The document summarizes 63 problem statements from various organizations in the Indian defence sector for the Defence India Start-up Challenge 10 (DISC 10). The problem statements are grouped by the issuing organization and cover domains including automatic topographic feature extraction, combat parachute safety devices, digital cockpit systems, naval engineering tools, underwater targeting, naval intelligence networks, hypoxic training equipment, radar domes, weather prediction, and colored smoke for aerobatic demonstrations. The goal of DISC 10 is to foster innovation by startups to address technical challenges faced by the defence organizations.