This research report evaluates the attitudes of general practitioners and specialists toward the National Institute for Health and Care Excellence (NICE) regarding its appraisal system and guidelines. Key findings include a significant number of respondents believing NICE's decisions prioritize cost-effectiveness over patient outcomes, along with low familiarity with NICE's medicines and prescribing regulations. The report also highlights the potential influence of publishing prescribing uptake data on prescribing behaviors among healthcare professionals.