in a two-part experiment, which included one Sleep questionnaire regarding light pollution to study each individual's
normal body conditions, and an Assay of melatonin in saliva. Results: The results showed that many participants have a long history of sleeping problems. They usually take at least an hour to fall asleep and tend to wake up frequently throughout the night and feel poorly rested in the morning. The salivary melatonin levels also declined at night due to progressive exposure to artificial light. Conclusion: Through our research, we have obtained data that strongly suggest that light pollution is adversely affecting public health, causing them to experience sleep loss, visual fatigue, weariness, anxiety, and depression.
This report examines how digital technologies are impacting human cognition, neurology and behaviour. It is based on interviews with four globally recognised experts spanning the fields of neuroscience and behavioural psychology.
Evening use of light-emitting eReaders negativelyaffects sle.docxturveycharlyn
Evening use of light-emitting eReaders negatively
affects sleep, circadian timing, and
next-morning alertness
Anne-Marie Changa,b,1,2, Daniel Aeschbacha,b,c, Jeanne F. Duffya,b, and Charles A. Czeislera,b
aDivision of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA 02115; bDivision of Sleep
Medicine, Harvard Medical School, Boston, MA 02115; and cInstitute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany
Edited by Joseph S. Takahashi, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, and approved November 26,
2014 (received for review September 24, 2014)
In the past 50 y, there has been a decline in average sleep duration
and quality, with adverse consequences on general health. A
representative survey of 1,508 American adults recently revealed
that 90% of Americans used some type of electronics at least
a few nights per week within 1 h before bedtime. Mounting
evidence from countries around the world shows the negative
impact of such technology use on sleep. This negative impact on
sleep may be due to the short-wavelength–enriched light emitted
by these electronic devices, given that artificial-light exposure has
been shown experimentally to produce alerting effects, suppress
melatonin, and phase-shift the biological clock. A few reports have
shown that these devices suppress melatonin levels, but little is
known about the effects on circadian phase or the following sleep
episode, exposing a substantial gap in our knowledge of how this
increasingly popular technology affects sleep. Here we compare
the biological effects of reading an electronic book on a light-emit-
ting device (LE-eBook) with reading a printed book in the hours
before bedtime. Participants reading an LE-eBook took longer to
fall asleep and had reduced evening sleepiness, reduced melatonin
secretion, later timing of their circadian clock, and reduced next-
morning alertness than when reading a printed book. These results
demonstrate that evening exposure to an LE-eBook phase-delays
the circadian clock, acutely suppresses melatonin, and has important
implications for understanding the impact of such technologies on
sleep, performance, health, and safety.
sleep | chronobiology | phase-shifting | digital media | electronics
The use of electronic devices for reading, communication, andentertainment has greatly increased in recent years. Greater
portability, convenience, and ease of access to reading materials
in electronic form add to the popularity of these devices. The use
of light-emitting devices immediately before bedtime is a con-
cern because light is the most potent environmental signal that
impacts the human circadian clock and may therefore play a role
in perpetuating sleep deficiency (1). The circadian-timing system
synchronizes numerous internal physiological and biochemical
processes, including the daily rhythm of sleep propensity (2).
A Call to Action: Improving brain & mental health via digital platforms,...SharpBrains
(Session held at the 2014 SharpBrains Virtual Summit; October 28-30th, 2014)
8:15–9:45am. A Call to Action: Improving brain & mental health via digital platforms, neuroplasticity research and the White House BRAIN initiative
- Dr. Thomas Insel, Director of the National Institute of Mental Health (NIMH)
- Dr. Adam Gazzaley, Director of UCSF Neuroscience Imaging Center and Co-founder of Akili Interactive Labs
- Dr. Daphne Bavelier, Head of the Brain & Learning Lab at the University of Geneva & U. of Rochester
- Jack Young, Head of Qualcomm Life Fund
- Chair: Alvaro Fernandez, CEO of SharpBrains
Learn more here:
http://sharpbrains.com/summit-2014/agenda/
Objective and Study Design: This was a cross-sectional study purposed to observe the effects of led bulbs and artificial lights on human health and its physiological considerations on sleep.
Our study addressed two goals. Our first goal was to determine the extent to which light pollution was perceived as a problem by the people. Our second goal was to recommend
applicable lighting ordinances for reducing light pollution. Material and Methods: This study was conducted at All India Institute of Medical Sciences hospital, Bhopal and Narayana medical college, Nellore during the period between May 2014 and August 2015. Three hundred human volunteers, 123 female and 177 male, ages of 18 and 55 were studied in a two-part experiment, which included one Sleep questionnaire regarding light pollution to study each individual's
normal body conditions, and an Assay of melatonin in saliva. Results: The results showed that many participants have a long history of sleeping problems. They usually take at least an hour to fall asleep and tend to wake up frequently throughout the night and feel poorly rested in the morning. The salivary melatonin levels also declined at night due to progressive exposure to artificial light. Conclusion: Through our research, we have obtained data that strongly suggest that light pollution is adversely affecting public health, causing them to experience sleep loss, visual fatigue, weariness, anxiety, and depression.
This report examines how digital technologies are impacting human cognition, neurology and behaviour. It is based on interviews with four globally recognised experts spanning the fields of neuroscience and behavioural psychology.
Evening use of light-emitting eReaders negativelyaffects sle.docxturveycharlyn
Evening use of light-emitting eReaders negatively
affects sleep, circadian timing, and
next-morning alertness
Anne-Marie Changa,b,1,2, Daniel Aeschbacha,b,c, Jeanne F. Duffya,b, and Charles A. Czeislera,b
aDivision of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA 02115; bDivision of Sleep
Medicine, Harvard Medical School, Boston, MA 02115; and cInstitute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany
Edited by Joseph S. Takahashi, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, and approved November 26,
2014 (received for review September 24, 2014)
In the past 50 y, there has been a decline in average sleep duration
and quality, with adverse consequences on general health. A
representative survey of 1,508 American adults recently revealed
that 90% of Americans used some type of electronics at least
a few nights per week within 1 h before bedtime. Mounting
evidence from countries around the world shows the negative
impact of such technology use on sleep. This negative impact on
sleep may be due to the short-wavelength–enriched light emitted
by these electronic devices, given that artificial-light exposure has
been shown experimentally to produce alerting effects, suppress
melatonin, and phase-shift the biological clock. A few reports have
shown that these devices suppress melatonin levels, but little is
known about the effects on circadian phase or the following sleep
episode, exposing a substantial gap in our knowledge of how this
increasingly popular technology affects sleep. Here we compare
the biological effects of reading an electronic book on a light-emit-
ting device (LE-eBook) with reading a printed book in the hours
before bedtime. Participants reading an LE-eBook took longer to
fall asleep and had reduced evening sleepiness, reduced melatonin
secretion, later timing of their circadian clock, and reduced next-
morning alertness than when reading a printed book. These results
demonstrate that evening exposure to an LE-eBook phase-delays
the circadian clock, acutely suppresses melatonin, and has important
implications for understanding the impact of such technologies on
sleep, performance, health, and safety.
sleep | chronobiology | phase-shifting | digital media | electronics
The use of electronic devices for reading, communication, andentertainment has greatly increased in recent years. Greater
portability, convenience, and ease of access to reading materials
in electronic form add to the popularity of these devices. The use
of light-emitting devices immediately before bedtime is a con-
cern because light is the most potent environmental signal that
impacts the human circadian clock and may therefore play a role
in perpetuating sleep deficiency (1). The circadian-timing system
synchronizes numerous internal physiological and biochemical
processes, including the daily rhythm of sleep propensity (2).
A Call to Action: Improving brain & mental health via digital platforms,...SharpBrains
(Session held at the 2014 SharpBrains Virtual Summit; October 28-30th, 2014)
8:15–9:45am. A Call to Action: Improving brain & mental health via digital platforms, neuroplasticity research and the White House BRAIN initiative
- Dr. Thomas Insel, Director of the National Institute of Mental Health (NIMH)
- Dr. Adam Gazzaley, Director of UCSF Neuroscience Imaging Center and Co-founder of Akili Interactive Labs
- Dr. Daphne Bavelier, Head of the Brain & Learning Lab at the University of Geneva & U. of Rochester
- Jack Young, Head of Qualcomm Life Fund
- Chair: Alvaro Fernandez, CEO of SharpBrains
Learn more here:
http://sharpbrains.com/summit-2014/agenda/
The aim of this review is to summarize the current research studies on dissolvable brain implant consisting of pressure and temperature sensors that can monitor traumatic brain injury and Parkinson’s disease.Full articles with each line detailing available @pharmacyhighlights.com
The Science of Sweet Dreams: Predicting Sleep Efficiency from Wearable Devic...Luis Fernandez Luque
Lack of sleep can erode mental and physical well-being, often exacerbating health problems such as obesity. Wearable devices that capture and analyze sleep quality through predictive methodologies can help patients and medical practitioners make behavioral health decisions that can lead to better sleep and improved health.
http://doi.ieeecomputersociety.org/10.1109/MC.2017.91
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
2. Contd..
Use of a light-emitting electronic device
such as e-books in the hours before
bedtime can adversely impact sleep,
overall health, alertness and the circadian
clock, a new study has found.
Researchers at Brigham and Women's
Hospital (BWH) compared the biological
effects of reading a light-emitting
electronic device (LEeBook) compared to a
printed book.
3. Contd..
“We found the body's natural circadian
rhythms were interrupted by the short-
wavelength enriched light, otherwise known
as blue light, from these electronic devices,“
said Anne-Marie Chang, corresponding
author, and associate neuroscientist in BWH's
Division of Sleep and Circadian Disorders.
“Participants reading an LE-eBook took longer
to fall asleep and had reduced evening
sleepiness, reduced melatonin secretion, later
timing of their circadian clock and reduced
next-morning alertness than when reading a
printed book,“ Chang said.
4. Contd..
Previous research has shown that blue light
suppresses melatonin, impacts the circadian clock
and increases alertness, but little was known about
the effects of this popular technology on sleep. The
iPad readers had reduced secretion of melatonin.
The use of light emitting devices immediately before
bedtime is a concern because of the extremely
powerful effect that light has on the body's natural
sleepwake pattern, and may thereby play a role in
perpetuating sleep deficiency . Although iPads were
used in this study, researchers also measured
laptops, cell phones, LED monitors, and other
eReaders, all emitting blue light.
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